Lista de obras -

Antimalarial and anticancer activities of artemisinin-quinoline hybrid-dimers and pharmacokinetic properties in mice.

artículo científico publicado en 2012

Antiplasmodial properties of acyl-lysyl oligomers in culture and animal models of malaria.

artículo científico publicado en 2011

Choline analogues in malaria chemotherapy

artículo científico publicado en 2012

Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite

artículo científico publicado en 2018

Design and synthesis of amidoxime derivatives for orally potent C-alkylamidine-based antimalarial agents.

artículo científico publicado en 2008

Development of the first oral bioprecursors of bis-alkylguanidine antimalarial drugs.

artículo científico publicado en 2014

Disulfide prodrugs of albitiazolium (T3/SAR97276): synthesis and biological activities.

artículo científico publicado en 2012

Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials

artículo científico publicado en 2019

Evaluation of bis-alkylamidoxime O-alkylsulfonates as orally available antimalarials.

artículo científico publicado en 2012

Exploration of potential prodrug approach of the bis-thiazolium salts T3 and T4 for orally delivered antimalarials.

artículo científico publicado en 2010

Exploring prodrug approaches for albitiazolium and its analogues.

artículo científico publicado en 2014

Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites

artículo científico publicado en 2020

High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death.

artículo científico publicado en 2017

Hydroxyl Ketone-Based Histone Deacetylase Inhibitors To Gain Insight into Class I HDAC Selectivity versus That of HDAC6.

artículo científico publicado en 2017

Mediation of annexin 1 secretion by a probenecid-sensitive ABC-transporter in rat inflamed mucosa.

artículo científico publicado en 2004

New bis-thiazolium analogues as potential antimalarial agents: design, synthesis, and biological evaluation

scientific article published on 04 January 2013

New insight into the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium, a new type of antimalarial.

artículo científico publicado en 2014

Pharmacokinetic properties and metabolism of a new potent antimalarial N-alkylamidine compound, M64, and its corresponding bioprecursors ⬇️

artículo científico publicado el 2 de noviembre de 2010

Phenobarbital induces cytochrome P4501A2 hnRNA, mRNA and protein in the liver of C57BL/6J wild type and aryl hydrocarbon receptor knock-out mice

scientific article published on 01 March 1998

Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues

scientific article published on 25 April 2019

Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids.

artículo científico publicado en 2013

Quantitative analysis of a bis-thiazolium antimalarial compound, SAR97276, in mouse plasma and red blood cell samples, using liquid chromatography mass spectrometry.

artículo científico publicado en 2007

Reliability of antimalarial sensitivity tests depends on drug mechanisms of action.

artículo científico publicado en 2010

Reverse-benzamidine antimalarial agents: design, synthesis, and biological evaluation

artículo científico publicado en 2010

Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways.

artículo científico publicado en 2010

Synthesis and evaluation of hybrid bis-cationic salts as antimalarial drugs.

artículo científico publicado en 2010

Synthesis of an Uncharged Tetra-cyclopeptide Acting as a Transmembrane Carrier: Enhanced Cellular and Nuclear Uptake

artículo científico publicado en 2017

Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny

artículo científico publicado en 2018

Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate

artículo científico publicado en 2012

Lista de obras de

Antimalarial and anticancer activities of artemisinin-quinoline hybrid-dimers and pharmacokinetic properties in mice.

Antiplasmodial properties of acyl-lysyl oligomers in culture and animal models of malaria.

Choline analogues in malaria chemotherapy

Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite

Design and synthesis of amidoxime derivatives for orally potent C-alkylamidine-based antimalarial agents.

Development of the first oral bioprecursors of bis-alkylguanidine antimalarial drugs.

Disulfide prodrugs of albitiazolium (T3/SAR97276): synthesis and biological activities.

Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials

Evaluation of bis-alkylamidoxime O-alkylsulfonates as orally available antimalarials.

Exploration of potential prodrug approach of the bis-thiazolium salts T3 and T4 for orally delivered antimalarials.

Exploring prodrug approaches for albitiazolium and its analogues.

Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites

High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death.

Hydroxyl Ketone-Based Histone Deacetylase Inhibitors To Gain Insight into Class I HDAC Selectivity versus That of HDAC6.

Mediation of annexin 1 secretion by a probenecid-sensitive ABC-transporter in rat inflamed mucosa.

New bis-thiazolium analogues as potential antimalarial agents: design, synthesis, and biological evaluation

New insight into the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium, a new type of antimalarial.

Pharmacokinetic properties and metabolism of a new potent antimalarial N-alkylamidine compound, M64, and its corresponding bioprecursors ⬇️

Phenobarbital induces cytochrome P4501A2 hnRNA, mRNA and protein in the liver of C57BL/6J wild type and aryl hydrocarbon receptor knock-out mice

Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues

Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids.

Quantitative analysis of a bis-thiazolium antimalarial compound, SAR97276, in mouse plasma and red blood cell samples, using liquid chromatography mass spectrometry.

Reliability of antimalarial sensitivity tests depends on drug mechanisms of action.

Reverse-benzamidine antimalarial agents: design, synthesis, and biological evaluation

Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways.

Synthesis and evaluation of hybrid bis-cationic salts as antimalarial drugs.

Synthesis of an Uncharged Tetra-cyclopeptide Acting as a Transmembrane Carrier: Enhanced Cellular and Nuclear Uptake

Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny

Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate