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Lista de obras de Samuel Waxman

12-O-tetradecanoyl-phorbol-13-acetate release of glycosyltransferases from human blood cells

artículo científico publicado en 1980

A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.

artículo científico publicado en 2006

A retinoid/butyric acid prodrug overcomes retinoic acid resistance in leukemias by induction of apoptosis ⬇️

artículo científico publicado el 1 de octubre de 2003

Advances in the management of acute promyelocytic leukemia and other hematologic malignancies with arsenic trioxide

artículo científico publicado en 2002

Aggravation or Initiation of Megaloblastosis by Amino Acids in the Diet ⬇️

artículo científico publicado el 5 de octubre de 1970

All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia

artículo científico publicado en 2004

Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations

artículo científico publicado en 1999

Appearance of C-type virus-like particles after co-cultivation of a human tumor-cell line with rat (XC) cells ⬇️

artículo científico publicado el 15 de septiembre de 1975

Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells

artículo científico publicado en 1998

Arsenic trioxide in multiple myeloma: rationale and future directions

artículo científico publicado en 2002

Arsenic trioxide inhibits growth of human multiple myeloma cells in the bone marrow microenvironment.

artículo científico publicado en 2002

Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway

artículo científico publicado en 1999

Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression

artículo científico publicado en 2009

Benzodithiophenes induce differentiation and apoptosis in human leukemia cells

artículo científico publicado en 2005

Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regu

artículo científico publicado en 2005

Bexarotene plus erlotinib suppress lung carcinogenesis independent of KRAS mutations in two clinical trials and transgenic models

artículo científico publicado en 2011

Bortezomib enhances the efficacy of fulvestrant by amplifying the aggregation of the estrogen receptor, which leads to a proapoptotic unfolded protein response

artículo científico publicado en 2011

Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells

artículo científico publicado en 2005

Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors

artículo científico publicado en 2006

CD44 ligation with A3D8 antibody induces apoptosis in acute myeloid leukemia cells through binding to CD44s and clustering lipid rafts ⬇️

artículo científico publicado el 16 de agosto de 2012

Characterization of sialyltransferase activity from human placenta

artículo científico publicado en 1978

Cloning of a gene (RIG-G) associated with retinoic acid-induced differentiation of acute promyelocytic leukemia cells and representing a new member of a family of interferon-stimulated genes

artículo científico publicado en 1997

Combination of cytotoxic-differentiation therapy with 5-fluorouracil and phenylbutyrate in patients with advanced colorectal cancer.

artículo científico publicado en 2007

Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model

artículo científico publicado en 2006

DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia

artículo científico publicado en 2007

De-regulation of common housekeeping genes in hepatocellular carcinoma

artículo científico publicado en 2007

Defective expression of cellular retinol binding protein type I and retinoic acid receptors alpha2, beta2, and gamma2 in human breast cancer cells

artículo científico publicado en 1996

Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics

artículo científico publicado en 2008

Differentiation therapy of acute myeloid leukemia: past, present and future

artículo científico publicado en 2009

Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxa-mediated pathway requiring iron and endoperoxide moiety

artículo científico publicado en 2015

Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha

artículo científico publicado en 1999

Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells ⬇️

artículo científico publicado el 3 de julio de 2012

Drugs, toxins and dietary amino acids affecting vitamin B12 or folic acid absorption or utilization

artículo científico publicado en 1970

Dual effects of glutathione-S-transferase pi on As2O3 action in prostate cancer cells: enhancement of growth inhibition and inhibition of apoptosis

artículo científico publicado en 2004

Effect of intracellular folate concentration on the modulation of 5-fluorouracil cytotoxicity by the elevation of phosphoribosylpyrophosphate in cultured human KB cells

artículo científico publicado en 1987

Effect of retinoic acid isomers on proliferation, differentiation and PML relocalization in the APL cell line NB4.

artículo científico publicado en 1995

Emerging Roles of Epigenetic Regulator Sin3 in Cancer

artículo científico publicado en 2016

Ethacrynic Acid and a Derivative Enhance Apoptosis in Arsenic Trioxide–Treated Myeloid Leukemia and Lymphoma Cells: The Role of Glutathione S-Transferase P1-1 ⬇️

artículo científico publicado el 18 de octubre de 2012

Evolutionary significance of persistence of latent oncogenic virus information in vertebrates

artículo científico publicado en 1973

Expression of the zinc-finger gene PLZF at rhombomere boundaries in the vertebrate hindbrain

artículo científico publicado en 1995

Fibrolamellar Carcinoma: A Review with Focus on Genetics and Comparison to Other Malignant Primary Liver Tumors ⬇️

artículo científico publicado el 22 de febrero de 2011

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

artículo científico publicado en 2008

Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia

artículo científico publicado en 1993

Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma

artículo científico publicado en 2007

Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene

artículo científico publicado en 1999

Genomic structure of the human PLZF gene

artículo científico publicado en 1999

Glutathione-S-transferase pi inhibits As2O3-induced apoptosis in lymphoma cells: involvement of hydrogen peroxide catabolism

artículo científico publicado en 2004

Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features

artículo científico publicado en 2017

In vitro and in vivo growth and casein gene expression of mouse mammary tumor epithelial cells in response to hormones

artículo científico publicado en 1990

Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells

artículo científico publicado en 1994

Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis

artículo científico publicado en 2005

Influence on immunoreactive folate-binding proteins of extracellular folate concentration in cultured human cells ⬇️

artículo científico publicado el 1 de mayo de 1988

Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes

artículo científico publicado en 2013

Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells

artículo científico publicado en 2010

JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells

artículo científico publicado en 2003

LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling

artículo científico publicado en 2010

Leukemia translocation gene, PLZF, is expressed with a speckled nuclear pattern in early hematopoietic progenitors

artículo científico publicado en 1995

Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies

artículo científico publicado en 1997

Lineage restriction of the RARalpha gene expression in myeloid differentiation

artículo científico publicado en 2001

Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia

scholarly article

Measurement of red cell folate levels by 3H-pteroylglutamic acid (3H-PteGlu) radioassay

artículo científico publicado en 1974

Mechanisms of action of arsenic trioxide.

artículo científico publicado en 2002

Meeting report: the 11th International Conference on Differentiation Therapy and Innovative Therapeutics in Oncology

artículo científico publicado en 2007

Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.

artículo científico publicado en 2003

Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells.

artículo científico publicado en 2003

MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a

artículo científico publicado en 2011

Modified phosphoribosylpyrophosphate (PRPP) radioenzymatic assay: increased sensitivity, technical simplification and new applications

scientific article published on 01 May 1987

Modulation of the antigenic phenotype of human breast carcinoma cells by modifiers of protein kinase C activity and recombinant human interferons

artículo científico publicado el 1 de enero de 1992

Molecular target-based treatment of human cancer: summary of the 10th international conference on differentiation therapy

artículo científico publicado en 2005

Ongoing activity in peripheral nerve: injury discharge

artículo científico publicado en 1974

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors

artículo científico publicado en 1994

Phosphate-induced phosphoribosylpyrophosphate elevations to assess deranged folate and purine nucleotide metabolism

artículo científico publicado en 1987

Pivotal role of mTOR signaling in hepatocellular carcinoma

artículo científico publicado en 2008

RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell

artículo científico publicado en 1996

Rapid induction of cAMP/PKA pathway during retinoic acid-induced acute promyelocytic leukemia cell differentiation

artículo científico publicado en 2004

Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia

artículo científico publicado en 1993

Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia ⬇️

artículo científico publicado el 15 de abril de 1998

Reduction in lactate accumulation correlates with differentiation-induced terminal cell division of leukemia cells* ⬇️

artículo científico publicado el 1 de septiembre de 1991

Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters

artículo científico publicado en 2008

Retinoic acid receptor alpha2 is a growth suppressor epigenetically silenced in MCF-7 human breast cancer cells

artículo científico publicado en 2002

Schizophrenia, epilepsy, cancer, methionine, and folate metabolism. Pathogenesis of schizophrenia ⬇️

artículo científico publicado el 5 de julio de 1975

Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer

artículo científico publicado en 2015

Sorafenib Inhibition of Mcl-1 Accelerates ATRA-Induced Apoptosis in Differentiation-Responsive AML Cells

artículo científico publicado en 2015

Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients

artículo científico publicado en 1999

Synergic effects of arsenic trioxide and cAMP during acute promyelocytic leukemia cell maturation subtends a novel signaling cross-talk

artículo científico publicado en 2002

Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia

artículo científico publicado en 2005

Tamoxifen stimulates the growth of cyclin D1-overexpressing breast cancer cells by promoting the activation of signal transducer and activator of transcription 3.

artículo científico publicado en 2008

Targeted degradation of the AML1/MDS1/EVI1 oncoprotein by arsenic trioxide

artículo científico publicado en 2006

Targeted interference of SIN3A-TGIF1 function by SID decoy treatment inhibits Wnt signaling and invasion in triple negative breast cancer cells

artículo científico publicado en 2016

Targeted removal of PML-RARalpha protein is required prior to inhibition of histone deacetylase for overcoming all-trans retinoic acid differentiation resistance in acute promyelocytic leukemia

artículo científico publicado en 2002

Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer

artículo científico publicado en 2015

Targeting the ubiquitin-proteasome pathway in cancer therapy

artículo científico publicado en 2007

The 12th international conference on differentiation therapy: targeting the aberrant growth, differentiation and cell death programs of cancer cells ⬇️

artículo científico publicado el 7 de enero de 2011

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

artículo científico publicado en 2007

The Promyelocytic Leukemia Zinc Finger Protein Affects Myeloid Cell Growth, Differentiation, and Apoptosis ⬇️

artículo científico publicado el 1 de septiembre de 1998

The cleavage product deltaPML-RARalpha contributes to all-trans retinoic acid-mediated differentiation in acute promyelocytic leukemia cells

artículo científico publicado en 2003

The design of selective and non-selective combination therapy for acute promyelocytic leukemia

artículo científico publicado en 2007

The histone deacetylase 9 gene encodes multiple protein isoforms

artículo científico publicado en 2003

Translocations of the RARalpha gene in acute promyelocytic leukemia

artículo científico publicado en 2001

Unique genomic profile of fibrolamellar hepatocellular carcinoma

artículo científico publicado en 2015

Upregulation of Bfl-1/A1 in leukemia cells undergoing differentiation by all-trans retinoic acid treatment attenuates chemotherapeutic agent-induced apoptosis

artículo científico publicado en 2006

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells

artículo científico publicado en 1997

Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy

artículo científico publicado en 2002

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