Lista de obras -

A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

artículo científico publicado en 2019

A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status.

artículo científico publicado en 2015

A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation

scientific article published on 24 April 2019

A kindred with mutant IKAROS and autoimmunity.

artículo científico publicado en 2018

A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors.

artículo científico publicado en 2006

A novel BaEVRless-pseudotyped γ-globin lentiviral vector drives high and stable HbF expression and improves thalassemic erythropoiesis in vitro

scientific article published on 15 March 2019

A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice.

artículo científico publicado en 2011

A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism

artículo científico publicado en 2018

Advances in foamy virus vector technology and disease correction could speed the path to clinical application

artículo científico publicado en 2012

Advances in the field of lentivector-based transduction of T and B lymphocytes for gene therapy

artículo científico publicado en 2010

Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes

artículo científico publicado en 2016

Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells

artículo científico publicado en 2016

Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency

artículo científico publicado en 2019

Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs.

artículo científico publicado en 2014

Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.

artículo científico publicado en 2016

Baboon envelope pseudotyped lentiviral vectors: a highly efficient new tool to genetically manipulate T-cell acute lymphoblastic leukaemia-initiating cells.

artículo científico publicado en 2016

CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia

scientific article published on 01 January 2020

CD19 and CD20 targeted vectors induce minimal activation of resting B lymphocytes

artículo científico publicado en 2013

CD46 Null Packaging Cell Line Improves Measles Lentiviral Vector Production and Gene Delivery to Hematopoietic Stem and Progenitor Cells

article

Combining T-cell-specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors

artículo científico publicado en 2020

Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China

article

Corrigendum: A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

scientific article published on 04 December 2019

Cyclic dinucleotides modulate human T-cell response through monocyte cell death

artículo científico publicado en 2015

Cytomegalovirus early promoter induced expression of hCD59 in porcine organs provides protection against hyperacute rejection.

artículo científico publicado en 2001

Development of a Model for Chemical Screening Based on Collateral Sensitivity to Target BTK C481S Mutant

scientific article published on 07 April 2020

Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing

Editorial: Gene Therapy for Fanconi Anemia Enters a New Clinical Era.

artículo científico publicado en 2017

Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector

scientific article published on 16 December 2019

Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors.

artículo científico publicado en 2009

Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide.

artículo científico publicado en 2002

Efficient transduction of healthy and malignant plasma cells by lentiviral vectors pseudotyped with measles virus glycoproteins ⬇️

artículo científico publicado el 9 de febrero de 2012

Engineering of α-PD-1 antibody-expressing long-lived plasma cells by CRISPR/Cas9-mediated targeted gene integration

artículo científico publicado en 2020

Engineering the surface glycoproteins of lentiviral vectors for targeted gene transfer

scientific article published on 01 August 2009

Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

artículo científico publicado en 2020

Epigenetic silencing and tissue independent expression of a novel tetracycline inducible system in double-transgenic pigs.

artículo científico publicado en 2006

Epitope dampening monotypic measles virus hemagglutinin glycoprotein results in resistance to cocktail of monoclonal antibodies.

artículo científico publicado en 2013

Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists.

artículo científico publicado en 2015

Erratum: Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727

artículo científico publicado en 2015

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

artículo científico publicado en 2021

Evaluation of retroviral vector design in defined chromosomal loci by Flp-mediated cassette replacement.

artículo científico publicado en 2001

Exclusive Transduction of Human CD4+ T Cells upon Systemic Delivery of CD4-Targeted Lentiviral Vectors

artículo científico publicado en 2015

GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors

artículo científico publicado en 2019

GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism

artículo científico publicado en 2019

GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-κB-dependent induction of HIF-1α.

artículo científico publicado en 2014

Gene Therapy in Fanconi anemia: a matter of time, safety and gene transfer tool efficiency

artículo científico publicado en 2017

Gene therapy for Fanconi anemia: one step closer to the clinic.

artículo científico publicado en 2012

Gene-corrected human Munc13-4-deficient CD8+ T cells can efficiently restrict EBV-driven lymphoproliferation in immunodeficient mice.

artículo científico publicado en 2016

Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.

artículo científico publicado en 2013

Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

scientific article published in Nature Communications

Glut1-mediated glucose transport regulates HIV infection

artículo científico publicado en 2012

HSP110 sustains chronic NF-κB signaling in activated B-cell diffuse large B-cell lymphoma through MyD88 stabilization

artículo científico publicado en 2018

Haploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms

artículo científico publicado en 2016

Hematopoietic stem cell targeting with surface-engineered lentiviral vectors.

artículo científico publicado en 2009

High SYK Expression Drives Constitutive Activation of CD21low B Cells.

artículo científico publicado en 2017

High levels of SOX5 decrease proliferative capacity of human B cells, but permit plasmablast differentiation.

artículo científico publicado en 2014

Human monocyte recognition of adenosine-based cyclic dinucleotides unveils the A2a Gαs protein-coupled receptor tonic inhibition of mitochondrially induced cell death

artículo científico publicado en 2014

Humanized Mice Are Precious Tools for Preclinical Evaluation of CAR T and CAR NK Cell Therapies

scientific article published on 15 July 2020

Humanized mice are precious tools for evaluation of hematopoietic gene therapies and preclinical modeling to move towards a clinical trial

artículo científico publicado en 2019

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.

artículo científico publicado en 2018

IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes

artículo científico publicado en 2002

IL-7R alpha gene expression is inversely correlated with cell cycle progression in IL-7-stimulated T lymphocytes

artículo científico publicado en 2006

Importance of T, NK, CAR T and CAR NK Cell Metabolic Fitness for Effective Anti-Cancer Therapy: A Continuous Learning Process Allowing the Optimization of T, NK and CAR-Based Anti-Cancer Therapies

artículo científico publicado en 2021

Improved lentiviral vectors for Wiskott-Aldrich syndrome gene therapy mimic endogenous expression profiles throughout haematopoiesis.

artículo científico publicado en 2008

In vivo gene delivery into hCD34+ cells in a humanized mouse model

artículo científico publicado en 2011

Lentiviral vector gene transfer into human T cells.

artículo científico publicado en 2009

Lentiviral vectors

artículo científico publicado en 2011

Lentiviral vectors and transduction of human cancer B cells.

artículo científico publicado en 2010

Lentiviral vectors displaying modified measles virus gp overcome pre-existing immunity in in vivo-like transduction of human T and B cells.

artículo científico publicado en 2012

Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics

artículo científico publicado en 2016

Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance.

artículo científico publicado en 2018

Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent

artículo científico publicado en 2017

Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent lymphocytes requires binding to both SLAM and CD46 entry receptors.

artículo científico publicado en 2011

Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis

artículo científico publicado en 2017

Multiplex CRISPR/Cas9 system impairs HCMV replication by excising an essential viral gene.

artículo científico publicado en 2018

Mutations in the H, F, or M Proteins Can Facilitate Resistance of Measles Virus to Neutralizing Human Anti-MV Sera.

artículo científico publicado en 2014

Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.

artículo científico publicado en 2014

Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.

artículo científico publicado en 2017

New approaches towards ex vivo and in vivo gene therapy

artículo científico publicado en 2000

New preclinical models for angioimmunoblastic T-cell lymphoma: filling the GAP

artículo científico publicado en 2020

Novel lentiviral vectors displaying "early-acting cytokines" selectively promote survival and transduction of NOD/SCID repopulating human hematopoietic stem cells.

artículo científico publicado en 2005

Optimized gene transfer into human primary leukemic T cell with NOD-SCID/leukemia-initiating cell activity

artículo científico publicado en 2009

Parkin-Independent Mitophagy Controls Chemotherapeutic Response in Cancer Cells.

artículo científico publicado en 2017

Pharmacological preconditioning protects from ischemia/reperfusion-induced apoptosis by modulating Bcl-xL expression through a ROS-dependent mechanism

scientific article published on 19 December 2020

Production of SIV vectors for gene delivery.

artículo científico publicado en 2011

Production of lentiviruses displaying ''early-acting'' cytokines for selective gene transfer into hematopoietic stem cells.

artículo científico publicado en 2008

RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement

artículo científico publicado en 2014

RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement

Single-chain antibodies that target lentiviral vectors to MHC class II on antigen-presenting cells.

artículo científico publicado en 2009

Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins.

artículo científico publicado en 2008

Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.

artículo científico publicado en 2012

Stem cell gene therapy for fanconi anemia: report from the 1st international Fanconi anemia gene therapy working group meeting.

artículo científico publicado en 2011

Strategies for targeting lentiviral vectors

artículo científico publicado en 2008

Surface engineering of lentiviral vectors for gene transfer into gene therapy target cells

artículo científico

Surface-engineering of lentiviral vectors.

artículo científico publicado en 2004

TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression

artículo científico publicado en 2012

TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage

artículo científico publicado en 2010

TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells

artículo científico publicado en 2013

Targeted retroviral vectors displaying a cleavage site-engineered hemagglutinin (HA) through HA-protease interactions

artículo científico publicado en 2006

Targeting IRAK1 in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2015

The BMI1 polycomb protein represses cyclin G2-induced autophagy to support proliferation in chronic myeloid leukemia cells.

artículo científico publicado en 2015

The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling

artículo científico publicado en 2016

The Future: In Vivo CAR T Cell Gene Therapy

scientific article published on 23 March 2019

Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.

artículo científico publicado en 2016

Twelfth Annual Meeting of the French Society of Cell and Gene Therapy

artículo científico publicado en 2016

Vectofusin-1 Improves Transduction of Primary Human Cells with Diverse Retroviral and Lentiviral Pseudotypes, Enabling Robust, Automated Closed-System Manufacturing

artículo científico publicado en 2019

Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727.

artículo científico publicado en 2014

Vital marking of articular chondrocytes by retroviral infection using green fluorescence protein.

artículo científico publicado en 2002

X-linked primary immunodeficiency associated with hemizygous mutations in the moesin (MSN) gene

scientific journal article

generation of human CD19-CAR T cells results in B-cell depletion and signs of cytokine release syndrome

scientific article published on 01 November 2018

Lista de obras de

A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status.

A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation

A kindred with mutant IKAROS and autoimmunity.

A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors.

A novel BaEVRless-pseudotyped γ-globin lentiviral vector drives high and stable HbF expression and improves thalassemic erythropoiesis in vitro

A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice.

A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism

Advances in foamy virus vector technology and disease correction could speed the path to clinical application

Advances in the field of lentivector-based transduction of T and B lymphocytes for gene therapy

Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes

Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells

Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency

Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs.

Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.

Baboon envelope pseudotyped lentiviral vectors: a highly efficient new tool to genetically manipulate T-cell acute lymphoblastic leukaemia-initiating cells.

CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia

CD19 and CD20 targeted vectors induce minimal activation of resting B lymphocytes

CD46 Null Packaging Cell Line Improves Measles Lentiviral Vector Production and Gene Delivery to Hematopoietic Stem and Progenitor Cells

Combining T-cell-specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors

Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China

Corrigendum: A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

Cyclic dinucleotides modulate human T-cell response through monocyte cell death

Cytomegalovirus early promoter induced expression of hCD59 in porcine organs provides protection against hyperacute rejection.

Development of a Model for Chemical Screening Based on Collateral Sensitivity to Target BTK C481S Mutant

Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing

Editorial: Gene Therapy for Fanconi Anemia Enters a New Clinical Era.

Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector

Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors.

Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide.

Efficient transduction of healthy and malignant plasma cells by lentiviral vectors pseudotyped with measles virus glycoproteins ⬇️

Engineering of α-PD-1 antibody-expressing long-lived plasma cells by CRISPR/Cas9-mediated targeted gene integration

Engineering the surface glycoproteins of lentiviral vectors for targeted gene transfer

Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

Epigenetic silencing and tissue independent expression of a novel tetracycline inducible system in double-transgenic pigs.

Epitope dampening monotypic measles virus hemagglutinin glycoprotein results in resistance to cocktail of monoclonal antibodies.

Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists.

Erratum: Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

Evaluation of retroviral vector design in defined chromosomal loci by Flp-mediated cassette replacement.

Exclusive Transduction of Human CD4+ T Cells upon Systemic Delivery of CD4-Targeted Lentiviral Vectors

GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors

GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism

GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-κB-dependent induction of HIF-1α.

Gene Therapy in Fanconi anemia: a matter of time, safety and gene transfer tool efficiency

Gene therapy for Fanconi anemia: one step closer to the clinic.

Gene-corrected human Munc13-4-deficient CD8+ T cells can efficiently restrict EBV-driven lymphoproliferation in immunodeficient mice.

Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.

Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

Glut1-mediated glucose transport regulates HIV infection

HSP110 sustains chronic NF-κB signaling in activated B-cell diffuse large B-cell lymphoma through MyD88 stabilization

Haploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms

Hematopoietic stem cell targeting with surface-engineered lentiviral vectors.

High SYK Expression Drives Constitutive Activation of CD21low B Cells.

High levels of SOX5 decrease proliferative capacity of human B cells, but permit plasmablast differentiation.

Human monocyte recognition of adenosine-based cyclic dinucleotides unveils the A2a Gαs protein-coupled receptor tonic inhibition of mitochondrially induced cell death

Humanized Mice Are Precious Tools for Preclinical Evaluation of CAR T and CAR NK Cell Therapies

Humanized mice are precious tools for evaluation of hematopoietic gene therapies and preclinical modeling to move towards a clinical trial

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.

IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes

IL-7R alpha gene expression is inversely correlated with cell cycle progression in IL-7-stimulated T lymphocytes

Importance of T, NK, CAR T and CAR NK Cell Metabolic Fitness for Effective Anti-Cancer Therapy: A Continuous Learning Process Allowing the Optimization of T, NK and CAR-Based Anti-Cancer Therapies

Improved lentiviral vectors for Wiskott-Aldrich syndrome gene therapy mimic endogenous expression profiles throughout haematopoiesis.

In vivo gene delivery into hCD34+ cells in a humanized mouse model

Lentiviral vector gene transfer into human T cells.

Lentiviral vectors

Lentiviral vectors and transduction of human cancer B cells.

Lentiviral vectors displaying modified measles virus gp overcome pre-existing immunity in in vivo-like transduction of human T and B cells.

Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics

Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance.

Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent

Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent lymphocytes requires binding to both SLAM and CD46 entry receptors.

Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis

Multiplex CRISPR/Cas9 system impairs HCMV replication by excising an essential viral gene.

Mutations in the H, F, or M Proteins Can Facilitate Resistance of Measles Virus to Neutralizing Human Anti-MV Sera.

Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.

Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.

New approaches towards ex vivo and in vivo gene therapy

New preclinical models for angioimmunoblastic T-cell lymphoma: filling the GAP