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Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease

scientific article published on 01 July 2019

Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death

artículo científico publicado en 2003

Caspase-6 activity in a BACHD mouse modulates steady-state levels of mutant huntingtin protein but is not necessary for production of a 586 amino acid proteolytic fragment.

artículo científico publicado en 2012

Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.

artículo científico publicado en 2012

Diffusion tensor MRI with tract-based spatial statistics and histology reveals undiscovered lesioned areas in kainate model of epilepsy in rat

artículo científico publicado en 2011

Effect of Ibuprofen on Skeletal Muscle of Dysferlin-null Mice.

artículo científico publicado en 2017

Genetic deletion of transglutaminase 2 does not rescue the phenotypic deficits observed in R6/2 and zQ175 mouse models of Huntington's disease.

artículo científico publicado en 2014

High-resolution magic-angle-spinning 1H NMR spectroscopy reveals different responses in choline-containing metabolites upon gene therapy-induced programmed cell death in rat brain glioma.

artículo científico publicado en 2005

Hip region muscular dystrophy and emergence of motor deficits in dysferlin-deficient Bla/J mice

artículo científico publicado en 2017

Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.

artículo científico publicado en 2003

Multimodal MRI assessment of damage and plasticity caused by status epilepticus in the rat brain.

artículo científico publicado en 2011

Novel magnetic resonance imaging contrasts for monitoring response to gene therapy in rat glioma

artículo científico publicado en 2003

Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington's Disease Models.

artículo científico publicado en 2016

Progressive volume loss and white matter degeneration in cstb-deficient mice: a diffusion tensor and longitudinal volumetry MRI study

artículo científico publicado en 2014

Stem cell profiling by nuclear magnetic resonance spectroscopy.

artículo científico publicado en 2006

Systemic Delivery of Dysferlin Overlap Vectors Provides Long-Term Gene Expression and Functional Improvement for Dysferlinopathy

artículo científico

The PDE1/5 Inhibitor SCH-51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's Disease

artículo científico publicado en 2014

The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain.

artículo científico publicado en 2017

The novel KMO inhibitor CHDI-340246 leads to a restoration of electrophysiological alterations in mouse models of Huntington's disease.

artículo científico publicado en 2016

Water diffusion in a rat glioma during ganciclovir-thymidine kinase gene therapy-induced programmed cell death in vivo: correlation with cell density.

artículo científico publicado en 2004

mNos2 deletion and human NOS2 replacement in Alzheimer disease models

artículo científico publicado en 2014