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A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism

artículo científico publicado en 2017

Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.

artículo científico publicado en 2001

FIH-dependent asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.

scientific article published on October 2009

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

artículo científico publicado en 2011

Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy

artículo científico publicado en 2014

In vitro transcription and translation of the tumour suppressor protein P53: qualitative and quantitative effects of FK506 and rapamycin

artículo científico publicado en 1998

Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin

scientific article published on 14 November 2018

Interaction of hydroxylated collagen IV with the von hippel-lindau tumor suppressor.

artículo científico publicado en 2007

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates

scientific article published on 10 September 2019

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

artículo científico publicado en 2014

Optimal translational termination requires C4 lysyl hydroxylation of eRF1.

scientific article published on 30 January 2014

Oxygen sensing

scientific article published on 01 January 2005

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

artículo científico publicado en 2012

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

artículo científico publicado en 2006

Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.

artículo científico publicado en 2008

Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

artículo científico publicado en 2018

Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation.

artículo científico publicado en 2011

Selection of mutant CHO cells with constitutive activation of the HIF system and inactivation of the von Hippel-Lindau tumor suppressor

artículo científico publicado en 2001

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

artículo científico publicado en 2019

Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth.

artículo científico publicado en 2014

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

article

The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma

artículo científico publicado en 2007

Wild-type p53 protein shows calcium-dependent binding to F-actin

artículo científico publicado en 1999