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5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice.

artículo científico publicado en 2018

CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages

artículo científico publicado en 2021

Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.

artículo científico publicado en 2007

Expression and localization of rat aldo-keto reductases and induction of the 1B13 and 1D2 isoforms by phenolic antioxidants.

artículo científico publicado en 2009

Expression of rat aldehyde reductase AKR7A1: influence of age and sex and tissue-specific inducibility.

artículo científico publicado en 2001

Heterozygous disruption of ALAS1 in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver

scientific article published on 08 December 2020

High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress.

artículo científico publicado en 2002

Highly efficient CRISPR-targeting of the murine Hipp11 intergenic region supports inducible human transgene expression

scientific article published on 06 December 2019

Malonylation of GAPDH is an inflammatory signal in macrophages

artículo científico publicado en 2019

Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia

scientific journal article

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

artículo científico publicado en 2018

Purification from rat liver of a novel constitutively expressed member of the aldo-keto reductase 7 family that is widely distributed in extrahepatic tissues.

artículo científico publicado en 2000

Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells

scientific article published on 24 March 2020

Queuine links translational control in eukaryotes to a micronutrient from bacteria

artículo científico publicado en 2019

Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidation

artículo científico publicado en 2011

Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase

scientific journal article

TRMT2A is a novel cell cycle regulator that suppresses cell proliferation

artículo científico publicado en 2018

The "speed gene" effect of myostatin arises in Thoroughbred horses due to a promoter proximal SINE insertion

artículo científico publicado en 2018

The distal sequence element of the selenocysteine tRNA gene is a tissue-dependent enhancer essential for mouse embryogenesis

artículo científico publicado en 2005

The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity

artículo científico publicado en 2021

The queuine micronutrient: charting a course from microbe to man.

artículo científico publicado en 2015

The study using wild-type and Ogg1 knockout mice exposed to potassium bromate shows no tumor induction despite an extensive accumulation of 8-hydroxyguanine in kidney DNA.

artículo científico publicado en 2006

Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2)

artículo científico publicado en 2004

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