Lista de obras - Ronald Duman - Dominio Público Uruguay

A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis

scientific journal article

Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects ⬇️

artículo científico publicado el 17 de febrero de 2012

Antidepressant Effects of Fibroblast Growth Factor-2 in Behavioral and Cellular Models of Depression ⬇️

artículo científico publicado el 17 de abril de 2012

Antidepressant effect of the calcium-activated tyrosine kinase Pyk2 in the lateral septum

scientific journal article

Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection

artículo científico publicado en 2008

Antipsychotic-induced gene regulation in multiple brain regions

artículo científico publicado en 2010

Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex ⬇️

artículo científico publicado el 29 de octubre de 2011

Cell atrophy and loss in depression: reversal by antidepressant treatment ⬇️

artículo científico publicado el 11 de octubre de 2011

Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment

artículo científico publicado en 2003

Cell-type specific modulation of NMDA receptors triggers antidepressant actions

artículo científico publicado en 2020

Chromatin remodeling: a novel mechanism of psychotropic drug action

artículo científico publicado en 2006

Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat.

artículo científico publicado en 2004

Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress

artículo científico publicado en 2015

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

scientific journal article

Depression: a case of neuronal life and death?

artículo científico publicado en 2004

Differential expression and regulation of the cAMP-selective phosphodiesterase type 4A splice variants in rat brain by chronic antidepressant administration

scientific journal article

Effects of estradiol on learned helplessness and associated remodeling of hippocampal spine synapses in female rats.

scientific article published on January 2010

Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder

artículo científico publicado en 2008

Electroconvulsive seizure-induced gene expression profile of the hippocampus dentate gyrus granule cell layer

artículo científico publicado en 2006

Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity

artículo científico publicado en 2016

Epigenome-wide association study of posttraumatic stress disorder identifies novel loci in U.S. military veterans

artículo científico publicado en 2022

GABA interneurons mediate the rapid antidepressant-like effects of scopolamine

artículo científico publicado en 2016

GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine.

artículo científico publicado en 2016

GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine

artículo científico publicado en 2013

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure ⬇️

artículo científico publicado el 3 de febrero de 2011

Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment

artículo científico publicado en 2006

How do antidepressants work? New perspectives for refining future treatment approaches.

artículo científico publicado en 2017

Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses

artículo científico publicado en 2020

Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect.

artículo científico publicado en 2002

Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation

scientific article published on 11 March 2020

It is time to take a stand for medical research and against terrorism targeting medical scientists

artículo científico publicado en 2008

Ketamine Strengthens CRF-Activated Amygdala Inputs to Basal Dendrites in mPFC Layer V Pyramidal Cells in the Prelimbic but not Infralimbic Subregion, A Key Suppressor of Stress Responses

artículo científico publicado en 2015

Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide.

artículo científico publicado en 2018

Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics

artículo científico publicado en 2014

Ketamine: A Paradigm Shift for Depression Research and Treatment

scientific article published on 01 March 2019

Medial PFC AMPA receptor and BDNF signaling are required for the rapid and sustained antidepressant-like effects of 5-HT1A receptor stimulation

artículo científico publicado en 2020

Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin

artículo científico publicado en 2020

Molecular and cellular studies of PTSD: Postmortem transcriptome analysis and novel therapeutic targets

scientific article published on 23 August 2018

Neurobiology of rapid acting antidepressants: role of BDNF and GSK-3β.

artículo científico publicado en 2014

Neurogenic actions of atypical antipsychotic drugs and therapeutic implications

artículo científico publicado en 2007

Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior

artículo científico publicado en 2010

Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions.

artículo científico publicado en 2015

Overexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats

artículo científico publicado en 2014

PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies

scientific article published on 12 May 2020

Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections

artículo científico publicado en 2014

Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models

artículo científico publicado en 2010

Positive modulation of NMDA receptors by AGN-241751 exerts rapid antidepressant-like effects via excitatory neurons

artículo científico publicado en 2020

Post-weaning chronic social isolation produces profound behavioral dysregulation with decreases in prefrontal cortex synaptic-associated protein expression in female rats

artículo científico publicado en 2010

Prefrontal cortex circuits in depression and anxiety: contribution of discrete neuronal populations and target regions

scientific article published on 21 February 2020

REDD1 is essential for stress-induced synaptic loss and depressive behavior

artículo científico publicado en 2014

Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors

artículo científico publicado en 2015

Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond

artículo científico publicado en 2013

Regulation of neurogenesis and angiogenesis in depression

artículo científico publicado en 2004

Remodeling of hippocampal spine synapses in the rat learned helplessness model of depression

artículo científico publicado en 2008

Repeated unpredictable stress and antidepressants differentially regulate expression of the bcl-2 family of apoptotic genes in rat cortical, hippocampal, and limbic brain structures

scientific journal article

Role of BDNF in the pathophysiology and treatment of depression: Activity-dependent effects distinguish rapid-acting antidepressants

scientific article published on 06 December 2019

Role of neurotrophic factors in the etiology and treatment of mood disorders

artículo científico publicado en 2004

Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses.

artículo científico publicado en 2013

Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications

artículo científico publicado en 2008

Signaling pathways underlying the rapid antidepressant actions of ketamine ⬇️

artículo científico publicado el 2 de septiembre de 2011

Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects

artículo científico publicado en 2004

Stress induces equivalent remodeling of hippocampal spine synapses in a simulated postpartum environment and in a female rat model of major depression

artículo científico publicado en 2016

Synaptic Dysfunction in Depression: Potential Therapeutic Targets ⬇️

artículo científico publicado el 5 de octubre de 2012

Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic.

artículo científico publicado en 2017

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

artículo científico publicado en 2016

Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome

artículo científico publicado en 2015

The Connecticut Mental Health Center: Celebrating 50 Years of a Successful Partnership Between the State and Yale University

artículo científico publicado en 2016

The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?

scientific article published on 25 May 2018

The stress-induced transcription factor NR4A1 adjusts mitochondrial function and synapse number in prefrontal cortex.

artículo científico publicado en 2018

Transcriptomic organization of the human brain in post-traumatic stress disorder

scientific article published on 21 December 2020

VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants

scientific journal article

Wnt2 expression and signaling is increased by different classes of antidepressant treatments

artículo científico publicado en 2010

mGluR2/3 blockade produces rapid and long-lasting reversal of anhedonia caused by chronic stress exposure

artículo científico publicado en 2013

mTOR activation is required for the antidepressant effects of mGluR2/3 blockade ⬇️

artículo científico publicado el 24 de noviembre de 2011

mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

artículo científico publicado en 2010

Lista de obras de Ronald Duman

A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis

Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects ⬇️

Antidepressant Effects of Fibroblast Growth Factor-2 in Behavioral and Cellular Models of Depression ⬇️

Antidepressant effect of the calcium-activated tyrosine kinase Pyk2 in the lateral septum

Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection

Antipsychotic-induced gene regulation in multiple brain regions

Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex ⬇️

Cell atrophy and loss in depression: reversal by antidepressant treatment ⬇️

Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment

Cell-type specific modulation of NMDA receptors triggers antidepressant actions

Chromatin remodeling: a novel mechanism of psychotropic drug action

Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat.

Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

Depression: a case of neuronal life and death?

Differential expression and regulation of the cAMP-selective phosphodiesterase type 4A splice variants in rat brain by chronic antidepressant administration

Effects of estradiol on learned helplessness and associated remodeling of hippocampal spine synapses in female rats.

Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder

Electroconvulsive seizure-induced gene expression profile of the hippocampus dentate gyrus granule cell layer

Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity

Epigenome-wide association study of posttraumatic stress disorder identifies novel loci in U.S. military veterans

GABA interneurons mediate the rapid antidepressant-like effects of scopolamine

GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine.

GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure ⬇️

Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment

How do antidepressants work? New perspectives for refining future treatment approaches.

Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses

Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect.

Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation

It is time to take a stand for medical research and against terrorism targeting medical scientists

Ketamine Strengthens CRF-Activated Amygdala Inputs to Basal Dendrites in mPFC Layer V Pyramidal Cells in the Prelimbic but not Infralimbic Subregion, A Key Suppressor of Stress Responses

Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide.

Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics

Ketamine: A Paradigm Shift for Depression Research and Treatment

Medial PFC AMPA receptor and BDNF signaling are required for the rapid and sustained antidepressant-like effects of 5-HT1A receptor stimulation

Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin

Molecular and cellular studies of PTSD: Postmortem transcriptome analysis and novel therapeutic targets

Neurobiology of rapid acting antidepressants: role of BDNF and GSK-3β.

Neurogenic actions of atypical antipsychotic drugs and therapeutic implications

Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior

Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions.

Overexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats

PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies

Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections

Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models

Positive modulation of NMDA receptors by AGN-241751 exerts rapid antidepressant-like effects via excitatory neurons

Post-weaning chronic social isolation produces profound behavioral dysregulation with decreases in prefrontal cortex synaptic-associated protein expression in female rats

Prefrontal cortex circuits in depression and anxiety: contribution of discrete neuronal populations and target regions

REDD1 is essential for stress-induced synaptic loss and depressive behavior

Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors

Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond

Regulation of neurogenesis and angiogenesis in depression

Remodeling of hippocampal spine synapses in the rat learned helplessness model of depression

Repeated unpredictable stress and antidepressants differentially regulate expression of the bcl-2 family of apoptotic genes in rat cortical, hippocampal, and limbic brain structures

Role of BDNF in the pathophysiology and treatment of depression: Activity-dependent effects distinguish rapid-acting antidepressants

Role of neurotrophic factors in the etiology and treatment of mood disorders

Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses.

Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications

Signaling pathways underlying the rapid antidepressant actions of ketamine ⬇️

Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects

Stress induces equivalent remodeling of hippocampal spine synapses in a simulated postpartum environment and in a female rat model of major depression

Synaptic Dysfunction in Depression: Potential Therapeutic Targets ⬇️

Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic.

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome

The Connecticut Mental Health Center: Celebrating 50 Years of a Successful Partnership Between the State and Yale University

The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?

The stress-induced transcription factor NR4A1 adjusts mitochondrial function and synapse number in prefrontal cortex.

Transcriptomic organization of the human brain in post-traumatic stress disorder

VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants

Wnt2 expression and signaling is increased by different classes of antidepressant treatments

mGluR2/3 blockade produces rapid and long-lasting reversal of anhedonia caused by chronic stress exposure

mTOR activation is required for the antidepressant effects of mGluR2/3 blockade ⬇️

mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists