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Activity of the MEK inhibitor selumetinib (AZD6244; ARRY-142886) in nasopharyngeal cancer cell lines.

artículo científico publicado en 2012

An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-beta-d-ribo-pentofuranosyl)cytosine (ECyd), elicits antitumor effect via TP53-induced Glycolysis and Apoptosis Regulator (TIGAR) downregulation.

artículo científico publicado en 2010

An update of ALK inhibitors in human clinical trials.

artículo científico publicado en 2015

An update on genomic-guided therapies for pediatric solid tumors.

artículo científico

Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells.

artículo científico publicado en 2010

Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1.

artículo científico publicado en 2007

Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma.

artículo científico publicado en 2014

Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts

artículo científico publicado en 2013

Blockade of PD-1 effectively inhibits in vivo malignant transformation of oral mucosa

artículo científico publicado en 2017

Cancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air pollution.

artículo científico publicado en 2014

Case Report: Exome sequencing reveals recurrent RETSAT mutations and a loss-of-function POLDIP2 mutation in a rare undifferentiated tongue sarcoma.

artículo científico publicado en 2018

Comprehensive Exome Analysis of Immunocompetent Metastatic Head and Neck Cancer Models Reveals Patient Relevant Landscapes

artículo científico publicado en 2020

Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells.

artículo científico publicado en 2009

Effects of Salivary Mg on Head and Neck Carcinoma via TRPM7

scientific article published on 04 December 2018

Erlotinib sensitivity of MAPK1p.D321N mutation in head and neck squamous cell carcinoma

artículo científico publicado en 2020

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations

artículo científico publicado en 2017

Full-length Mst1 exhibits growth promoting function in human hepatocellular carcinoma cells.

artículo científico publicado en 2013

Genetic landscape of metastatic and recurrent head and neck squamous cell carcinoma.

artículo científico publicado en 2015

Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck Cancer

artículo científico publicado en 2018

Genomic analysis of head and neck squamous cell carcinoma cell lines and human tumors: a rational approach to preclinical model selection.

artículo científico publicado en 2014

Genomic profiles of nasopharyngeal carcinoma: The importance of histological subtyping and Epstein-Barr virus in situ assays.

artículo científico publicado en 2017

Germline mutation and aberrant transcripts of WWOX in a syndrome with multiple primary tumors

artículo científico publicado en 2019

Hypermethylation of NF-κB-Activating Protein-Like (NKAPL) Promoter in Hepatocellular Carcinoma Suppresses Its Expression and Predicts a Poor Prognosis.

artículo científico publicado en 2018

Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation.

artículo científico publicado en 2009

Identification of mutations in the PYRIN-containing NLR genes (NLRP) in Head and Neck Squamous Cell Carcinoma.

scientific article published on 21 January 2014

Inactivation of ATP citrate lyase by Cucurbitacin B: A bioactive compound from cucumber, inhibits prostate cancer growth.

artículo científico publicado en 2014

Induction of laryngeal cancer cell death by Ent-11-hydroxy-15-oxo-kaur-16-en-19-oic acid.

artículo científico publicado en 2010

JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.

artículo científico publicado en 2015

K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr virus (EBV)--associated nasopharyngeal carcinoma cells.

artículo científico publicado en 2010

Loss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck Cancer

artículo científico publicado en 2015

MAPK pathway mutations in head and neck cancer affect immune microenvironments and ErbB3 signaling

scientific article published on 07 May 2020

Mesenchymal stem cells participate in oral mucosa carcinogenesis by regulating T cell proliferation

artículo científico publicado en 2018

Microneedle-Mediated Delivery of Lipid-Coated Cisplatin Nanoparticles for Efficient and Safe Cancer Therapy

scientific article published on 24 September 2018

PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma.

artículo científico publicado en 2013

Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation.

artículo científico publicado en 2006

Preclinical evaluation of combined TKI-258 and RAD001 in hepatocellular carcinoma.

artículo científico publicado en 2013

Preclinical evaluation of sunitinib as single agent or in combination with chemotherapy in nasopharyngeal carcinoma.

artículo científico publicado en 2010

Preclinical evaluation of the mTOR-PI3K inhibitor BEZ235 in nasopharyngeal cancer models.

artículo científico publicado en 2013

Prediction of radiotherapy response with a 5-microRNA signature-based nomogram in head and neck squamous cell carcinoma.

artículo científico publicado en 2018

Primary chemotherapy and radiation as a treatment strategy for HPV-positive oropharyngeal cancer

artículo científico publicado en 2012

Prognostic significance of tumor infiltrating immune cells in oral squamous cell carcinoma

artículo científico publicado en 2017

Proteomic Characterization of Head and Neck Cancer Patient-Derived Xenografts

artículo científico publicado en 2015

Quantitative proteomics analysis reveals molecular networks regulated by epidermal growth factor receptor level in head and neck cancer.

artículo científico publicado en 2010

Requirement of a carbon spacer in benzyl isothiocyanate-mediated cytotoxicity and MAPK activation in head and neck squamous cell carcinoma.

artículo científico publicado en 2003

Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1.

artículo científico publicado en 2009

STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro.

artículo científico publicado en 2009

Sodium chloride (NaCl) potentiates digoxin-induced anti-tumor activity in small cell lung cancer

artículo científico publicado en 2018

Specific down-regulation of HER-2/neu mediated by a chimeric U6 hammerhead ribozyme results in growth inhibition of human ovarian carcinoma.

artículo científico publicado en 2001

Stromal interleukin-33 promotes regulatory T cell-mediated immunosuppression in head and neck squamous cell carcinoma and correlates with poor prognosis

artículo científico publicado en 2018

Sustained antitumor activity by co-targeting mTOR and the microtubule with temsirolimus/vinblastine combination in hepatocellular carcinoma.

artículo científico publicado en 2012

Systemic administration of naked DNA encoding interleukin 12 for the treatment of human papillomavirus DNA-positive tumor.

artículo científico publicado en 2002

TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression.

artículo científico publicado en 2012

TP53-induced glycolysis and apoptosis regulator promotes proliferation and invasiveness of nasopharyngeal carcinoma cells.

artículo científico publicado en 2014

Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.

artículo científico publicado en 2011

Targeting tumor hypoxia in nasopharyngeal carcinoma.

artículo científico publicado en 2011

The Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma.

artículo científico publicado en 2013

The Intersection between Oral Microbiota, Host Gene Methylation and Patient Outcomes in Head and Neck Squamous Cell Carcinoma

artículo científico publicado en 2020

The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.

artículo científico publicado en 2017

Thrombomodulin (TM) in tumor cell differentiation and periphery blood immune microenvironment in oral squamous cell carcinoma

artículo científico publicado en 2018

miR-466 is putative negative regulator of Coxsackie virus and Adenovirus Receptor

artículo científico publicado en 2014