Lista de obras -

A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.

artículo científico publicado en 2010

A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity

scientific article published on 31 January 2019

A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype

artículo científico publicado en 2010

Amyloid-beta precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress.

artículo científico publicado en 2007

An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation

artículo científico publicado en 2019

Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation.

artículo científico publicado en 2018

Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53.

artículo científico publicado en 2001

DNA-damage response in hematopoietic stem cells: an evolutionary trade-off between blood regeneration and leukemia suppression.

artículo científico publicado en 2017

Erratum: Replication stress in MLL-rearrangements.

artículo científico publicado en 2016

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells

artículo científico publicado en 2011

Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.

artículo científico publicado en 2003

Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.

artículo científico publicado en 2007

Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells

artículo científico publicado en 2020

Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling

artículo científico publicado en 2013

Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate-induced death by attenuating activating transcription factor 3 induction

artículo científico publicado en 2006

Myocardin in tumor suppression and myofibroblast differentiation.

artículo científico publicado en 2007

Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.

artículo científico publicado en 2003

Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.

artículo científico publicado en 2016

Replication stress in MLL-rearrangements

artículo científico publicado en 2015

Replication stress in hematopoietic stem cells in mouse and man.

artículo científico publicado en 2017

SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress

artículo científico publicado en 2017

Spironolactone inhibits the growth of cancer stem cells by impairing DNA damage response

scientific article published on 08 January 2019

The murine telomerase catalytic subunit shares the PAb-240 mutant specific epitope of the p53 protein.

artículo científico publicado en 2003

The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA.

artículo científico publicado en 2002

The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation.

artículo científico publicado en 2005

The role of the C' terminus of murine p53 in the p53/mdm-2 regulatory loop.

artículo científico publicado en 2001

Transcriptional programs following genetic alterations in p53, INK4A, and H-Ras genes along defined stages of malignant transformation

artículo científico publicado en 2005

Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.

artículo científico publicado en 2009

hTERT-immortalized prostate epithelial and stromal-derived cells: an authentic in vitro model for differentiation and carcinogenesis

artículo científico publicado en 2006

p53 is a regulator of macrophage differentiation.

artículo científico publicado en 2004

p53 mediates density-dependent growth arrest.

artículo científico publicado en 2004

p53 modulates base excision repair activity in a cell cycle-specific manner after genotoxic stress.

artículo científico publicado en 2001

p53-dependent down-regulation of telomerase is mediated by p21waf1.

artículo científico publicado en 2004

Lista de obras de

A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.

A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity

A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype

Amyloid-beta precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress.

An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation

Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation.

Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53.

DNA-damage response in hematopoietic stem cells: an evolutionary trade-off between blood regeneration and leukemia suppression.

Erratum: Replication stress in MLL-rearrangements.

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells

Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.

Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.

Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells

Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling

Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate-induced death by attenuating activating transcription factor 3 induction

Myocardin in tumor suppression and myofibroblast differentiation.

Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.

Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.

Replication stress in MLL-rearrangements

Replication stress in hematopoietic stem cells in mouse and man.

SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress

Spironolactone inhibits the growth of cancer stem cells by impairing DNA damage response

The murine telomerase catalytic subunit shares the PAb-240 mutant specific epitope of the p53 protein.

The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA.

The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation.

The role of the C' terminus of murine p53 in the p53/mdm-2 regulatory loop.

Transcriptional programs following genetic alterations in p53, INK4A, and H-Ras genes along defined stages of malignant transformation

Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.

hTERT-immortalized prostate epithelial and stromal-derived cells: an authentic in vitro model for differentiation and carcinogenesis

p53 is a regulator of macrophage differentiation.

p53 mediates density-dependent growth arrest.

p53 modulates base excision repair activity in a cell cycle-specific manner after genotoxic stress.

p53-dependent down-regulation of telomerase is mediated by p21waf1.