Lista de obras -

5-alpha-reductase type I (SRD5A1) is up-regulated in non-small cell lung cancer but does not impact proliferation, cell cycle distribution or apoptosis.

artículo científico publicado en 2012

Alzheimer amyloid peptide aβ42 regulates gene expression of transcription and growth factors

artículo científico publicado en 2015

Androgen receptor and prostate cancer: molecular aspects and gene expression profiling

artículo científico publicado el 1 de septiembre de 2003

Antibody-Drug Conjugates with Pyrrole-Based KSP Inhibitors as the Payload Class

artículo científico publicado en 2018

Antibody-Prodrug Conjugates with KSP Inhibitors and Legumain-Mediated Metabolite Formation

artículo científico publicado en 2019

Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation

artículo científico publicado en 2012

Aspects of lung cancer gene expression profiling.

artículo científico publicado en 2004

Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity

artículo científico publicado en 1997

Comparison of proteomic and genomic analyses of the human breast cancer cell line T47D and the antiestrogen-resistant derivative T47D-r.

artículo científico publicado en 2003

DNA binding by estrogen receptor-alpha is essential for the transcriptional response to estrogen in the liver and the uterus

artículo científico publicado en 2009

Efficacy of MS-275, a selective inhibitor of class I histone deacetylases, in human colon cancer models.

artículo científico publicado en 2009

Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.

artículo científico publicado en 2008

Evaluation of activity and combination strategies with the microtubule-targeting drug sagopilone in breast cancer cell lines.

artículo científico publicado en 2011

Exon Array Analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer ⬇️

artículo científico publicado el 30 de noviembre de 2010

First-in-Human Phase I Study of Aprutumab Ixadotin, a Fibroblast Growth Factor Receptor 2 Antibody-Drug Conjugate (BAY 1187982) in Patients with Advanced Cancer

artículo científico publicado en 2019

Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system.

artículo científico publicado en 2008

HDAC11 is a novel drug target in carcinomas.

artículo científico publicado en 2012

HMGA proteins regulate the expression of FGF2 in uterine fibroids ⬇️

artículo científico publicado el 6 de octubre de 2010

IL3RA-Targeting Antibody-Drug Conjugate BAY-943 with a Kinesin Spindle Protein Inhibitor Payload Shows Efficacy in Preclinical Models of Hematologic Malignancies

artículo científico publicado en 2020

Identification and characterization of specific DNA-binding complexes containing members of the Myc/Max/Mad network of transcriptional regulators

scientific article published on 01 March 1998

In vivo models for endocrine-dependent breast carcinomas: special considerations of clinical relevance.

artículo científico publicado en 2004

Isogenic human mammary epithelial cell lines: novel tools for target identification and validation. Comprehensive characterization of an isogenic human mammary epithelial cell model provides evidence for epithelial-mesenchymal transition.

artículo científico publicado en 2013

Knockdown of platinum-induced growth differentiation factor 15 abrogates p27-mediated tumor growth delay in the chemoresistant ovarian cancer model A2780cis

artículo científico publicado en 2014

Molecular Mode of Action and Role of TP53 in the Sensitivity to the Novel Epothilone Sagopilone (ZK-EPO) in A549 Non-Small Cell Lung Cancer Cells ⬇️

artículo científico publicado el 29 de abril de 2011

Molecular profiles and clinical outcome of stage UICC II colon cancer patients

scientific article published on 05 April 2011

Novel molecular aspects of prostate carcinogenesis.

artículo científico publicado en 2004

Preclinical Combination Studies of an FGFR2 Targeted Thorium-227 Conjugate and the ATR Inhibitor BAY 1895344

scientific article published on 27 June 2019

Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors.

artículo científico publicado en 2016

Regulation of cell growth by the Myc-Max-Mad network: role of Mad proteins and YY1.

artículo científico publicado en 1997

Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors.

artículo científico publicado en 2001

Steroid hormone receptors as targets for the therapy of breast and prostate cancer--recent advances, mechanisms of resistance, and new approaches.

artículo científico publicado en 2005

Studies on the development of resistance to the pure antiestrogen Faslodex in three human breast cancer cell lines.

artículo científico publicado en 2003

Synergistic activation of the mkp-1 gene by protein kinase A signaling and USF, but not c-Myc

article

What makes a good drug target?

artículo científico

What makes a good drug target?

scientific article published on 11 December 2011

Lista de obras de

5-alpha-reductase type I (SRD5A1) is up-regulated in non-small cell lung cancer but does not impact proliferation, cell cycle distribution or apoptosis.

Alzheimer amyloid peptide aβ42 regulates gene expression of transcription and growth factors

Androgen receptor and prostate cancer: molecular aspects and gene expression profiling

Antibody-Drug Conjugates with Pyrrole-Based KSP Inhibitors as the Payload Class

Antibody-Prodrug Conjugates with KSP Inhibitors and Legumain-Mediated Metabolite Formation

Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation

Aspects of lung cancer gene expression profiling.

Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity

Comparison of proteomic and genomic analyses of the human breast cancer cell line T47D and the antiestrogen-resistant derivative T47D-r.

DNA binding by estrogen receptor-alpha is essential for the transcriptional response to estrogen in the liver and the uterus

Efficacy of MS-275, a selective inhibitor of class I histone deacetylases, in human colon cancer models.

Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.

Evaluation of activity and combination strategies with the microtubule-targeting drug sagopilone in breast cancer cell lines.

Exon Array Analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer ⬇️

First-in-Human Phase I Study of Aprutumab Ixadotin, a Fibroblast Growth Factor Receptor 2 Antibody-Drug Conjugate (BAY 1187982) in Patients with Advanced Cancer

Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system.

HDAC11 is a novel drug target in carcinomas.

HMGA proteins regulate the expression of FGF2 in uterine fibroids ⬇️

IL3RA-Targeting Antibody-Drug Conjugate BAY-943 with a Kinesin Spindle Protein Inhibitor Payload Shows Efficacy in Preclinical Models of Hematologic Malignancies

Identification and characterization of specific DNA-binding complexes containing members of the Myc/Max/Mad network of transcriptional regulators

In vivo models for endocrine-dependent breast carcinomas: special considerations of clinical relevance.

Isogenic human mammary epithelial cell lines: novel tools for target identification and validation. Comprehensive characterization of an isogenic human mammary epithelial cell model provides evidence for epithelial-mesenchymal transition.

Knockdown of platinum-induced growth differentiation factor 15 abrogates p27-mediated tumor growth delay in the chemoresistant ovarian cancer model A2780cis

Molecular Mode of Action and Role of TP53 in the Sensitivity to the Novel Epothilone Sagopilone (ZK-EPO) in A549 Non-Small Cell Lung Cancer Cells ⬇️

Molecular profiles and clinical outcome of stage UICC II colon cancer patients

Novel molecular aspects of prostate carcinogenesis.

Preclinical Combination Studies of an FGFR2 Targeted Thorium-227 Conjugate and the ATR Inhibitor BAY 1895344

Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors.

Regulation of cell growth by the Myc-Max-Mad network: role of Mad proteins and YY1.

Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors.

Steroid hormone receptors as targets for the therapy of breast and prostate cancer--recent advances, mechanisms of resistance, and new approaches.

Studies on the development of resistance to the pure antiestrogen Faslodex in three human breast cancer cell lines.

Synergistic activation of the mkp-1 gene by protein kinase A signaling and USF, but not c-Myc

What makes a good drug target?

What makes a good drug target?