Lista de obras -

A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides.

artículo científico publicado en 2010

African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infection.

artículo científico publicado en 2007

African swine fever virus p37 structural protein is localized in nuclear foci containing the viral DNA at early post-infection times.

artículo científico publicado en 2007

Anticancer activity and antibody-dependent cell-mediated cytotoxicity of novel anti-nucleolin antibodies.

artículo científico publicado en 2018

Association of albumin or protamine to lipoplexes: enhancement of transfection and resistance to serum.

artículo científico publicado en 2004

Biodistribution and photodynamic efficacy of a water-soluble, stable, halogenated bacteriochlorin against melanoma.

artículo científico publicado en 2011

Biophysical characterization of cationic liposome-DNA complexes and their interaction with cells.

artículo científico publicado en 2003

Cationic lipid-DNA complexes in gene delivery: from biophysics to biological applications.

artículo científico publicado en 2001

Cationic liposome-DNA complexes as gene delivery vectors: Development and behaviour towards bone-like cells.

artículo científico publicado en 2009

Cellular and molecular events associated with the antitumor response induced by the cytosine deaminase/5-fluorocytosine suicide gene therapy system in a rat liver metastasis model.

artículo científico publicado en 2007

Cellular uptake of S4 13 -PV peptide occurs upon conformational changes induced by peptide–membrane interactions

artículo científico publicado en 2006

Challenging the future of siRNA therapeutics against cancer: the crucial role of nanotechnology

artículo científico publicado en 2013

Ciprofloxacin sensitizes hormone-refractory prostate cancer cell lines to doxorubicin and docetaxel treatment on a schedule-dependent manner.

artículo científico publicado en 2008

Co-encapsulation of anti-BCR-ABL siRNA and imatinib mesylate in transferrin receptor-targeted sterically stabilized liposomes for chronic myeloid leukemia treatment.

artículo científico publicado en 2010

Combined effects of singlet oxygen and hydroxyl radical in photodynamic therapy with photostable bacteriochlorins: Evidence from intracellular fluorescence and increased photodynamic efficacy in vitro

scientific article published on 14 January 2012

DNA pre-condensation with an amino acid-based cationic amphiphile. A viable approach for liposome-based gene delivery.

artículo científico publicado en 2008

Delivery of antiviral agents in liposomes.

artículo científico publicado en 2005

Development, characterization and in vitro evaluation of single or co-loaded imatinib mesylate liposomal formulations.

artículo científico publicado en 2012

Enhanced inhibition of HIV-1 replication in macrophages by antisense oligonucleotides, ribozymes and acyclic nucleoside phosphonate analogs delivered in pH-sensitive liposomes.

artículo científico publicado en 2001

Gene delivery by cationic liposome-DNA complexes containing transferrin or serum albumin.

artículo científico publicado en 2003

Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusigenic peptides.

artículo científico publicado en 1998

Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum.

artículo científico publicado en 2000

Hydrophobic polymers for orodispersible films: a quality by design approach.

artículo científico publicado en 2016

Impact of anti-PLK1 siRNA-containing F3-targeted liposomes on the viability of both cancer and endothelial cells.

artículo científico publicado en 2013

Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone.

artículo científico publicado en 2009

Improving lipoplex-mediated gene transfer into C6 glioma cells and primary neurons.

artículo científico publicado en 2004

In vitro modulation of Bcl-2 levels in small cell lung cancer cells: effects on cell viability.

artículo científico publicado en 2010

Inoculated Cell Density as a Determinant Factor of the Growth Dynamics and Metastatic Efficiency of a Breast Cancer Murine Model

artículo científico publicado en 2016

Interaction of S413-PV cell penetrating peptide with model membranes: relevance to peptide translocation across biological membranes

article

Kinetic analysis of the initial steps involved in lipoplex--cell interactions: effect of various factors that influence transfection activity.

artículo científico publicado en 2001

Ligand-guided optimization of CXCR4 homology models for virtual screening using a multiple chemotype approach.

artículo científico publicado en 2010

Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges

artículo científico publicado en 2012

Liposomal and viral vectors for gene therapy of the central nervous system.

artículo científico publicado en 2005

Liposomal imatinib-mitoxantrone combination: formulation development and therapeutic evaluation in an animal model of prostate cancer.

artículo científico publicado en 2011

Meeting the needs of breast cancer: A nucleolin's perspective.

artículo científico publicado en 2018

Modeling dissolution of sparingly soluble multisized powders.

artículo científico publicado en 1997

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers

artículo científico publicado en 2018

Mucoadhesive oral films: The potential for unmet needs

artículo científico

New halogenated water-soluble chlorin and bacteriochlorin as photostable PDT sensitizers: synthesis, spectroscopy, photophysics, and in vitro photosensitizing efficacy.

artículo científico publicado en 2010

Novel oleanolic vinyl boronates: synthesis and antitumor activity.

artículo científico publicado en 2013

On the formulation of pH-sensitive liposomes with long circulation times.

artículo científico publicado en 2004

Oral films: Current status and future perspectives II - Intellectual property, technologies and market needs

artículo científico

Oral films: Current status and future perspectives: I - Galenical development and quality attributes.

artículo científico publicado en 2015

Outlining critical quality attributes (CQAs) as guidance for the development of orodispersible films.

artículo científico publicado en 2016

Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity.

artículo científico publicado en 2002

Physicochemical properties of transferrin-associated lipopolyplexes and their role in biological activity.

artículo científico publicado en 2009

Quality by design in pharmaceutical manufacturing: A systematic review of current status, challenges and future perspectives

artículo científico publicado en 2019

S4(13)-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA.

artículo científico publicado en 2008

Schedule treatment design and quantitative in vitro evaluation of chemotherapeutic combinations for metastatic prostate cancer therapy.

artículo científico publicado en 2010

Selective cytotoxicity of oxysterols through structural modulation on rings A and B. Synthesis, in vitro evaluation, and SAR.

artículo científico publicado en 2011

Simultaneous evaluation of viability and Bcl-2 in small-cell lung cancer.

artículo científico publicado en 2008

Sterically stabilized ph-sensitive liposomes

artículo científico publicado en 2004

Sterols as anticancer agents: synthesis of ring-B oxygenated steroids, cytotoxic profile, and comprehensive SAR analysis.

artículo científico publicado en 2010

Successful transfection of lymphocytes by ternary lipoplexes.

artículo científico publicado en 1999

Survivin silencing as a promising strategy to enhance the sensitivity of cancer cells to chemotherapeutic agents.

artículo científico publicado en 2011

Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: impact on the treatment of breast cancer ⬇️

artículo científico publicado el 30 de julio de 2011

Targeted gene delivery into peripheral sensorial neurons mediated by self-assembled vectors composed of poly(ethylene imine) and tetanus toxin fragment c.

artículo científico publicado en 2010

Targeting cancer stem cells and non-stem cancer cells: the potential of lipid-based nanoparticles.

artículo científico publicado en 2017

Technology evaluation: LErafAON, NeoPharm.

artículo científico publicado en 2003

Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury.

artículo científico publicado en 2005

Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo.

artículo científico publicado en 2009

Tf-lipoplexes for neuronal siRNA delivery: a promising system to mediate gene silencing in the CNS.

artículo científico publicado en 2008

The cancer stem cell phenotype as a determinant factor of the heterotypic nature of breast tumors

artículo científico publicado en 2017

Therapeutic Implications of the Molecular and Immune Landscape of Triple-Negative Breast Cancer.

artículo científico publicado en 2017

Transfection of human macrophages by lipoplexes via the combined use of transferrin and pH-sensitive peptides

scientific article published on 01 February 1999

Transfection of oral cancer cells mediated by transferrin-associated lipoplexes: mechanisms of cell death induced by herpes simplex virus thymidine kinase/ganciclovir therapy.

artículo científico publicado en 2006

Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response.

artículo científico publicado en 2008

Transferrin-associated lipoplexes as gene delivery systems: relevance of mode of preparation and biophysical properties.

artículo científico publicado en 2008

Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment.

artículo científico publicado en 2013

Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activities.

artículo científico publicado en 2004

siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing.

artículo científico publicado en 2007

Lista de obras de

A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides.

African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infection.

African swine fever virus p37 structural protein is localized in nuclear foci containing the viral DNA at early post-infection times.

Anticancer activity and antibody-dependent cell-mediated cytotoxicity of novel anti-nucleolin antibodies.

Association of albumin or protamine to lipoplexes: enhancement of transfection and resistance to serum.

Biodistribution and photodynamic efficacy of a water-soluble, stable, halogenated bacteriochlorin against melanoma.

Biophysical characterization of cationic liposome-DNA complexes and their interaction with cells.

Cationic lipid-DNA complexes in gene delivery: from biophysics to biological applications.

Cationic liposome-DNA complexes as gene delivery vectors: Development and behaviour towards bone-like cells.

Cellular and molecular events associated with the antitumor response induced by the cytosine deaminase/5-fluorocytosine suicide gene therapy system in a rat liver metastasis model.

Cellular uptake of S4 13 -PV peptide occurs upon conformational changes induced by peptide–membrane interactions

Challenging the future of siRNA therapeutics against cancer: the crucial role of nanotechnology

Ciprofloxacin sensitizes hormone-refractory prostate cancer cell lines to doxorubicin and docetaxel treatment on a schedule-dependent manner.

Co-encapsulation of anti-BCR-ABL siRNA and imatinib mesylate in transferrin receptor-targeted sterically stabilized liposomes for chronic myeloid leukemia treatment.

Combined effects of singlet oxygen and hydroxyl radical in photodynamic therapy with photostable bacteriochlorins: Evidence from intracellular fluorescence and increased photodynamic efficacy in vitro

DNA pre-condensation with an amino acid-based cationic amphiphile. A viable approach for liposome-based gene delivery.

Delivery of antiviral agents in liposomes.

Development, characterization and in vitro evaluation of single or co-loaded imatinib mesylate liposomal formulations.

Enhanced inhibition of HIV-1 replication in macrophages by antisense oligonucleotides, ribozymes and acyclic nucleoside phosphonate analogs delivered in pH-sensitive liposomes.

Gene delivery by cationic liposome-DNA complexes containing transferrin or serum albumin.

Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusigenic peptides.

Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum.

Hydrophobic polymers for orodispersible films: a quality by design approach.

Impact of anti-PLK1 siRNA-containing F3-targeted liposomes on the viability of both cancer and endothelial cells.

Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone.

Improving lipoplex-mediated gene transfer into C6 glioma cells and primary neurons.

In vitro modulation of Bcl-2 levels in small cell lung cancer cells: effects on cell viability.

Inoculated Cell Density as a Determinant Factor of the Growth Dynamics and Metastatic Efficiency of a Breast Cancer Murine Model

Interaction of S413-PV cell penetrating peptide with model membranes: relevance to peptide translocation across biological membranes

Kinetic analysis of the initial steps involved in lipoplex--cell interactions: effect of various factors that influence transfection activity.

Ligand-guided optimization of CXCR4 homology models for virtual screening using a multiple chemotype approach.

Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges

Liposomal and viral vectors for gene therapy of the central nervous system.

Liposomal imatinib-mitoxantrone combination: formulation development and therapeutic evaluation in an animal model of prostate cancer.

Meeting the needs of breast cancer: A nucleolin's perspective.

Modeling dissolution of sparingly soluble multisized powders.

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers

Mucoadhesive oral films: The potential for unmet needs

New halogenated water-soluble chlorin and bacteriochlorin as photostable PDT sensitizers: synthesis, spectroscopy, photophysics, and in vitro photosensitizing efficacy.

Novel oleanolic vinyl boronates: synthesis and antitumor activity.

On the formulation of pH-sensitive liposomes with long circulation times.

Oral films: Current status and future perspectives II - Intellectual property, technologies and market needs

Oral films: Current status and future perspectives: I - Galenical development and quality attributes.

Outlining critical quality attributes (CQAs) as guidance for the development of orodispersible films.

Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity.

Physicochemical properties of transferrin-associated lipopolyplexes and their role in biological activity.

Quality by design in pharmaceutical manufacturing: A systematic review of current status, challenges and future perspectives

S4(13)-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA.

Schedule treatment design and quantitative in vitro evaluation of chemotherapeutic combinations for metastatic prostate cancer therapy.

Selective cytotoxicity of oxysterols through structural modulation on rings A and B. Synthesis, in vitro evaluation, and SAR.

Simultaneous evaluation of viability and Bcl-2 in small-cell lung cancer.

Sterically stabilized ph-sensitive liposomes

Sterols as anticancer agents: synthesis of ring-B oxygenated steroids, cytotoxic profile, and comprehensive SAR analysis.

Successful transfection of lymphocytes by ternary lipoplexes.

Survivin silencing as a promising strategy to enhance the sensitivity of cancer cells to chemotherapeutic agents.

Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: impact on the treatment of breast cancer ⬇️

Targeted gene delivery into peripheral sensorial neurons mediated by self-assembled vectors composed of poly(ethylene imine) and tetanus toxin fragment c.

Targeting cancer stem cells and non-stem cancer cells: the potential of lipid-based nanoparticles.

Technology evaluation: LErafAON, NeoPharm.

Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury.

Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo.

Tf-lipoplexes for neuronal siRNA delivery: a promising system to mediate gene silencing in the CNS.

The cancer stem cell phenotype as a determinant factor of the heterotypic nature of breast tumors

Therapeutic Implications of the Molecular and Immune Landscape of Triple-Negative Breast Cancer.

Transfection of human macrophages by lipoplexes via the combined use of transferrin and pH-sensitive peptides

Transfection of oral cancer cells mediated by transferrin-associated lipoplexes: mechanisms of cell death induced by herpes simplex virus thymidine kinase/ganciclovir therapy.

Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response.

Transferrin-associated lipoplexes as gene delivery systems: relevance of mode of preparation and biophysical properties.

Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment.

Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activities.

siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing.