Lista de obras - Alberto Ballestrero - Dominio Público Uruguay

5-fluorouracil causes endothelial cell senescence: potential protective role of glucagon-like peptide 1.

artículo científico publicado en 2017

A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11) in a patient with acute myeloid leukemia

artículo científico publicado en 2008

A T315I mutation in e19a2 BCR/ABL1 chronic myeloid leukemia responding to dasatinib.

artículo científico publicado en 2010

A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation

scientific article published on 05 April 2019

A phase II study of neoadjuvant bevacizumab plus capecitabine and concomitant radiotherapy in patients with locally advanced rectal cancer

scientific article published on 03 January 2012

APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells

artículo científico publicado en 2015

APO866 activity in hematologic malignancies: a preclinical in vitro study.

artículo científico publicado en 2009

Adjuvant chemotherapy with high-dose cyclophosphamide, etoposide and cisplatin intensification without progenitor cell support in breast cancer patients with ten or more involved nodes: 5-year results of a pilot trial.

artículo científico publicado en 2001

Adjuvant high-dose chemotherapy with autologous hematopoietic stem cell support for high-risk primary breast cancer: results from the Italian national registry.

artículo científico publicado en 2013

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies.

artículo científico publicado en 2015

Afatinib resistance in non-small cell lung cancer involves the PI3K/AKT and MAPK/ERK signalling pathways and epithelial-to-mesenchymal transition.

artículo científico publicado en 2014

Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.

artículo científico publicado en 2011

Autologous peripheral blood stem cells (PBSC) in breast cancer

artículo científico publicado en 2002

Bi-weekly docetaxel and gemcitabine regimen in her-2-negative and anthracycline-pretreated metastatic breast cancer patients: a multicenter phase II trial

artículo científico publicado en 2011

CDKN2A germline mutations are not associated with poor survival in an Italian cohort of melanoma patients

article

Cardiac toxicity of trastuzumab in metastatic breast cancer patients previously treated with high-dose chemotherapy: a retrospective study

artículo científico publicado en 2006

Clinico-pathological and transcriptomic determinants of SLFN11 expression in invasive breast carcinoma.

artículo científico publicado en 2015

Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer

scientific article published on 29 April 2019

Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.

artículo científico publicado en 2005

Correction to: Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer

artículo científico publicado en 2019

Correction: Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations.

artículo científico publicado en 2018

DNA aneuploidy relationship with patient age and tobacco smoke in OPMDs/OSCCs

artículo científico publicado en 2017

DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment.

artículo científico

Discontinuation of first-line bevacizumab in metastatic colorectal cancer: the BEAWARE Italian Observational Study

artículo científico publicado en 2019

Dose-dense vinorelbine and paclitaxel with granulocyte colony-stimulating factor in metastatic breast cancer patients: anti-tumor activity and peripheral blood progenitor cell mobilization capability.

artículo científico publicado en 2003

Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status.

artículo científico publicado en 2016

Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments: concordance with experimental results.

artículo científico publicado en 2010

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition

artículo científico publicado en 2015

Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes: possible relevance to the assays for the detection of micrometastatic breast cancer.

artículo científico publicado en 2005

Effects of three cytokine regimens on hematologic recovery and progenitor cell mobilization after high-dose cyclophosphamide, etoposide, and cisplatin.

artículo científico publicado en 2000

Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.

artículo científico publicado en 2004

Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells

artículo científico publicado en 2015

Extracellular cytolysis by leukaemic blast cells ⬇️

artículo científico publicado el 1 de enero de 1984

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition.

artículo científico publicado en 2015

Four-step high-dose sequential chemotherapy with double hematopoietic progenitor-cell rescue for metastatic breast cancer

artículo científico publicado en 1995

Frailty assessment in elective gastrointestinal oncogeriatric surgery: Predictors of one-year mortality and functional status

scientific article published on 07 May 2019

Germline mutations in the von Hippel-Lindau gene in Italian patients.

artículo científico publicado en 2009

Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression

artículo científico publicado en 2010

HMGA2 overexpression in polycythemia vera with t(12;21)(q14;q22)

scientific article published on 01 September 2007

Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases.

artículo científico publicado en 2017

Heterogeneity and frequency of BRAF mutations in primary melanoma: Comparison between molecular methods and immunohistochemistry

scientific article published on 22 December 2016

High frequency of trisomy 8 in acute promyelocytic leukemia: a fluorescence in situ hybridization study.

artículo científico

High-dose mitoxantrone with peripheral blood progenitor cell rescue: toxicity, pharmacokinetics and implications for dosage and schedule ⬇️

artículo científico publicado el 1 de enero de 1997

Histone deacetylase inhibitors affect dendritic cell differentiation and immunogenicity

scientific article published on 01 July 2007

Integrated Somatic and Germline Whole-Exome Sequencing Analysis in Women with Lung Cancer after a Previous Breast Cancer.

artículo científico publicado en 2019

Kinase domain mutations of BCR-ABL identified at diagnosis before imatinib-based therapy are associated with progression in patients with high Sokal risk chronic phase chronic myeloid leukemia.

artículo científico publicado en 2010

Long-term survival in patients with metastatic breast cancer receiving intensified chemotherapy and stem cell rescue: data from the Italian registry.

artículo científico publicado en 2012

Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: implications for treatment of metastatic colorectal cancer

artículo científico publicado en 2012

Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase.

artículo científico publicado en 2005

Molecular characterization of an Italian series of sporadic GISTs.

artículo científico publicado en 2013

Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 tri

scientific article published on 08 August 2019

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice.

artículo científico publicado en 2013

Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity

artículo científico publicado en 2014

Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair

artículo científico publicado en 2017

Parameter space exploration within dynamic simulations of signaling networks.

artículo científico publicado en 2013

Prospective study to optimize care and improve knowledge on ovarian function and/or fertility preservation in young breast cancer patients: Results of the pilot phase of the PREgnancy and FERtility (PREFER) study

scientific article published on 22 June 2018

Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells.

artículo científico publicado en 2006

Proteasome inhibitors as immunosuppressants: biological rationale and clinical experience.

artículo científico

Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents

artículo científico publicado en 2012

Quantitative Real Time PCR assessment of hormonal receptors and HER2 status on fine-needle aspiration pre-operatory specimens from a prospectively accrued cohort of women with suspect breast malignant lesions

artículo científico publicado en 2013

Rejuvenating sirtuins: the rise of a new family of cancer drug targets

artículo científico publicado en 2013

Reliability and reproducibility of a RNA preamplification method for low-density array analysis from formalin-fixed paraffin-embedded breast cancer samples.

artículo científico

Report on the first SLFN11 monothematic workshop: from function to role as a biomarker in cancer

artículo científico publicado en 2017

Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination

artículo científico publicado en 2001

Role of angiogenesis inhibitors in colorectal cancer: sensitive and insensitive tumors.

artículo científico

Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer

scientific article published on 20 June 2019

Sequential dose-dense 5-fluorouracil, epirubicin and cyclophosphamide followed by docetaxel in patients with early breast cancer with four or more positive lymph nodes

artículo científico publicado en 2014

Specific conjunctival challenge in polysensitized subjects

scientific article published on 01 September 1997

Squalene epoxidase as a promising metabolic target in cancer treatment

artículo científico publicado en 2018

Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer

artículo científico publicado en 2016

Squamous cell carcinoma of the breast: a case report.

scientific article published on 10 July 2009

Standard-dose recombinant human granulocyte colony-stimulating factor (rhG-CSF) allows safe and repeated administration of high-dose cyclophosphamide, etoposide, and cisplatin (CEP)

artículo científico publicado en 1997

Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer.

artículo científico

Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial.

artículo científico publicado en 2016

The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level.

artículo científico publicado en 2016

The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer.

artículo científico publicado en 2013

The induction of distinct cytokine cascades correlates with different effects of granulocyte-colony stimulating factor and granulocyte/macrophage-colony-stimulating factor on the lymphocyte compartment in the course of high-dose chemotherapy for bre

artículo científico publicado en 1999

The use of dendritic cells in cancer immunotherapy

scientific article published on 04 December 2007

Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells.

artículo científico publicado en 2004

Lista de obras de Alberto Ballestrero

5-fluorouracil causes endothelial cell senescence: potential protective role of glucagon-like peptide 1.

A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11) in a patient with acute myeloid leukemia

A T315I mutation in e19a2 BCR/ABL1 chronic myeloid leukemia responding to dasatinib.

A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation

A phase II study of neoadjuvant bevacizumab plus capecitabine and concomitant radiotherapy in patients with locally advanced rectal cancer

APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells

APO866 activity in hematologic malignancies: a preclinical in vitro study.

Adjuvant chemotherapy with high-dose cyclophosphamide, etoposide and cisplatin intensification without progenitor cell support in breast cancer patients with ten or more involved nodes: 5-year results of a pilot trial.

Adjuvant high-dose chemotherapy with autologous hematopoietic stem cell support for high-risk primary breast cancer: results from the Italian national registry.

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies.

Afatinib resistance in non-small cell lung cancer involves the PI3K/AKT and MAPK/ERK signalling pathways and epithelial-to-mesenchymal transition.

Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.

Autologous peripheral blood stem cells (PBSC) in breast cancer

Bi-weekly docetaxel and gemcitabine regimen in her-2-negative and anthracycline-pretreated metastatic breast cancer patients: a multicenter phase II trial

CDKN2A germline mutations are not associated with poor survival in an Italian cohort of melanoma patients

Cardiac toxicity of trastuzumab in metastatic breast cancer patients previously treated with high-dose chemotherapy: a retrospective study

Clinico-pathological and transcriptomic determinants of SLFN11 expression in invasive breast carcinoma.

Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer

Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.

Correction to: Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer

Correction: Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations.

DNA aneuploidy relationship with patient age and tobacco smoke in OPMDs/OSCCs

DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment.

Discontinuation of first-line bevacizumab in metastatic colorectal cancer: the BEAWARE Italian Observational Study

Dose-dense vinorelbine and paclitaxel with granulocyte colony-stimulating factor in metastatic breast cancer patients: anti-tumor activity and peripheral blood progenitor cell mobilization capability.

Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status.

Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments: concordance with experimental results.

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition

Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes: possible relevance to the assays for the detection of micrometastatic breast cancer.

Effects of three cytokine regimens on hematologic recovery and progenitor cell mobilization after high-dose cyclophosphamide, etoposide, and cisplatin.

Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.

Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells

Extracellular cytolysis by leukaemic blast cells ⬇️

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition.

Four-step high-dose sequential chemotherapy with double hematopoietic progenitor-cell rescue for metastatic breast cancer

Frailty assessment in elective gastrointestinal oncogeriatric surgery: Predictors of one-year mortality and functional status

Germline mutations in the von Hippel-Lindau gene in Italian patients.

Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression

HMGA2 overexpression in polycythemia vera with t(12;21)(q14;q22)

Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases.

Heterogeneity and frequency of BRAF mutations in primary melanoma: Comparison between molecular methods and immunohistochemistry

High frequency of trisomy 8 in acute promyelocytic leukemia: a fluorescence in situ hybridization study.

High-dose mitoxantrone with peripheral blood progenitor cell rescue: toxicity, pharmacokinetics and implications for dosage and schedule ⬇️

Histone deacetylase inhibitors affect dendritic cell differentiation and immunogenicity

Integrated Somatic and Germline Whole-Exome Sequencing Analysis in Women with Lung Cancer after a Previous Breast Cancer.

Kinase domain mutations of BCR-ABL identified at diagnosis before imatinib-based therapy are associated with progression in patients with high Sokal risk chronic phase chronic myeloid leukemia.

Long-term survival in patients with metastatic breast cancer receiving intensified chemotherapy and stem cell rescue: data from the Italian registry.

Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: implications for treatment of metastatic colorectal cancer

Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase.

Molecular characterization of an Italian series of sporadic GISTs.

Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 tri

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice.

Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity

Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair

Parameter space exploration within dynamic simulations of signaling networks.

Prospective study to optimize care and improve knowledge on ovarian function and/or fertility preservation in young breast cancer patients: Results of the pilot phase of the PREgnancy and FERtility (PREFER) study

Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells.

Proteasome inhibitors as immunosuppressants: biological rationale and clinical experience.

Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents

Quantitative Real Time PCR assessment of hormonal receptors and HER2 status on fine-needle aspiration pre-operatory specimens from a prospectively accrued cohort of women with suspect breast malignant lesions

Rejuvenating sirtuins: the rise of a new family of cancer drug targets

Reliability and reproducibility of a RNA preamplification method for low-density array analysis from formalin-fixed paraffin-embedded breast cancer samples.

Report on the first SLFN11 monothematic workshop: from function to role as a biomarker in cancer

Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination

Role of angiogenesis inhibitors in colorectal cancer: sensitive and insensitive tumors.

Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer

Sequential dose-dense 5-fluorouracil, epirubicin and cyclophosphamide followed by docetaxel in patients with early breast cancer with four or more positive lymph nodes

Specific conjunctival challenge in polysensitized subjects

Squalene epoxidase as a promising metabolic target in cancer treatment

Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer

Squamous cell carcinoma of the breast: a case report.

Standard-dose recombinant human granulocyte colony-stimulating factor (rhG-CSF) allows safe and repeated administration of high-dose cyclophosphamide, etoposide, and cisplatin (CEP)

Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer.

Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial.

The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level.

The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer.

The induction of distinct cytokine cascades correlates with different effects of granulocyte-colony stimulating factor and granulocyte/macrophage-colony-stimulating factor on the lymphocyte compartment in the course of high-dose chemotherapy for bre

The use of dendritic cells in cancer immunotherapy

Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells.