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3-Aryl-2-quinolone derivatives: synthesis and characterization of in vitro and in vivo antitumor effects with emphasis on a new therapeutical target connected with cell migration

artículo científico publicado en 2002

Correction: Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

artículo científico publicado en 2018

Cytotoxic nucleoside analogues: different strategies to improve their clinical efficacy.

artículo científico publicado en 2008

Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis.

artículo científico publicado en 2014

Indolobenzazepin-7-ones and 6-, 8-, and 9-membered ring derivatives as tubulin polymerization inhibitors: synthesis and structure--activity relationship studies

artículo científico publicado en 2009

Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives.

artículo científico publicado en 2012

Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex.

artículo científico publicado en 2008

Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases

artículo científico publicado en 2007

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine

artículo científico publicado en 2008

New 1-arylindoles based serotonin 5-HT7 antagonists. Synthesis and binding evaluation studies

scientific article published on 28 January 2014

New insights into homopiperazine-based 5-HT1A/5-HT7R ligands: synthesis and biological evaluation

artículo científico publicado en 2010

Room-Temperature and Transition-Metal-Free Intramolecular α-Arylation of Ketones: A Mild Access to Tetracyclic Indoles and 7-Azaindoles

artículo científico publicado en 2018

Structure-activity relationship and multidrug resistance study of new S-trityl-L-cysteine derivatives as inhibitors of Eg5

artículo científico publicado en 2011

Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.

artículo científico publicado en 2008

Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres

artículo científico publicado en 2007

Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives.

artículo científico publicado en 2009

Synthesis and biological evaluation in rat and cat of [18F]12ST05 as a potential 5-HT6 PET radioligand

artículo científico publicado en 2007

Synthesis and in vitro cytotoxic evaluation of N-substituted benzo[5,6]cycloheptal[b]indoles

artículo científico publicado en 2000

Synthesis, cytotoxicity, DNA interaction and topoisomerase II inhibition properties of tetrahydropyrrolo[3,4-a]carbazole-1,3-dione and tetrahydropyrido-[3,2-b]pyrrolo[3,4-g]indole-1,3-dione derivatives.

artículo científico publicado en 2001

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.

artículo científico publicado en 2018

Targeting low molecular weight cyclin E (LMW-E) in breast cancer.

artículo científico publicado en 2011

Unexpected matrix interactions in liquid secondary ion mass spectrometry of two pyranosyl mercaptans

artículo científico publicado en 2011

Use of ATP analogs to inhibit HIV-1 transcription

artículo científico publicado en 2012