Lista de obras - Rima Rozen - Dominio Público Uruguay

A common polymorphism in methionine synthase reductase increases risk of premature coronary artery disease

artículo científico publicado en 2000

A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida

artículo científico publicado en 1999

A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development

scientific journal article

A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment.

artículo científico publicado en 2010

Age Dependence of the Influence of Methylenetetrahydrofolate Reductase Genotype on Plasma Homocysteine Level ⬇️

artículo científico publicado el 1 de noviembre de 2003

Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice.

artículo científico publicado en 2008

Antioxidant vitamins, long-chain fatty acids, and spontaneous preterm birth

artículo científico publicado en 2009

Antisense inhibition of methylenetetrahydrofolate reductase reduces cancer cell survival in vitro and tumor growth in vivo

artículo científico publicado en 2005

ApcMin/+ mouse model of colon cancer: gene expression profiling in tumors

artículo científico publicado en 2004

Assignment of the gene (UQCRFS1) for the Rieske iron-sulfur protein subunit of the mitochondrial cytochrome bc1 complex to the 22q13 and 19q12-q13.1 regions of the human genome

artículo científico publicado en 1994

Assignment of the gene for the core protein II (UQCRC2) subunit of the mitochondrial cytochrome bc1 complex to human chromosome 16p12

artículo científico publicado en 1993

Assignment of the gene for the cytochrome c1 subunit of the mitochondrial cytochrome bc1 complex (CYC1) to human chromosome 8q24.3

artículo científico publicado en 1994

Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption

artículo científico publicado en 2007

Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency

scientific journal article

Biochemistry and genetics of folate metabolism.

artículo científico publicado en 2010

Cerebral vascular complication and hyperhomocysteinemia in a cystinotic uremic child

artículo científico publicado en 1999

Characterization of a pseudogene for murine methylenetetrahydrofolate reductase

artículo científico publicado el 1 de octubre de 2003

Characterization of mutations in severe methylenetetrahydrofolate reductase deficiency reveals an FAD-responsive mutation

artículo científico publicado en 2003

Characterization of six novel mutations in the methylenetetrahydrofolate reductase (MTHFR) gene in patients with homocystinuria

article

Common variant in betaine-homocysteine methyltransferase (BHMT) and risk for spina bifida

article

Complete deficiency of methylenetetrahydrofolate reductase in mice is associated with impaired retinal function and variable mortality, hematological profiles, and reproductive outcomes.

artículo científico publicado en 2010

DNA methyltransferase 1 (Dnmt1) mutation affects Snrpn imprinting in the mouse male germ line

artículo científico publicado en 2012

Design and rationale of a genetic cohort study on congenital cardiac disease: experiences from a multi-institutional platform in Quebec

Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.

artículo científico publicado en 2010

Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice

artículo científico publicado en 2012

Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARα, interferon-γ, and interleukin-10

artículo científico publicado en 2012

Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency

scientific article published on 04 October 2018

Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice

artículo científico publicado en 2003

Effect of hyperhomocystinemia and hypertension on endothelial function in methylenetetrahydrofolate reductase-deficient mice

artículo científico publicado en 2003

Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency

scientific journal article

Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study.

artículo científico publicado en 2003

Elevated homocysteine reduces apolipoprotein A-I expression in hyperhomocysteinemic mice and in males with coronary artery disease

artículo científico publicado en 2006

Endoplasmic reticulum stress increases the expression of methylenetetrahydrofolate reductase through the IRE1 transducer

artículo científico publicado en 2007

Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice

artículo científico publicado en 2015

Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk

artículo científico publicado en 2003

Frequency and phenotypic consequences of the 3199del6 CFTR mutation in French Canadians

scientific article published on 01 March 2005

Genes with aberrant expression in murine preneoplastic intestine show epigenetic and expression changes in normal mucosa of colon cancer patients

artículo científico publicado en 2013

Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice.

artículo científico publicado en 2006

Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects

article

High Dietary Folate in Mice Alters Immune Response and Reduces Survival after Malarial Infection

artículo científico publicado en 2015

High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.

artículo científico publicado en 2017

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.

artículo científico publicado en 2015

High folic acid intake increases methylation-dependent expression of Lsr and dysregulates hepatic cholesterol homeostasis

artículo científico publicado en 2020

High intake of folic acid disrupts embryonic development in mice ⬇️

artículo científico publicado el 22 de diciembre de 2010

Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF-kappaB/iNOS.

artículo científico publicado en 2008

Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency

artículo científico publicado en 2003

Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders

artículo científico publicado en 1996

Hyperhomocysteinemia is associated with hypertriglyceridemia in mice with methylenetetrahydrofolate reductase deficiency.

artículo científico publicado en 2009

Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice

artículo científico publicado en 2003

Impact of methylenetetrahydrofolate reductase deficiency and low dietary folate on the development of neural tube defects in splotch mice

artículo científico publicado en 2006

Increased resistance to malaria in mice with methylenetetrahydrofolate reductase (Mthfr) deficiency suggests a mechanism for selection of the MTHFR 677C>T (c.665C>T) variant

artículo científico publicado en 2014

Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation

artículo científico publicado en 2004

Influence of methylenetetrahydrofolate reductase genotype, age, vitamin B-12, and folate status on plasma homocysteine in children

artículo científico publicado en 2000

Inherited Thrombophilia and Preeclampsia Within a Multicenter Cohort: The Montreal Preeclampsia Study

Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study

artículo científico publicado en 2008

Interview with Rima Rozen

artículo científico publicado en 2008

Intestinal neoplasia induced by low dietary folate is associated with altered tumor expression profiles and decreased apoptosis in mouse normal intestine

artículo científico publicado en 2009

Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease.

artículo científico publicado en 2003

Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects

artículo científico publicado en 2018

Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice

artículo científico publicado en 2010

Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN‐γ in spleen and placenta, and through reduction of methylation potential ⬇️

artículo científico publicado el 30 de octubre de 2012

Low dietary folate initiates intestinal tumors in mice, with altered expression of G2-M checkpoint regulators polo-like kinase 1 and cell division cycle 25c.

artículo científico publicado en 2006

MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice

artículo científico publicado en 2015

MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring

artículo científico publicado en 2015

Maternal folate deficiency affects proliferation, but not apoptosis, in embryonic mouse heart

artículo científico publicado en 2006

Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice

artículo científico publicado en 2005

Mefolinate (5-methyltetrahydrofolate), but not folic acid, decreases mortality in an animal model of severe methylenetetrahydrofolate reductase deficiency

artículo científico publicado en 2008

Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase

artículo científico publicado en 2007

Methionine synthase reductase deficiency results in adverse reproductive outcomes and congenital heart defects in mice

artículo científico publicado en 2008

Methotrexate-induced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase.

artículo científico publicado en 2009

Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid

artículo científico publicado en 2003

Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice

artículo científico publicado en 2009

Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy ⬇️

artículo científico publicado el 1 de mayo de 2003

Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians

artículo científico publicado en 1996

Methylenetetrahydrofolate reductase: a link between folate and riboflavin?

artículo científico publicado en 2002

Mice deficient in methylenetetrahydrofolate reductase exhibit tissue-specific distribution of folates

artículo científico publicado en 2004

Microarray analysis of brain RNA in mice with methylenetetrahydrofolate reductase deficiency and hyperhomocysteinemia

artículo científico publicado en 2002

Mild methylenetetrahydrofolate reductase deficiency alters inflammatory and lipid pathways in liver

artículo científico publicado en 2018

Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism

artículo científico publicado en 2020

Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development

artículo científico publicado en 2016

Moderately high intake of folic acid has a negative impact on mouse embryonic development ⬇️

artículo científico publicado el 2 de noviembre de 2012

Molecular cloning, expression and physical mapping of the human methionine synthase reductase gene

artículo científico publicado en 1999

Molecular genetics of MTHFR: polymorphisms are not all benign

artículo científico publicado en 2007

Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism.

artículo científico publicado en 2014

Mthfr as a modifier of the retinal phenotype of Crb1(rd8/rd8) mice.

artículo científico publicado en 2015

Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms

artículo científico publicado en 2002

Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors

artículo científico publicado en 2016

Murine diet/tissue and human brain tumorigenesis alter Mthfr/MTHFR 5'-end methylation

artículo científico publicado en 2016

Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation

artículo científico publicado en 2010

Oncogenic role of PDK4 in human colon cancer cells

artículo científico publicado en 2017

Plasma homocysteine concentration changes after renal transplantation in children

artículo científico publicado en 2002

Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome

artículo científico publicado en 2000

Postnatal cerebellar defects in mice deficient in methylenetetrahydrofolate reductase

artículo científico publicado en 2005

Prenatal diagnosis for severe methylenetetrahydrofolate reductase deficiency by linkage analysis and enzymatic assay.

artículo científico publicado en 2005

Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency

artículo científico publicado en 2014

Regulatory studies of murine methylenetetrahydrofolate reductase reveal two major promoters and NF-kappaB sensitivity

artículo científico publicado en 2005

Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.

artículo científico publicado en 1996

Retinal Ganglion Cell Loss and Mild Vasculopathy in Methylene Tetrahydrofolate Reductase (Mthfr)-Deficient Mice: A Model of Mild Hyperhomocysteinemia

artículo científico publicado en 2015

Risk of congenital heart defects is influenced by genetic variation in folate metabolism

artículo científico publicado en 2012

SLC7A9 mutations in all three cystinuria subtypes

artículo científico publicado en 2002

Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus.

artículo científico publicado en 2012

Severe methylenetetrahydrofolate reductase deficiency: clinical clues to a potentially treatable cause of adult-onset hereditary spastic paraplegia

artículo científico publicado en 2014

Small artery mechanics in hyperhomocysteinemic mice: effects of angiotensin II.

artículo científico publicado en 2004

Spina bifida, folate metabolism, and dietary folate intake in a Northern Canadian aboriginal population

artículo científico publicado en 2002

Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism ⬇️

artículo científico publicado el 19 de agosto de 2010

Strain differences in mice highlight the role of DNA damage in neoplasia induced by low dietary folate

artículo científico publicado en 2008

Strain-specific defects in testicular development and sperm epigenetic patterns in 5,10-methylenetetrahydrofolate reductase-deficient mice

artículo científico publicado en 2010

Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice ⬇️

artículo científico publicado el 1 de enero de 2002

Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair

artículo científico publicado en 2010

Targeted insertion of two Mthfr promoters in mice reveals temporal- and tissue-specific regulation ⬇️

artículo científico publicado el 19 de julio de 2011

Testicular MTHFR deficiency may explain sperm DNA hypomethylation associated with high dose folic acid supplementation

artículo científico publicado en 2018

The MTHFD1 1958G>A variant is associated with elevated C-reactive protein and body mass index in Canadian women from a premature birth cohort

artículo científico publicado en 2013

The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects

artículo científico publicado en 2009

The curly-tail (ct) mouse, an animal model of neural tube defects, displays altered homocysteine metabolism without folate responsiveness or a defect in Mthfr

artículo científico publicado en 2002

Transient neonatal cystinuria

artículo científico publicado en 2005

Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency

artículo científico publicado en 2008

Vasculopathic and thrombophilic risk factors for spontaneous preterm birth

artículo científico publicado en 2009

β,β-Carotene 15,15′-monooxygenase and its substrate β-carotene modulate migration and invasion in colorectal carcinoma cells ⬇️

artículo científico publicado el 26 de junio de 2013

Lista de obras de Rima Rozen

A common polymorphism in methionine synthase reductase increases risk of premature coronary artery disease

A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida

A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development

A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment.

Age Dependence of the Influence of Methylenetetrahydrofolate Reductase Genotype on Plasma Homocysteine Level ⬇️

Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice.

Antioxidant vitamins, long-chain fatty acids, and spontaneous preterm birth

Antisense inhibition of methylenetetrahydrofolate reductase reduces cancer cell survival in vitro and tumor growth in vivo

ApcMin/+ mouse model of colon cancer: gene expression profiling in tumors

Assignment of the gene (UQCRFS1) for the Rieske iron-sulfur protein subunit of the mitochondrial cytochrome bc1 complex to the 22q13 and 19q12-q13.1 regions of the human genome

Assignment of the gene for the core protein II (UQCRC2) subunit of the mitochondrial cytochrome bc1 complex to human chromosome 16p12

Assignment of the gene for the cytochrome c1 subunit of the mitochondrial cytochrome bc1 complex (CYC1) to human chromosome 8q24.3

Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption

Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency

Biochemistry and genetics of folate metabolism.

Cerebral vascular complication and hyperhomocysteinemia in a cystinotic uremic child

Characterization of a pseudogene for murine methylenetetrahydrofolate reductase

Characterization of mutations in severe methylenetetrahydrofolate reductase deficiency reveals an FAD-responsive mutation

Characterization of six novel mutations in the methylenetetrahydrofolate reductase (MTHFR) gene in patients with homocystinuria

Common variant in betaine-homocysteine methyltransferase (BHMT) and risk for spina bifida

Complete deficiency of methylenetetrahydrofolate reductase in mice is associated with impaired retinal function and variable mortality, hematological profiles, and reproductive outcomes.

DNA methyltransferase 1 (Dnmt1) mutation affects Snrpn imprinting in the mouse male germ line

Design and rationale of a genetic cohort study on congenital cardiac disease: experiences from a multi-institutional platform in Quebec

Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.

Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice

Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARα, interferon-γ, and interleukin-10

Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency

Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice

Effect of hyperhomocystinemia and hypertension on endothelial function in methylenetetrahydrofolate reductase-deficient mice

Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency

Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study.

Elevated homocysteine reduces apolipoprotein A-I expression in hyperhomocysteinemic mice and in males with coronary artery disease

Endoplasmic reticulum stress increases the expression of methylenetetrahydrofolate reductase through the IRE1 transducer

Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice

Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk

Frequency and phenotypic consequences of the 3199del6 CFTR mutation in French Canadians

Genes with aberrant expression in murine preneoplastic intestine show epigenetic and expression changes in normal mucosa of colon cancer patients

Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice.

Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects

High Dietary Folate in Mice Alters Immune Response and Reduces Survival after Malarial Infection

High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.

High folic acid intake increases methylation-dependent expression of Lsr and dysregulates hepatic cholesterol homeostasis

High intake of folic acid disrupts embryonic development in mice ⬇️

Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF-kappaB/iNOS.

Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency

Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders

Hyperhomocysteinemia is associated with hypertriglyceridemia in mice with methylenetetrahydrofolate reductase deficiency.

Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice

Impact of methylenetetrahydrofolate reductase deficiency and low dietary folate on the development of neural tube defects in splotch mice

Increased resistance to malaria in mice with methylenetetrahydrofolate reductase (Mthfr) deficiency suggests a mechanism for selection of the MTHFR 677C>T (c.665C>T) variant

Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation

Influence of methylenetetrahydrofolate reductase genotype, age, vitamin B-12, and folate status on plasma homocysteine in children

Inherited Thrombophilia and Preeclampsia Within a Multicenter Cohort: The Montreal Preeclampsia Study

Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study

Interview with Rima Rozen

Intestinal neoplasia induced by low dietary folate is associated with altered tumor expression profiles and decreased apoptosis in mouse normal intestine

Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease.

Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects

Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice

Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN‐γ in spleen and placenta, and through reduction of methylation potential ⬇️

Low dietary folate initiates intestinal tumors in mice, with altered expression of G2-M checkpoint regulators polo-like kinase 1 and cell division cycle 25c.

MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice

MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring

Maternal folate deficiency affects proliferation, but not apoptosis, in embryonic mouse heart

Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice

Mefolinate (5-methyltetrahydrofolate), but not folic acid, decreases mortality in an animal model of severe methylenetetrahydrofolate reductase deficiency

Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase

Methionine synthase reductase deficiency results in adverse reproductive outcomes and congenital heart defects in mice

Methotrexate-induced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase.

Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid

Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice

Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy ⬇️

Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians

Methylenetetrahydrofolate reductase: a link between folate and riboflavin?

Mice deficient in methylenetetrahydrofolate reductase exhibit tissue-specific distribution of folates

Microarray analysis of brain RNA in mice with methylenetetrahydrofolate reductase deficiency and hyperhomocysteinemia

Mild methylenetetrahydrofolate reductase deficiency alters inflammatory and lipid pathways in liver

Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism