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A multinucleating Escherichia coli cytotoxin perturbs cell cycle in cultured epithelial cells.

artículo científico publicado en 2006

Activation of Rho GTPases triggers structural remodeling and functional plasticity in the adult rat visual cortex

artículo científico publicado en 2011

Activation of rho GTPases by cytotoxic necrotizing factor 1 induces macropinocytosis and scavenging activity in epithelial cells

artículo científico publicado en 2001

Bacterial protein toxins in human cancers.

artículo científico publicado en 2015

Bacterial protein toxins: current and potential clinical use.

artículo científico publicado en 2008

CNF1 improves astrocytic ability to support neuronal growth and differentiation in vitro.

artículo científico publicado en 2012

Cell Propagation of Cholera Toxin CTA ADP-Ribosylating Factor by Exosome Mediated Transfer.

artículo científico publicado en 2018

Cell-to-cell propagation of the bacterial toxin CNF1 via extracellular vesicles: potential impact on the therapeutic use of the toxin.

artículo científico publicado en 2015

Clostridium difficile toxin B causes apoptosis in epithelial cells by thrilling mitochondria. Involvement of ATP-sensitive mitochondrial potassium channels.

artículo científico publicado en 2007

Clostridium difficile toxin B induces apoptosis in intestinal cultured cells

artículo científico publicado en 1998

Cnf1 Variants Endowed with the Ability to Cross the Blood-Brain Barrier: A New Potential Therapeutic Strategy for Glioblastoma

scientific article published on 04 May 2020

Cytotoxic necrotizing factor 1 enhances reactive oxygen species-dependent transcription and secretion of proinflammatory cytokines in human uroepithelial cells

artículo científico publicado en 2003

Cytotoxic necrotizing factor 1 hinders skeletal muscle differentiation in vitro by perturbing the activation/deactivation balance of Rho GTPases.

artículo científico publicado en 2005

Effects of the Escherichia coli Bacterial Toxin Cytotoxic Necrotizing Factor 1 on Different Human and Animal Cells: A Systematic Review

artículo científico publicado en 2021

Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function.

artículo científico publicado en 2016

Enhancement of learning and memory after activation of cerebral Rho GTPases

artículo científico publicado en 2007

Enhancement of mitochondrial ATP production by the Escherichia coli cytotoxic necrotizing factor 1.

artículo científico publicado en 2014

Epithelial cells challenged with a Rac-activating E. coli cytotoxin acquire features of professional phagocytes.

artículo científico publicado en 2002

Escherichia coli cytotoxic necrotizing factor 1 blocks cell cycle G2/M transition in uroepithelial cells

artículo científico publicado en 2006

Extracts from Cell Suspension Cultures of Strawberry (Fragaria x ananassa Duch): Cytotoxic Effects on Human Cancer Cells

artículo científico publicado en 2019

Eye Drop Instillation of the Rac1 Modulator CNF1 Attenuates Retinal Gliosis and Ameliorates Visual Performance in a Rat Model of Hypertensive Retinopathy

scientific article published on 23 May 2019

Functional Analyses of the Crohn's Disease Risk Gene LACC1

artículo científico publicado en 2016

Gut Microbiota and Colon Cancer: A Role for Bacterial Protein Toxins?

scientific article published on 27 August 2020

High yield purification and first structural characterization of the full-length bacterial toxin CNF1.

artículo científico publicado en 2017

Hijacking Rho GTPases by protein toxins and apoptosis: molecular strategies of pathogenic bacteria.

artículo científico publicado en 2003

Hinderance of Apoptosis and Phagocytic Behaviour Induced by Escherichia coli Cytotoxic Necrotizing Factor 1: Two Related Activities in Epithelial Cells

artículo científico publicado en 1997

Integrated Cancer Treatment in the Course of Metastatic Pancreatic Cancer: Complete Resolution in 2 Cases

artículo científico publicado en 2018

Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: protective effect of CNF1.

artículo científico publicado en 2015

Modulation of Rho GTPases rescues brain mitochondrial dysfunction, cognitive deficits and aberrant synaptic plasticity in female mice modeling Rett syndrome.

artículo científico publicado en 2015

Modulation of RhoGTPases improves the behavioral phenotype and reverses astrocytic deficits in a mouse model of Rett syndrome.

artículo científico publicado en 2011

Multinucleation and pro-inflammatory cytokine release promoted by fibrous fluoro-edenite in lung epithelial A549 cells

artículo científico publicado en 2006

N -Acetylcysteine protects epithelial cells against the oxidative imbalance due to Clostridium difficile toxins

artículo científico publicado en 1999

Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome

artículo científico publicado en 2014

Progression of motor deficits in glioma-bearing mice: impact of CNF1 therapy at symptomatic stages

artículo científico publicado en 2017

Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes

artículo científico publicado en 2003

Rho-activating Escherichia coli cytotoxic necrotizing factor 1: macropinocytosis of apoptotic bodies in human epithelial cells.

artículo científico publicado en 2002

The 5' region of cnf1 harbours a translational regulatory mechanism for CNF1 synthesis and encodes the cell-binding domain of the toxin.

artículo científico publicado en 1999

The Bacterial Protein CNF1 as a Potential Therapeutic Strategy against Mitochondrial Diseases: A Pilot Study

artículo científico publicado en 2018

The Bacterial Toxin CNF1 Induces Activation and Maturation of Human Monocyte-Derived Dendritic Cells.

artículo científico publicado en 2018

The E. coli CNF1 as a pioneering therapy for the central nervous system diseases

artículo científico

The Escherichia coli protein toxin cytotoxic necrotizing factor 1 induces epithelial mesenchymal transition

scientific article published on 15 November 2019

The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating mu-opioid receptors.

artículo científico publicado en 2009

The Rac-activating toxin cytotoxic necrotizing factor 1 oversees NK cell-mediated activity by regulating the actin/microtubule interplay.

artículo científico publicado en 2003

The Rho-activating CNF1 toxin from pathogenic E. coli: a risk factor for human cancer development?

artículo científico publicado en 2008

The bacterial protein toxin, cytotoxic necrotizing factor 1 (CNF1) provides long-term survival in a murine glioma model

artículo científico publicado en 2014

The cytotoxic necrotizing factor 1 from E. coli: a janus toxin playing with cancer regulators.

artículo científico publicado en 2013

The potential role of garlic (Allium sativum) against the multi-drug resistant tuberculosis pandemic: a review

artículo científico publicado el 1 de enero de 2011