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A line before liquor: a novel model of cocaine and alcohol co-abuse reveals changes in glutamate homeostasis

scientific article published on 05 August 2019

A role for corticotropin releasing factor (CRF) in ethanol consumption, sensitivity, and reward as revealed by CRF-deficient mice.

artículo científico publicado en 2002

Abuse liability of novel 'legal high' designer stimulants: evidence from animal models

artículo científico

Acamprosate attenuates cocaine- and cue-induced reinstatement of cocaine-seeking behavior in rats.

artículo científico publicado en 2007

Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors.

artículo científico publicado en 2010

Anxiogenic and aversive effects of corticotropin-releasing factor (CRF) in the bed nucleus of the stria terminalis in the rat: role of CRF receptor subtypes.

artículo científico publicado en 2006

Are AMPA receptor positive allosteric modulators potential pharmacotherapeutics for addiction?

artículo científico publicado en 2013

Attenuation of cocaine-induced reinstatement of cocaine conditioned place preference by acamprosate.

artículo científico publicado en 2006

Attenuation of methamphetamine seeking by the mGluR2/3 agonist LY379268 in rats with histories of restricted and escalated self-administration

artículo científico publicado el 31 de mayo de 2012

Attenuation of reinstatement of methamphetamine-, sucrose-, and food-seeking behavior in rats by fenobam, a metabotropic glutamate receptor 5 negative allosteric modulator

artículo científico publicado el 21 de julio de 2012

Basal total opioid peptide release in the striatum of rats with cholestasis from bile duct resection: a study by the use of in vivo microdialysis.

artículo científico publicado en 1997

Calcium-permeable AMPA receptors and silent synapses in cocaine-conditioned place preference.

artículo científico publicado en 2017

Changes in extracellular levels of glutamate in the nucleus accumbens after ethanol-induced behavioral sensitization in adolescent and adult mice.

artículo científico publicado en 2011

Chronic stress may facilitate the recruitment of habit- and addiction-related neurocircuitries through neuronal restructuring of the striatum.

artículo científico publicado en 2014

Chronic treatment with N-acetylcysteine decreases extinction responding and reduces cue-induced nicotine-seeking

artículo científico publicado en 2019

Chronic variable stress and intravenous methamphetamine self-administration - Role of individual differences in behavioral and physiological reactivity to novelty

artículo científico publicado en 2016

Cognitive deficits and neurotoxicity induced by synthetic cathinones: is there a role for neuroinflammation?

artículo científico publicado en 2018

Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction.

artículo científico publicado en 2010

Combined antiretroviral therapy reduces brain viral load and pathological features of HIV encephalitis in a mouse model.

artículo científico publicado en 2014

DARK Classics in Chemical Neuroscience: Cathinone-Derived Psychostimulants.

artículo científico publicado en 2018

Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.

artículo científico publicado en 2002

Designer drugs - A continuing chemical (R)evolution

artículo científico publicado en 2018

Differential Modulation of Thresholds for Intracranial Self-Stimulation by mGlu5 Positive and Negative Allosteric Modulators: Implications for Effects on Drug Self-Administration.

artículo científico publicado en 2012

Early life stress and chronic variable stress in adulthood interact to influence methamphetamine self-administration in male rats.

artículo científico publicado en 2015

Early-life stress interactions with the epigenome: potential mechanisms driving vulnerability toward psychiatric illness

artículo científico publicado en 2014

Editorial: structural plasticity induced by drugs of abuse

artículo científico publicado en 2015

Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release.

artículo científico publicado en 2002

Effects of heroin on rat prosocial behavior

artículo científico publicado en 2018

Effects of modafinil and R-modafinil on brain stimulation reward thresholds: implications for their use in the treatment of psychostimulant dependence.

artículo científico publicado en 2015

Effects of α-pyrrolidinopentiophenone and 4-methyl-N-ethylcathinone, two synthetic cathinones commonly found in second-generation "bath salts," on intracranial self-stimulation thresholds in rats.

artículo científico publicado en 2014

Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake.

artículo científico publicado en 2002

Enhancement of extinction learning attenuates ethanol-seeking behavior and alters plasticity in the prefrontal cortex.

artículo científico publicado en 2014

Ethanol facilitates glutamatergic transmission to dopamine neurons in the ventral tegmental area

artículo científico publicado en 2008

Ethanol, Glutamate, and the Ventral Tegmental Area—A Commentary on: Ding, Engleman, Rodd, and McBride, “Ethanol Increases Glutamate Neurotransmission in the Posterior Ventral Tegmental Area of Female Wistar Rats”

artículo científico publicado el 17 de abril de 2012

Extinction learning and adult neurogenesis.

artículo científico publicado en 2011

Functional interaction of mGlu5 and NMDA receptors in aversive learning in rats.

artículo científico publicado en 2010

Glutamatergic medications for the treatment of drug and behavioral addictions

artículo científico publicado el 22 de abril de 2011

Increases in Doublecortin Immunoreactivity in the Dentate Gyrus following Extinction of Heroin-Seeking Behavior

artículo científico publicado el 1 de enero de 2012

Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis.

artículo científico publicado en 2010

Interactions between Early Life Stress, Nucleus Accumbens MeCP2 Expression, and Methamphetamine Self-Administration in Male Rats

artículo científico publicado en 2016

Interactions between taurine and ethanol in the central nervous system.

artículo científico publicado en 2002

Intracranial stereotaxic cannulation for development of orthotopic glioblastoma allograft in Sprague-Dawley rats and histoimmunopathological characterization of the brain tumor

scientific article published on 15 August 2007

Loss of object recognition memory produced by extended access to methamphetamine self-administration is reversed by positive allosteric modulation of metabotropic glutamate receptor 5

artículo científico publicado en 2010

Metabotropic glutamate receptor ligands as potential therapeutics for addiction

artículo científico publicado en 2009

Microdialysis in the mouse nucleus accumbens: a method for detection of monoamine and amino acid neurotransmitters with simultaneous assessment of locomotor activity.

artículo científico publicado en 2000

Modulation of extracellular neurotransmitter levels in the nucleus accumbens by a taurine uptake inhibitor

artículo científico publicado en 2000

N-Acetylcysteine reverses cocaine-induced metaplasticity

artículo científico publicado en 2009

NMDA Receptor Modulators in the Treatment of Drug Addiction

artículo científico publicado en 2013

Neurochemical and Neurostructural Plasticity in Alcoholism

artículo científico publicado el 16 de abril de 2012

Neurocognitive dysfunction following repeated binge-like self-administration of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV).

artículo científico publicado en 2017

Neurokinin-1 (NK₁) receptor antagonists as possible therapeutics for psychostimulant use disorders.

artículo científico

Neuropeptide Systems and Schizophrenia

artículo científico publicado el 1 de agosto de 2013

Nicotine-induced behavioral sensitization in an adult rat model of attention deficit/hyperactivity disorder (ADHD).

artículo científico publicado en 2016

Nicotine-induced place conditioning and locomotor activity in an adolescent animal model of attention deficit/hyperactivity disorder (ADHD).

artículo científico publicado en 2015

Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models

artículo científico publicado en 2012

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density

artículo científico publicado en 2016

Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory

artículo científico publicado en 2009

Positive allosteric modulators of type 5 metabotropic glutamate receptors (mGluR5) and their therapeutic potential for the treatment of CNS disorders.

artículo científico publicado en 2011

Positive or negative allosteric modulation of metabotropic glutamate receptor 5 (mGluR5) does not alter expression of behavioral sensitization to methamphetamine.

artículo científico publicado en 2013

Potent rewarding and reinforcing effects of the synthetic cathinone 3,4‐methylenedioxypyrovalerone (MDPV)

artículo científico publicado el 11 de julio de 2012

Preclinical Evidence That 5-HT1B Receptor Agonists Show Promise as Medications for Psychostimulant Use Disorders

artículo científico publicado en 2017

Preface

artículo científico publicado en 2018

Protein kinase C isozymes as regulators of sensitivity to and self-administration of drugs of abuse-studies with genetically modified mice.

artículo científico publicado en 2010

Protein kinase Cɛ activity regulates mGluR5 surface expression in the rat nucleus accumbens.

artículo científico publicado en 2016

Reinforcing Effects of Cathinone NPS in the Intravenous Drug Self-Administration Paradigm

artículo científico publicado en 2016

Reinstatement of ethanol-seeking behavior following intravenous self-administration in Wistar rats.

artículo científico publicado en 2007

Restoration of prosocial behavior in rats after heroin self-administration via chemogenetic activation of the anterior insular cortex

scientific article published on 30 March 2020

Role of protein kinase C epsilon (PKCvarepsilon) in the reduction of ethanol reinforcement due to mGluR5 antagonism in the nucleus accumbens shell.

artículo científico publicado en 2009

Sensitization to the motor stimulant effects of 3,4-methylenedioxypyrovalerone (MDPV) and cross-sensitization to methamphetamine in rats

artículo científico publicado en 2016

Social Influences in Animal Models of Opiate Addiction

artículo científico publicado en 2018

Structural and functional plasticity of dendritic spines - root or result of behavior?

artículo científico publicado en 2016

Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving.

artículo científico publicado en 2013

The Effects of Maternal Separation on Adult Methamphetamine Self-Administration, Extinction, Reinstatement, and MeCP2 Immunoreactivity in the Nucleus Accumbens.

artículo científico publicado en 2013

The Winding Road to Relapse: Forging a New Understanding of Cue-Induced Reinstatement Models and Their Associated Neural Mechanisms

artículo científico publicado en 2018

The anti-relapse compound acamprosate inhibits the development of a conditioned place preference to ethanol and cocaine but not morphine.

artículo científico publicado en 2003

The development of acamprosate as a treatment against alcohol relapse

artículo científico publicado en 2014

The discriminative stimulus properties of self-administered ethanol are mediated by GABA(A) and NMDA receptors in rats.

artículo científico publicado en 2001

The effect of litter separation on methamphetamine-conditioned place preference in post-partum dams.

artículo científico publicado en 2017

The glucocorticoid receptor antagonist mifepristone reduces ethanol intake in rats under limited access conditions.

artículo científico publicado en 2004

The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse.

artículo científico publicado en 2003

The safety of disulfiram for the treatment of alcohol and cocaine dependence in randomized clinical trials: guidance for clinical practice

artículo científico publicado en 2008

Transcriptional profiling of the rat frontal cortex following administration of the mGlu5 receptor antagonists MPEP and MTEP

artículo científico publicado en 2008

Whole-Cell Patch-Clamp Electrophysiology to Study Ionotropic Glutamatergic Receptors and Their Roles in Addiction

scientific article published on 01 January 2019

mGlu receptors and drug addiction.

artículo científico publicado en 2012

mGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats

artículo científico publicado en 2009

mGluR5 positive allosteric modulation and its effects on MK-801 induced set-shifting impairments in a rat operant delayed matching/non-matching-to-sample task

artículo científico publicado en 2014

mGluR5 positive allosteric modulation enhances extinction learning following cocaine self-administration.

artículo científico publicado en 2011

mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning

artículo científico publicado en 2009

mGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol-seeking behavior

artículo científico publicado el 24 de enero de 2012