Lista de obras -

A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation

artículo científico publicado en 2014

Adult resident cardiomyocytes wake up: new axis for cardiac tissue regeneration

artículo científico publicado en 2012

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling

artículo científico publicado en 2015

An essential role for RGS protein/Gαi2 interactions in B lymphocyte-directed cell migration and trafficking

artículo científico publicado en 2015

Analysis of Arrestin Recruitment to Chemokine Receptors by Bioluminescence Resonance Energy Transfer.

artículo científico publicado en 2015

Atomic force and electron microscopic-based study of sarcolemmal surface of living cardiomyocytes unveils unexpected mitochondrial shift in heart failure.

artículo científico publicado en 2014

Atomic force microscopy-single-molecule force spectroscopy unveils GPCR cell surface architecture

artículo científico publicado en 2022

Biased signaling at chemokine receptors

artículo científico publicado en 2015

Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.

artículo científico publicado en 2008

Biophysical properties of cardiomyocyte surface explored by multiparametric AFM.

artículo científico publicado en 2017

CODA-RET reveals functional selectivity as a result of GPCR heteromerization

artículo científico publicado en 2011

Cardiac cAMP: production, hydrolysis, modulation and detection

artículo científico publicado en 2015

Cardiac fibroblasts regulate sympathetic nerve sprouting and neurocardiac synapse stability

artículo científico publicado en 2013

Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor.

artículo científico publicado en 2016

Cardiotoxicity of chemotherapies

artículo científico publicado en 2012

Characterization of humoral immune responses induced by immunization with plasmid DNA expressing HIV-1 Nef accessory protein

artículo científico publicado en 1998

Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction

artículo científico publicado en 2008

Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing

scientific article published on 18 December 2019

Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor.

artículo científico publicado en 2008

Deciphering biased inverse agonism of cangrelor and ticagrelor at P2Y receptor

article

Deciphering biased-agonism complexity reveals a new active AT1 receptor entity.

artículo científico publicado en 2012

Delineating biased ligand efficacy at 7TM receptors from an experimental perspective

artículo científico publicado en 2016

Detecting and imaging protein-protein interactions during G protein-mediated signal transduction in vivo and in situ by using fluorescence-based techniques.

artículo científico publicado en 2006

Differential β₂-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines

artículo científico publicado en 2014

Dosage-dependent regulation of cell proliferation and adhesion through dual β2-adrenergic receptor/cAMP signals.

artículo científico publicado en 2013

Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling

artículo científico publicado en 2015

Ephrin-B1 is a novel specific component of the lateral membrane of the cardiomyocyte and is essential for the stability of cardiac tissue architecture cohesion

artículo científico publicado en 2012

Evaluation of upconverting nanoparticles towards heart theranostics

artículo científico publicado en 2019

Evidence for a direct interaction between the penultimate aspartic acid of cholecystokinin and histidine 207, located in the second extracellular loop of the cholecystokinin B receptor

artículo científico publicado en 1999

Exercise training-induced modification in autonomic nervous system: An update for cardiac patients.

artículo científico publicado en 2016

Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation.

artículo científico publicado en 2013

Functional enhancement of AT1R potency in the presence of the TPαR is revealed by a comprehensive 7TM receptor co-expression screen

artículo científico publicado en 2013

Functional selective oxytocin-derived agonists discriminate between individual G protein family subtypes

artículo científico publicado en 2011

Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands.

artículo científico publicado en 2009

G protein-coupled receptors, an unexploited animal toxin targets: Exploration of green mamba venom for novel drug candidates active against adrenoceptors.

artículo científico publicado en 2011

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation.

artículo científico publicado en 2018

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex

artículo científico publicado en 2015

Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity

artículo científico publicado en 2005

Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation.

artículo científico publicado en 2016

Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells.

artículo científico publicado en 2006

High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor.

artículo científico publicado en 2003

High-intensity interval exercise improves vagal tone and decreases arrhythmias in chronic heart failure.

artículo científico publicado en 2013

Homologous regulation of the alpha2C-adrenoceptor subtype in human hepatocarcinoma, HepG2.

artículo científico publicado en 1999

Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors.

artículo científico publicado en 2010

Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies

artículo científico publicado en 2003

Mapping HA-tagged protein at the surface of living cells by atomic force microscopy

artículo científico publicado en 2015

Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling

artículo científico publicado en 2010

Mutation of Asn-391 within the conserved NPXXY motif of the cholecystokinin B receptor abolishes Gq protein activation without affecting its association with the receptor

artículo científico publicado en 2000

Nanoscale structural mapping as a measure of maturation in the murine frontal cortex

artículo científico publicado en 2017

Nouveau dialogue entre récepteurs et protéines G trimériques : « une danse à corps enlacés »

artículo científico publicado en 2007

Partial Agonist and Biased Signaling Properties of the Synthetic Enantiomers J113863/UCB35625 at Chemokine Receptors CCR2 and CCR5.

artículo científico publicado en 2016

Probing heterotrimeric G protein activation: applications to biased ligands.

artículo científico

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

artículo científico publicado en 2006

Real-time monitoring of receptor and G-protein interactions in living cells.

artículo científico publicado en 2005

Role of the ubiquitin-proteasome system in the regulation of P2Y13 receptor expression: impact on hepatic HDL uptake

artículo científico publicado en 2013

Short-term effects of a 3-week interval training program on heart rate variability in chronic heart failure. A randomised controlled trial

artículo científico publicado en 2019

Signaling Properties of Chemerin Receptors CMKLR1, GPR1 and CCRL2.

artículo científico publicado en 2016

Specific interactions between Epac1, β-arrestin2 and PDE4D5 regulate β-adrenergic receptor subtype differential effects on cardiac hypertrophic signaling

artículo científico publicado en 2012

Specific roles of G(i) protein family members revealed by dissecting SST5 coupling in human pituitary cells

artículo científico publicado en 2012

Structural evidence for a new elaborate 3D-organization of the cardiomyocyte lateral membrane in adult mammalian cardiac tissues

scientific article published on 01 May 2019

Structure of cholecystokinin receptor binding sites and mechanism of activation/inactivation by agonists/antagonists.

artículo científico publicado en 2002

The experimental power of FR900359 to study Gq-regulated biological processes

artículo científico publicado en 2015

[Adult cardiomyocytes wake up: a big step towards cardiac regeneration].

artículo científico publicado en 2013

[G-protein-coupled receptors plasticity and signalling].

artículo científico publicado en 2012

alpha(2B)-Adrenergic receptors activate MAPK and modulate proliferation of primary cultured proximal tubule cells.

artículo científico publicado en 2002

Lista de obras de

A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation

Adult resident cardiomyocytes wake up: new axis for cardiac tissue regeneration

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling

An essential role for RGS protein/Gαi2 interactions in B lymphocyte-directed cell migration and trafficking

Analysis of Arrestin Recruitment to Chemokine Receptors by Bioluminescence Resonance Energy Transfer.

Atomic force and electron microscopic-based study of sarcolemmal surface of living cardiomyocytes unveils unexpected mitochondrial shift in heart failure.

Atomic force microscopy-single-molecule force spectroscopy unveils GPCR cell surface architecture

Biased signaling at chemokine receptors

Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.

Biophysical properties of cardiomyocyte surface explored by multiparametric AFM.

CODA-RET reveals functional selectivity as a result of GPCR heteromerization

Cardiac cAMP: production, hydrolysis, modulation and detection

Cardiac fibroblasts regulate sympathetic nerve sprouting and neurocardiac synapse stability

Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor.

Cardiotoxicity of chemotherapies

Characterization of humoral immune responses induced by immunization with plasmid DNA expressing HIV-1 Nef accessory protein

Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction

Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing

Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor.

Deciphering biased inverse agonism of cangrelor and ticagrelor at P2Y receptor

Deciphering biased-agonism complexity reveals a new active AT1 receptor entity.

Delineating biased ligand efficacy at 7TM receptors from an experimental perspective

Detecting and imaging protein-protein interactions during G protein-mediated signal transduction in vivo and in situ by using fluorescence-based techniques.

Differential β₂-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines

Dosage-dependent regulation of cell proliferation and adhesion through dual β2-adrenergic receptor/cAMP signals.

Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling

Ephrin-B1 is a novel specific component of the lateral membrane of the cardiomyocyte and is essential for the stability of cardiac tissue architecture cohesion

Evaluation of upconverting nanoparticles towards heart theranostics

Evidence for a direct interaction between the penultimate aspartic acid of cholecystokinin and histidine 207, located in the second extracellular loop of the cholecystokinin B receptor

Exercise training-induced modification in autonomic nervous system: An update for cardiac patients.

Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation.

Functional enhancement of AT1R potency in the presence of the TPαR is revealed by a comprehensive 7TM receptor co-expression screen

Functional selective oxytocin-derived agonists discriminate between individual G protein family subtypes

Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands.

G protein-coupled receptors, an unexploited animal toxin targets: Exploration of green mamba venom for novel drug candidates active against adrenoceptors.

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation.

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex

Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity

Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation.

Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells.

High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor.

High-intensity interval exercise improves vagal tone and decreases arrhythmias in chronic heart failure.

Homologous regulation of the alpha2C-adrenoceptor subtype in human hepatocarcinoma, HepG2.

Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors.

Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies

Mapping HA-tagged protein at the surface of living cells by atomic force microscopy

Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling

Mutation of Asn-391 within the conserved NPXXY motif of the cholecystokinin B receptor abolishes Gq protein activation without affecting its association with the receptor

Nanoscale structural mapping as a measure of maturation in the murine frontal cortex

Nouveau dialogue entre récepteurs et protéines G trimériques : « une danse à corps enlacés »

Partial Agonist and Biased Signaling Properties of the Synthetic Enantiomers J113863/UCB35625 at Chemokine Receptors CCR2 and CCR5.

Probing heterotrimeric G protein activation: applications to biased ligands.

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

Real-time monitoring of receptor and G-protein interactions in living cells.

Role of the ubiquitin-proteasome system in the regulation of P2Y13 receptor expression: impact on hepatic HDL uptake

Short-term effects of a 3-week interval training program on heart rate variability in chronic heart failure. A randomised controlled trial

Signaling Properties of Chemerin Receptors CMKLR1, GPR1 and CCRL2.

Specific interactions between Epac1, β-arrestin2 and PDE4D5 regulate β-adrenergic receptor subtype differential effects on cardiac hypertrophic signaling

Specific roles of G(i) protein family members revealed by dissecting SST5 coupling in human pituitary cells

Structural evidence for a new elaborate 3D-organization of the cardiomyocyte lateral membrane in adult mammalian cardiac tissues

Structure of cholecystokinin receptor binding sites and mechanism of activation/inactivation by agonists/antagonists.

The experimental power of FR900359 to study Gq-regulated biological processes

[Adult cardiomyocytes wake up: a big step towards cardiac regeneration].

[G-protein-coupled receptors plasticity and signalling].

alpha(2B)-Adrenergic receptors activate MAPK and modulate proliferation of primary cultured proximal tubule cells.