Lista de obras -

A cost-effective amino-acid-type selective isotope labeling of proteins expressed in Leishmania tarentolae.

artículo científico publicado en 2009

A-like guanine-guanine stacking in the aqueous DNA duplex of d(GGGGCCCC).

artículo científico publicado en 2001

Advances in the cellular structural biology of nucleic acids

artículo científico publicado en 2018

An A-type double helix of DNA having B-type puckering of the deoxyribose rings.

artículo científico publicado en 2000

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.

artículo científico publicado en 2016

Analysis of binding interfaces of the human scaffold protein AXIN1 by peptide microarrays

scientific article published on 30 August 2018

Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.

artículo científico publicado en 2010

Clustered abasic lesions profoundly change the structure and stability of human telomeric G-quadruplexes.

artículo científico publicado en 2017

Crystal structures of T. brucei MRP1/MRP2 guide-RNA binding complex reveal RNA matchmaking mechanism

artículo científico publicado en 2006

Determination of the glycosidic torsion angles in uniformly 13C-labeled nucleic acids from vicinal coupling constants 3J(C2)/4-H1' and 3J(C6)/8-H1'.

artículo científico publicado en 2002

Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1

artículo científico publicado en 2019

Diverse effects of naturally occurring base lesions on the structure and stability of the human telomere DNA quadruplex.

artículo científico

Evaluating the Effects of the Nonplanarity of Nucleic Acid Bases on NMR, IR, and Vibrational Circular Dichroism Spectra: A Density Functional Theory Computational Study ⬇️

artículo científico publicado el 23 de septiembre de 2010

Evaluation of parameters critical for observing nucleic acids inside living Xenopus laevis oocytes by in-cell NMR spectroscopy.

artículo científico publicado en 2009

Evaluation of stability of DNA i-motifs in the nuclei of living mammalian cells.

artículo científico publicado en 2017

Expression of FGF19 in human embryonic stem cells.

artículo científico publicado en 2013

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

artículo científico publicado en 2019

Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.

artículo científico publicado en 2014

G-quadruplex formation in the Oct4 promoter positively regulates Oct4 expression.

artículo científico publicado en 2016

Guanine bases in DNA G-quadruplex adopt nonplanar geometries owing to solvation and base pairing.

artículo científico publicado en 2012

Impact of nucleic acid self-alignment in a strong magnetic field on the interpretation of indirect spin-spin interactions.

artículo científico publicado en 2015

In-Cell NMR Spectroscopy of Nucleic Acids in Human Cells

scientific article published on 29 November 2018

In-cell NMR and EPR spectroscopy of biomacromolecules

artículo científico publicado en 2014

Indirect NMR Spin−Spin Coupling Constants3J(P,C) and2J(P,H) across the P−O···H−C Link Can Be Used for Structure Determination of Nucleic Acids

artículo científico publicado en 2006

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.

artículo científico publicado en 2017

Instability restricts signaling of multiple fibroblast growth factors.

artículo científico publicado en 2015

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.

artículo científico publicado en 2017

Metabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization

artículo científico publicado en 2017

Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma.

artículo científico publicado en 2016

Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy

artículo científico publicado en 2019

NF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cells

artículo científico publicado en 2010

NMR (13)C-relaxation study of base and sugar dynamics in GCAA RNA hairpin tetraloop.

artículo científico publicado en 2007

NMR Cross-Correlated Relaxation Rates Reveal Ion Coordination Sites in DNA

artículo científico publicado en 2011

Nanodiamonds as “artificial proteins”: Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals

scientific article published on 21 May 2018

Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle.

artículo científico publicado en 2016

One reporter for in-cell activity profiling of majority of protein kinase oncogenes.

scientific article published on 15 February 2017

Pyramidalization of the glycosidic nitrogen provides the way for efficient cleavage of the N-glycosidic bond of 8-OxoG with the hOGG1 DNA repair protein

artículo científico publicado en 2012

Reaction mechanism and stereochemistry of gamma-hexachlorocyclohexane dehydrochlorinase LinA.

artículo científico publicado en 2000

Revisiting the planarity of nucleic acid bases: Pyramidilization at glycosidic nitrogen in purine bases is modulated by orientation of glycosidic torsion.

artículo científico publicado en 2009

Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.

artículo científico publicado en 2004

Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin

artículo científico publicado en 2003

Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from Trypanosoma brucei

artículo científico publicado en 2008

Structure of a Stable G-Hairpin.

artículo científico publicado en 2017

Sugar pucker modulates the cross-correlated relaxation rates across the glycosidic bond in DNA.

artículo científico publicado en 2005

The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling

artículo científico publicado en 2018

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

artículo científico publicado en 2018

The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions.

artículo científico publicado en 2011

Towards characterization of DNA structure under physiological conditions in vivo at the single-molecule level using single-pair FRET ⬇️

artículo científico publicado el 28 de abril de 2012

Unique C. elegans telomeric overhang structures reveal the evolutionarily conserved properties of telomeric DNA

artículo científico publicado en 2015

Lista de obras de

A cost-effective amino-acid-type selective isotope labeling of proteins expressed in Leishmania tarentolae.

A-like guanine-guanine stacking in the aqueous DNA duplex of d(GGGGCCCC).

Advances in the cellular structural biology of nucleic acids

An A-type double helix of DNA having B-type puckering of the deoxyribose rings.

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.

Analysis of binding interfaces of the human scaffold protein AXIN1 by peptide microarrays

Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.

Clustered abasic lesions profoundly change the structure and stability of human telomeric G-quadruplexes.

Crystal structures of T. brucei MRP1/MRP2 guide-RNA binding complex reveal RNA matchmaking mechanism

Determination of the glycosidic torsion angles in uniformly 13C-labeled nucleic acids from vicinal coupling constants 3J(C2)/4-H1' and 3J(C6)/8-H1'.

Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1

Diverse effects of naturally occurring base lesions on the structure and stability of the human telomere DNA quadruplex.

Evaluating the Effects of the Nonplanarity of Nucleic Acid Bases on NMR, IR, and Vibrational Circular Dichroism Spectra: A Density Functional Theory Computational Study ⬇️

Evaluation of parameters critical for observing nucleic acids inside living Xenopus laevis oocytes by in-cell NMR spectroscopy.

Evaluation of stability of DNA i-motifs in the nuclei of living mammalian cells.

Expression of FGF19 in human embryonic stem cells.

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.

G-quadruplex formation in the Oct4 promoter positively regulates Oct4 expression.

Guanine bases in DNA G-quadruplex adopt nonplanar geometries owing to solvation and base pairing.

Impact of nucleic acid self-alignment in a strong magnetic field on the interpretation of indirect spin-spin interactions.

In-Cell NMR Spectroscopy of Nucleic Acids in Human Cells

In-cell NMR and EPR spectroscopy of biomacromolecules

Indirect NMR Spin−Spin Coupling Constants3J(P,C) and2J(P,H) across the P−O···H−C Link Can Be Used for Structure Determination of Nucleic Acids

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.

Instability restricts signaling of multiple fibroblast growth factors.

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.

Metabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization

Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma.

Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy

NF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cells

NMR (13)C-relaxation study of base and sugar dynamics in GCAA RNA hairpin tetraloop.

NMR Cross-Correlated Relaxation Rates Reveal Ion Coordination Sites in DNA

Nanodiamonds as “artificial proteins”: Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals

Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle.

One reporter for in-cell activity profiling of majority of protein kinase oncogenes.

Pyramidalization of the glycosidic nitrogen provides the way for efficient cleavage of the N-glycosidic bond of 8-OxoG with the hOGG1 DNA repair protein

Reaction mechanism and stereochemistry of gamma-hexachlorocyclohexane dehydrochlorinase LinA.

Revisiting the planarity of nucleic acid bases: Pyramidilization at glycosidic nitrogen in purine bases is modulated by orientation of glycosidic torsion.

Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.

Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin

Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from Trypanosoma brucei

Structure of a Stable G-Hairpin.

Sugar pucker modulates the cross-correlated relaxation rates across the glycosidic bond in DNA.

The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions.

Towards characterization of DNA structure under physiological conditions in vivo at the single-molecule level using single-pair FRET ⬇️

Unique C. elegans telomeric overhang structures reveal the evolutionarily conserved properties of telomeric DNA