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A novel tissue-selective β2-adrenoceptor agonist with minimized cardiovascular effects, 5-HOB, attenuates neuropathic pain in mice

artículo científico publicado en 2019

ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments

scientific article published on 26 July 2016

An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy

scientific article published on 02 December 2013

Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis.

artículo científico publicado en 2008

Anti-tumor effect of a novel FAK inhibitor TAE226 against human oral squamous cell carcinoma

artículo científico publicado en 2012

Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism

artículo científico publicado en 2012

Dual tyrosine kinase inhibitor for focal adhesion kinase and insulin-like growth factor-I receptor exhibits anticancer effect in esophageal adenocarcinoma in vitro and in vivo.

artículo científico publicado en 2008

Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival.

artículo científico publicado en 2017

Evaluation of therapeutic effects of FAK inhibition in murine models of atherosclerosis

scientific article published on 02 April 2019

Group IVA phospholipase A2 is associated with the storage of lipids in adipose tissue and liver.

artículo científico publicado en 2008

ICE: a novel and efficient method for isolation of chromosomal ends ⬇️

artículo científico publicado el 1 de julio de 1997

Identification and characterization of a phenyl-thiazolyl-benzoic acid derivative as a novel RAR/RXR agonist

scientific article published on 19 November 2019

Inhibition of focal adhesion kinase as a potential therapeutic strategy for imatinib-resistant gastrointestinal stromal tumor.

artículo científico publicado en 2009

Inhibition of podocyte FAK protects against proteinuria and foot process effacement.

artículo científico publicado en 2010

Mouse models of cancer-induced cachexia: Hind limb muscle mass and evoked force as readouts

artículo científico publicado en 2018

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

artículo científico publicado en 2009

Pharmacological Characterization of a Novel 5-Hydroxybenzothiazolone-Derived β 2-Adrenoceptor Agonist with Functional Selectivity for Anabolic Effects on Skeletal Muscle Resulting in a Wider Cardiovascular Safety Window in Preclinical Studies

artículo científico publicado en 2019

Pharmacological profiling of a dual FAK/IGF-1R kinase inhibitor TAE226 in cellular and in vivo tumor models.

artículo científico publicado en 2019

Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice

scientific article published on 01 October 1999

Shortened telomeres involved in a case with a jumping translocation at 1q21

scientific article published on 01 March 1998

Variant forms of upstream stimulatory factors (USFs) control the promoter activity of hTERT, the human gene encoding the catalytic subunit of telomerase

artículo científico publicado en 2002

YM155, a novel survivin suppressant, enhances taxane-induced apoptosis and tumor regression in a human Calu 6 lung cancer xenograft model ⬇️

artículo científico publicado el 1 de junio de 2011

[Chromosome rearrangement involving telomeres in cancers]

artículo científico publicado en 1998

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