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A New STAT3-binding Partner, ARL3, Enhances the Phosphorylation and Nuclear Accumulation of STAT3.

artículo científico publicado en 2016

A proteolytic C-terminal fragment of Nogo-A (reticulon-4A) is released in exosomes and potently inhibits axon regeneration

scientific article published on 20 November 2019

Adaptor protein STAP-2 modulates cellular signaling in immune systems.

artículo científico

BS69 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation

artículo científico publicado en 2010

CCR7 is involved in BCR-ABL/STAP-2-mediated cell growth in hematopoietic Ba/F3 cells

artículo científico publicado en 2015

Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors.

artículo científico publicado en 2004

DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118.

artículo científico publicado en 2007

Daxx enhances Fas-mediated apoptosis in a murine pro-B cell line, BAF3.

artículo científico publicado en 2003

Determination of the transphosphorylation sites of Jak2 kinase.

artículo científico publicado en 2004

Enhanced c-Fms/M-CSF receptor signaling and wound-healing process in bone marrow-derived macrophages of signal-transducing adaptor protein-2 (STAP-2) deficient mice

scientific article published on 01 September 2008

Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration.

artículo científico publicado en 2018

Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit

artículo científico publicado en 2018

Inhibiting poly(ADP-ribosylation) improves axon regeneration

artículo científico publicado en 2016

Inhibition of Poly-ADP-Ribosylation Fails to Increase Axonal Regeneration or Improve Functional Recovery after Adult Mammalian CNS Injury.

artículo científico publicado en 2016

Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells.

artículo científico publicado en 2010

Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells.

artículo científico publicado en 2011

Involvement of heat-shock protein 90 in the interleukin-6-mediated signaling pathway through STAT3.

artículo científico publicado en 2003

Involvement of tyrosine kinase-2 in both the IL-12/Th1 and IL-23/Th17 axes in vivo.

artículo científico publicado en 2011

KAP1 regulates type I interferon/STAT1-mediated IRF-1 gene expression

artículo científico publicado en 2008

Krüppel-associated box-associated protein 1 negatively regulates TNF-α-induced NF-κB transcriptional activity by influencing the interactions among STAT3, p300, and NF-κB/p65

artículo científico publicado en 2011

Limiting Neuronal Nogo Receptor 1 Signaling during Experimental Autoimmune Encephalomyelitis Preserves Axonal Transport and Abrogates Inflammatory Demyelination

artículo científico publicado en 2019

Molecular interactions between STAT3 and protein inhibitor of activated STAT3, and androgen receptor

artículo científico publicado en 2003

Nuclear retention of STAT3 through the coiled-coil domain regulates its activity.

artículo científico publicado en 2005

PDLIM2 Inhibits T Helper 17 Cell Development and Granulomatous Inflammation Through Degradation of STAT3

artículo científico publicado el 6 de diciembre de 2011

Phosphorylation of threonine-265 in Zipper-interacting protein kinase plays an important role in its activity and is induced by IL-6 family cytokines.

artículo científico publicado en 2005

Physical and functional interactions between Daxx and STAT3

artículo científico publicado en 2006

Physical and functional interactions between STAP-2/BKS and STAT5.

artículo científico publicado en 2004

Physical and functional interactions between STAT3 and KAP1.

artículo científico publicado en 2007

Physical and functional interactions between STAT3 and ZIP kinase

scientific journal article

Plexina2 and CRMP2 Signaling Complex Is Activated by Nogo-A-Liganded Ngr1 to Restrict Corticospinal Axon Sprouting after Trauma

scientific article published on 25 February 2019

Regulation of FcepsilonRI-mediated signaling by an adaptor protein STAP-2/BSK in rat basophilic leukemia RBL-2H3 cells.

artículo científico publicado en 2003

Regulation of STAT3-mediated signaling by LMW-DSP2

artículo científico publicado en 2006

STAP-2 Protein Expression in B16F10 Melanoma Cells Positively Regulates Protein Levels of Tyrosinase, Which Determines Organs to Infiltrate in the Body

artículo científico publicado en 2015

STAP-2 interacts with Pyk2 and enhances Pyk2 activity in T-cells

artículo científico publicado en 2017

STAP-2 interacts with and modulates BCR-ABL-mediated tumorigenesis.

artículo científico publicado en 2012

STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation

scientific journal article

STAP-2 positively regulates FcεRI-mediated basophil activation and basophil-dependent allergic inflammatory reactions

scientific article published on 01 April 2019

STAP-2 protein promotes prostate cancer growth by enhancing epidermal growth factor receptor stabilization.

artículo científico publicado en 2017

Signal-transducing adaptor protein-2 controls the IgE-mediated, mast cell-mediated anaphylactic responses

artículo científico publicado en 2014

Signal-transducing adaptor protein-2 modulates Fas-mediated T cell apoptosis by interacting with caspase-8.

artículo científico publicado en 2012

Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase.

artículo científico publicado en 2007

Signal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis

artículo científico publicado en 2014

Silencing mediator of retinoic acid and thyroid hormone receptor regulates enhanced activation of signal transducer and activator of transcription 3 by epstein-barr virus-derived epstein-barr nuclear antigen 2.

artículo científico publicado en 2009

Sumoylation of Daxx regulates IFN-induced growth suppression of B lymphocytes and the hormone receptor-mediated transactivation.

artículo científico publicado en 2006

Sumoylation of Smad3 stimulates its nuclear export during PIASy-mediated suppression of TGF-beta signaling.

artículo científico publicado en 2008

The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction.

artículo científico publicado en 2008

The Nogo receptor NgR1 mediates infection by mammalian reovirus.

artículo científico publicado en 2014

The exon-junction complex proteins, Y14 and MAGOH regulate STAT3 activation.

artículo científico publicado en 2009

The nociceptin receptor inhibits axonal regeneration and recovery from spinal cord injury.

artículo científico publicado en 2018

The protein content of an adaptor protein, STAP-2 is controlled by E3 ubiquitin ligase Cbl.

artículo científico publicado en 2009

The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival

artículo científico publicado en 2020

Tyk2 deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.

artículo científico publicado en 2011

Tyk2 is a therapeutic target for psoriasis-like skin inflammation.

artículo científico publicado en 2013

Tyrosine kinase 2 interacts with and phosphorylates receptor for activated C kinase-1, a WD motif-containing protein.

artículo científico publicado en 2004

UBE1a Suppresses Herpes Simplex Virus-1 Replication

scientific article published on 04 December 2020

Y14 positively regulates TNF-α-induced NF-κB transcriptional activity via interacting RIP1 and TRADD beyond an exon junction complex protein.

artículo científico publicado en 2013

Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4)

artículo científico publicado en 2011