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A New STAT3-binding Partner, ARL3, Enhances the Phosphorylation and Nuclear Accumulation of STAT3.

artículo científico publicado en 2016

A Novel α9 Integrin Ligand, XCL1/Lymphotactin, Is Involved in the Development of Murine Models of Autoimmune Diseases.

artículo científico publicado en 2017

Anti-IL-17A blocking antibody reduces cyclosporin A-induced relapse in experimental autoimmune encephalomyelitis mice

artículo científico publicado en 2016

BS69 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation

artículo científico publicado en 2010

Biochanin A enhances RORγ activity through STAT3-mediated recruitment of NCOA1.

artículo científico publicado en 2017

CCR7 is involved in BCR-ABL/STAP-2-mediated cell growth in hematopoietic Ba/F3 cells

artículo científico publicado en 2015

Caspase-dependent cleavage regulates protein levels of Epstein-Barr virus-derived latent membrane protein 1.

artículo científico publicado en 2016

Daxx enhances Fas-mediated apoptosis in a murine pro-B cell line, BAF3.

artículo científico publicado en 2003

Design and Synthesis of Cyclopropane Congeners of Resolvin E2, an Endogenous Proresolving Lipid Mediator, as Its Stable Equivalents.

artículo científico publicado en 2016

Dimethyl fumarate dampens IL-17-ACT1-TBK1 axis-mediated phosphorylation of Regnase-1 and suppresses IL-17-induced IκB-ζ expression

artículo científico publicado en 2019

Enhanced c-Fms/M-CSF receptor signaling and wound-healing process in bone marrow-derived macrophages of signal-transducing adaptor protein-2 (STAP-2) deficient mice

scientific article published on 01 September 2008

IL-17A plays a central role in the expression of psoriasis signature genes through the induction of IκB-ζ in keratinocytes.

artículo científico publicado en 2016

Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ.

artículo científico publicado en 2012

Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells.

artículo científico publicado en 2010

Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells.

artículo científico publicado en 2011

Involvement of tyrosine kinase-2 in both the IL-12/Th1 and IL-23/Th17 axes in vivo.

artículo científico publicado en 2011

Isoflavones enhance interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ.

artículo científico publicado en 2015

IκB-ζ Expression Requires Both TYK2/STAT3 Activity and IL-17-Regulated mRNA Stabilization

artículo científico publicado en 2019

Jun activation domain-binding protein 1 (JAB1) is required for the optimal response to interferons.

artículo científico publicado en 2013

KAP1 regulates type I interferon/STAT1-mediated IRF-1 gene expression

artículo científico publicado en 2008

Kaposi's sarcoma-associated herpesvirus-encoded LANA associates with glucocorticoid receptor and enhances its transcriptional activities

artículo científico publicado en 2015

Krüppel-associated box-associated protein 1 negatively regulates TNF-α-induced NF-κB transcriptional activity by influencing the interactions among STAT3, p300, and NF-κB/p65

artículo científico publicado en 2011

Limitin, an interferon-like cytokine, transduces inhibitory signals on B-cell growth through activation of Tyk2, but not Stat1, followed by induction and nuclear translocation of Daxx.

artículo científico publicado en 2003

Noncanonical K27-linked polyubiquitination of TIEG1 regulates Foxp3 expression and tumor growth.

artículo científico publicado en 2011

Nuclear retention of STAT3 through the coiled-coil domain regulates its activity.

artículo científico publicado en 2005

PDLIM2 Inhibits T Helper 17 Cell Development and Granulomatous Inflammation Through Degradation of STAT3

artículo científico publicado el 6 de diciembre de 2011

PML suppresses IL-6-induced STAT3 activation by interfering with STAT3 and HDAC3 interaction.

artículo científico publicado en 2015

Phosphorylation of threonine-265 in Zipper-interacting protein kinase plays an important role in its activity and is induced by IL-6 family cytokines.

artículo científico publicado en 2005

Physical and functional interactions between Daxx and STAT3

artículo científico publicado en 2006

Physical and functional interactions between STAT3 and KAP1.

artículo científico publicado en 2007

Physical and functional interactions between STAT3 and ZIP kinase

scientific journal article

Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3

artículo científico publicado en 2003

STAP-2 Protein Expression in B16F10 Melanoma Cells Positively Regulates Protein Levels of Tyrosinase, Which Determines Organs to Infiltrate in the Body

artículo científico publicado en 2015

STAP-2 interacts with Pyk2 and enhances Pyk2 activity in T-cells

artículo científico publicado en 2017

STAP-2 interacts with and modulates BCR-ABL-mediated tumorigenesis.

artículo científico publicado en 2012

STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation

scientific journal article

STAP-2 protein promotes prostate cancer growth by enhancing epidermal growth factor receptor stabilization.

artículo científico publicado en 2017

Signal-transducing adapter protein-1 is required for maintenance of leukemic stem cells in CML

artículo científico publicado en 2020

Signal-transducing adaptor protein-2 controls the IgE-mediated, mast cell-mediated anaphylactic responses

artículo científico publicado en 2014

Signal-transducing adaptor protein-2 modulates Fas-mediated T cell apoptosis by interacting with caspase-8.

artículo científico publicado en 2012

Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase.

artículo científico publicado en 2007

Signal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis

artículo científico publicado en 2014

Silencing mediator of retinoic acid and thyroid hormone receptor regulates enhanced activation of signal transducer and activator of transcription 3 by epstein-barr virus-derived epstein-barr nuclear antigen 2.

artículo científico publicado en 2009

Sumoylation of Daxx regulates IFN-induced growth suppression of B lymphocytes and the hormone receptor-mediated transactivation.

artículo científico publicado en 2006

Sumoylation of Smad3 stimulates its nuclear export during PIASy-mediated suppression of TGF-beta signaling.

artículo científico publicado en 2008

Synthesis of Chiral cis-Cyclopropane Bearing Indole and Chromone as Potential TNFα Inhibitors

scientific article published on 24 July 2018

The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction.

artículo científico publicado en 2008

The exon-junction complex proteins, Y14 and MAGOH regulate STAT3 activation.

artículo científico publicado en 2009

The novel α4B murine α4 integrin protein splicing variant inhibits α4 protein-dependent cell adhesion.

artículo científico publicado en 2014

The protein content of an adaptor protein, STAP-2 is controlled by E3 ubiquitin ligase Cbl.

artículo científico publicado en 2009

Tyk2 deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.

artículo científico publicado en 2011

Tyk2 is a therapeutic target for psoriasis-like skin inflammation.

artículo científico publicado en 2013

Tyrosine kinase 2 interacts with and phosphorylates receptor for activated C kinase-1, a WD motif-containing protein.

artículo científico publicado en 2004

Y14 positively regulates TNF-α-induced NF-κB transcriptional activity via interacting RIP1 and TRADD beyond an exon junction complex protein.

artículo científico publicado en 2013

Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4)

artículo científico publicado en 2011