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A critical assessment of in vitro tissue models for ADME and drug delivery

artículo científico

Alzheimer's Disease Phenotype or Inflammatory Insult Does Not Alter Function of L-Type Amino Acid Transporter 1 in Mouse Blood-Brain Barrier and Primary Astrocytes

artículo científico publicado en 2018

An improved cell culture model based on 2/4/A1 cell monolayers for studies of intestinal drug transport: characterization of transport routes.

artículo científico publicado en 2003

Correction to "Prediction of Ocular Drug Distribution from Systemic Blood Circulation".

artículo científico publicado en 2017

Disease-Induced Alterations in Brain Drug Transporters in Animal Models of Alzheimer's Disease : Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla.

artículo científico publicado en 2017

Distribution of Small Molecular Weight Drugs into the Porcine Lens: Studies on Imaging Mass Spectrometry, Partition Coefficients, and Implications in Ocular Pharmacokinetics

artículo científico publicado en 2019

Efflux protein expression in human retinal pigment epithelium cell lines.

artículo científico publicado en 2009

Effluxing ABC transporters in human corneal epithelium.

artículo científico publicado en 2010

Esterase activity in porcine and albino rabbit ocular tissues

artículo científico publicado en 2018

Expression, activity and pharmacokinetic impact of ocular transporters

artículo científico publicado en 2017

Genetically Modified Caco-2 Cells With Improved Cytochrome P450 Metabolic Capacity.

artículo científico publicado en 2016

Human corneal cell culture models for drug toxicity studies

artículo científico publicado en 2016

Intracellular PK/PD Relationships of Free and Liposomal Doxorubicin: Quantitative Analyses and PK/PD Modeling.

artículo científico publicado en 2016

Intravitreal Pharmacokinetics in Mice: SPECT/CT Imaging and Scaling to Rabbits and Humans

scientific article published on 03 September 2019

Intravitreal clearance and volume of distribution of compounds in rabbits: In silico prediction and pharmacokinetic simulations for drug development

article

L-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia

scientific article published on 06 September 2019

Monocarboxylate transport in human corneal epithelium and cell lines.

artículo científico publicado en 2009

Ocular pharmacokinetic modeling using corneal absorption and desorption rates from in vitro permeation experiments with cultured corneal epithelial cells

artículo científico publicado en 2003

Pharmacokinetic aspects of retinal drug delivery.

artículo científico publicado en 2016

Prediction of Ocular Drug Distribution from Systemic Blood Circulation

artículo científico publicado en 2015

Prediction of the Corneal Permeability of Drug-Like Compounds

artículo científico publicado en 2010

Role of retinal pigment epithelium permeability in drug transfer between posterior eye segment and systemic blood circulation

scientific article published on 13 August 2019

Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity.

artículo científico publicado en 2004