Lista de obras -

A characterization of cytostatic factor activity from Xenopus eggs and c-mos-transformed cells ⬇️

artículo científico publicado el 1 de julio de 1991

A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics.

artículo científico publicado en 2018

A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages

artículo científico publicado en 2017

ATM requirement in gene expression responses to ionizing radiation in human lymphoblasts and fibroblasts.

artículo científico publicado en 2006

ATM-dependent and -independent gene expression changes in response to oxidative stress, gamma irradiation, and UV irradiation.

artículo científico publicado en 2003

Ability of the c- mos Product to Associate with and Phosphorylate Tubulin ⬇️

artículo científico publicado el 8 de febrero de 1991

An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage

artículo científico publicado en 2002

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

artículo científico publicado en 2003

Analysis of ATP-binding cassette transporter expression in drug-selected cell lines by a microarray dedicated to multidrug resistance.

artículo científico publicado en 2004

Arsenite malignantly transforms human prostate epithelial cells in vitro by gene amplification of mutated KRAS

article

Assessing gene significance from cDNA microarray expression data via mixed models

artículo científico publicado en 2001

Ataxia telangiectasia-mutated dependent DNA damage checkpoint functions regulate gene expression in human fibroblasts.

artículo científico publicado en 2007

BMDExpress 2: Enhanced transcriptomic dose-response analysis workflow

artículo científico publicado en 2019

Blood gene expression profiling of an early acetaminophen response.

artículo científico publicado en 2016

Blood gene expression signatures predict exposure levels.

artículo científico publicado en 2007

Blood transcript immune signatures distinguish a subset of people with elevated serum ALT from others given acetaminophen

artículo científico publicado en 2015

CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data.

artículo científico publicado en 2007

Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14,643.

artículo científico publicado en 2003

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies

artículo científico publicado en 2018

Computational selection of distinct class- and subclass-specific gene expression signatures.

artículo científico publicado en 2002

Consistency of predictive signature genes and classifiers generated using different microarray platforms.

artículo científico publicado en 2010

Correction: Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage.

artículo científico publicado en 2017

DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs.

artículo científico publicado en 2013

DNA damage responses in murine Pre-B cells with genetic deficiencies in damage response genes

artículo científico publicado en 2019

DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

artículo científico publicado en 2008

DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells

scientific article published on January 2008

Deregulation of specific E2F complexes by the v-mos oncogene ⬇️

artículo científico publicado el 26 de junio de 1997

Detection and Prioritization of Developmentally Neurotoxic and/or Neurotoxic Compounds Using Zebrafish

artículo científico publicado en 2019

Development of a Zebrafish S1500+ Sentinel Gene Set for High-Throughput Transcriptomics

artículo científico publicado en 2019

Differential gene expression profiling in whole blood during acute systemic inflammation in lipopolysaccharide-treated rats.

artículo científico publicado en 2005

Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats.

artículo científico publicado en 2005

Extracting gene expression patterns and identifying co-expressed genes from microarray data reveals biologically responsive processes.

artículo científico publicado en 2007

Folate deficiency in normal human fibroblasts leads to altered expression of genes primarily linked to cell signaling, the cytoskeleton and extracellular matrix.

artículo científico publicado en 2007

From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

artículo científico publicado en 2017

Gene expression analysis offers unique advantages to histopathology in liver biopsy evaluations

artículo científico publicado en 2007

Gene expression analysis reveals chemical-specific profiles

artículo científico publicado en 2002

Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases

artículo científico publicado en 2011

Gene expression profiling of rat livers reveals indicators of potential adverse effects.

artículo científico publicado en 2004

Gene expression signatures but not cell cycle checkpoint functions distinguish AT carriers from normal individuals

artículo científico publicado en 2013

Genome-wide small RNA sequencing and gene expression analysis reveals a microRNA profile of cancer susceptibility in ATM-deficient human mammary epithelial cells.

artículo científico publicado en 2013

Genomic indicators in the blood predict drug-induced liver injury.

artículo científico publicado en 2010

Genomic-derived markers for early detection of calcineurin inhibitor immunosuppressant-mediated nephrotoxicity ⬇️

artículo científico publicado el 24 de agosto de 2011

Identification of distinct and common gene expression changes after oxidative stress and gamma and ultraviolet radiation.

artículo científico publicado en 2003

Intersection of toxicogenomics and high throughput screening in the Tox21 program: an NIEHS perspective

artículo científico publicado en 2015

Major carcinogenic pathways identified by gene expression analysis of peritoneal mesotheliomas following chemical treatment in F344 rats.

artículo científico

Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations.

artículo científico publicado en 2002

Microarray data analysis of mouse neoplasia.

artículo científico publicado en 2005

Molecular effects of 1-naphthyl-methylcarbamate and solar radiation exposures on human melanocytes

artículo científico publicado en 2016

Molecular mechanisms of environmental carcinogenesis ⬇️

artículo científico publicado el 1 de mayo de 1995

Moving Forward in Human Cancer Risk Assessment ⬇️

artículo científico publicado el 13 de diciembre de 2010

Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses

artículo científico publicado en 2007

Oxidative stress and cell cycle checkpoint function.

artículo científico publicado en 2000

Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.

artículo científico publicado en 2008

Perturbation of microRNAs in Rat Heart during Chronic Doxorubicin Treatment ⬇️

artículo científico publicado el 31 de julio de 2012

Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage

artículo científico publicado en 2017

Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.

artículo científico publicado en 2010

Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here

artículo científico publicado en 2019

Serum starved v-mos-transformed cells are unable to appropriately downregulate cyclins and CDKs ⬇️

artículo científico publicado el 26 de junio de 1997

Standardizing global gene expression analysis between laboratories and across platforms.

artículo científico publicado en 2005

Systematic variation normalization in microarray data to get gene expression comparison unbiased.

artículo científico publicado en 2005

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

artículo científico publicado en 2010

The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling

artículo científico publicado en 2019

The US Federal Tox21 Program: A strategic and operational plan for continued leadership.

artículo científico publicado en 2018

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

artículo científico publicado en 2014

The human decatenation checkpoint.

artículo científico publicado en 2001

Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

artículo científico publicado en 2017

Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human relevance

article

Use of transcriptomics in understanding mechanisms of drug-induced toxicity

artículo científico publicado en 2010

pp39mos is associated with p34cdc2 kinase in c-mosxe-transformed NIH 3T3 cells ⬇️

artículo científico publicado el 1 de agosto de 1992

Lista de obras de

A characterization of cytostatic factor activity from Xenopus eggs and c-mos-transformed cells ⬇️

A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics.

A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages

ATM requirement in gene expression responses to ionizing radiation in human lymphoblasts and fibroblasts.

ATM-dependent and -independent gene expression changes in response to oxidative stress, gamma irradiation, and UV irradiation.

Ability of the c- mos Product to Associate with and Phosphorylate Tubulin ⬇️

An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

Analysis of ATP-binding cassette transporter expression in drug-selected cell lines by a microarray dedicated to multidrug resistance.

Arsenite malignantly transforms human prostate epithelial cells in vitro by gene amplification of mutated KRAS

Assessing gene significance from cDNA microarray expression data via mixed models

Ataxia telangiectasia-mutated dependent DNA damage checkpoint functions regulate gene expression in human fibroblasts.

BMDExpress 2: Enhanced transcriptomic dose-response analysis workflow

Blood gene expression profiling of an early acetaminophen response.

Blood gene expression signatures predict exposure levels.

Blood transcript immune signatures distinguish a subset of people with elevated serum ALT from others given acetaminophen

CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data.

Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14,643.

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies

Computational selection of distinct class- and subclass-specific gene expression signatures.

Consistency of predictive signature genes and classifiers generated using different microarray platforms.

Correction: Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage.

DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs.

DNA damage responses in murine Pre-B cells with genetic deficiencies in damage response genes

DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells

Deregulation of specific E2F complexes by the v-mos oncogene ⬇️

Detection and Prioritization of Developmentally Neurotoxic and/or Neurotoxic Compounds Using Zebrafish

Development of a Zebrafish S1500+ Sentinel Gene Set for High-Throughput Transcriptomics

Differential gene expression profiling in whole blood during acute systemic inflammation in lipopolysaccharide-treated rats.

Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats.

Extracting gene expression patterns and identifying co-expressed genes from microarray data reveals biologically responsive processes.

Folate deficiency in normal human fibroblasts leads to altered expression of genes primarily linked to cell signaling, the cytoskeleton and extracellular matrix.

From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

Gene expression analysis offers unique advantages to histopathology in liver biopsy evaluations

Gene expression analysis reveals chemical-specific profiles

Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases

Gene expression profiling of rat livers reveals indicators of potential adverse effects.

Gene expression signatures but not cell cycle checkpoint functions distinguish AT carriers from normal individuals

Genome-wide small RNA sequencing and gene expression analysis reveals a microRNA profile of cancer susceptibility in ATM-deficient human mammary epithelial cells.

Genomic indicators in the blood predict drug-induced liver injury.

Genomic-derived markers for early detection of calcineurin inhibitor immunosuppressant-mediated nephrotoxicity ⬇️

Identification of distinct and common gene expression changes after oxidative stress and gamma and ultraviolet radiation.

Intersection of toxicogenomics and high throughput screening in the Tox21 program: an NIEHS perspective

Major carcinogenic pathways identified by gene expression analysis of peritoneal mesotheliomas following chemical treatment in F344 rats.

Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations.

Microarray data analysis of mouse neoplasia.

Molecular effects of 1-naphthyl-methylcarbamate and solar radiation exposures on human melanocytes

Molecular mechanisms of environmental carcinogenesis ⬇️

Moving Forward in Human Cancer Risk Assessment ⬇️

Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses

Oxidative stress and cell cycle checkpoint function.

Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.

Perturbation of microRNAs in Rat Heart during Chronic Doxorubicin Treatment ⬇️

Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage

Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.

Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here

Serum starved v-mos-transformed cells are unable to appropriately downregulate cyclins and CDKs ⬇️

Standardizing global gene expression analysis between laboratories and across platforms.

Systematic variation normalization in microarray data to get gene expression comparison unbiased.

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling

The US Federal Tox21 Program: A strategic and operational plan for continued leadership.

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

The human decatenation checkpoint.

Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human relevance

Use of transcriptomics in understanding mechanisms of drug-induced toxicity

pp39mos is associated with p34cdc2 kinase in c-mosxe-transformed NIH 3T3 cells ⬇️