Lista de obras -

1,5-Lactamized sialyl acceptors for various disialoside syntheses: novel method for the synthesis of glycan portions of Hp-s6 and HLG-2 gangliosides

scientific article published on 01 October 2005

A 5-Ureido-Modified Sialyl Donor: A Tool for the Synthesis of α-Sialosides

scientific article published on 03 March 2016

A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions.

artículo científico publicado en 2016

A facile method for beta-selenoglycoside synthesis using beta-p-methylbenzoyl selenoglycoside as the selenating unit.

artículo científico publicado en 2005

A first total synthesis of a hybrid-type ganglioside associated with amyotrophic lateral sclerosis-like disorder

scientific article published on 05 November 2010

A first total synthesis of ganglioside HLG-2

artículo científico publicado en 2009

A new chemical approach to human ABO histo-blood group type 2 antigens.

artículo científico publicado en 2013

A synthetic approach to the c-series gangliosides containing sialyl-alpha(2-->8)sialyl-alpha(2-->8)sialic acid: synthesis of ganglioside GT4, alpha(2-->6) GT4 and GT3

artículo científico publicado en 1997

CD22-Antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold ⬇️

artículo científico publicado el 2 de febrero de 2011

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice

artículo científico publicado en 2018

Constrained sialic acid donors enable selective synthesis of α-glycosides

scientific article published on 01 May 2019

Design and synthesis of a novel ganglioside ligand for influenza A viruses.

artículo científico publicado en 2012

Development of Fluorescently Labeled SSEA-3, SSEA-4, and Globo-H Glycosphingolipids for Elucidating Molecular Interactions in the Cell Membrane ⬇️

artículo científico

Development of new ganglioside probes and unraveling of raft domain structure by single-molecule imaging.

artículo científico publicado en 2017

Di-tert-butylsilylene-directed alpha-selective synthesis of 4-methylumbelliferyl T-antigen

scientific article published on 01 September 2005

Efficient Synthesis of the Lewis A Tandem Repeat.

artículo científico publicado en 2016

Efficient diversification of GM3 gangliosides via late-stage sialylation and dynamic glycan structural studies with 19F solid-state NMR

scientific article published on 01 April 2020

Efficiently synthesizing lacto-ganglio-series gangliosides by using a glucosyl ceramide cassette approach: the total synthesis of ganglioside X2

artículo científico publicado en 2012

Expanded potential of seleno-carbohydrates as a molecular tool for X-ray structural determination of a carbohydrate-protein complex with single/multi-wavelength anomalous dispersion phasing

artículo científico publicado en 2014

Extended applications of di-tert-butylsilylene-directed alpha-predominant galactosylation compatible with C2-participating groups toward the assembly of various glycosides

artículo científico publicado en 2006

Extending the glucosyl ceramide cassette approach: application in the total synthesis of ganglioside GalNAc-GM1b.

artículo científico publicado en 2013

First synthesis of a pentasaccharide moiety of ganglioside GAA-7 containing unusually modified sialic acids through the use of N-Troc-sialic acid derivative as a key unit

artículo científico publicado en 2012

Indirect synthetic route to α-l-fucosides via highly stereoselective construction of α-l-galactosides followed by C6-deoxygenation

artículo científico publicado en 2020

Interaction of platelet endothelial cell adhesion molecule (PECAM) with α2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role

artículo científico publicado en 2014

J(77 Se,1 H) and J(77 Se,13 C) couplings of seleno-carbohydrates obtained by 77 Se satellite 1D 13 C spectroscopy and 77 Se selective HR-HMBC spectroscopy

artículo científico publicado en 2018

Linear synthesis of the Chol-1 ganglioside core tetrasaccharide and disialyl T antigen glycan using a 5-ureido-sialyl donor

artículo científico publicado en 2017

On-Membrane Dynamic Interplay between Anti-GM1 IgG Antibodies and Complement Component C1q

artículo científico publicado en 2019

Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions.

artículo científico publicado en 2017

Raft-based interactions of gangliosides with a GPI-anchored receptor

artículo científico publicado en 2016

Renewed synthetic approach to gangliosides exploiting versatile and powerful synthetic units.

artículo científico publicado en 2010

Revealing the Raft Domain Organization in the Plasma Membrane by Single-Molecule Imaging of Fluorescent Ganglioside Analogs.

artículo científico publicado en 2017

Sialyl LewisX mimic-decorated liposomes for anti-angiogenic everolimus delivery to E-selectin expressing endothelial cells

artículo científico publicado en 2019

Six independent fucose-binding sites in the crystal structure of Aspergillus oryzae lectin

artículo científico publicado en 2016

Solid-Phase Capture-Release Strategy Applied to Oligosaccharide Synthesis on a Soluble Polymer Support This work was supported in part by the Mizutani Foundation for Glycoscience (grant to Y.I.), the RIKEN Presidential Fund (grant to S.M.), and the

article published in 2001

Stereoselective Synthesis of Diglycosyl Diacylglycerols with Glycosyl Donors Bearing a β-Stereodirecting 2,3-Naphthalenedimethyl Protecting Group

artículo científico publicado en 2020

Structure-Activity Relationship Study of the Neuritogenic Potential of the Glycan of Starfish Ganglioside LLG-3 (‡).

artículo científico publicado en 2015

Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection

artículo científico publicado en 2012

Studies on the alpha-(1-->4)- and alpha-(1-->8)-fucosylation of sialic acid for the total assembly of the glycan portions of complex HPG-series gangliosides

artículo científico publicado en 2006

Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates.

artículo científico publicado en 2009

Syntheses of Fluorescent Gangliosides for the Studies of Raft Domains.

artículo científico publicado en 2017

Synthesis and Functional Characterization of Novel Sialyl LewisX Mimic-Decorated Liposomes for E-selectin-Mediated Targeting to Inflamed Endothelial Cells

artículo científico publicado en 2017

Synthesis and Glycan-Protein Interaction Studies of Se-Sialosides by 77Se NMR

artículo científico publicado en 2019

Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems

artículo científico publicado en 2014

Synthesis of a novel asparagine-linked heptasaccharide structure via p-methoxybenzyl-assisted beta-mannosylation

scientific article published on 01 September 2000

Synthesis of novel selenapenams, selenacephems, and selenazepines using a 2-(trimethylsilyl)ethyl protection approach.

artículo científico publicado en 2007

Synthesis of seleno-fucose compounds and their application to the X-ray structural determination of carbohydrate-lectin complexes using single/multi-wavelength anomalous dispersion phasing.

artículo científico publicado en 2016

Synthesis of the disialic acid-embedded glycan part of ganglioside HPG-1

artículo científico publicado en 2011

Synthesis of the glycan moiety of ganglioside HPG-7 with an unusual trimer of sialic acid as the inner sugar residue

artículo científico publicado en 2011

Synthetic approach toward complexity of sialic acid-containing glycans

artículo científico publicado en 2014

The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo.

artículo científico publicado en 2016

The Origin of High Stereoselectivity in Di-tert-butylsilylene-Directed α-Galactosylation

artículo científico publicado en 2016

The Total Synthesis of Starfish Ganglioside GP3 Bearing a Unique Sialyl Glycan Architecture

artículo científico publicado en 2016

The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin

artículo científico publicado en 2001

The total synthesis of the neurogenic ganglioside LLG-3 isolated from the starfish Linckia laevigata.

artículo científico publicado en 2011

Total Synthesis of Sialyl Inositol Phosphosphingolipids CJP-2, CJP-3, and CJP-4 Isolated from Feather Star Comanthus japonica

artículo científico publicado en 2019

Total syntheses of disulphated glycosphingolipid SB1a and the related monosulphated SM1a.

artículo científico publicado en 2015

Unraveling of Lipid Raft Organization in Cell Plasma Membranes by Single-Molecule Imaging of Ganglioside Probes

artículo científico publicado en 2018

p- tert-Butyl Groups Improve the Utility of Aromatic Protecting Groups in Carbohydrate Synthesis

scientific article published on 30 May 2019

Lista de obras de

1,5-Lactamized sialyl acceptors for various disialoside syntheses: novel method for the synthesis of glycan portions of Hp-s6 and HLG-2 gangliosides

A 5-Ureido-Modified Sialyl Donor: A Tool for the Synthesis of α-Sialosides

A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions.

A facile method for beta-selenoglycoside synthesis using beta-p-methylbenzoyl selenoglycoside as the selenating unit.

A first total synthesis of a hybrid-type ganglioside associated with amyotrophic lateral sclerosis-like disorder

A first total synthesis of ganglioside HLG-2

A new chemical approach to human ABO histo-blood group type 2 antigens.

A synthetic approach to the c-series gangliosides containing sialyl-alpha(2-->8)sialyl-alpha(2-->8)sialic acid: synthesis of ganglioside GT4, alpha(2-->6) GT4 and GT3

CD22-Antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold ⬇️

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice

Constrained sialic acid donors enable selective synthesis of α-glycosides

Design and synthesis of a novel ganglioside ligand for influenza A viruses.

Development of Fluorescently Labeled SSEA-3, SSEA-4, and Globo-H Glycosphingolipids for Elucidating Molecular Interactions in the Cell Membrane ⬇️

Development of new ganglioside probes and unraveling of raft domain structure by single-molecule imaging.

Di-tert-butylsilylene-directed alpha-selective synthesis of 4-methylumbelliferyl T-antigen

Efficient Synthesis of the Lewis A Tandem Repeat.

Efficient diversification of GM3 gangliosides via late-stage sialylation and dynamic glycan structural studies with 19F solid-state NMR

Efficiently synthesizing lacto-ganglio-series gangliosides by using a glucosyl ceramide cassette approach: the total synthesis of ganglioside X2

Expanded potential of seleno-carbohydrates as a molecular tool for X-ray structural determination of a carbohydrate-protein complex with single/multi-wavelength anomalous dispersion phasing

Extended applications of di-tert-butylsilylene-directed alpha-predominant galactosylation compatible with C2-participating groups toward the assembly of various glycosides

Extending the glucosyl ceramide cassette approach: application in the total synthesis of ganglioside GalNAc-GM1b.

First synthesis of a pentasaccharide moiety of ganglioside GAA-7 containing unusually modified sialic acids through the use of N-Troc-sialic acid derivative as a key unit

Indirect synthetic route to α-l-fucosides via highly stereoselective construction of α-l-galactosides followed by C6-deoxygenation

Interaction of platelet endothelial cell adhesion molecule (PECAM) with α2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role

J(77 Se,1 H) and J(77 Se,13 C) couplings of seleno-carbohydrates obtained by 77 Se satellite 1D 13 C spectroscopy and 77 Se selective HR-HMBC spectroscopy

Linear synthesis of the Chol-1 ganglioside core tetrasaccharide and disialyl T antigen glycan using a 5-ureido-sialyl donor

On-Membrane Dynamic Interplay between Anti-GM1 IgG Antibodies and Complement Component C1q

Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions.

Raft-based interactions of gangliosides with a GPI-anchored receptor

Renewed synthetic approach to gangliosides exploiting versatile and powerful synthetic units.

Revealing the Raft Domain Organization in the Plasma Membrane by Single-Molecule Imaging of Fluorescent Ganglioside Analogs.

Sialyl LewisX mimic-decorated liposomes for anti-angiogenic everolimus delivery to E-selectin expressing endothelial cells

Six independent fucose-binding sites in the crystal structure of Aspergillus oryzae lectin

Solid-Phase Capture-Release Strategy Applied to Oligosaccharide Synthesis on a Soluble Polymer Support This work was supported in part by the Mizutani Foundation for Glycoscience (grant to Y.I.), the RIKEN Presidential Fund (grant to S.M.), and the

Stereoselective Synthesis of Diglycosyl Diacylglycerols with Glycosyl Donors Bearing a β-Stereodirecting 2,3-Naphthalenedimethyl Protecting Group

Structure-Activity Relationship Study of the Neuritogenic Potential of the Glycan of Starfish Ganglioside LLG-3 (‡).

Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection

Studies on the alpha-(1-->4)- and alpha-(1-->8)-fucosylation of sialic acid for the total assembly of the glycan portions of complex HPG-series gangliosides

Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates.

Syntheses of Fluorescent Gangliosides for the Studies of Raft Domains.

Synthesis and Functional Characterization of Novel Sialyl LewisX Mimic-Decorated Liposomes for E-selectin-Mediated Targeting to Inflamed Endothelial Cells

Synthesis and Glycan-Protein Interaction Studies of Se-Sialosides by 77Se NMR

Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems

Synthesis of a novel asparagine-linked heptasaccharide structure via p-methoxybenzyl-assisted beta-mannosylation

Synthesis of novel selenapenams, selenacephems, and selenazepines using a 2-(trimethylsilyl)ethyl protection approach.

Synthesis of seleno-fucose compounds and their application to the X-ray structural determination of carbohydrate-lectin complexes using single/multi-wavelength anomalous dispersion phasing.

Synthesis of the disialic acid-embedded glycan part of ganglioside HPG-1

Synthesis of the glycan moiety of ganglioside HPG-7 with an unusual trimer of sialic acid as the inner sugar residue

Synthetic approach toward complexity of sialic acid-containing glycans

The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo.

The Origin of High Stereoselectivity in Di-tert-butylsilylene-Directed α-Galactosylation

The Total Synthesis of Starfish Ganglioside GP3 Bearing a Unique Sialyl Glycan Architecture

The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin

The total synthesis of the neurogenic ganglioside LLG-3 isolated from the starfish Linckia laevigata.

Total Synthesis of Sialyl Inositol Phosphosphingolipids CJP-2, CJP-3, and CJP-4 Isolated from Feather Star Comanthus japonica

Total syntheses of disulphated glycosphingolipid SB1a and the related monosulphated SM1a.

Unraveling of Lipid Raft Organization in Cell Plasma Membranes by Single-Molecule Imaging of Ganglioside Probes

p- tert-Butyl Groups Improve the Utility of Aromatic Protecting Groups in Carbohydrate Synthesis