Lista de obras -

5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.

artículo científico publicado en 2004

A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver

artículo científico publicado en 2014

A Novel Serum Metabolomic Profile for the Differential Diagnosis of Distal Cholangiocarcinoma and Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2020

A phosphatidylinositol-linkage-deficient T-cell mutant contains insulin-sensitive glycosyl-phosphatidylinositol ⬇️

artículo científico publicado el 15 de marzo de 1992

Altered processing of precursor transcripts and increased levels of the subunit I of mitochondrial cytochrome c oxidase in Syrian hamster fetal cells initiated with ionizing radiation ⬇️

artículo científico publicado el 1 de agosto de 1997

Amphiregulin

artículo científico

Amphiregulin Aggravates Glomerulonephritis via Recruitment and Activation of Myeloid Cells

artículo científico publicado en 2020

Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells.

artículo científico publicado en 2006

Amphiregulin: a new growth factor in hepatocarcinogenesis.

artículo científico publicado en 2007

Amphiregulin: an early trigger of liver regeneration in mice.

artículo científico publicado en 2005

Authors' response: observations suggesting bioactive Fgf15 is not present in mouse blood.

artículo científico publicado en 2013

Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications.

artículo científico publicado en 2017

Chromatin dynamics during liver regeneration

scientific article published on 09 April 2019

Current and innovative emerging therapies for porphyrias with hepatic involvement

artículo científico publicado en 2019

DNA Methylation Regulates a Set of Long Non-Coding RNAs Compromising Hepatic Identity during Hepatocarcinogenesis

artículo científico publicado en 2022

DNA methylation and histone acetylation of rat methionine adenosyltransferase 1A and 2A genes is tissue-specific

artículo científico publicado en 2000

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

artículo científico publicado en 2019

Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells.

artículo científico publicado en 2006

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

artículo científico publicado en 2017

Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis

artículo científico publicado en 2020

Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma

scientific article published on 04 January 2019

Emerging therapies for acute intermittent porphyria.

artículo científico publicado en 2016

Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice

artículo científico publicado en 2017

Enoxaparin reduces hepatic vascular resistance and portal pressure in cirrhotic rats

artículo científico publicado en 2015

Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer.

artículo científico

Epidermal growth factor receptor signaling in hepatocellular carcinoma: inflammatory activation and a new intracellular regulatory mechanism.

artículo científico publicado en 2012

Epigenetic Mechanisms in Gastric Cancer: Potential New Therapeutic Opportunities

artículo científico publicado en 2020

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

scientific article published on 11 February 2019

Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis

artículo científico publicado en 2020

Epigenetics in Liver Fibrosis: Could HDACs be a Therapeutic Target?

artículo científico publicado en 2020

FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted

artículo científico publicado en 2021

Fibroblast Growth Factor 15/19 in Hepatocarcinogenesis.

artículo científico publicado en 2017

Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration

artículo científico publicado en 2017

Fibroblast growth factors 19 and 21 in acute liver damage.

artículo científico publicado en 2018

Further evidence on the janus-faced nature of the epidermal growth factor receptor: From liver regeneration to hepatocarcinogenesis.

artículo científico publicado en 2015

GARBAN: genomic analysis and rapid biological annotation of cDNA microarray and proteomic data.

artículo científico publicado en 2003

Glycosyl-phosphatidylinositol/inositol phosphoglycan: a signaling system for the low-affinity nerve growth factor receptor ⬇️

artículo científico publicado el 15 de septiembre de 1991

Gut roundtable meeting paper: selected recent advances in hepatocellular carcinoma.

artículo científico publicado en 2017

Hepatitis B virus x protein and pin1 in liver cancer: "les liaisons dangereuses".

artículo científico publicado en 2007

Hepatocellular Carcinoma: Updates in Pathogenesis, Detection and Treatment

scientific article published on 23 September 2020

Hepatocyte growth factor induces MAT2A expression and histone acetylation in rat hepatocytes: role in liver regeneration

scientific article published on 01 May 2001

Identification of argininosuccinate lyase as a hypoxia-responsive gene in rat hepatocytes

scientific journal article

Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development

artículo científico publicado en 2014

Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A.

artículo científico publicado en 2004

Impairment of pre-mRNA splicing in liver disease: mechanisms and consequences.

artículo científico publicado en 2010

Induction of TIMP-1 expression in rat hepatic stellate cells and hepatocytes: a new role for homocysteine in liver fibrosis

scientific article published on 01 September 1999

Influence of impaired liver methionine metabolism on the development of vascular disease and inflammation.

artículo científico publicado en 2005

Inhibiting Cytokinesis in the Liver: A New Way to Reduce Tumor Development.

artículo científico publicado en 2018

Inhibition of liver methionine adenosyltransferase gene expression by 3-methylcolanthrene: protective effect of S-adenosylmethionine.

artículo científico publicado en 2001

Insulin-Like Effects of Inositol Phosphate-Glycan on Messenger RNA Expression in Rat Hepatocytes ⬇️

artículo científico publicado el 1 de agosto de 1991

Interaction of glucocorticoids with FXR/FGF19/FGF21-mediated ileum-liver crosstalk

scientific article published on 06 June 2018

Isolation and characterization of SpTRK, a gene from schizosaccharomyces pombe predicted to encode a K+ transporter protein ⬇️

artículo científico publicado el 8 de agosto de 1995

L-Arginine decreases fluid-percussion injury-induced neuronal nitrotyrosine immunoreactivity in rats.

artículo científico publicado en 2008

LKB1: Controlling Quiescence and Genomic Integrity at Home.

artículo científico publicado en 2018

Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice.

artículo científico publicado en 2011

Liver-specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications for MAT1A silencing during transformation.

artículo científico publicado en 2000

Long distance calling for liver regeneration: Identification of neuroendocrine signalling pathways activated after partial hepatectomy ⬇️

artículo científico publicado el 19 de septiembre de 2010

Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma

artículo científico publicado en 2020

MEF2D Transduces Microenvironment Stimuli to ZEB1 to Promote Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer

artículo científico publicado en 2016

Making sorafenib irresistible: In vivo screening for mechanisms of therapy resistance in hepatocellular carcinoma hits on Mapk14.

artículo científico publicado en 2015

Matrix metalloproteinase 10 contributes to hepatocarcinogenesis in a novel crosstalk with the stromal derived factor 1/C-X-C chemokine receptor 4 axis

artículo científico publicado en 2015

Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair

artículo científico publicado en 2013

Messenger RNA therapy for rare genetic metabolic diseases

artículo científico publicado en 2019

Methylthioadenosine phosphorylase gene expression is impaired in human liver cirrhosis and hepatocarcinoma

artículo científico publicado en 2004

Methylthioadenosine.

artículo científico publicado en 2004

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

artículo científico publicado en 2018

Multi-Omics Integration Highlights the Role of Ubiquitination in CCl<sub>4</sub>-Induced Liver Fibrosis

scientific article published on 27 November 2020

New mechanisms involving the EGFR and FGF15/19 systems in liver regeneration and carcinogenesis.

artículo científico publicado en 2014

New molecular interactions of c-Myc in cholangiocarcinoma may open new therapeutic opportunities.

artículo científico publicado en 2016

New therapies for hepatocellular carcinoma.

artículo científico publicado en 2006

Novel pharmacologic strategies to protect the liver from ischemia-reperfusion injury

scientific article published on 01 January 2008

Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice

artículo científico publicado en 2010

Overexpression of the transcription factor MEF2D in hepatocellular carcinoma sustains malignant character by suppressing G2-M transition genes.

artículo científico publicado en 2014

Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis.

artículo científico publicado en 2005

Physiological and enzymatic alterations in sesame seeds submitted to different osmotic potentials.

artículo científico

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

artículo científico publicado en 2020

Platelet-derived growth factor D: a new player in the complex cross-talk between cholangiocarcinoma cells and cancer-associated fibroblasts.

artículo científico publicado en 2013

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease.

artículo científico publicado en 2016

Prioritizing Popular Proteins in Liver Cancer: Remodelling One-Carbon Metabolism.

artículo científico publicado en 2017

Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF

scientific journal article

Radioembolization of hepatocellular carcinoma activates liver regeneration, induces inflammation and endothelial stress and activates coagulation

artículo científico publicado en 2014

Recent advances in alcohol-related liver disease (ALD): summary of a Gut round table meeting

artículo científico publicado en 2019

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma

scientific article published on 01 December 2000

Regulation by hypoxia of methionine adenosyltransferase activity and gene expression in rat hepatocytes

artículo científico publicado en 1998

Regulation of hepatocyte identity and quiescence.

artículo científico

S-Adenosylmethionine modulates inducible nitric oxide synthase gene expression in rat liver and isolated hepatocytes

scientific article published on 01 December 2001

S-Adenosylmethionine: a control switch that regulates liver function.

artículo científico publicado en 2002

S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

artículo científico publicado en 2002

S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver

scientific journal article

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

artículo científico publicado en 2018

Secretion of neu differentiation factor-like polypeptides by cph-transformed fibroblasts: cloning and characterization of Syrian hamster neuregulin cDNAs.

artículo científico publicado en 1998

Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma and primary sclerosing cholangitis

artículo científico publicado en 2019

Specific interaction of methionine adenosyltransferase with free radicals.

artículo científico publicado en 1998

Splicing alterations contributing to cancer hallmarks in the liver: central role of dedifferentiation and genome instability

artículo científico publicado en 2018

Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins

artículo científico publicado en 2019

Splicing regulator SLU7 is essential for maintaining liver homeostasis

artículo científico publicado en 2014

Splicing regulator SLU7 preserves survival of hepatocellular carcinoma cells and other solid tumors via oncogenic miR-17-92 cluster expression

artículo científico publicado en 2016

Systemic messenger RNA as an etiological treatment for acute intermittent porphyria

article

Targeting CCL2/CCR2 in Tumor-Infiltrating Macrophages: A Tool Emerging Out of the Box Against Hepatocellular Carcinoma

scientific article published on 04 December 2018

The EGFR signalling system in the liver: from hepatoprotection to hepatocarcinogenesis

artículo científico

The FXR-FGF19 Gut-Liver Axis as a Novel "Hepatostat".

artículo científico publicado en 2015

The anticoagulant rivaroxaban lowers portal hypertension in cirrhotic rats mainly by deactivating hepatic stellate cells.

artículo científico publicado en 2017

The epidermal growth factor receptor ligand amphiregulin is a negative regulator of hepatic acute-phase gene expression.

artículo científico publicado en 2009

The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis.

artículo científico publicado en 2008

The epidermal growth factor receptor: a link between inflammation and liver cancer.

scientific article published on 08 May 2009

The response of the hepatocyte to ischemia.

artículo científico publicado en 2007

The search for novel diagnostic and prognostic biomarkers in cholangiocarcinoma

artículo científico publicado en 2017

Toll-like receptor-4 expression by hepatic progenitor cells and biliary epithelial cells in HCV-related chronic liver disease.

artículo científico publicado en 2011

Transformed but not normal hepatocytes express UCP2

scientific article published on 01 November 1998

Up-regulation of the anti-inflammatory adipokine adiponectin in acute liver failure in mice.

artículo científico publicado en 2005

Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes cell dedifferentiation and resistance to chemotherapy.

artículo científico publicado en 2009

delta-9-Tetrahydrocannabinol increases prodynorphin and proenkephalin gene expression in the spinal cord of the rat.

artículo científico publicado en 1997

Lista de obras de

5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.

A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver

A Novel Serum Metabolomic Profile for the Differential Diagnosis of Distal Cholangiocarcinoma and Pancreatic Ductal Adenocarcinoma

A phosphatidylinositol-linkage-deficient T-cell mutant contains insulin-sensitive glycosyl-phosphatidylinositol ⬇️

Altered processing of precursor transcripts and increased levels of the subunit I of mitochondrial cytochrome c oxidase in Syrian hamster fetal cells initiated with ionizing radiation ⬇️

Amphiregulin

Amphiregulin Aggravates Glomerulonephritis via Recruitment and Activation of Myeloid Cells

Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells.

Amphiregulin: a new growth factor in hepatocarcinogenesis.

Amphiregulin: an early trigger of liver regeneration in mice.

Authors' response: observations suggesting bioactive Fgf15 is not present in mouse blood.

Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications.

Chromatin dynamics during liver regeneration

Current and innovative emerging therapies for porphyrias with hepatic involvement

DNA Methylation Regulates a Set of Long Non-Coding RNAs Compromising Hepatic Identity during Hepatocarcinogenesis

DNA methylation and histone acetylation of rat methionine adenosyltransferase 1A and 2A genes is tissue-specific

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells.

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis

Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma

Emerging therapies for acute intermittent porphyria.

Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice

Enoxaparin reduces hepatic vascular resistance and portal pressure in cirrhotic rats

Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer.

Epidermal growth factor receptor signaling in hepatocellular carcinoma: inflammatory activation and a new intracellular regulatory mechanism.

Epigenetic Mechanisms in Gastric Cancer: Potential New Therapeutic Opportunities

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis

Epigenetics in Liver Fibrosis: Could HDACs be a Therapeutic Target?

FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted

Fibroblast Growth Factor 15/19 in Hepatocarcinogenesis.

Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration

Fibroblast growth factors 19 and 21 in acute liver damage.

Further evidence on the janus-faced nature of the epidermal growth factor receptor: From liver regeneration to hepatocarcinogenesis.

GARBAN: genomic analysis and rapid biological annotation of cDNA microarray and proteomic data.

Glycosyl-phosphatidylinositol/inositol phosphoglycan: a signaling system for the low-affinity nerve growth factor receptor ⬇️

Gut roundtable meeting paper: selected recent advances in hepatocellular carcinoma.

Hepatitis B virus x protein and pin1 in liver cancer: "les liaisons dangereuses".

Hepatocellular Carcinoma: Updates in Pathogenesis, Detection and Treatment

Hepatocyte growth factor induces MAT2A expression and histone acetylation in rat hepatocytes: role in liver regeneration

Identification of argininosuccinate lyase as a hypoxia-responsive gene in rat hepatocytes

Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development

Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A.

Impairment of pre-mRNA splicing in liver disease: mechanisms and consequences.

Induction of TIMP-1 expression in rat hepatic stellate cells and hepatocytes: a new role for homocysteine in liver fibrosis

Influence of impaired liver methionine metabolism on the development of vascular disease and inflammation.

Inhibiting Cytokinesis in the Liver: A New Way to Reduce Tumor Development.

Inhibition of liver methionine adenosyltransferase gene expression by 3-methylcolanthrene: protective effect of S-adenosylmethionine.

Insulin-Like Effects of Inositol Phosphate-Glycan on Messenger RNA Expression in Rat Hepatocytes ⬇️

Interaction of glucocorticoids with FXR/FGF19/FGF21-mediated ileum-liver crosstalk

Isolation and characterization of SpTRK, a gene from schizosaccharomyces pombe predicted to encode a K+ transporter protein ⬇️

L-Arginine decreases fluid-percussion injury-induced neuronal nitrotyrosine immunoreactivity in rats.

LKB1: Controlling Quiescence and Genomic Integrity at Home.

Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice.

Liver-specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications for MAT1A silencing during transformation.

Long distance calling for liver regeneration: Identification of neuroendocrine signalling pathways activated after partial hepatectomy ⬇️

Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma

MEF2D Transduces Microenvironment Stimuli to ZEB1 to Promote Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer

Making sorafenib irresistible: In vivo screening for mechanisms of therapy resistance in hepatocellular carcinoma hits on Mapk14.

Matrix metalloproteinase 10 contributes to hepatocarcinogenesis in a novel crosstalk with the stromal derived factor 1/C-X-C chemokine receptor 4 axis

Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair

Messenger RNA therapy for rare genetic metabolic diseases

Methylthioadenosine phosphorylase gene expression is impaired in human liver cirrhosis and hepatocarcinoma

Methylthioadenosine.

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

Multi-Omics Integration Highlights the Role of Ubiquitination in CCl<sub>4</sub>-Induced Liver Fibrosis

New mechanisms involving the EGFR and FGF15/19 systems in liver regeneration and carcinogenesis.

New molecular interactions of c-Myc in cholangiocarcinoma may open new therapeutic opportunities.

New therapies for hepatocellular carcinoma.

Novel pharmacologic strategies to protect the liver from ischemia-reperfusion injury

Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice

Overexpression of the transcription factor MEF2D in hepatocellular carcinoma sustains malignant character by suppressing G2-M transition genes.

Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis.

Physiological and enzymatic alterations in sesame seeds submitted to different osmotic potentials.

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

Platelet-derived growth factor D: a new player in the complex cross-talk between cholangiocarcinoma cells and cancer-associated fibroblasts.

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease.

Prioritizing Popular Proteins in Liver Cancer: Remodelling One-Carbon Metabolism.