Lista de obras - Jan A Ehses - Dominio Público Uruguay

Characterization of the carboxyl-terminal domain of the rat glucose-dependent insulinotropic polypeptide (GIP) receptor. A role for serines 426 and 427 in regulating the rate of internalization

artículo científico publicado en 1999

Cytokine production by islets in health and diabetes: cellular origin, regulation and function.

artículo científico publicado en 2010

Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates

artículo científico publicado en 2016

Dipeptidyl peptidase IV inhibition in animal models of diabetes.

artículo científico publicado en 2003

Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.

artículo científico publicado en 2003

Early reduction of circulating homocysteine levels in Goto–Kakizaki rat, a spontaneous nonobese model of type 2 diabetes

artículo científico publicado en 2011

Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I.

artículo científico publicado en 2009

Glucose-dependent insulinotropic polypeptide (GIP): development of DP IV-resistant analogues with therapeutic potential.

artículo científico publicado en 2003

Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.

artículo científico publicado en 2002

Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase.

artículo científico publicado en 2003

Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis.

artículo científico publicado en 2003

Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes.

artículo científico publicado en 2014

Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto–Kakizaki (GK) rat

artículo científico publicado en 2011

IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.

artículo científico publicado en 2011

IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice

artículo científico publicado en 2014

Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

artículo científico publicado en 2008

Increased number of islet-associated macrophages in type 2 diabetes.

artículo científico publicado en 2007

Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells.

artículo científico publicado en 2007

Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity.

artículo científico publicado en 2013

Insulitis in type 2 diabetes

artículo científico publicado en 2008

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

artículo científico publicado en 2007

Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control

artículo científico publicado en 2018

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.

artículo científico publicado en 2011

Interleukin-6 regulates pancreatic alpha-cell mass expansion

artículo científico publicado en 2008

Is there a role for the adaptive immune system in pancreatic beta cell failure in type 2 diabetes?

artículo científico publicado en 2013

Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat

artículo científico publicado en 2009

Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes.

artículo científico publicado en 2009

Islet inflammation in type 2 diabetes: from metabolic stress to therapy.

artículo científico publicado en 2008

Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets

artículo científico publicado en 2004

Mechanisms of beta-cell death in type 2 diabetes.

artículo científico publicado en 2005

Pancreatic islet inflammation in type 2 diabetes: from alpha and beta cell compensation to dysfunction.

artículo científico publicado en 2009

Regenerating 1 and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats

artículo científico publicado en 2014

Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction

artículo científico publicado en 2013

Role of glucose in chronic desensitization of isolated rat islets and mouse insulinoma (betaTC-3) cells to glucose-dependent insulinotropic polypeptide.

artículo científico publicado en 2000

Susceptibility to Fatty Acid-Induced β-Cell Dysfunction Is Enhanced in Prediabetic Diabetes-Prone BioBreeding Rats: A Potential Link Between β-Cell Lipotoxicity and Islet Inflammation ⬇️

artículo científico publicado el 13 de noviembre de 2012

Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes.

scientific article published on 19 June 2009

TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6

artículo científico publicado en 2014

Targeting 12-lipoxygenase as a novel strategy to combat the effects of inflammation on beta cells in diabetes.

artículo científico publicado en 2014

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

artículo científico publicado en 2010

Toll-like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes

artículo científico

[Interleukin-1 receptor antagonist-treatment of patients with type 2 diabetes]

artículo científico publicado en 2007

Lista de obras de Jan A Ehses

Characterization of the carboxyl-terminal domain of the rat glucose-dependent insulinotropic polypeptide (GIP) receptor. A role for serines 426 and 427 in regulating the rate of internalization

Cytokine production by islets in health and diabetes: cellular origin, regulation and function.

Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates

Dipeptidyl peptidase IV inhibition in animal models of diabetes.

Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.

Early reduction of circulating homocysteine levels in Goto–Kakizaki rat, a spontaneous nonobese model of type 2 diabetes

Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I.

Glucose-dependent insulinotropic polypeptide (GIP): development of DP IV-resistant analogues with therapeutic potential.

Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.

Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase.

Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis.

Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes.

Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto–Kakizaki (GK) rat

IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.

IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice

Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

Increased number of islet-associated macrophages in type 2 diabetes.

Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells.

Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity.

Insulitis in type 2 diabetes

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.

Interleukin-6 regulates pancreatic alpha-cell mass expansion

Is there a role for the adaptive immune system in pancreatic beta cell failure in type 2 diabetes?

Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat

Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes.

Islet inflammation in type 2 diabetes: from metabolic stress to therapy.

Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets

Mechanisms of beta-cell death in type 2 diabetes.

Pancreatic islet inflammation in type 2 diabetes: from alpha and beta cell compensation to dysfunction.

Regenerating 1 and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats

Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction

Role of glucose in chronic desensitization of isolated rat islets and mouse insulinoma (betaTC-3) cells to glucose-dependent insulinotropic polypeptide.

Susceptibility to Fatty Acid-Induced β-Cell Dysfunction Is Enhanced in Prediabetic Diabetes-Prone BioBreeding Rats: A Potential Link Between β-Cell Lipotoxicity and Islet Inflammation ⬇️

Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes.

TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6

Targeting 12-lipoxygenase as a novel strategy to combat the effects of inflammation on beta cells in diabetes.

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

Toll-like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes

[Interleukin-1 receptor antagonist-treatment of patients with type 2 diabetes]