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2-Deoxyribose Deprives Cultured Astrocytes of their Glutathione

artículo científico publicado el 24 de agosto de 2010

3-bromopyruvate inhibits glycolysis, depletes cellular glutathione, and compromises the viability of cultured primary rat astrocytes.

artículo científico publicado en 2014

8-Hydroxy-efavirenz, the primary metabolite of the antiretroviral drug Efavirenz, stimulates the glycolytic flux in cultured rat astrocytes.

artículo científico publicado en 2013

A review of the mechanisms of action of dimethylfumarate in the treatment of psoriasis.

artículo científico publicado en 2018

Accumulation of iron oxide nanoparticles by cultured brain astrocytes.

artículo científico publicado en 2009

Accumulation of iron oxide nanoparticles by cultured primary neurons

artículo científico publicado en 2014

Accumulation of non-transferrin-bound iron by neurons, astrocytes, and microglia.

artículo científico publicado en 2010

Adsorption and reduction of glutathione disulfide on α-Al2O3 nanoparticles: experiments and modeling

artículo científico publicado en 2011

Advanced glycation endproducts change glutathione redox status in SH-SY5Y human neuroblastoma cells by a hydrogen peroxide dependent mechanism.

artículo científico publicado en 2001

Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons

artículo científico publicado el 1 de diciembre de 2001

Anethole dithiolethione, a putative neuroprotectant, increases intracellular and extracellular glutathione levels during starvation of cultured astroglial cells

artículo científico publicado en 1998

Antiretroviral protease inhibitors accelerate glutathione export from viable cultured rat neurons

artículo científico publicado en 2014

Arsenate accumulation and arsenate-induced glutathione export in astrocyte-rich primary cultures.

artículo científico publicado en 2013

Arsenate stimulates glutathione export from viable cultured rat cerebellar granule neurons

artículo científico publicado en 2014

Arsenite stimulates glutathione export and glycolytic flux in viable primary rat brain astrocytes.

artículo científico publicado en 2014

Astrocyte functions in the copper homeostasis of the brain.

artículo científico publicado en 2012

Astrocytes retain their antioxidant capacity into advanced old age.

artículo científico publicado en 2010

Bactericidal activity of partially oxidized nanodiamonds.

artículo científico publicado en 2014

Bifunctional submicron colloidosomes coassembled from fluorescent and superparamagnetic nanoparticles

artículo científico publicado en 2014

Catalase in astroglia-rich primary cultures from rat brain: immunocytochemical localization and inactivation during the disposal of hydrogen peroxide.

artículo científico publicado en 2001

Characterisation and metabolism of astroglia-rich primary cultures from cathepsin K-deficient mice.

artículo científico publicado en 2012

Characterization of Arsenate Uptake by Cultured Primary Rat Astrocytes

artículo científico publicado el 1 de junio de 2013

Comparison of primary and secondary rat astrocyte cultures regarding glucose and glutathione metabolism and the accumulation of iron oxide nanoparticles

artículo científico publicado en 2013

Consequences of a Chronic Exposure of Cultured Brain Astrocytes to the Anti-Retroviral Drug Efavirenz and its Primary Metabolite 8-Hydroxy Efavirenz.

artículo científico publicado en 2016

Consequences of a Metabolic Glucose-Depletion on the Survival and the Metabolism of Cultured Rat Astrocytes

scientific article published on 20 February 2019

Copper accelerates glycolytic flux in cultured astrocytes

artículo científico publicado en 2011

Copper accumulation by cultured astrocytes.

artículo científico publicado en 2009

Copper export from cultured astrocytes.

artículo científico publicado en 2011

Copper metabolism of astrocytes.

artículo científico publicado en 2015

Copper oxide nanoparticles stimulate glycolytic flux and increase the cellular contents of glutathione and metallothioneins in cultured astrocytes.

artículo científico publicado en 2014

Copper: effects of deficiency and overload.

artículo científico publicado en 2013

Detoxification of exogenous hydrogen peroxide and organic hydroperoxides by cultured astroglial cells assessed by microtiter plate assay.

artículo científico publicado en 1998

Dicoumarol Inhibits Multidrug Resistance Protein 1-Mediated Export Processes in Cultured Primary Rat Astrocytes

scientific article published on 15 November 2018

Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes.

artículo científico publicado en 2009

Dual fluorophore doped silica nanoparticles for cellular localization studies in multiple stained cells.

artículo científico publicado en 2014

Effects of Long-Term Rice Bran Extract Supplementation on Survival, Cognition and Brain Mitochondrial Function in Aged NMRI Mice.

artículo científico publicado en 2016

Effects of iron chelators, iron salts, and iron oxide nanoparticles on the proliferation and the iron content of oligodendroglial OLN-93 cells.

artículo científico publicado en 2010

Endocytotic uptake of iron oxide nanoparticles by cultured brain microglial cells.

artículo científico publicado en 2013

Endogenous glutathione and catalase protect cultured rat astrocytes from the iron-mediated toxicity of hydrogen peroxide.

artículo científico publicado en 2004

Enhancing Cellular Uptake and Doxorubicin Delivery of Mesoporous Silica Nanoparticles via Surface Functionalization: Effects of Serum.

artículo científico publicado en 2015

Exposure of Cultured Astrocytes to Menadione Triggers Rapid Radical Formation, Glutathione Oxidation and Mrp1-Mediated Export of Glutathione Disulfide

scientific article published on 26 February 2019

Expression of hepatoma-derived growth factor family members in the adult central nervous system.

artículo científico publicado en 2006

Expression of mRNAs of multidrug resistance proteins (Mrps) in cultured rat astrocytes, oligodendrocytes, microglial cells and neurones.

artículo científico publicado en 2002

Expression of multidrug resistance proteins (Mrps) in astrocytes of the mouse brain: a single cell RT-PCR study.

artículo científico publicado en 2005

Ferritin up-regulation and transient ROS production in cultured brain astrocytes after loading with iron oxide nanoparticles.

artículo científico publicado en 2012

Formaldehyde in brain: an overlooked player in neurodegeneration?

artículo científico publicado en 2013

Formaldehyde induces rapid glutathione export from viable oligodendroglial OLN-93 cells

artículo científico publicado el 24 de septiembre de 2012

Formaldehyde metabolism and formaldehyde-induced stimulation of lactate production and glutathione export in cultured neurons.

artículo científico publicado en 2013

Formaldehyde stimulates Mrp1-mediated glutathione deprivation of cultured astrocytes

artículo científico publicado en 2011

Formate generated by cellular oxidation of formaldehyde accelerates the glycolytic flux in cultured astrocytes.

artículo científico publicado en 2012

Formation and rapid export of the monochlorobimane-glutathione conjugate in cultured rat astrocytes

artículo científico publicado en 2006

Fumaric acid diesters deprive cultured primary astrocytes rapidly of glutathione.

artículo científico publicado en 2010

Glucose-6-phosphate dehydrogenase and NADPH-consuming enzymes in the rat olfactory bulb.

artículo científico publicado en 2005

Glutamate induces release of glutathione from cultured rat astrocytes--a possible neuroprotective mechanism?

artículo científico publicado en 2008

Glutathione metabolism and oxidative stress in neurodegeneration

artículo científico publicado en 2000

Glutathione pathways in the brain.

artículo científico publicado en 2003

Glutathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes.

artículo científico publicado en 2006

Glutathione restoration as indicator for cellular metabolism of astroglial cells

artículo científico publicado en 1998

Glutathione-Dependent Detoxification Processes in Astrocytes

artículo científico publicado en 2014

Glycogen is mobilized during the disposal of peroxides by cultured astroglial cells from rat brain

scientific article published on 01 September 2000

Handling of Copper and Copper Oxide Nanoparticles by Astrocytes.

artículo científico

Handling of Iron Oxide and Silver Nanoparticles by Astrocytes

artículo científico publicado el 6 de diciembre de 2012

Hemin toxicity: a preventable source of brain damage following hemorrhagic stroke.

artículo científico publicado en 2009

How to Study the Uptake and Toxicity of Nanoparticles in Cultured Brain Cells: The Dos and Don't Forgets

artículo científico publicado en 2018

Identification of Nepsilon-(carboxymethyl)lysine-positive cells in astroglia-rich primary cultures.

artículo científico publicado en 2003

Inactivation of astrocytic glutamine synthetase by hydrogen peroxide requires iron.

artículo científico publicado en 2010

Inhibition of Astrocytic Glutamine Synthetase by Lead is Associated with a Slowed Clearance of Hydrogen Peroxide by the Glutathione System.

artículo científico publicado en 2015

Intrinsically green iron oxide nanoparticles? From synthesis via (eco-)toxicology to scenario modelling

artículo científico publicado el 19 de diciembre de 2012

Involvement of glutathione peroxidase and catalase in the disposal of exogenous hydrogen peroxide by cultured astroglial cells

artículo científico publicado el 6 de junio de 1997

Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate.

artículo científico publicado en 2004

Iron-Doping of Copper Oxide Nanoparticles Lowers Their Toxic Potential on C6 Glioma Cells

artículo científico publicado en 2020

Lysosomal iron liberation is responsible for the vulnerability of brain microglial cells to iron oxide nanoparticles: comparison with neurons and astrocytes.

artículo científico publicado en 2015

Magnetic field-induced acceleration of the accumulation of magnetic iron oxide nanoparticles by cultured brain astrocytes

artículo científico publicado en 2011

Menadione-mediated WST1 reduction assay for the determination of metabolic activity of cultured neural cells

artículo científico publicado en 2017

Metabolic and physiological responses in tissues of the long-lived bivalve Arctica islandica to oxygen deficiency

artículo científico publicado el 22 de diciembre de 2010

Metabolic pathways for glucose in astrocytes.

artículo científico publicado en 1997

Metabolism and functions of copper in brain.

artículo científico

Metabolism and functions of glutathione in brain.

artículo científico publicado en 2000

Metabolism of Cysteine in Astroglial Cells: Synthesis of Hypotaurine and Taurine

artículo científico publicado el 1 de agosto de 1998

Metabolism of Mannose in Cultured Primary Rat Neurons

artículo científico publicado en 2017

Metabolism of glycine in primary astroglial cells: synthesis of creatine, serine, and glutathione.

artículo científico publicado en 1998

Metformin Accelerates Glycolytic Lactate Production in Cultured Primary Cerebellar Granule Neurons

artículo científico publicado en 2017

Microglial cells in culture express a prominent glutathione system for the defense against reactive oxygen species.

artículo científico publicado en 2000

Modulation of Silica Nanoparticle Uptake into Human Osteoblast Cells by Variation of the Ratio of Amino and Sulfonate Surface Groups: Effects of Serum.

artículo científico publicado en 2015

Modulation of copper accumulation and copper-induced toxicity by antioxidants and copper chelators in cultured primary brain astrocytes

artículo científico publicado en 2015

Monitoring of the Cytoskeleton-Dependent Intracellular Trafficking of Fluorescent Iron Oxide Nanoparticles by Nanoparticle Pulse-Chase Experiments in C6 Glioma Cells

scientific article published on 08 September 2018

Multiassay analysis of the toxic potential of hydrogen peroxide on cultured neurons.

artículo científico publicado en 2014

Multidrug resistance protein 1-mediated export of glutathione and glutathione disulfide from brain astrocytes.

artículo científico publicado en 2005

Neurones express glutamine synthetase when deprived of glutamine or interaction with astrocytes.

artículo científico publicado en 2010

Neurotoxicity of Copper.

artículo científico publicado en 2017

Oligodendroglial cells in culture effectively dispose of exogenous hydrogen peroxide: comparison with cultured neurones, astroglial and microglial cells.

artículo científico publicado en 2002

Oxidative and antioxidative potential of brain microglial cells.

artículo científico publicado en 2005

PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments

artículo científico publicado en 2014

Pathways of neuron-astrocyte interactions and their possible role in neuroprotection.

artículo científico publicado en 2001

Peroxide detoxification by brain cells.

artículo científico publicado en 2005

Physisorption of enzymatically active chymotrypsin on titania colloidal particles

artículo científico publicado en 2015

Physisorption of α-chymotrypsin on SiO2 and TiO2: A comparative study via experiments and molecular dynamics simulations.

artículo científico publicado en 2016

Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway.

artículo científico publicado en 2005

Prostacyclin synthase is localized in rat, bovine and human neuronal brain cells.

artículo científico publicado en 1999

Rapid clearance of tertiary butyl hydroperoxide by cultured astroglial cells via oxidation of glutathione

artículo científico publicado en 1998

Reporter dyes demonstrate functional expression of multidrug resistance proteins in the marine flatworm Macrostomum lignano: the sponge-derived dye Ageladine A is not a substrate of these transporters

artículo científico publicado en 2013

Short time exposure to hydrogen peroxide induces sustained glutathione export from cultured neurons

artículo científico publicado en 2014

Structure-activity relationships for the impact of selected isothiazol-3-one biocides on glutathione metabolism and glutathione reductase of the human liver cell line Hep G2.

artículo científico publicado en 2008

Sustained hydrogen peroxide stress decreases lactate production by cultured astrocytes.

artículo científico publicado en 2009

Synergistic accumulation of iron and zinc by cultured astrocytes.

artículo científico publicado en 2010

TNF alpha increases activity of gamma-glutamyl transpeptidase in cultured rat astroglial cells.

artículo científico publicado en 2004

The Antidiabetic Drug Metformin Stimulates Glycolytic Lactate Production in Cultured Primary Rat Astrocytes.

artículo científico publicado en 2015

The Antiretroviral Protease Inhibitor Ritonavir Accelerates Glutathione Export from Cultured Primary Astrocytes

artículo científico publicado el 23 de enero de 2013

The Menadione-Mediated WST1 Reduction by Cultured Astrocytes Depends on NQO1 Activity and Cytosolic Glucose Metabolism

artículo científico publicado en 2020

The Peptide Transporter PepT2 Mediates the Uptake of the Glutathione Precursor CysGly in Astroglia‐Rich Primary Cultures

artículo científico publicado el 1 de julio de 1998

The Protein Tyrosine Kinase Inhibitor Tyrphostin 23 Strongly Accelerates Glycolytic Lactate Production in Cultured Primary Astrocytes.

artículo científico publicado en 2016

The antidiabetic drug metformin decreases mitochondrial respiration and tricarboxylic acid cycle activity in cultured primary rat astrocytes

artículo científico publicado en 2017

The antiretroviral protease inhibitors indinavir and nelfinavir stimulate Mrp1‐mediated GSH export from cultured brain astrocytes

artículo científico publicado el 11 de noviembre de 2011

The chemically synthesized ageladine A-derivative LysoGlow84 stains lysosomes in viable mammalian brain cells and specific structures in the marine flatworm Macrostomum lignano

artículo científico publicado en 2015

The cytosolic redox state of astrocytes: Maintenance, regulation and functional implications for metabolite trafficking.

artículo científico publicado en 2009

The detoxification of cumene hydroperoxide by the glutathione system of cultured astroglial cells hinges on hexose availability for the regeneration of NADPH

artículo científico publicado en 1999

The gamma-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture

artículo científico publicado en 1997

The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes.

artículo científico publicado en 2006

The multidrug resistance protein MRP1 mediates the release of glutathione disulfide from rat astrocytes during oxidative stress

scientific journal article

The pivotal role of astrocytes in the metabolism of iron in the brain.

artículo científico publicado en 2007

The putative heme transporter HCP1 is expressed in cultured astrocytes and contributes to the uptake of hemin.

artículo científico publicado en 2010

The regeneration of reduced glutathione in rat forebrain mitochondria identifies metabolic pathways providing the NADPH required

scientific article published on 01 November 1999

The tricarboxylic acid cycle activity in cultured primary astrocytes is strongly accelerated by the protein tyrosine kinase inhibitor tyrphostin 23.

artículo científico publicado en 2016

Treatment with iron oxide nanoparticles induces ferritin synthesis but not oxidative stress in oligodendroglial cells.

artículo científico publicado en 2011

Uptake and Toxicity of Copper Oxide Nanoparticles in C6 Glioma Cells.

artículo científico publicado en 2016

Uptake and metabolism of iron and iron oxide nanoparticles in brain astrocytes.

artículo científico

Uptake and metabolism of iron oxide nanoparticles in brain cells.

artículo científico publicado en 2014

Uptake and toxicity of arsenite and arsenate in cultured brain astrocytes.

artículo científico publicado en 2014

Uptake and toxicity of copper oxide nanoparticles in cultured primary brain astrocytes

artículo científico publicado en 2013

Uptake of Intact Copper Oxide Nanoparticles Causes Acute Toxicity in Cultured Glial Cells

artículo científico publicado en 2019

Uptake of dimercaptosuccinate-coated magnetic iron oxide nanoparticles by cultured brain astrocytes

artículo científico publicado en 2011

Uptake of ferrous iron by cultured rat astrocytes.

artículo científico publicado en 2010

Uptake of fluorescent iron oxide nanoparticles by oligodendroglial OLN-93 cells.

artículo científico publicado en 2013

Uptake, Metabolic Effects and Toxicity of Arsenate and Arsenite in Astrocytes.

artículo científico

Uptake, metabolism and toxicity of iron oxide nanoparticles in cultured microglia, astrocytes and neurons

artículo científico publicado en 2015

Use of Dipeptides for the Synthesis of Glutathione by Astroglia‐Rich Primary Cultures

artículo científico publicado el 1 de agosto de 1997

Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: Preference for cystine

artículo científico publicado el 1 de enero de 1998

Utilizing the protein corona around silica nanoparticles for dual drug loading and release

artículo científico publicado en 2015

Zinc prevents the copper-induced damage of cultured astrocytes.

artículo científico publicado en 2010

Zinc stimulates the production of toxic reactive oxygen species (ROS) and inhibits glutathione reductase in astrocytes.

artículo científico publicado en 2007

β-Lapachone Induces Acute Oxidative Stress in Rat Primary Astrocyte Cultures that is Terminated by the NQO1-Inhibitor Dicoumarol

scientific article published on 13 August 2020