Lista de obras - I Krimm - Dominio Público Uruguay

1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

artículo científico publicado en 2019

1H, 13C and 15N backbone resonance assignments of the dimeric yeast peroxiredoxin YLR109w.

artículo científico publicado en 2004

1H, 13C and 15N resonance assignments of the C-terminal domain of human lamin A/C

artículo científico publicado en 2002

2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site

scientific article published on 18 February 2019

A coil-helix instead of a helix-coil motif can be induced in a chloroplast transit peptide from Chlamydomonas reinhardtii

artículo científico publicado en 1999

Binding evaluation of fragment-based scaffolds for probing allosteric enzymes.

artículo científico publicado en 2012

Biochemical characterization and nuclear magnetic resonance structure of novel alpha-conotoxins isolated from the venom of Conus consors

artículo científico publicado en 1999

Crystal structure and solution NMR dynamics of a D (type II) peroxiredoxin glutaredoxin and thioredoxin dependent: a new insight into the peroxiredoxin oligomerism.

artículo científico publicado en 2005

Discovery of fragment molecules that bind the human peroxiredoxin 5 active site

artículo científico publicado en 2010

Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors

scientific article published on 04 November 2019

Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor.

artículo científico publicado en 2018

F-ara-AMP is a substrate of cytoplasmic 5'-nucleotidase II (cN-II): HPLC and NMR studies of enzymatic dephosphorylation

artículo científico publicado en 2006

Fragment-based deconstruction of Bcl-xL inhibitors

artículo científico publicado en 2010

Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities

artículo científico publicado en 2016

Glutathionylation Induces the Dissociation of 1-Cys D-peroxiredoxin Non-covalent Homodimer

artículo científico publicado en 2006

Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach

artículo científico publicado en 2015

Identifying Protein Allosteric Transitions for Drug Discovery with 1D NMR.

artículo científico publicado en 2017

Letter to the Editor:1H,13C and15N resonance assignments of poplar phloem glutaredoxin

artículo científico publicado en 2004

Ligand Specificity in Fragment-Based Drug Design

artículo científico publicado en 2010

Ligand specificity, privileged substructures and protein druggability from fragment-based screening.

artículo científico publicado en 2011

Ligand-Orientation Based Fragment Selection in STD NMR Screening

artículo científico publicado en 2015

Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin

scientific article published on 08 May 2019

NMR investigation of protein-ligand interactions for G-protein coupled receptors

scientific article published on 09 July 2019

NMR screening applied to the fragment-based generation of inhibitors of creatine kinase exploiting a new interaction proximate to the ATP binding site.

artículo científico publicado en 2007

NMR structures and activity of a novel alpha-like toxin from the scorpion Leiurus quinquestriatus hebraeus

artículo científico publicado en 1999

NMR-based analysis of protein–ligand interactions ⬇️

artículo científico publicado el 18 de abril de 2013

Overview of Probing Protein-Ligand Interactions Using NMR.

artículo científico publicado en 2015

Performance of protein-ligand docking with simulated chemical shift perturbations

artículo científico publicado en 2014

Protein-ligand structure guided by backbone and side-chain proton chemical shift perturbations

artículo científico publicado en 2014

Protein-protein interactions within peroxiredoxin systems.

artículo científico publicado en 2006

The carboxyl-terminal region common to lamins A and C contains a DNA binding domain.

artículo científico publicado en 2003

The single mutation Trp35-->Ala in the 35-40 redox site of Chlamydomonas reinhardtii thioredoxin h affects its biochemical activity and the pH dependence of C36-C39 1H-13C NMR.

artículo científico publicado en 1998

[Fragment-based screening: a promising avenue for drug design]

artículo científico publicado en 2015

Lista de obras de I Krimm

1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

1H, 13C and 15N backbone resonance assignments of the dimeric yeast peroxiredoxin YLR109w.

1H, 13C and 15N resonance assignments of the C-terminal domain of human lamin A/C

2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site

A coil-helix instead of a helix-coil motif can be induced in a chloroplast transit peptide from Chlamydomonas reinhardtii

Binding evaluation of fragment-based scaffolds for probing allosteric enzymes.

Biochemical characterization and nuclear magnetic resonance structure of novel alpha-conotoxins isolated from the venom of Conus consors

Crystal structure and solution NMR dynamics of a D (type II) peroxiredoxin glutaredoxin and thioredoxin dependent: a new insight into the peroxiredoxin oligomerism.

Discovery of fragment molecules that bind the human peroxiredoxin 5 active site

Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors

Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor.

F-ara-AMP is a substrate of cytoplasmic 5'-nucleotidase II (cN-II): HPLC and NMR studies of enzymatic dephosphorylation

Fragment-based deconstruction of Bcl-xL inhibitors

Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities

Glutathionylation Induces the Dissociation of 1-Cys D-peroxiredoxin Non-covalent Homodimer

Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach

Identifying Protein Allosteric Transitions for Drug Discovery with 1D NMR.

Letter to the Editor:1H,13C and15N resonance assignments of poplar phloem glutaredoxin

Ligand Specificity in Fragment-Based Drug Design

Ligand specificity, privileged substructures and protein druggability from fragment-based screening.

Ligand-Orientation Based Fragment Selection in STD NMR Screening

Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin

NMR investigation of protein-ligand interactions for G-protein coupled receptors

NMR screening applied to the fragment-based generation of inhibitors of creatine kinase exploiting a new interaction proximate to the ATP binding site.

NMR structures and activity of a novel alpha-like toxin from the scorpion Leiurus quinquestriatus hebraeus

NMR-based analysis of protein–ligand interactions ⬇️

Overview of Probing Protein-Ligand Interactions Using NMR.

Performance of protein-ligand docking with simulated chemical shift perturbations

Protein-ligand structure guided by backbone and side-chain proton chemical shift perturbations

Protein-protein interactions within peroxiredoxin systems.

The carboxyl-terminal region common to lamins A and C contains a DNA binding domain.

The single mutation Trp35-->Ala in the 35-40 redox site of Chlamydomonas reinhardtii thioredoxin h affects its biochemical activity and the pH dependence of C36-C39 1H-13C NMR.

[Fragment-based screening: a promising avenue for drug design]