Lista de obras -

5-HTR and 5-HTR but not 5-HTR antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood

artículo científico publicado en 2018

6 Hz corneal kindling in mice triggers neurobehavioral comorbidities accompanied by relevant changes in c-Fos immunoreactivity throughout the brain.

artículo científico publicado en 2017

A companion to the preclinical common data elements for pharmacologic studies in animal models of seizures and epilepsy. A Report of the TASK3 Pharmacology Working Group of the ILAE/AES Joint Translational Task Force

scientific article published on 15 September 2018

AT1 Receptor Mediated Hypertensive Response to Ang II in the Nucleus Tractus Solitarii of Normotensive Rats Involves NO Dependent Local GABA Release

scientific article published on 03 May 2019

Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision.

artículo científico publicado en 2015

Accelerated high-frequency repetitive transcranial magnetic stimulation enhances motor activity in rats.

artículo científico

Alterations in the motor cortical and striatal glutamatergic system and D-serine levels in the bilateral 6-hydroxydopamine rat model for Parkinson's disease.

artículo científico publicado en 2015

Altered vesicular glutamate transporter expression in human temporal lobe epilepsy with hippocampal sclerosis

artículo científico publicado en 2015

An improved microbore UHPLC method with electrochemical detection for the simultaneous determination of low monoamine levels in in vivo brain microdialysis samples

artículo científico publicado en 2016

An ultrasensitive nano UHPLC–ESI–MS/MS method for the quantification of three neuromedin-like peptides in microdialysates

artículo científico publicado en 2015

Ang II and Ang IV: unraveling the mechanism of action on synaptic plasticity, memory, and epilepsy

artículo científico publicado en 2008

Anticonvulsant and antiepileptogenic effects of system xc- inactivation in chronic epilepsy models

artículo científico publicado en 2019

Anticonvulsant effect of a ghrelin receptor agonist in 6Hz corneally kindled mice

artículo científico publicado en 2016

Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?

artículo científico publicado en 2013

Assessing mixtures of supercharging agents to increase the abundance of a specific charge state of Neuromedin U

artículo científico publicado en 2019

Astrocytic Connexin43 Channels as Candidate Targets in Epilepsy Treatment

scientific article published on 20 November 2020

Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory

scientific article published on 17 May 2018

Blood-brain barrier transport kinetics of the neuromedin peptides NMU, NMN, NMB and NT.

artículo científico publicado en 2016

Brain and peripheral angiotensin II type 1 receptors mediate renal vasoconstrictor and blood pressure responses to angiotensin IV in the rat.

artículo científico publicado en 2008

Caloric Restriction Protects against Lactacystin-Induced Degeneration of Dopamine Neurons Independent of the Ghrelin Receptor.

artículo científico publicado en 2017

Cellular targets for angiotensin II fragments: pharmacological and molecular evidence.

artículo científico publicado en 2002

Cerebral Cortical Circuitry Formation Requires Functional Glycine Receptors

artículo científico publicado en 2016

Challenges for the in vivo quantification of brain neuropeptides using microdialysis sampling and LC-MS.

artículo científico publicado en 2016

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3

artículo científico publicado en 2018

Combination of group I mGlu receptors antagonist with dopaminergic agonists strengthens the synaptic transmission at corticostriatal synapses in culture.

artículo científico publicado en 2012

Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed

artículo científico publicado en 2015

Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish.

artículo científico publicado en 2015

Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures ⬇️

artículo científico publicado el 25 de mayo de 2011

Des-acyl ghrelin attenuates pilocarpine-induced limbic seizures via the ghrelin receptor and not the orexin pathway

artículo científico publicado en 2015

Development of potent and proteolytically stable human neuromedin U receptor agonists.

artículo científico publicado en 2017

Disruption of the HPA-axis through corticosterone-release pellets induces robust depressive-like behavior and reduced BDNF levels in mice

artículo científico publicado en 2016

Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.

artículo científico publicado en 2010

Effects of AT1 receptor antagonism on kainate-induced seizures and concomitant changes in hippocampal extracellular noradrenaline, serotonin, and dopamine levels in Wistar-Kyoto and spontaneously hypertensive rats

artículo científico publicado en 2015

Effects of disrupted ghrelin receptor function on fear processing, anxiety and saccharin preference in mice

artículo científico publicado en 2019

Effects of neuromedin U-8 on stress responsiveness and hypothalamus-pituitary-adrenal axis activity in male C57BL/6J mice

artículo científico publicado en 2020

Erratum to "Selective Changes in Locomotor Activity in Mice Due to Low-intensity Microwaves Amplitude Modulated in the EEG Spectral Domain" [Neuroscience 359 (2017) 40-48]

artículo científico publicado en 2018

GABAergic Signaling Mediates Central Cardiovascular Angiotensin II Type 2 Receptor Effects.

artículo científico publicado en 2018

Genetic and pharmacological manipulation of glial glutamate transporters does not alter infection-induced seizure activity

scientific article published on 22 April 2019

Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice.

artículo científico publicado en 2018

Ghrelin: an emerging new anticonvulsant neuropeptide.

artículo científico

High-affinity Na+/K+-dependent glutamate transporter EAAT4 is expressed throughout the rat fore- and midbrain.

artículo científico publicado en 2008

Higher-Density Culture in Human Embryonic Stem Cells Results in DNA Damage and Genome Instability.

artículo científico publicado en 2016

Hypotensive Response to Angiotensin II Type 2 Receptor Stimulation in the Rostral Ventrolateral Medulla Requires Functional GABA-A Receptors

artículo científico publicado en 2017

Hypotensive and sympathoinhibitory responses to selective central AT2 receptor stimulation in spontaneously hypertensive rats

artículo científico publicado en 2015

IRAP and AT(1) receptor mediated effects of angiotensin IV.

artículo científico publicado en 2009

Identification of GSK-3 as a potential therapeutic entry point for epilepsy

article

Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.

artículo científico publicado en 2014

In-depth behavioral characterization of the corticosterone mouse model and the critical involvement of housing conditions.

artículo científico publicado en 2015

In-vitro and in-vivo evaluation of the modulatory effects of the multitarget compound ASS234 on the monoaminergic system.

artículo científico publicado en 2017

Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory

artículo científico publicado en 2016

Inhibition of astroglial connexin43 hemichannels with TAT-Gap19 exerts anticonvulsant effects in rodents.

artículo científico publicado en 2018

LC-method development for the quantification of neuromedin-like peptides. Emphasis on column choice and mobile phase composition

artículo científico publicado en 2017

Monoaminergic Mechanisms in Epilepsy May Offer Innovative Therapeutic Opportunity for Monoaminergic Multi-Target Drugs

artículo científico publicado en 2016

Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases

artículo científico publicado en 2016

Neuromedin U and Structural Analogs: an Overview of Their Structure, Function and Selectivity

artículo científico publicado en 2019

Neuropeptide FF receptors as novel targets for limbic seizure attenuation

artículo científico publicado en 2015

Neuropeptide Y increases in vivo hippocampal extracellular glutamate levels through Y1 receptor activation.

artículo científico publicado en 2012

Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein

artículo científico publicado en 2015

Pharmacological Analysis of the Anti-epileptic Mechanisms of Fenfluramine in scn1a Mutant Zebrafish.

artículo científico publicado en 2017

Reassessment of the antioxidative mixture for the challenging electrochemical determination of dopamine, noradrenaline and serotonin in microdialysis samples.

artículo científico publicado en 2015

Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated.

artículo científico publicado en 2010

Running Opposes the Effects of Social Isolation on Synaptic Plasticity and Transmission in a Rat Model of Depression.

artículo científico publicado en 2016

Selective changes in locomotor activity in mice due to low-intensity microwaves amplitude modulated in the EEG spectral domain.

artículo científico publicado en 2017

Sensitive targeted methods for brain metabolomic studies in microdialysis samples

artículo científico publicado en 2018

Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model

artículo científico publicado en 2016

Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1

article by Yana Van Den Herrewegen et al published 20 September 2021 in Molecular Brain

Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model

artículo científico publicado en 2017

Synthesis and in Vitro Evaluation of Stabilized and Selective Neuromedin U-1 Receptor Agonists

scientific article published on 23 April 2018

The Barnes Maze Task Reveals Specific Impairment of Spatial Learning Strategy in the Intrahippocampal Kainic Acid Model for Temporal Lobe Epilepsy

artículo científico publicado en 2018

The effect of neuropeptide FF in the amygdala kindling model.

artículo científico publicado en 2015

Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures.

artículo científico publicado en 2015

Validation of the 6 Hz refractory seizure mouse model for intracerebroventricularly administered compounds.

artículo científico publicado en 2015

Zonisamide attenuates lactacystin-induced parkinsonism in mice without affecting system xc.

artículo científico publicado en 2016

Lista de obras de

5-HTR and 5-HTR but not 5-HTR antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood

6 Hz corneal kindling in mice triggers neurobehavioral comorbidities accompanied by relevant changes in c-Fos immunoreactivity throughout the brain.

A companion to the preclinical common data elements for pharmacologic studies in animal models of seizures and epilepsy. A Report of the TASK3 Pharmacology Working Group of the ILAE/AES Joint Translational Task Force

AT1 Receptor Mediated Hypertensive Response to Ang II in the Nucleus Tractus Solitarii of Normotensive Rats Involves NO Dependent Local GABA Release

Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision.

Accelerated high-frequency repetitive transcranial magnetic stimulation enhances motor activity in rats.

Alterations in the motor cortical and striatal glutamatergic system and D-serine levels in the bilateral 6-hydroxydopamine rat model for Parkinson's disease.

Altered vesicular glutamate transporter expression in human temporal lobe epilepsy with hippocampal sclerosis

An improved microbore UHPLC method with electrochemical detection for the simultaneous determination of low monoamine levels in in vivo brain microdialysis samples

An ultrasensitive nano UHPLC–ESI–MS/MS method for the quantification of three neuromedin-like peptides in microdialysates

Ang II and Ang IV: unraveling the mechanism of action on synaptic plasticity, memory, and epilepsy

Anticonvulsant and antiepileptogenic effects of system xc- inactivation in chronic epilepsy models

Anticonvulsant effect of a ghrelin receptor agonist in 6Hz corneally kindled mice

Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?

Assessing mixtures of supercharging agents to increase the abundance of a specific charge state of Neuromedin U

Astrocytic Connexin43 Channels as Candidate Targets in Epilepsy Treatment

Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory

Blood-brain barrier transport kinetics of the neuromedin peptides NMU, NMN, NMB and NT.

Brain and peripheral angiotensin II type 1 receptors mediate renal vasoconstrictor and blood pressure responses to angiotensin IV in the rat.

Caloric Restriction Protects against Lactacystin-Induced Degeneration of Dopamine Neurons Independent of the Ghrelin Receptor.

Cellular targets for angiotensin II fragments: pharmacological and molecular evidence.

Cerebral Cortical Circuitry Formation Requires Functional Glycine Receptors

Challenges for the in vivo quantification of brain neuropeptides using microdialysis sampling and LC-MS.

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3

Combination of group I mGlu receptors antagonist with dopaminergic agonists strengthens the synaptic transmission at corticostriatal synapses in culture.

Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed

Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish.

Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures ⬇️

Des-acyl ghrelin attenuates pilocarpine-induced limbic seizures via the ghrelin receptor and not the orexin pathway

Development of potent and proteolytically stable human neuromedin U receptor agonists.

Disruption of the HPA-axis through corticosterone-release pellets induces robust depressive-like behavior and reduced BDNF levels in mice

Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.

Effects of AT1 receptor antagonism on kainate-induced seizures and concomitant changes in hippocampal extracellular noradrenaline, serotonin, and dopamine levels in Wistar-Kyoto and spontaneously hypertensive rats

Effects of disrupted ghrelin receptor function on fear processing, anxiety and saccharin preference in mice

Effects of neuromedin U-8 on stress responsiveness and hypothalamus-pituitary-adrenal axis activity in male C57BL/6J mice

Erratum to "Selective Changes in Locomotor Activity in Mice Due to Low-intensity Microwaves Amplitude Modulated in the EEG Spectral Domain" [Neuroscience 359 (2017) 40-48]

GABAergic Signaling Mediates Central Cardiovascular Angiotensin II Type 2 Receptor Effects.

Genetic and pharmacological manipulation of glial glutamate transporters does not alter infection-induced seizure activity

Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice.

Ghrelin: an emerging new anticonvulsant neuropeptide.

High-affinity Na+/K+-dependent glutamate transporter EAAT4 is expressed throughout the rat fore- and midbrain.

Higher-Density Culture in Human Embryonic Stem Cells Results in DNA Damage and Genome Instability.

Hypotensive Response to Angiotensin II Type 2 Receptor Stimulation in the Rostral Ventrolateral Medulla Requires Functional GABA-A Receptors

Hypotensive and sympathoinhibitory responses to selective central AT2 receptor stimulation in spontaneously hypertensive rats

IRAP and AT(1) receptor mediated effects of angiotensin IV.

Identification of GSK-3 as a potential therapeutic entry point for epilepsy

Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.

In-depth behavioral characterization of the corticosterone mouse model and the critical involvement of housing conditions.

In-vitro and in-vivo evaluation of the modulatory effects of the multitarget compound ASS234 on the monoaminergic system.

Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory

Inhibition of astroglial connexin43 hemichannels with TAT-Gap19 exerts anticonvulsant effects in rodents.

LC-method development for the quantification of neuromedin-like peptides. Emphasis on column choice and mobile phase composition

Monoaminergic Mechanisms in Epilepsy May Offer Innovative Therapeutic Opportunity for Monoaminergic Multi-Target Drugs

Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases

Neuromedin U and Structural Analogs: an Overview of Their Structure, Function and Selectivity

Neuropeptide FF receptors as novel targets for limbic seizure attenuation

Neuropeptide Y increases in vivo hippocampal extracellular glutamate levels through Y1 receptor activation.

Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein

Pharmacological Analysis of the Anti-epileptic Mechanisms of Fenfluramine in scn1a Mutant Zebrafish.

Reassessment of the antioxidative mixture for the challenging electrochemical determination of dopamine, noradrenaline and serotonin in microdialysis samples.

Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated.

Running Opposes the Effects of Social Isolation on Synaptic Plasticity and Transmission in a Rat Model of Depression.

Selective changes in locomotor activity in mice due to low-intensity microwaves amplitude modulated in the EEG spectral domain.

Sensitive targeted methods for brain metabolomic studies in microdialysis samples

Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model

Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1

Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model

Synthesis and in Vitro Evaluation of Stabilized and Selective Neuromedin U-1 Receptor Agonists

The Barnes Maze Task Reveals Specific Impairment of Spatial Learning Strategy in the Intrahippocampal Kainic Acid Model for Temporal Lobe Epilepsy

The effect of neuropeptide FF in the amygdala kindling model.

Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures.

Validation of the 6 Hz refractory seizure mouse model for intracerebroventricularly administered compounds.

Zonisamide attenuates lactacystin-induced parkinsonism in mice without affecting system xc.