Lista de obras -

A novel sialyltransferase inhibitor AL10 suppresses invasion and metastasis of lung cancer cells by inhibiting integrin-mediated signaling.

artículo científico publicado en 2010

A novel sialyltransferase inhibitor suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways

artículo científico publicado en 2011

A synthetic podophyllotoxin derivative exerts anti-cancer effects by inducing mitotic arrest and pro-apoptotic ER stress in lung cancer preclinical models

artículo científico publicado en 2013

Aggregation induced emission enhancement (AIEE) characteristics of quinoline based compound - A versatile fluorescent probe for pH, Fe(III) ion, BSA binding and optical cell imaging.

artículo científico publicado en 2017

Aggregation-induced emission enhancement of anthracene-derived Schiff base compounds and their application as a sensor for bovine serum albumin and optical cell imaging

artículo científico publicado en 2018

Aminopeptidase p mediated detoxification of organophosphonate analogues of sarin: mechanistic and stereochemical study at the phosphorus atom of the substrate

artículo científico publicado en 2006

Antiangiogenic Effect of Isomalyngamide A Riboside CY01 in Breast Cancer Cells via Inhibition of Migration, Tube Formation and pVEGFR2/pAKT Signals

scientific article published on 19 October 2019

Anticancer efficacy of unique pyridine-based tetraindoles

artículo científico publicado en 2015

Benzenesulfonamide Derivatives as Calcium/Calmodulin-Dependent Protein Kinase Inhibitors and Antiviral Agents against Dengue and Zika Virus Infections

scientific article published on 03 February 2020

Design of potent inhibitors for Schistosoma japonica glutathione S-transferase

artículo científico publicado en 2005

Elevation of β-galactoside α2,6-sialyltransferase 1 in a fructoseresponsive manner promotes pancreatic cancer metastasis.

scientific article published on 09 December 2016

Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site

artículo científico publicado en 2003

Enzymatic and nonenzymatic synthesis of glutathione conjugates: application to the understanding of a parasite's defense system and alternative to the discovery of potent glutathione S-transferase inhibitors

artículo científico publicado en 2007

Enzymatic synthesis of chiral organophosphothioates from prochiral precursors

artículo científico publicado en 2002

Evaluation of organophosphorus chemicals-degrading enzymes: a comparison of Escherichia coli and human cytosolic aminopeptidase P.

artículo científico publicado en 2008

Experimental verification of a predicted, previously unseen separation selectivity pattern in the capillary electrophoretic separation of noncharged enantiomers by octakis(2,3-diacetyl-6-sulfato)-gamma-cyclodextrin

artículo científico publicado en 2000

Glycosylation enhances the anti-migratory activities of isomalyngamide A analogs

artículo científico publicado en 2013

Inhibition of chemokine (C-C motif) receptor 7 sialylation suppresses CCL19-stimulated proliferation, invasion and anti-anoikis

artículo científico publicado en 2014

Inhibition of glutathione S-transferase M1 by new gabosine analogues is essential for overcoming cisplatin resistance in lung cancer cells.

artículo científico publicado en 2011

Investigation of the proton relay system operative in human cystosolic aminopeptidase P.

artículo científico publicado en 2018

Isomalyngamide A, A-1 and their analogs suppress cancer cell migration in vitro

artículo científico publicado en 2011

Liposomal Irinotecan for Treatment of Colorectal Cancer in a Preclinical Model

Liposomal paclitaxel induces fewer hematopoietic and cardiovascular complications than bioequivalent doses of Taxol

artículo científico publicado en 2018

Lithocholic acid analogues, new and potent alpha-2,3-sialyltransferase inhibitors.

artículo científico publicado en 2006

Long-range through-bond photoactivated sigma bond cleavage in steroids. Intramolecular sensitized debromination

scientific article published on 01 January 2000

Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers

artículo científico publicado en 2018

Nature-inspired design of tetraindoles: Optimization of the core structure and evaluation of structure-activity relationship

artículo científico publicado en 2016

Overcoming the drug resistance in breast cancer cells by rational design of efficient glutathione S-transferase inhibitors.

artículo científico publicado en 2010

Oxidations of N-(3-indoleethyl) cyclic aliphatic amines by horseradish peroxidase: the indole ring binds to the enzyme and mediates electron-transfer amine oxidation.

artículo científico publicado en 2007

Oxidative trimerization of indoles via water-assisted visible-light photoredox catalysis and the study of their anti-cancer activities

scientific article published on 31 July 2020

Polyfluorinated bipyridine cisplatins manipulate cytotoxicity through the induction of S-G2/M arrest and partial intercalation mechanism

scientific article published on 28 June 2011

Preparation and characterization of amino-linked heterocyclic carbene palladium, gold, and silver complexes and their use as anticancer agents that act by triggering apoptotic cell death.

artículo científico publicado en 2011

Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis

artículo científico publicado en 2020

Stereoselective detoxification of chiral sarin and soman analogues by phosphotriesterase.

artículo científico publicado en 2001

Synthesis and evaluation of the cytotoxicities of tetraindoles: observation that the 5-hydroxy tetraindole (SK228) induces G₂ arrest and apoptosis in human breast cancer cells.

artículo científico publicado en 2012

Synthesis and structure-activity relationships of novel furazan-3,4-diamide analogs as potent anti-cancer agents

artículo científico publicado en 2009

Synthesis of B- and C-ring-modified lithocholic acid analogues as potential sialyltransferase inhibitors

artículo científico publicado en 2016

Tetrac downregulates β-catenin and HMGA2 to promote the effect of resveratrol in colon cancer

artículo científico publicado en 2017

The novel indole compound SK228 induces apoptosis and FAK/Paxillin disruption in tumor cell lines and inhibits growth of tumor graft in the nude mouse.

artículo científico publicado en 2011

The tetraindole SK228 reverses the epithelial-to-mesenchymal transition of breast cancer cells by up-regulating members of the miR-200 family.

artículo científico publicado en 2014

Tyrosine 387 and arginine 404 are critical in the hydrolytic mechanism of Escherichia coli aminopeptidase P.

artículo científico publicado en 2006

Lista de obras de

A novel sialyltransferase inhibitor AL10 suppresses invasion and metastasis of lung cancer cells by inhibiting integrin-mediated signaling.

A novel sialyltransferase inhibitor suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways

A synthetic podophyllotoxin derivative exerts anti-cancer effects by inducing mitotic arrest and pro-apoptotic ER stress in lung cancer preclinical models

Aggregation induced emission enhancement (AIEE) characteristics of quinoline based compound - A versatile fluorescent probe for pH, Fe(III) ion, BSA binding and optical cell imaging.

Aggregation-induced emission enhancement of anthracene-derived Schiff base compounds and their application as a sensor for bovine serum albumin and optical cell imaging

Aminopeptidase p mediated detoxification of organophosphonate analogues of sarin: mechanistic and stereochemical study at the phosphorus atom of the substrate

Antiangiogenic Effect of Isomalyngamide A Riboside CY01 in Breast Cancer Cells via Inhibition of Migration, Tube Formation and pVEGFR2/pAKT Signals

Anticancer efficacy of unique pyridine-based tetraindoles

Benzenesulfonamide Derivatives as Calcium/Calmodulin-Dependent Protein Kinase Inhibitors and Antiviral Agents against Dengue and Zika Virus Infections

Design of potent inhibitors for Schistosoma japonica glutathione S-transferase

Elevation of β-galactoside α2,6-sialyltransferase 1 in a fructoseresponsive manner promotes pancreatic cancer metastasis.

Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site

Enzymatic and nonenzymatic synthesis of glutathione conjugates: application to the understanding of a parasite's defense system and alternative to the discovery of potent glutathione S-transferase inhibitors

Enzymatic synthesis of chiral organophosphothioates from prochiral precursors

Evaluation of organophosphorus chemicals-degrading enzymes: a comparison of Escherichia coli and human cytosolic aminopeptidase P.

Experimental verification of a predicted, previously unseen separation selectivity pattern in the capillary electrophoretic separation of noncharged enantiomers by octakis(2,3-diacetyl-6-sulfato)-gamma-cyclodextrin

Glycosylation enhances the anti-migratory activities of isomalyngamide A analogs

Inhibition of chemokine (C-C motif) receptor 7 sialylation suppresses CCL19-stimulated proliferation, invasion and anti-anoikis

Inhibition of glutathione S-transferase M1 by new gabosine analogues is essential for overcoming cisplatin resistance in lung cancer cells.

Investigation of the proton relay system operative in human cystosolic aminopeptidase P.

Isomalyngamide A, A-1 and their analogs suppress cancer cell migration in vitro

Liposomal Irinotecan for Treatment of Colorectal Cancer in a Preclinical Model

Liposomal paclitaxel induces fewer hematopoietic and cardiovascular complications than bioequivalent doses of Taxol

Lithocholic acid analogues, new and potent alpha-2,3-sialyltransferase inhibitors.

Long-range through-bond photoactivated sigma bond cleavage in steroids. Intramolecular sensitized debromination

Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers

Nature-inspired design of tetraindoles: Optimization of the core structure and evaluation of structure-activity relationship

Overcoming the drug resistance in breast cancer cells by rational design of efficient glutathione S-transferase inhibitors.

Oxidations of N-(3-indoleethyl) cyclic aliphatic amines by horseradish peroxidase: the indole ring binds to the enzyme and mediates electron-transfer amine oxidation.

Oxidative trimerization of indoles via water-assisted visible-light photoredox catalysis and the study of their anti-cancer activities

Polyfluorinated bipyridine cisplatins manipulate cytotoxicity through the induction of S-G2/M arrest and partial intercalation mechanism

Preparation and characterization of amino-linked heterocyclic carbene palladium, gold, and silver complexes and their use as anticancer agents that act by triggering apoptotic cell death.

Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis

Stereoselective detoxification of chiral sarin and soman analogues by phosphotriesterase.

Synthesis and evaluation of the cytotoxicities of tetraindoles: observation that the 5-hydroxy tetraindole (SK228) induces G₂ arrest and apoptosis in human breast cancer cells.

Synthesis and structure-activity relationships of novel furazan-3,4-diamide analogs as potent anti-cancer agents

Synthesis of B- and C-ring-modified lithocholic acid analogues as potential sialyltransferase inhibitors

Tetrac downregulates β-catenin and HMGA2 to promote the effect of resveratrol in colon cancer

The novel indole compound SK228 induces apoptosis and FAK/Paxillin disruption in tumor cell lines and inhibits growth of tumor graft in the nude mouse.

The tetraindole SK228 reverses the epithelial-to-mesenchymal transition of breast cancer cells by up-regulating members of the miR-200 family.

Tyrosine 387 and arginine 404 are critical in the hydrolytic mechanism of Escherichia coli aminopeptidase P.