Lista de obras -

11 beta-hydroxysteroid dehydrogenase type 1 is a predominant 11 beta-reductase in the intact perfused rat liver

scientific article published on 01 June 2000

11β-Hydroxysteroid dehydrogenase activity in the brain does not contribute to systemic interconversion of cortisol and cortisone in healthy men.

artículo científico publicado en 2014

11β-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7β-hydroxycholesterol ⬇️

artículo científico publicado el 23 de agosto de 2012

5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor.

artículo científico publicado en 2004

5α-Reduced glucocorticoids: a story of natural selection.

artículo científico

5α-Reductase type 1 deficiency or inhibition predisposes to insulin resistance, hepatic steatosis, and liver fibrosis in rodents

artículo científico publicado en 2014

5α-reduced glucocorticoids exhibit dissociated anti-inflammatory and metabolic effects.

artículo científico publicado en 2011

5α-reductase type 1 modulates insulin sensitivity in men.

artículo científico publicado en 2014

7-oxysterols modulate glucocorticoid activity in adipocytes through competition for 11beta-hydroxysteroid dehydrogenase type.

artículo científico publicado en 2008

A combination of polymorphisms in HSD11B1 associates with in vivo 11{beta}-HSD1 activity and metabolic syndrome in women with and without polycystic ovary syndrome

artículo científico publicado en 2011

Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance.

artículo científico publicado en 2002

Activation of the Hypothalamic-Pituitary-Adrenal Axis in Adults With Mineralocorticoid Receptor Haploinsufficiency

artículo científico publicado en 2014

Acute in vivo regulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by insulin and intralipid infusions in humans.

artículo científico publicado en 2006

Acute interaction between hydrocortisone and insulin alters the plasma metabolome in humans

artículo científico publicado en 2017

Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study.

artículo científico publicado en 2002

Analysis of biogenic amines in plasma of hypertensive patients and a control group

scientific article published on 01 November 1993

Apparent cortisone reductase deficiency: a functional defect in 11beta-hydroxysteroid dehydrogenase type 1

scientific article published on 01 October 1999

Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity.

artículo científico publicado en 2017

Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue

artículo científico publicado en 2012

Clinical measurement of steroid metabolism.

artículo científico publicado en 2001

Convergence in insulin resistance between very severely obese and lean women at the end of pregnancy.

artículo científico publicado en 2015

Cortisol metabolic predictors of response to psychotherapy for symptoms of PTSD in survivors of the World Trade Center attacks on September 11, 2001.

artículo científico publicado en 2009

Decreased maternal hypothalamic-pituitary-adrenal axis activity in very severely obese pregnancy: Associations with birthweight and gestation at delivery.

artículo científico publicado en 2015

Dehydroepiandrosterone 7-hydroxylase CYP7B: predominant expression in primate hippocampus and reduced expression in Alzheimer's disease.

artículo científico publicado en 2003

Deletion of the androgen receptor in adipose tissue in male mice elevates retinol binding protein 4 and reveals independent effects on visceral fat mass and on glucose homeostasis.

artículo científico publicado en 2012

Derivatization enhances analysis of estrogens and their bioactive metabolites in human plasma by liquid chromatography tandem mass spectrometry

artículo científico publicado en 2018

Development of a derivatisation method for the analysis of aldehyde modified amino acid residues in proteins by Fourier transform mass spectrometry.

artículo científico publicado en 2008

Development-related increase in cortisol biosynthesis by human granulosa cells

artículo científico publicado en 2000

Diet-induced weight loss has chronic tissue-specific effects on glucocorticoid metabolism in overweight postmenopausal women

artículo científico publicado en 2014

Displacement of cortisol from human heart by acute administration of a mineralocorticoid receptor antagonist

artículo científico publicado en 2013

Distinguishing the Activities of 11β-Hydroxysteroid Dehydrogenasesin VivoUsing Isotopically Labeled Cortisol ⬇️

artículo científico publicado el 1 de enero de 2002

Distribution of glucocorticoid and mineralocorticoid receptors and 11beta-hydroxysteroid dehydrogenases in human and rat ocular tissues.

artículo científico publicado en 2000

Effects of Gonadectomy on Glucocorticoid Metabolism in Obese Zucker Rats

artículo científico publicado en 2007

Effects of Peroxisome Proliferator-Activated Receptor-α and -γ Agonists on 11β-Hydroxysteroid Dehydrogenase Type 1 in Subcutaneous Adipose Tissue in Men

artículo científico publicado en 2007

Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with Type 2 diabetes with and without fatty liver

artículo científico publicado en 2014

Effects of proportions of dietary macronutrients on glucocorticoid metabolism in diet-induced obesity in rats

artículo científico publicado en 2010

Enduring effects of severe developmental adversity, including nutritional deprivation, on cortisol metabolism in aging Holocaust survivors

artículo científico publicado en 2009

Estrogens and Glucocorticoids in Mammary Adipose Tissue: Relationships with Body Mass Index and Breast Cancer Features

artículo científico publicado en 2020

Exploring the Temporal Relation between Body Mass Index and Corticosteroid Metabolite Excretion in Childhood

artículo científico publicado en 2020

Future technology insight: mass spectrometry imaging as a tool in drug research and development

artículo científico publicado en 2015

Gas chromatography tandem mass spectrometry offers advantages for urinary steroids analysis.

artículo científico publicado en 2017

Glucocorticoid metabolism within superficial subcutaneous rather than visceral adipose tissue is associated with features of the metabolic syndrome in South African women.

artículo científico publicado en 2006

Glucocorticoids are lower at delivery in maternal, but not cord blood of obese pregnancies

artículo científico publicado en 2017

Glucocorticoids turn over slowly in human adipose tissue in vivo

artículo científico publicado en 2010

Heritability of Cortisol Production and Metabolism Throughout Adolescence

scientific article published on 01 February 2020

Higher Insulin Resistance and Adiposity in Postmenopausal Women With Breast Cancer Treated With Aromatase Inhibitors

artículo científico publicado en 2019

Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study

scientific article published on 10 April 2019

Increased A-ring reduction of glucocorticoids in obese Zucker rats: effects of insulin sensitization.

artículo científico publicado en 2005

Increased glucocorticoid activity in men with cardiovascular risk factors

scientific article published on 01 April 1998

Increased glucocorticoid production and altered cortisol metabolism in women with mild to moderate Alzheimer's disease.

artículo científico publicado en 2001

Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone.

artículo científico publicado en 2005

Increased skeletal muscle 11βHSD1 mRNA is associated with lower muscle strength in ageing.

artículo científico publicado en 2013

Increased whole-body and sustained liver cortisol regeneration by 11beta-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target for enzyme inhibition ⬇️

artículo científico publicado en 2011

Influence of gender and body composition on glucocorticoid metabolism in middle-aged humans

scientific article published on 01 June 2000

Intra-adipose sex steroid metabolism and body fat distribution in idiopathic human obesity

artículo científico publicado en 2007

Is there a gender difference in the associations of birthweight and adult hypothalamic-pituitary-adrenal axis activity?

artículo científico publicado en 2005

It takes two to tango: dimerisation of glucocorticoid receptor and its anti-inflammatory functions.

artículo científico publicado en 2012

Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism.

artículo científico publicado en 2009

Long-Term Stability of Cortisol Production and Metabolism Throughout Adolescence: Longitudinal Twin Study

scientific article published on 25 March 2020

Mapping endocrine networks by stable isotope tracing

artículo científico publicado en 2022

Mass spectrometry imaging for dissecting steroid intracrinology within target tissues

artículo científico publicado en 2013

Maternal Glucocorticoid Metabolism Across Pregnancy: A Potential Mechanism Underlying Fetal Glucocorticoid Exposure

scientific article published on 01 March 2020

Measurement of tamsulosin in human serum by liquid chromatography-tandem mass spectrometry.

artículo científico publicado en 2013

Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: implications for the pathogenesis of steatohepatitis ⬇️

artículo científico publicado el 30 de noviembre de 2010

Obesity and Gender Influence Cortisol Secretion and Metabolism in Man ⬇️

artículo científico publicado el 1 de mayo de 1998

Physiological and pathophysiological applications of sensitive ELISA methods for urinary deoxycorticosterone and corticosterone in rodents.

artículo científico publicado en 2009

Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia.

artículo científico publicado en 2017

Prenatal stress reduces postnatal neurogenesis in rats selectively bred for high, but not low, anxiety: possible key role of placental 11beta-hydroxysteroid dehydrogenase type 2.

artículo científico publicado en 2008

Relative adrenal insufficiency in mice deficient in 5α-reductase 1

artículo científico publicado en 2014

Renal sodium retention in cirrhotic rats depends on glucocorticoid-mediated activation of mineralocorticoid receptor due to decreased renal 11beta-HSD-2 activity

artículo científico publicado en 2006

Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice

artículo científico publicado en 2019

Sexual dimorphism in cortisol metabolism throughout pubertal development: a longitudinal study

artículo científico publicado en 2020

Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry

artículo científico publicado en 2014

The postprandial rise in plasma cortisol in men is mediated by macronutrient-specific stimulation of adrenal and extra-adrenal cortisol production

artículo científico publicado en 2013

The role of corticosterone in human hypothalamic-pituitary-adrenal axis feedback.

artículo científico publicado en 2006

The role of glucocorticoids in sodium retention in cirrhotic patients: a double blind, randomized, crossover study

artículo científico publicado en 2012

Tissue production of cortisol by 11beta-hydroxysteroid dehydrogenase type 1 and metabolic disease.

artículo científico publicado en 2006

Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

artículo científico publicado en 2002

Tissue-specific dysregulation of 11β-hydroxysteroid dehydrogenase type 1 in overweight/obese women with polycystic ovary syndrome compared with weight-matched controls

artículo científico publicado en 2014

Tissue-specific dysregulation of cortisol regeneration by 11βHSD1 in obesity: has it promised too much?

artículo científico

Tissue-specific increases in 11beta-hydroxysteroid dehydrogenase type 1 in normal weight postmenopausal women.

artículo científico publicado en 2009

Truncal distribution of fat mass, metabolic profile and hypothalamic-pituitary adrenal axis activity in prepubertal obese children.

artículo científico publicado en 2007

Urinary estrogens as a non-invasive biomarker of viable pregnancy in the giant panda (Ailuropoda melanoleuca)

artículo científico publicado en 2019

Lista de obras de

11 beta-hydroxysteroid dehydrogenase type 1 is a predominant 11 beta-reductase in the intact perfused rat liver

11β-Hydroxysteroid dehydrogenase activity in the brain does not contribute to systemic interconversion of cortisol and cortisone in healthy men.

11β-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7β-hydroxycholesterol ⬇️

5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor.

5α-Reduced glucocorticoids: a story of natural selection.

5α-Reductase type 1 deficiency or inhibition predisposes to insulin resistance, hepatic steatosis, and liver fibrosis in rodents

5α-reduced glucocorticoids exhibit dissociated anti-inflammatory and metabolic effects.

5α-reductase type 1 modulates insulin sensitivity in men.

7-oxysterols modulate glucocorticoid activity in adipocytes through competition for 11beta-hydroxysteroid dehydrogenase type.

A combination of polymorphisms in HSD11B1 associates with in vivo 11{beta}-HSD1 activity and metabolic syndrome in women with and without polycystic ovary syndrome

Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance.

Activation of the Hypothalamic-Pituitary-Adrenal Axis in Adults With Mineralocorticoid Receptor Haploinsufficiency

Acute in vivo regulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by insulin and intralipid infusions in humans.

Acute interaction between hydrocortisone and insulin alters the plasma metabolome in humans

Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study.

Analysis of biogenic amines in plasma of hypertensive patients and a control group

Apparent cortisone reductase deficiency: a functional defect in 11beta-hydroxysteroid dehydrogenase type 1

Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity.

Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue

Clinical measurement of steroid metabolism.

Convergence in insulin resistance between very severely obese and lean women at the end of pregnancy.

Cortisol metabolic predictors of response to psychotherapy for symptoms of PTSD in survivors of the World Trade Center attacks on September 11, 2001.

Decreased maternal hypothalamic-pituitary-adrenal axis activity in very severely obese pregnancy: Associations with birthweight and gestation at delivery.

Dehydroepiandrosterone 7-hydroxylase CYP7B: predominant expression in primate hippocampus and reduced expression in Alzheimer's disease.

Deletion of the androgen receptor in adipose tissue in male mice elevates retinol binding protein 4 and reveals independent effects on visceral fat mass and on glucose homeostasis.

Derivatization enhances analysis of estrogens and their bioactive metabolites in human plasma by liquid chromatography tandem mass spectrometry

Development of a derivatisation method for the analysis of aldehyde modified amino acid residues in proteins by Fourier transform mass spectrometry.

Development-related increase in cortisol biosynthesis by human granulosa cells

Diet-induced weight loss has chronic tissue-specific effects on glucocorticoid metabolism in overweight postmenopausal women

Displacement of cortisol from human heart by acute administration of a mineralocorticoid receptor antagonist

Distinguishing the Activities of 11β-Hydroxysteroid Dehydrogenasesin VivoUsing Isotopically Labeled Cortisol ⬇️

Distribution of glucocorticoid and mineralocorticoid receptors and 11beta-hydroxysteroid dehydrogenases in human and rat ocular tissues.

Effects of Gonadectomy on Glucocorticoid Metabolism in Obese Zucker Rats

Effects of Peroxisome Proliferator-Activated Receptor-α and -γ Agonists on 11β-Hydroxysteroid Dehydrogenase Type 1 in Subcutaneous Adipose Tissue in Men

Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with Type 2 diabetes with and without fatty liver

Effects of proportions of dietary macronutrients on glucocorticoid metabolism in diet-induced obesity in rats

Enduring effects of severe developmental adversity, including nutritional deprivation, on cortisol metabolism in aging Holocaust survivors

Estrogens and Glucocorticoids in Mammary Adipose Tissue: Relationships with Body Mass Index and Breast Cancer Features

Exploring the Temporal Relation between Body Mass Index and Corticosteroid Metabolite Excretion in Childhood

Future technology insight: mass spectrometry imaging as a tool in drug research and development

Gas chromatography tandem mass spectrometry offers advantages for urinary steroids analysis.

Glucocorticoid metabolism within superficial subcutaneous rather than visceral adipose tissue is associated with features of the metabolic syndrome in South African women.

Glucocorticoids are lower at delivery in maternal, but not cord blood of obese pregnancies

Glucocorticoids turn over slowly in human adipose tissue in vivo

Heritability of Cortisol Production and Metabolism Throughout Adolescence

Higher Insulin Resistance and Adiposity in Postmenopausal Women With Breast Cancer Treated With Aromatase Inhibitors

Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study

Increased A-ring reduction of glucocorticoids in obese Zucker rats: effects of insulin sensitization.

Increased glucocorticoid activity in men with cardiovascular risk factors

Increased glucocorticoid production and altered cortisol metabolism in women with mild to moderate Alzheimer's disease.

Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone.

Increased skeletal muscle 11βHSD1 mRNA is associated with lower muscle strength in ageing.

Increased whole-body and sustained liver cortisol regeneration by 11beta-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target for enzyme inhibition ⬇️

Influence of gender and body composition on glucocorticoid metabolism in middle-aged humans

Intra-adipose sex steroid metabolism and body fat distribution in idiopathic human obesity

Is there a gender difference in the associations of birthweight and adult hypothalamic-pituitary-adrenal axis activity?

It takes two to tango: dimerisation of glucocorticoid receptor and its anti-inflammatory functions.

Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism.

Long-Term Stability of Cortisol Production and Metabolism Throughout Adolescence: Longitudinal Twin Study

Mapping endocrine networks by stable isotope tracing

Mass spectrometry imaging for dissecting steroid intracrinology within target tissues

Maternal Glucocorticoid Metabolism Across Pregnancy: A Potential Mechanism Underlying Fetal Glucocorticoid Exposure

Measurement of tamsulosin in human serum by liquid chromatography-tandem mass spectrometry.

Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: implications for the pathogenesis of steatohepatitis ⬇️

Obesity and Gender Influence Cortisol Secretion and Metabolism in Man ⬇️

Physiological and pathophysiological applications of sensitive ELISA methods for urinary deoxycorticosterone and corticosterone in rodents.

Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia.

Prenatal stress reduces postnatal neurogenesis in rats selectively bred for high, but not low, anxiety: possible key role of placental 11beta-hydroxysteroid dehydrogenase type 2.

Relative adrenal insufficiency in mice deficient in 5α-reductase 1

Renal sodium retention in cirrhotic rats depends on glucocorticoid-mediated activation of mineralocorticoid receptor due to decreased renal 11beta-HSD-2 activity

Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice

Sexual dimorphism in cortisol metabolism throughout pubertal development: a longitudinal study

Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry

The postprandial rise in plasma cortisol in men is mediated by macronutrient-specific stimulation of adrenal and extra-adrenal cortisol production

The role of corticosterone in human hypothalamic-pituitary-adrenal axis feedback.

The role of glucocorticoids in sodium retention in cirrhotic patients: a double blind, randomized, crossover study

Tissue production of cortisol by 11beta-hydroxysteroid dehydrogenase type 1 and metabolic disease.

Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

Tissue-specific dysregulation of 11β-hydroxysteroid dehydrogenase type 1 in overweight/obese women with polycystic ovary syndrome compared with weight-matched controls