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A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"?

artículo científico publicado en 2016

A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals

artículo científico publicado en 2015

A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology

artículo científico publicado en 2016

A common CD4 gene variant is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers

artículo científico publicado en 2009

A comparative analysis of gene expression patterns and cell phenotypes between cervical and peripheral blood mononuclear cells

artículo científico publicado en 2009

A randomized controlled trial of HIV therapeutic vaccination using ALVAC with or without Remune

artículo científico publicado el 27 de marzo de 2011

A randomized controlled trial of palifermin (recombinant human keratinocyte growth factor) for the treatment of inadequate CD4+ T-lymphocyte recovery in patients with HIV-1 infection on antiretroviral therapy

artículo científico publicado en 2014

A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials

scientific article published on 01 August 2019

Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy

artículo científico publicado en 2014

Adjuvant Dependent Mucosal V2 Responses and RAS Activation in Vaccine Induced Protection from SIVmac251 Acquisition.

artículo científico publicado en 2014

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

artículo científico publicado en 2016

An open-ended plea for the development of a global database of HIV vaccine responses

artículo científico publicado en 2012

Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus

artículo científico publicado en 2016

Atorvastatin reduces T-cell activation and exhaustion among HIV-infected cART-treated suboptimal immune responders in Uganda: a randomised crossover placebo-controlled trial

artículo científico publicado en 2015

Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs

artículo científico publicado en 2013

Beyond adjuvants: Antagonizing inflammation to enhance vaccine immunity

artículo científico

CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms.

artículo científico publicado en 2004

CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.

artículo científico publicado en 2016

CTLA-4+PD-1- Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

artículo científico publicado en 2017

Caspase-3 is a component of Fas death-inducing signaling complex in lipid rafts and its activity is required for complete caspase-8 activation during Fas-mediated cell death

artículo científico publicado en 2004

Characterization of transcription factor phenotypes within antigen-specific CD4+ T cells using qualitative multiplex single-cell RT-PCR

artículo científico publicado en 2013

Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation

artículo científico publicado en 2011

Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells

artículo científico publicado en 2006

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C

artículo científico publicado en 2012

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C.

artículo científico publicado en 2012

Correction: Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity

artículo científico publicado en 2013

Current topics in HIV-1 pathogenesis: The emergence of deregulated immuno-metabolism in HIV-infected subjects

artículo científico

Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells

artículo científico publicado en 2013

Dendritic cell inhibition is connected to exhaustion of CD8+ T cell polyfunctionality during chronic hepatitis C virus infection

artículo científico publicado en 2010

Differential modulation of CCR5-tropic human immunodeficiency virus-1 transfer from macrophages towards T cells under interleukin-4/interleukin-13 microenvironment

artículo científico publicado en 2010

Diminished Proliferation of Human Immunodeficiency Virus-Specific CD4+T Cells Is Associated with Diminished Interleukin-2 (IL-2) Production and Is Recovered by Exogenous IL-2

artículo científico publicado el 1 de octubre de 2003

Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation

artículo científico publicado en 2013

Down-regulation of CTLA-4 by HIV-1 Nef protein

artículo científico publicado en 2013

Drug resistance mutations and the cellular immune response: a valuable synergy for the development of novel immune therapies

artículo científico publicado en 2007

Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome

artículo científico publicado en 2014

Enhancement of HIV-specific CD8 T cell responses by dual costimulation with CD80 and CD137L.

artículo científico publicado en 2005

Estimate of the total number of CD8+ clonal expansions in healthy adults using a new DNA heteroduplex-tracking assay for CDR3 repertoire analysis

artículo científico publicado en 2003

Evaluation of OX40 ligand as a costimulator of human antiviral memory CD8 T cell responses: comparison with B7.1 and 4-1BBL.

artículo científico publicado en 2005

Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells

artículo científico publicado en 2011

Follicular CD4 T Helper Cells As a Major HIV Reservoir Compartment: A Molecular Perspective.

artículo científico publicado en 2018

Foxo3a: an integrator of immune dysfunction during HIV infection

artículo científico publicado en 2012

FuGEFlow: data model and markup language for flow cytometry

artículo científico publicado en 2009

GenePattern flow cytometry suite

artículo científico publicado el 3 de julio de 2013

HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses

artículo científico publicado en 2016

HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal

artículo científico publicado en 2017

HIV vaccine candidate activation of hypoxia and the inflammasome in CD14 monocytes is associated with a decreased risk of SIV acquisition

article

HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity

artículo científico publicado en 2003

Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells

scientific article published on 20 May 2009

Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis.

artículo científico publicado en 2017

Human newborn bacille Calmette-Guérin vaccination and risk of tuberculosis disease: a case-control study

artículo científico publicado en 2016

Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach

artículo científico publicado en 2015

Immune activation alters cellular and humoral responses to yellow fever 17D vaccine

artículo científico publicado en 2014

Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection

artículo científico publicado en 2012

Improved NYVAC-based vaccine vectors

artículo científico publicado en 2011

Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors

artículo científico publicado en 2011

Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection

artículo científico publicado en 2003

Inhibition of HIV-1 transmission in trans from dendritic cells to CD4+ T lymphocytes by natural antibodies to the CRD domain of DC-SIGN purified from breast milk and intravenous immunoglobulins

artículo científico publicado en 2007

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

artículo científico publicado en 2017

Interleukin-7 promotes HIV persistence during antiretroviral therapy

artículo científico publicado en 2013

Intrinsic Role of FoxO3a in the Development of CD8+ T Cell Memory

artículo científico publicado el 31 de diciembre de 2012

Kynurenine Reduces Memory CD4 T-Cell Survival by Interfering with Interleukin-2 Signaling Early during HIV-1 Infection

artículo científico publicado en 2016

Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection

artículo científico publicado en 2008

Lymphoid tissue fibrosis is associated with impaired vaccine responses

artículo científico publicado en 2018

Maternal BCG scar is associated with increased infant proinflammatory immune responses

artículo científico publicado en 2016

Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state

artículo científico publicado en 2012

Mucosal Regulatory T Cells and T Helper 17 Cells in HIV-Associated Immune Activation

artículo científico publicado en 2016

Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate

article

Myeloid dendritic cells induce HIV-1 latency in non-proliferating CD4+ T cells

artículo científico publicado en 2013

Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation

artículo científico publicado en 2015

Next generation DNA vaccines for HIV-1.

artículo científico publicado en 2002

Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors

artículo científico publicado en 2017

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4 T cells from ART-suppressed individuals

article

Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy

artículo científico publicado en 2022

Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection

artículo científico publicado en 2009

Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection

artículo científico publicado en 2002

Poly(I:C) and Lipopolysaccharide Innate Sensing Functions of Circulating Human Myeloid Dendritic Cells Are Affected In Vivo in Hepatitis C Virus-Infected Patients

artículo científico publicado en 2007

Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection

artículo científico publicado en 2012

Programmed death 1: a critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections

artículo científico publicado en 2007

Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease

artículo científico publicado en 2014

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

artículo científico publicado en 2010

Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection

artículo científico publicado en 2014

Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys

artículo científico publicado en 2016

Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles

artículo científico publicado en 2007

Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques

artículo científico publicado en 2018

Residual immune dysregulation syndrome in treated HIV infection

artículo científico publicado en 2013

Sequential Infection with Common Pathogens Promotes Human-like Immune Gene Expression and Altered Vaccine Response

artículo científico publicado en 2016

Short Communication: Human Immunodeficiency Virus Rebound in Blood and Seminal Plasma Following Discontinuation of Antiretroviral Therapy

artículo científico publicado el 25 de septiembre de 2012

Standardization of cytokine flow cytometry assays

artículo científico publicado en 2005

Support for the RV144 HIV vaccine trial.

artículo científico publicado en 2004

Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.

artículo científico publicado en 2012

Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity

artículo científico publicado en 2013

Systems biology and the quest for correlates of protection to guide the development of an HIV vaccine

artículo científico publicado en 2016

Systems biology in understanding HIV pathogenesis and guiding vaccine development

artículo científico publicado en 2012

TCR γ Chain Expression on Human Peripheral Blood T Lymphocytes

Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection

artículo científico publicado en 2013

Th17 lineage commitment and HIV-1 pathogenesis

artículo científico publicado en 2010

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?

artículo científico publicado en 2008

The immunological synapse: the gateway to the HIV reservoir

artículo científico publicado en 2013

The interferon paradox: can inhibiting an antiviral mechanism advance an HIV cure?

artículo científico publicado en 2016

The sooner the better: innate immunity as a path toward the HIV cure

artículo científico publicado en 2016

Tn-MUC1 DC Vaccination of Rhesus Macaques and a Phase I/II Trial in Patients with Nonmetastatic Castrate-Resistant Prostate Cancer

artículo científico publicado en 2016

Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection

artículo científico publicado en 2008

Transmission and long-term stability of compensated CD8 escape mutations

artículo científico publicado en 2008

Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity

artículo científico publicado en 2012

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

artículo científico publicado en 2006