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Lista de obras de E C Hirsch

A new model to study compensatory mechanisms in MPTP-treated monkeys exhibiting recovery

artículo científico publicado en 2007

Activation of the subventricular zone in multiple sclerosis: evidence for early glial progenitors.

artículo científico publicado en 2007

Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

artículo científico publicado en 2012

Altered regulation of iron transport and storage in Parkinson's disease.

artículo científico publicado en 2006

Alzheimer's disease: is the decrease of the cholinergic innervation of the hippocampus related to intrinsic hippocampal pathology?

artículo científico publicado el 1 de enero de 1992

An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease.

artículo científico publicado en 1999

Analysis of monocyte infiltration in MPTP mice reveals that microglial CX3CR1 protects against neurotoxic over-induction of monocyte-attracting CCL2 by astrocytes

artículo científico publicado en 2017

Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons

artículo científico publicado en 2007

Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging

artículo científico publicado el 1 de julio de 1997

Autoradiographic study of [125I]epidermal growth factor-binding sites in the mesencephalon of control and parkinsonian brains post-mortem

scientific article published on 01 November 1993

Behavioral consequences of bicuculline injection in the subthalamic nucleus and the zona incerta in rat.

artículo científico publicado en 2002

Behavioral recovery in MPTP-treated monkeys: neurochemical mechanisms studied by intrastriatal microdialysis.

artículo científico publicado en 2008

Biochemistry of Parkinson's disease with special reference to the dopaminergic systems.

artículo científico publicado en 1994

CD95 (APO-1/Fas) and Parkinson's disease

artículo científico publicado en 1998

Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

artículo científico publicado en 2000

Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis.

artículo científico publicado en 2001

Changes in GAD67 mRNA expression evidenced by in situ hybridization in the brain of R6/2 transgenic mice.

artículo científico publicado en 2003

Cholinergic neuronal loss in the globus pallidus of Alzheimer disease patients

artículo científico publicado el 25 de febrero de 1991

Cigarette smoke and nicotine protect dopaminergic neurons against the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Parkinsonian toxin.

artículo científico publicado en 2003

Consequence of nigrostriatal denervation and L-dopa therapy on the expression of glutamic acid decarboxylase messenger RNA in the pallidum

artículo científico publicado en 1996

Consequences of dopaminergic denervation on the metabolic activity of the cortical neurons projecting to the subthalamic nucleus in the rat.

artículo científico publicado en 2002

Consequences of nigrostriatal denervation on the functioning of the basal ganglia in human and nonhuman primates: an in situ hybridization study of cytochrome oxidase subunit I mRNA

artículo científico publicado en 1997

Consequences of nigrostriatal denervation on the gamma-aminobutyric acidic neurons of substantia nigra pars reticulata and superior colliculus in parkinsonian syndromes

artículo científico publicado en 1996

Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase

artículo científico publicado en 2006

Decreased choline acetyltransferase mRNA expression in the nucleus basalis of Meynert in Alzheimer disease: an in situ hybridization study

artículo científico publicado el 15 de octubre de 1992

Decreased tyrosine hydroxylase content in the dopaminergic neurons of MPTP-intoxicated monkeys: effect of levodopa and GM1 ganglioside therapy

artículo científico publicado en 1994

Differential vulnerability to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine of dopaminergic and cholinergic neurons in the monkey mesopontine tegmentum

scientific article published on 01 October 1993

Distribution and morphology of nigral axons projecting to the thalamus in primates

artículo científico publicado en 2002

Distribution of ataxin-7 in normal human brain and retina

article

Does loss of nerve growth factor receptors precede loss of cholinergic neurons in Alzheimer's disease? An autoradiographic study in the human striatum and basal forebrain

artículo científico publicado en 1992

Does neuromelanin contribute to the vulnerability of catecholaminergic neurons in monkeys intoxicated with MPTP?

scientific article published on 01 September 1993

Does oxidative stress participate in nerve cell death in Parkinson's disease?

artículo científico publicado en 1993

Donepezil induces a cholinergic sprouting in basocortical degeneration.

artículo científico publicado en 2007

Dopamine depletion impairs precursor cell proliferation in Parkinson disease.

artículo científico publicado en 2004

Dopamine, tremor, and Parkinson's disease

artículo científico publicado el 11 de julio de 1992

Dopaminergic neurons degenerate by apoptosis in Parkinson's disease.

artículo científico publicado en 1999

Dopaminergic neurons reduced to silence by oxidative stress: an early step in the death cascade in Parkinson's disease?

artículo científico publicado en 2006

Dopaminergic substantia nigra neurons project topographically organized to the subventricular zone and stimulate precursor cell proliferation in aged primates.

artículo científico publicado en 2006

Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

artículo científico publicado en 2003

Dyskinesia in Parkinson's disease: a clinical complication and an open scientific question

artículo científico publicado en 2018

Editorial

scientific article published on 27 July 2010

Effect of mitochondrial complex I inhibition on Fe–S cluster protein activity

artículo científico publicado el 6 de mayo de 2011

Effects of L-DOPA-therapy on dopamine D2 receptor mRNA expression in the striatum of MPTP-intoxicated parkinsonian monkeys

artículo científico publicado en 1996

Evidence for a dopaminergic innervation of the pedunculopontine nucleus in monkeys, and its drastic reduction after MPTP intoxication.

artículo científico publicado en 2009

Evidence of active microglia in substantia nigra pars compacta of parkinsonian monkeys 1 year after MPTP exposure.

artículo científico publicado en 2004

Evolution of changes in neuronal activity in the subthalamic nucleus of rats with unilateral lesion of the substantia nigra assessed by metabolic and electrophysiological measurements

artículo científico publicado en 2000

Flavaglines as potent anticancer and cytoprotective agents

artículo científico publicado en 2012

Functional activity of zona incerta neurons is altered after nigrostriatal denervation in hemiparkinsonian rats

artículo científico publicado en 2000

GM-1 ganglioside promotes the recovery of surviving midbrain dopaminergic neurons in MPTP-treated monkeys

artículo científico publicado en 1993

Gait disorders in parkinsonian monkeys with pedunculopontine nucleus lesions: a tale of two systems.

artículo científico publicado en 2013

Glial cells and Parkinson's disease.

artículo científico publicado en 2000

Glial cells and inflammation in Parkinson's disease: a role in neurodegeneration?

artículo científico publicado en 1998

Glucocerebrosidase deficiency and mitochondrial impairment in experimental Parkinson disease.

artículo científico publicado en 2015

Glucocorticoid receptor in astrocytes regulates midbrain dopamine neurodegeneration through connexin hemichannel activity

scientific article published on 13 July 2018

Glutaredoxin 1 Downregulation in the Substantia Nigra Leads to Dopaminergic Degeneration in Mice

artículo científico publicado en 2020

Granulocyte colony-stimulating factor is not protective against selective dopaminergic cell death in vitro.

artículo científico publicado en 2005

Hepcidin attenuates amyloid beta-induced inflammatory and pro-oxidant responses in astrocytes and microglia.

artículo científico publicado en 2017

Heterogeneous intracellular localization and expression of ataxin-3.

artículo científico publicado en 1998

High affinity neurotrophin receptors in cholinergic neurons in the human brain

artículo científico publicado en 1994

How to improve neuroprotection in Parkinson's disease?

scientific article published on January 2007

How to judge animal models of Parkinson's disease in terms of neuroprotection.

artículo científico publicado en 2006

In search of innovative therapeutics for neuropsychiatric disorders: the case of neurodegenerative diseases.

artículo científico publicado en 2014

Increased mRNA expression of cytochrome oxidase in dorsal raphe nucleus of depressive suicide victims.

artículo científico publicado en 2008

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.

artículo científico publicado en 2008

Inflammation and dopaminergic neuronal loss in Parkinson's disease: a complex matter.

artículo científico publicado en 2003

Internal pallidum and substantia nigra control different parts of the mesopontine reticular formation in primate

artículo científico publicado el 5 de abril de 2011

Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin

artículo científico publicado en 2006

Iron metabolism and Parkinson's disease

artículo científico publicado el 1 de enero de 1998

Is the vulnerability of neurons in the substantia nigra of patients with Parkinson's disease related to their neuromelanin content?

artículo científico publicado el 1 de septiembre de 1992

Journal of Neural Transmission: a scientific journal devoted since 1950 to the translation of neuroscience into clinical practice

artículo científico publicado en 2019

Levodopa but not ropinirole induces an internalization of D1 dopamine receptors in parkinsonian rats.

artículo científico publicado en 2002

Localization of D1a dopamine receptors on cell bodies and axonal endings in the substantia nigra pars reticulata of the rat

scientific journal article

Long-term outcome in neuroZika: When biological diagnosis matters

artículo científico publicado en 2019

Loss of striatal high affinity NGF binding sites in progressive supranuclear palsy but not in Parkinson's disease

scientific article published on 01 November 1994

Low affinity nerve growth factor receptor, adrenal transplant and Parkinson's disease

scientific article published on 01 December 1993

MFGE8 does not orchestrate clearance of apoptotic neurons in a mouse model of Parkinson's disease.

artículo científico publicado en 2012

Mechanism and consequences of nerve cell death in Parkinson's disease.

artículo científico publicado en 1999

Metabolic activity of cerebellar and basal ganglia-thalamic neurons is reduced in parkinsonism.

artículo científico publicado en 2007

Metabolic activity of excitatory parafascicular and pedunculopontine inputs to the subthalamic nucleus in a rat model of Parkinson's disease.

artículo científico publicado en 2000

Metabolic activity of the basal ganglia in parkinsonian syndromes in human and non-human primates: a cytochrome oxidase histochemistry study

artículo científico publicado en 1996

Metabolic effects of nigrostriatal denervation in basal ganglia.

artículo científico publicado en 2000

Mitochondrial free calcium levels (Rhod-2 fluorescence) and ultrastructural alterations in neuronally differentiated PC12 cells during ceramide-dependent cell death

artículo científico publicado en 2000

NMDA receptor GluN2A/GluN2B subunit ratio as synaptic trait of levodopa-induced dyskinesias: from experimental models to patients.

artículo científico publicado en 2015

Neurochemical correlates of parkinsonism. Role of dopaminergic lesions

artículo científico publicado el 1 de enero de 1997

Neuroinflammation in Parkinson's disease.

artículo científico

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

artículo científico publicado en 2009

Neuroinflammatory processes in Parkinson's disease

scientific article published on 01 June 2005

Neuroinflammatory processes in Parkinson's disease.

artículo científico publicado en 2003

Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson's disease.

artículo científico publicado en 2003

Neuronal distribution of intranuclear inclusions in Huntington's disease with adult onset.

artículo científico publicado en 1998

Neuronal plasticity and Parkinson disease

artículo científico publicado el 1 de febrero de 1995

Neuroprotection of dopamine neurons by xenon against low-level excitotoxic insults is not reproduced by other noble gases

artículo científico publicado en 2019

Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca2+.

artículo científico publicado en 2011

Neuroprotective and neurorestorative potential of xenon.

artículo científico publicado en 2016

New striatal dopamine neurons in MPTP-treated macaques result from a phenotypic shift and not neurogenesis.

artículo científico publicado en 2006

Nitric oxide synthase and neuronal vulnerability in Parkinson's disease.

artículo científico publicado en 1996

Nondopaminergic neurons in Parkinson's disease.

artículo científico publicado en 2003

Normal and pathological gait: what we learn from Parkinson's disease: Figure 1

artículo científico publicado el 29 de junio de 2012

Nuclear translocation of NF-κB in cholinergic neurons of patients with Alzheimerʼs disease

artículo científico publicado el 8 de septiembre de 1997

Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels

artículo científico publicado en 2008

Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

artículo científico publicado en 2003

Parkinson disease: mechanisms of cell death

artículo científico publicado el 1 de diciembre de 2002

Pathogenesis of Parkinson's disease

artículo científico publicado en 2012

Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease.

artículo científico publicado en 2004

Piperazine derivatives as iron chelators: a potential application in neurobiology

artículo científico publicado en 2015

Preservation of midbrain catecholaminergic neurons in very old human subjects

artículo científico publicado en 2000

Proliferation of microglial cells induced by 1-methyl-4-phenylpyridinium in mesencephalic cultures results from an astrocyte-dependent mechanism: role of granulocyte macrophage colony-stimulating factor.

artículo científico publicado en 2005

Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization.

artículo científico publicado en 2009

Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease.

artículo científico publicado en 2002

Quantitative analysis of dopaminergic loss in relation to functional territories in MPTP-treated monkeys.

artículo científico publicado en 2003

Quantitative evaluation of the human subventricular zone.

artículo científico publicado en 2012

Re-evaluation of the functional anatomy of the basal ganglia in normal and Parkinsonian states

artículo científico publicado en 1997

Rescue of mesencephalic dopaminergic neurons in culture by low-level stimulation of voltage-gated sodium channels

artículo científico publicado en 2004

Role of pedunculopontine cholinergic neurons in the vulnerability of nigral dopaminergic neurons in Parkinson's disease

artículo científico publicado en 2015

S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization

scientific article published on 19 December 2018

Seven Solutions for Neuroprotection in Parkinson's Disease

artículo científico publicado en 2020

Sleep disorders in Parkinsonian macaques: effects of L-dopa treatment and pedunculopontine nucleus lesion

artículo científico publicado en 2014

Sparing of orexin-A and orexin-B neurons in the hypothalamus and of orexin fibers in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated macaques

artículo científico publicado en 2014

Special issue in honor of Peter Riederer at the occasion of his 80th birthday

artículo científico publicado en 2022

Specific needs of dopamine neurons for stimulation in order to survive: implication for Parkinson disease.

artículo científico publicado en 2013

Stathmin: cellular localization of a major phosphoprotein in the adult rat and human CNS.

artículo científico publicado en 1993

Striatal expression of glutamic acid decarboxylase gene in Alzheimer's disease.

artículo científico publicado en 1998

Substance P, neurokinins A and B, and synthetic tachykinin peptides protect mesencephalic dopaminergic neurons in culture via an activity-dependent mechanism.

artículo científico publicado en 2005

Ten Unsolved Questions About Neuroinflammation in Parkinson's Disease

artículo científico publicado en 2020

Thalamic neuronal activity in dopamine-depleted primates: evidence for a loss of functional segregation within basal ganglia circuits.

artículo científico publicado en 2005

The Oxygen Paradox, the French Paradox, and age-related diseases.

artículo científico publicado en 2017

The density of [125I]-transferrin binding sites on perikarya of melanized neurons of the substantia nigra is decreased in Parkinson's disease

artículo científico publicado en 1997

The global fight against dementia

artículo científico publicado en 2014

The iron-binding protein lactoferrin protects vulnerable dopamine neurons from degeneration by preserving mitochondrial calcium homeostasis.

artículo científico publicado en 2013

The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism.

artículo científico publicado en 2003

The neurotransmitter noradrenaline rescues septal cholinergic neurons in culture from degeneration caused by low-level oxidative stress.

artículo científico publicado en 2005

The noble gas xenon provides protection and trophic stimulation to midbrain dopamine neurons

artículo científico publicado en 2017

The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration.

artículo científico publicado en 2003

The pallidosubthalamic projection: an anatomical substrate for nonmotor functions of the subthalamic nucleus in primates.

artículo científico publicado en 2005

The role of glial reaction and inflammation in Parkinson's disease.

artículo científico publicado en 2003

The rotenone model of parkinsonism--the five years inspection.

artículo científico publicado en 2006

The sleep-modulating peptide orexin-B protects midbrain dopamine neurons from degeneration, alone or in cooperation with nicotine.

artículo científico publicado en 2014

Tremor-related activity of neurons in the 'motor' thalamus: changes in firing rate and pattern in the MPTP vervet model of parkinsonism.

artículo científico publicado en 2003

Tyrosine kinase B messenger RNA expression in normal human brain and in the substantia nigra of parkinsonian patients: an in situ hybridization study

artículo científico publicado el 1 de octubre de 1998

Ultrastructural localization of parkin in the rat brainstem, thalamus and basal ganglia

scientific journal article

Understanding Dopaminergic Cell Death Pathways in Parkinson Disease

artículo científico publicado en 2016

Xenon-mediated neuroprotection in response to sustained, low-level excitotoxic stress

artículo científico publicado en 2016

[125I]EGF binding in basal ganglia of patients with Parkinson's disease and progressive supranuclear palsy and in MPTP-treated monkeys.

artículo científico publicado en 1998

c-fos protein-like immunoreactivity: distribution in the human brain and over-expression in the hippocampus of patients with Alzheimer's disease

artículo científico publicado el 1 de enero de 1992