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'Unleashed' natural killers hinder HIV.

artículo científico publicado en 2007

A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais

artículo científico publicado en 2011

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells

artículo científico publicado en 2007

Acute HIV infection with rapid progression to AIDS

article

Acute HIV infection with rapid progression to AIDS.

artículo científico publicado en 2010

Acute HIV-1 infection: past lessons, current thinking, future goals

artículo científico publicado en 2008

Alterations in natural killer cell receptor profiles during HIV type 1 disease progression among chronically infected South African adults

artículo científico publicado en 2010

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells

artículo científico publicado en 2008

Antigen-specific NK cell memory in rhesus macaques

artículo científico publicado en 2015

Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: report of 2 cases

artículo científico publicado en 2014

Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope

artículo científico publicado en 2007

Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection

artículo científico publicado en 2007

Brief Report: Increased Frequency of CD39+ CD56bright Natural Killer Cells in HIV-1 Infection Correlates With Immune Activation and Disease Progression

artículo científico publicado en 2016

CD4+ T-cell help enhances NK cell function following therapeutic HIV-1 vaccination

artículo científico publicado en 2014

CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects

artículo científico publicado en 2004

CEACAM1 controls IL-2-dependent regulatory T cell induction in immune-mediated hepatitis

artículo científico publicado en 2018

Can NK cells purge HIV sanctuaries?

artículo científico publicado en 2017

Changes in Natural Killer cell activation and function during primary HIV-1 Infection

artículo científico publicado en 2013

Changes in cytokine levels and NK cell activation associated with influenza

artículo científico publicado en 2011

Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

artículo científico publicado en 2011

Clustering patterns of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1 (HIV-1) proteins reveal imprints of immune evasion on HIV-1 global variation

artículo científico publicado en 2002

Common HIV-1 peptide variants mediate differential binding of KIR3DL1 to HLA-Bw4 molecules

artículo científico publicado en 2011

Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses

artículo científico publicado en 2003

Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides

scientific article published on May 2004

Comprehensive analysis of virus-specific T-cells provides clues for the failure of therapeutic immunization with ALVAC-HIV vaccine

artículo científico publicado en 2011

Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection

artículo científico publicado en 2002

Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes

artículo científico publicado en 2005

Control of human viral infections by natural killer cells

artículo científico publicado en 2013

Coordinate linkage of HIV evolution reveals regions of immunological vulnerability

artículo científico publicado en 2011

DCs and NK cells: critical effectors in the immune response to HIV-1.

artículo científico publicado en 2011

De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection

artículo científico publicado en 2005

Dendritic cells in the circulation of women with preeclampsia demonstrate a pro-inflammatory bias secondary to dysregulation of TLR receptors

artículo científico publicado en 2012

Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infection

scientific journal article

Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus

artículo científico publicado en 2016

Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians

artículo científico publicado en 2004

Differential Immunogenicity of HIV‐1 Clade C Proteins in Eliciting CD8+and CD4+Cell Responses

article

Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes

artículo científico publicado en 2007

Differential regulation of toll-like receptor pathways in acute and chronic HIV-1 infection

artículo científico publicado en 2012

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

artículo científico publicado en 2004

Early preservation of CXCR5+ PD-1+ helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection

artículo científico publicado en 2014

Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection

artículo científico publicado en 2010

Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection

artículo científico publicado en 2010

Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome

artículo científico publicado en 2014

Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

artículo científico publicado en 2016

Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences

artículo científico publicado en 2003

Enhanced immune activation linked to endotoxemia in HIV-1 seronegative MSM.

artículo científico publicado en 2014

Epidemiologically linked transmission of HIV-1 illustrates the impact of host genetics on virological outcome

artículo científico publicado en 2009

Epithelial adhesion molecules can inhibit HIV-1-specific CD8⁺ T-cell functions

artículo científico publicado en 2011

Erratum to: Impact of HIV-1 infection on the feto-maternal crosstalk and consequences for pregnancy outcome and infant health

artículo científico publicado en 2016

Erratum: addendum: HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

scientific article published in Nature

Evasion from NK cell-mediated immune responses by HIV-1 ⬇️

artículo científico publicado en 2012

Evolution of innate and adaptive effector cell functions during acute HIV-1 infection

artículo científico publicado en 2007

Expansion of 2B4+ natural killer (NK) cells and decrease in NKp46+ NK cells in response to influenza

artículo científico publicado en 2011

Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection

artículo científico publicado en 2002

Exposure to HIV-1-encoded Toll-like receptor 8 ligands enhances monocyte response to microbial encoded Toll-like receptor 2/4 ligands

artículo científico publicado en 2010

Factors predicting discordant virological and immunological responses to antiretroviral therapy in HIV-1 clade C infected Zulu/Xhosa in South Africa

artículo científico publicado en 2012

Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire

artículo científico publicado en 2005

Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes

artículo científico publicado en 2015

Frequent and strong antibody-mediated natural killer cell activation in response to HIV-1 Env in individuals with chronic HIV-1 infection

artículo científico publicado en 2012

Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection

artículo científico publicado en 2007

HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity

artículo científico publicado en 2004

HIV-1 adaptation to NK-cell-mediated immune pressure

artículo científico publicado en 2011

HIV-1 infection induces strong production of IP-10 through TLR7/9-dependent pathways

artículo científico publicado en 2013

HIV-1 superinfection

artículo científico publicado en 2003

HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

artículo científico publicado en 2002

HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response

artículo científico publicado en 2005

HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells

artículo científico publicado en 2017

HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha

artículo científico publicado en 2004

HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function

artículo científico publicado en 2011

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.

artículo científico publicado en 2006

HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection

artículo científico publicado en 2009

HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load

artículo científico publicado en 2005

HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function

artículo científico publicado en 2012

Harnessing innate and adaptive immunity for viral vaccine design

artículo científico publicado en 2012

Hepatitis C virus drives increased type I interferon-associated impairments associated with fibrosis severity in antiretroviral treatment-treated HIV-1-hepatitis C virus-coinfected individuals

artículo científico publicado en 2017

High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level

artículo científico publicado en 2005

Hitting HIV where it hurts: an alternative approach to HIV vaccine design

artículo científico publicado en 2006

Human Immunodeficiency Virus 1 and Type I Interferons-Where Sex Makes a Difference

artículo científico publicado en 2017

Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC)

artículo científico publicado en 2007

Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells

scientific article published on 20 May 2009

Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expression

artículo científico publicado en 2016

IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection

artículo científico publicado en 2010

IL-8 responsiveness defines a subset of CD8 T cells poised to kill

artículo científico publicado en 2004

Identification of HIV-1-specific regulatory T-cells using HLA class II tetramers

artículo científico publicado en 2012

Immune activation and HIV: an enduring relationship

artículo científico publicado en 2016

Immune activation and the role of TLRs and TLR agonists in the pathogenesis of HIV-1 infection in the humanized mouse model

artículo científico publicado en 2013

Immune control of HIV-1 after early treatment of acute infection

artículo científico publicado en 2000

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

artículo científico publicado en 2004

Immunodominance of HIV-1-specific CD8(+) T-cell responses in acute HIV-1 infection: at the crossroads of viral and host genetics

artículo científico publicado en 2005

Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality

artículo científico publicado en 2010

Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection

artículo científico publicado en 2006

Impact of blood processing variations on natural killer cell frequency, activation, chemokine receptor expression and function

artículo científico publicado en 2011

Impact of intrapeptide epitope location on CD8 T cell recognition

Impact of maternal HIV-1 infection on the feto-maternal crosstalk and consequences for pregnancy outcome and infant health

artículo científico publicado en 2016

Impairment of CD1d-restricted natural killer T cells in chronic HIV type 1 clade C infection

artículo científico publicado en 2010

Important contribution of p15 Gag-specific responses to the total Gag-specific CTL responses

artículo científico publicado en 2002

Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01.

artículo científico publicado en 2015

Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection

artículo científico publicado en 2003

Innate immune activation enhances hiv acquisition in women, diminishing the effectiveness of tenofovir microbicide gel.

artículo científico publicado en 2012

Innate immune activation in primary HIV-1 infection

artículo científico publicado en 2010

Innate immunity against HIV-1 infection

artículo científico

Interleukin 1-Beta (IL-1β) Production by Innate Cells Following TLR Stimulation Correlates With TB Recurrence in ART-Treated HIV-Infected Patients

artículo científico publicado en 2016

Is There Natural Killer Cell Memory and Can It Be Harnessed by Vaccination? Can Natural Killer and CD8 T Cells Switch Jobs?

artículo científico publicado en 2017

KIR polymorphisms modulate peptide-dependent binding to an MHC class I ligand with a Bw6 motif

artículo científico publicado en 2011

Lack of detectable HIV-1-specific CD8(+) T cell responses in Zambian HIV-1-exposed seronegative partners of HIV-1-positive individuals ⬇️

artículo científico publicado en 2010

Ligand-independent exhaustion of killer immunoglobulin-like receptor-positive CD8+ T cells in human immunodeficiency virus type 1 infection

artículo científico publicado en 2008

Limited durability of viral control following treated acute HIV infection

artículo científico publicado en 2004

Limited immunogenicity of HIV CD8+ T-cell epitopes in acute Clade C virus infection

artículo científico publicado en 2011

Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells

artículo científico publicado en 2004

Loss of HIV-1-specific T-cell responses associated with very rapid HIV-1 disease progression

artículo científico publicado en 2007

Low perforin and elevated SHIP-1 expression is associated with functional anergy of natural killer cells in chronic HIV-1 infection

artículo científico publicado en 2006

MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction

artículo científico publicado en 2010

Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection

artículo científico publicado en 2008

Mutiny or scrutiny: NK cell modulation of DC function in HIV-1 infection

artículo científico publicado en 2011

Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes

artículo científico publicado en 2006

MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands

artículo científico publicado en 2007

NK cell function in HIV-1 infection

artículo científico publicado en 2006

Natural Killer Cell Interactions with Classical and Non-Classical Human Leukocyte Antigen Class I in HIV-1 Infection

artículo científico publicado en 2017

Natural killer cell function in women at high risk for HIV acquisition: insights from a microbicide trial

artículo científico publicado en 2012

Natural killer cells in immunodefense against infective agents

artículo científico publicado en 2008

Natural killer cells: tolerance to self and innate immunity to viral infection and malignancy

scientific article published on 14 October 2009

Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation

artículo científico publicado en 2015

Neither microbial translocation nor TLR responsiveness are likely explanations for preexisting immune activation in women who subsequently acquired HIV in CAPRISA 004

artículo científico publicado en 2013

Novel KIR3DL1 alleles and their expression levels on NK cells: convergent evolution of KIR3DL1 phenotype variation?

scientific article published on May 2008

Novel approach for differential diagnosis of HIV infections in the face of vaccine-generated antibodies: utility for detection of diverse HIV-1 subtypes

artículo científico publicado en 2006

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe

artículo científico publicado en 2016

Polymorphisms in interferon regulatory factor 7 reduce interferon-α responses of plasmacytoid dendritic cells to HIV-1.

artículo científico publicado en 2011

Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China

artículo científico publicado en 2012

Preservation HIV-1-specific IFNγ+ CD4+ T-cell responses in breakthrough infections after exposure to tenofovir gel in the CAPRISA 004 microbicide trial

artículo científico publicado en 2012

Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue

artículo científico publicado en 2012

Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1.

artículo científico publicado en 2008

Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice

artículo científico publicado en 2012

Rapid ex vivo isolation and long-term culture of human Th17 cells

artículo científico publicado en 2008

Rapid loss of dendritic cell and monocyte responses to TLR ligands following venipuncture

artículo científico publicado en 2008

Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution

artículo científico publicado en 2006

Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles

artículo científico publicado en 2007

Reduced Expression of Siglec-7, NKG2A and CD57 on Terminally Differentiated CD56-CD16+ NK Cell Subset is associated with NK Cell Dysfunction in Chronic HIV-1 clade C Infection

artículo científico publicado en 2017

Regulatory T cell frequencies do not correlate with breadth or magnitude of HIV-1-specific T cell responses

artículo científico publicado en 2012

Relative dominance of Env-gp41-specific cytotoxic T lymphocytes responses in HIV-1 advanced infection

artículo científico publicado en 2008

Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control

artículo científico publicado en 2006

Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression

artículo científico publicado en 2015

Rev activity determines sensitivity of HIV-1-infected primary T cells to CTL killing

artículo científico publicado en 2003

Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities

artículo científico publicado en 2017

Second European Round Table on the Future Management of HIV: 10-11 October 2014, Barcelona, Spain

artículo científico publicado en 2015

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa

artículo científico publicado en 2015

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

artículo científico publicado en 2004

Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection

artículo científico publicado en 2007

Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution

artículo científico publicado en 2005

Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03:04 and modulate primary natural killer cell function

artículo científico publicado en 2014

Sex and gender differences in HIV-1 infection

artículo científico publicado en 2016

Sex differences in HIV-1-mediated immunopathology

artículo científico publicado en 2016

Sex differences in infectious diseases and their clinical consequences

artículo científico publicado en 2015

Sex differences in infectious diseases-common but neglected

artículo científico publicado en 2014

Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1.

artículo científico publicado en 2009

Short communication: CD8(+) T cell polyfunctionality profiles in progressive and nonprogressive pediatric HIV type 1 infection

artículo científico publicado en 2011

Single-stranded RNA derived from HIV-1 serves as a potent activator of NK cells

artículo científico publicado en 2007

Stable Frequencies of HLA-C03:04/Peptide-Binding KIR2DL2/3 Natural Killer Cells Following Vaccination

Standardization of cytokine flow cytometry assays

artículo científico publicado en 2005

Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV.

artículo científico publicado en 2017

T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily

article

TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment

artículo científico publicado en 2014

Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection

artículo científico publicado en 2013

The STEP study provides a hint that vaccine induction of the right CD8+ T cell responses can facilitate immune control of HIV.

artículo científico publicado en 2011

The X awakens: multifactorial ramifications of sex-specific differences in HIV-1 infection

artículo científico publicado en 2016

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

artículo científico publicado en 2010

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design

artículo científico publicado en 2005

Toll-like receptor signaling in HIV-1 infection: a potential target for therapy?

artículo científico publicado en 2007

Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands

artículo científico publicado en 2008

Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection

artículo científico publicado en 2012

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