Lista de obras -

A CD8α- Subset of CD4+ SLAMF7+ Cytotoxic T Cells is Expanded in Patients with IgG4-Related Disease and Decreases following Glucocorticoid Treatment.

artículo científico publicado en 2018

A dual role for genetically modified lymphocytes in cancer immunotherapy.

artículo científico publicado en 2012

Adoptive T-cell therapy for cancer: The era of engineered T cells

artículo científico publicado en 2015

Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation

artículo científico

Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica

artículo científico publicado en 2014

Antitumor effects of HSV-TK engineered donor lymphocytes after allogeneic stem-cell transplantation

artículo científico publicado en 2007

Beneficial role of CD8+ T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting

artículo científico publicado en 2018

Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

artículo científico publicado en 2019

CD4+ Memory Stem T Cells Recognizing Citrullinated Epitopes Are Expanded in Patients With Rheumatoid Arthritis and Sensitive to Tumor Necrosis Factor Blockade

scientific article published on 05 March 2020

Cell-based strategies to manage leukemia relapse: efficacy and feasibility of immunotherapy approaches

artículo científico publicado en 2014

Changes in T-cell responses against human herpesvirus-8 correlate with the disease course of iatrogenic Kaposi's sarcoma in a patient with undifferentiated arthritis.

artículo científico publicado en 2008

Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion from the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation

artículo científico publicado en 2018

Clinical pharmacology of CAR-T cells: Linking cellular pharmacodynamics to pharmacokinetics and antitumor effects.

artículo científico publicado en 2015

Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)-an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Tran

scientific article published on 15 May 2019

Concomitant Tumor and Minor Histocompatibility Antigen–Specific Immunity Initiate Rejection and Maintain Remission from Established Spontaneous Solid Tumors

artículo científico publicado en 2010

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.

artículo científico publicado en 2006

Cytokine-induced killer cells engineered with exogenous T-cell receptors directed against melanoma antigens: enhanced efficacy of effector cells endowed with a double mechanism of tumor recognition

artículo científico publicado en 2015

Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors

scientific article published on 27 August 2019

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

artículo científico publicado en 2006

Early molecular diagnosis of aspergillosis in a patient with acute myeloid leukaemia

artículo científico publicado en 2014

Early recovery of CMV immunity after HLA-haploidentical hematopoietic stem cell transplantation as a surrogate biomarker for a reduced risk of severe infections overall

artículo científico publicado en 2015

Expression of HSV-TK suicide gene in primary T lymphocytes: the dog as a preclinical model.

artículo científico publicado en 2000

Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation.

artículo científico publicado en 2007

Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation.

artículo científico publicado en 2015

Genetic engineering of T cells for the immunotherapy of haematological malignancies.

artículo científico

Genetic modification of T cells

artículo científico publicado en 2011

Genetically Modified Donor Leukocyte Transfusion and Graft-Versus-Leukemia Effect After Allogeneic Stem Cell Transplantation ⬇️

artículo científico publicado el 30 de marzo de 2011

Genomic loss of patient-specific HLA in acute myeloid leukemia relapse after well-matched unrelated donor HSCT.

artículo científico publicado en 2012

Handling, processing and disposal of stem cell products in Europe: A survey by the cellular therapy and immunobiology working party of the European Society for Blood and Marrow Transplantation

artículo científico publicado en 2018

Haploidentical HSCT: a 15-year experience at San Raffaele.

artículo científico publicado en 2015

Hematopoietic SCT in Europe 2013: recent trends in the use of alternative donors showing more haploidentical donors but fewer cord blood transplants.

artículo científico publicado en 2015

Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually.

artículo científico publicado en 2016

Hematopoietic stem cell transplantation in its 60s: A platform for cellular therapies.

artículo científico publicado en 2018

Human Herpesvirus 6 Infection Following Haploidentical Transplantation: Immune Recovery and Outcome.

artículo científico publicado en 2016

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors.

artículo científico publicado en 2012

Immune monitoring in allogeneic hematopoietic stem cell transplant recipients: a survey from the EBMT-CTIWP.

artículo científico publicado en 2018

Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

scientific article published on 25 March 2019

Immunotherapy of human viral and malignant diseases with genetically modified T-cell clones.

artículo científico publicado en 2000

Impact of drug development on the use of stem cell transplantation: a report by the European Society for Blood and Marrow Transplantation (EBMT).

artículo científico publicado en 2016

Improving the safety of cell therapy with the TK-suicide gene

artículo científico publicado en 2015

In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells

artículo científico publicado en 2015

Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation.

artículo científico publicado en 2014

Indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2019.

artículo científico publicado en 2019

Inflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMD

artículo científico publicado en 2014

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study.

artículo científico publicado en 2009

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy

artículo científico publicado en 2015

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy.

artículo científico publicado en 2016

Long term follow up of patients after allogeneic stem cell transplantation and transfusion of HSV-TK transduced T-cells.

artículo científico publicado en 2015

Loss of mismatched HLA in leukemia after stem-cell transplantation.

artículo científico publicado en 2009

Manufacturing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers Affiliated with the European Society for Blood and Marrow Transplantation

scientific article published on 20 July 2018

Missing HLA C group 1 ligand in patients with AML and MDS is associated with reduced risk of relapse and better survival after allogeneic stem cell transplantation with fludarabine and treosulfan reduced toxicity conditioning.

artículo científico publicado en 2017

Modulation of GvHD by suicide-gene transduced donor T lymphocytes: clinical applications in mismatched transplantation.

artículo científico publicado en 2005

Molecular modification of idiotypes from B-cell lymphomas for expression in mature dendritic cells as a strategy to induce tumor-reactive CD4+ and CD8+ T-cell responses.

artículo científico publicado en 2005

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

artículo científico publicado en 2018

NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: dynamics and clinical implications.

artículo científico publicado en 2017

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.

artículo científico publicado en 2017

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

artículo científico publicado en 2018

Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer.

artículo científico publicado en 1994

Post-transplantation Cyclophosphamide and Sirolimus after Haploidentical Hematopoietic Stem Cell Transplantation Using a Treosulfan-based Myeloablative Conditioning and Peripheral Blood Stem Cells

artículo científico publicado en 2015

Potential and limitations of HSV-TK-transduced donor peripheral blood lymphocytes after allo-BMT

artículo científico publicado en 1997

Predicting the Clinical Outcome of Allogeneic Hematopoietic Stem Cell Transplantation: The Long and Winding Road toward Validated Immune Biomarkers.

artículo científico

Prevention and treatment of relapse after stem cell transplantation by cellular therapies

artículo científico publicado en 2018

Proceedings From the Fourth Haploidentical Stem Cell Transplantation Symposium - HAPLO2016, San Diego, California, December 1, 2016.

artículo científico publicado en 2018

Restoring Natural Killer Cell Immunity against Multiple Myeloma in the Era of New Drugs.

artículo científico publicado en 2017

Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.

artículo científico publicado en 2006

Safety of retroviral gene marking with a truncated NGF receptor

scientific article published on 01 April 2003

Secondary malignancies after high-dose chemotherapy in germ cell tumor patients: a 34-year retrospective study of the European Society for Blood and Marrow Transplantation (EBMT).

artículo científico publicado en 2018

Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.

artículo científico publicado en 2014

Site-specific integration and tailoring of cassette design for sustainable gene transfer.

artículo científico publicado en 2011

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

artículo científico publicado en 2018

T memory stem cells in health and disease.

artículo científico publicado en 2017

T-cell suicide gene therapy prompts thymic renewal in adults after hematopoietic stem cell transplantation.

artículo científico publicado en 2012

Targeted genome editing in human repopulating haematopoietic stem cells

artículo científico publicado en 2014

Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation.

artículo científico publicado en 2008

The hidden (and lazy) TCR

artículo científico publicado en 2009

Therapeutic and diagnostic applications of minor histocompatibility antigen HA-1 and HA-2 disparities in allogeneic hematopoietic stem cell transplantation: a survey of different populations.

artículo científico publicado en 2006

Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory.

artículo científico publicado en 2015

Transcriptional enhancers induce insertional gene deregulation independently from the vector type and design.

artículo científico publicado en 2009

Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes.

artículo científico publicado en 2004

Trick to treat: tricking the thymus to treat cancer.

artículo científico publicado en 2013

Use of TK-cells in haploidentical hematopoietic stem cell transplantation.

artículo científico publicado en 2012

Use of haploidentical stem cell transplantation continues to increase: the 2015 European Society for Blood and Marrow Transplant activity survey report.

artículo científico publicado en 2017

When transgenes shape immunity: cancer immune-gene therapy.

artículo científico publicado en 2012

Lista de obras de

A CD8α- Subset of CD4+ SLAMF7+ Cytotoxic T Cells is Expanded in Patients with IgG4-Related Disease and Decreases following Glucocorticoid Treatment.

A dual role for genetically modified lymphocytes in cancer immunotherapy.

Adoptive T-cell therapy for cancer: The era of engineered T cells

Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation

Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica

Antitumor effects of HSV-TK engineered donor lymphocytes after allogeneic stem-cell transplantation

Beneficial role of CD8+ T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting

Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

CD4+ Memory Stem T Cells Recognizing Citrullinated Epitopes Are Expanded in Patients With Rheumatoid Arthritis and Sensitive to Tumor Necrosis Factor Blockade

Cell-based strategies to manage leukemia relapse: efficacy and feasibility of immunotherapy approaches

Changes in T-cell responses against human herpesvirus-8 correlate with the disease course of iatrogenic Kaposi's sarcoma in a patient with undifferentiated arthritis.

Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion from the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation

Clinical pharmacology of CAR-T cells: Linking cellular pharmacodynamics to pharmacokinetics and antitumor effects.

Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)-an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Tran

Concomitant Tumor and Minor Histocompatibility Antigen–Specific Immunity Initiate Rejection and Maintain Remission from Established Spontaneous Solid Tumors

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.

Cytokine-induced killer cells engineered with exogenous T-cell receptors directed against melanoma antigens: enhanced efficacy of effector cells endowed with a double mechanism of tumor recognition

Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

Early molecular diagnosis of aspergillosis in a patient with acute myeloid leukaemia

Early recovery of CMV immunity after HLA-haploidentical hematopoietic stem cell transplantation as a surrogate biomarker for a reduced risk of severe infections overall

Expression of HSV-TK suicide gene in primary T lymphocytes: the dog as a preclinical model.

Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation.

Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation.

Genetic engineering of T cells for the immunotherapy of haematological malignancies.

Genetic modification of T cells

Genetically Modified Donor Leukocyte Transfusion and Graft-Versus-Leukemia Effect After Allogeneic Stem Cell Transplantation ⬇️

Genomic loss of patient-specific HLA in acute myeloid leukemia relapse after well-matched unrelated donor HSCT.

Handling, processing and disposal of stem cell products in Europe: A survey by the cellular therapy and immunobiology working party of the European Society for Blood and Marrow Transplantation

Haploidentical HSCT: a 15-year experience at San Raffaele.

Hematopoietic SCT in Europe 2013: recent trends in the use of alternative donors showing more haploidentical donors but fewer cord blood transplants.

Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually.

Hematopoietic stem cell transplantation in its 60s: A platform for cellular therapies.

Human Herpesvirus 6 Infection Following Haploidentical Transplantation: Immune Recovery and Outcome.

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors.

Immune monitoring in allogeneic hematopoietic stem cell transplant recipients: a survey from the EBMT-CTIWP.

Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

Immunotherapy of human viral and malignant diseases with genetically modified T-cell clones.

Impact of drug development on the use of stem cell transplantation: a report by the European Society for Blood and Marrow Transplantation (EBMT).

Improving the safety of cell therapy with the TK-suicide gene

In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells

Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation.

Indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2019.

Inflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMD

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study.

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy.

Long term follow up of patients after allogeneic stem cell transplantation and transfusion of HSV-TK transduced T-cells.

Loss of mismatched HLA in leukemia after stem-cell transplantation.

Manufacturing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers Affiliated with the European Society for Blood and Marrow Transplantation

Missing HLA C group 1 ligand in patients with AML and MDS is associated with reduced risk of relapse and better survival after allogeneic stem cell transplantation with fludarabine and treosulfan reduced toxicity conditioning.

Modulation of GvHD by suicide-gene transduced donor T lymphocytes: clinical applications in mismatched transplantation.

Molecular modification of idiotypes from B-cell lymphomas for expression in mature dendritic cells as a strategy to induce tumor-reactive CD4+ and CD8+ T-cell responses.

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: dynamics and clinical implications.

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer.

Post-transplantation Cyclophosphamide and Sirolimus after Haploidentical Hematopoietic Stem Cell Transplantation Using a Treosulfan-based Myeloablative Conditioning and Peripheral Blood Stem Cells

Potential and limitations of HSV-TK-transduced donor peripheral blood lymphocytes after allo-BMT

Predicting the Clinical Outcome of Allogeneic Hematopoietic Stem Cell Transplantation: The Long and Winding Road toward Validated Immune Biomarkers.

Prevention and treatment of relapse after stem cell transplantation by cellular therapies

Proceedings From the Fourth Haploidentical Stem Cell Transplantation Symposium - HAPLO2016, San Diego, California, December 1, 2016.

Restoring Natural Killer Cell Immunity against Multiple Myeloma in the Era of New Drugs.

Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.

Safety of retroviral gene marking with a truncated NGF receptor

Secondary malignancies after high-dose chemotherapy in germ cell tumor patients: a 34-year retrospective study of the European Society for Blood and Marrow Transplantation (EBMT).

Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.

Site-specific integration and tailoring of cassette design for sustainable gene transfer.

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

T memory stem cells in health and disease.

T-cell suicide gene therapy prompts thymic renewal in adults after hematopoietic stem cell transplantation.

Targeted genome editing in human repopulating haematopoietic stem cells

Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation.

The hidden (and lazy) TCR

Therapeutic and diagnostic applications of minor histocompatibility antigen HA-1 and HA-2 disparities in allogeneic hematopoietic stem cell transplantation: a survey of different populations.

Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory.

Transcriptional enhancers induce insertional gene deregulation independently from the vector type and design.

Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes.