Lista de obras -

3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): cloning and characterization of a mouse liver HL cDNA and subchromosomal mapping of the human and mouse HL genes

artículo científico publicado en 1993

3-Hydroxy-3-methylglutaryldithio-CoA: utility of an alternative substrate in elucidation of a role for HMG-CoA lyase's cation activator

artículo científico publicado en 1993

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity.

artículo científico publicado en 2004

Acute sulfonylurea therapy at disease onset can cause permanent remission of KATP-induced diabetes.

artículo científico publicado en 2011

Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines ⬇️

artículo científico publicado el 1 de septiembre de 1992

Commentary

scientific article published on 01 December 2015

Contribution of systemic inflammation to permanence of KATP-induced neonatal diabetes in mice

scientific article published on 18 September 2018

Deficiencies in Scientific Evidence for Medical Management of Gender Dysphoria

scientific article published on 20 September 2019

Delayed hepatocellular mitotic progression and impaired liver regeneration in early growth response-1-deficient mice.

artículo científico publicado en 2004

Development of GLUT4-selective antagonists for multiple myeloma therapy.

artículo científico publicado en 2017

Direct comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal

artículo científico publicado en 2005

Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice.

artículo científico publicado en 2004

Evaluating the Efficacy of GLUT Inhibitors Using a Seahorse Extracellular Flux Analyzer.

artículo científico publicado en 2018

Expression, purification, and functional characterization of the insulin-responsive facilitative glucose transporter GLUT4.

artículo científico publicado en 2015

GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle ⬇️

artículo científico publicado el 8 de junio de 2012

GS-8374, a novel HIV protease inhibitor, does not alter glucose homeostasis in cultured adipocytes or in a healthy-rodent model system.

artículo científico publicado en 2011

HIV Protease Inhibitors Act as Competitive Inhibitors of the Cytoplasmic Glucose Binding Site of GLUTs with Differing Affinities for GLUT1 and GLUT4 ⬇️

artículo científico publicado el 23 de septiembre de 2011

HIV and endocrine disorders.

artículo científico publicado en 2014

HIV protease inhibitors acutely impair glucose-stimulated insulin release.

artículo científico publicado en 2003

HIV protease inhibitors and insulin resistance: lessons from in-vitro, rodent and healthy human volunteer models

artículo científico publicado en 2008

Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering

scientific article published on 09 May 2019

In Silico Modeling-based Identification of Glucose Transporter 4 (GLUT4)-selective Inhibitors for Cancer Therapy.

artículo científico publicado en 2015

Indinavir induces acute and reversible peripheral insulin resistance in rats.

artículo científico publicado en 2002

Investigating the cellular targets of HIV protease inhibitors: implications for metabolic disorders and improvements in drug therapy.

artículo científico publicado en 2002

Isoform-selective inhibition of facilitative glucose transporters: elucidation of the molecular mechanism of HIV protease inhibitor binding.

artículo científico publicado en 2014

Letter to the Editor: "Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline"

scientific article published on 01 March 2019

Liver regeneration is impaired in lipodystrophic fatty liver dystrophy mice.

artículo científico publicado en 2010

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis.

artículo científico publicado en 2017

Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids

artículo científico publicado en 2016

Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia.

artículo científico publicado en 2018

Molecular Mechanisms for Altered Glucose Homeostasis in HIV Infection

artículo científico publicado en 2006

Molecular mechanisms for insulin resistance in treated HIV-infection ⬇️

artículo científico publicado el 1 de junio de 2011

Rosiglitazone inhibits mouse liver regeneration

artículo científico publicado en 2006

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy.

artículo científico publicado en 2016

Saxagliptin Improves Glucose Tolerance but not Survival in a Murine Model of Dilated Cardiomyopathy

artículo científico publicado en 2012

Structural analysis of the GLUT1 facilitative glucose transporter ⬇️

artículo científico publicado el 1 de julio de 2001

TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose

scientific article published on 06 August 2018

The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir.

artículo científico publicado en 2015

The mechanism of insulin resistance caused by HIV protease inhibitor therapy.

artículo científico publicado en 2000

The role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implications

artículo científico publicado en 2009

Tipranavir without ritonavir does not acutely induce peripheral insulin resistance in a rodent model

scientific article published on 01 December 2006

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

artículo científico publicado en 2016

Lista de obras de

3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): cloning and characterization of a mouse liver HL cDNA and subchromosomal mapping of the human and mouse HL genes

3-Hydroxy-3-methylglutaryldithio-CoA: utility of an alternative substrate in elucidation of a role for HMG-CoA lyase's cation activator

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity.

Acute sulfonylurea therapy at disease onset can cause permanent remission of KATP-induced diabetes.

Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines ⬇️

Commentary

Contribution of systemic inflammation to permanence of KATP-induced neonatal diabetes in mice

Deficiencies in Scientific Evidence for Medical Management of Gender Dysphoria

Delayed hepatocellular mitotic progression and impaired liver regeneration in early growth response-1-deficient mice.

Development of GLUT4-selective antagonists for multiple myeloma therapy.

Direct comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal

Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice.

Evaluating the Efficacy of GLUT Inhibitors Using a Seahorse Extracellular Flux Analyzer.

Expression, purification, and functional characterization of the insulin-responsive facilitative glucose transporter GLUT4.

GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle ⬇️

GS-8374, a novel HIV protease inhibitor, does not alter glucose homeostasis in cultured adipocytes or in a healthy-rodent model system.

HIV Protease Inhibitors Act as Competitive Inhibitors of the Cytoplasmic Glucose Binding Site of GLUTs with Differing Affinities for GLUT1 and GLUT4 ⬇️

HIV and endocrine disorders.

HIV protease inhibitors acutely impair glucose-stimulated insulin release.

HIV protease inhibitors and insulin resistance: lessons from in-vitro, rodent and healthy human volunteer models

Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering

In Silico Modeling-based Identification of Glucose Transporter 4 (GLUT4)-selective Inhibitors for Cancer Therapy.

Indinavir induces acute and reversible peripheral insulin resistance in rats.

Investigating the cellular targets of HIV protease inhibitors: implications for metabolic disorders and improvements in drug therapy.

Isoform-selective inhibition of facilitative glucose transporters: elucidation of the molecular mechanism of HIV protease inhibitor binding.

Letter to the Editor: "Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline"

Liver regeneration is impaired in lipodystrophic fatty liver dystrophy mice.

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis.

Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids

Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia.

Molecular Mechanisms for Altered Glucose Homeostasis in HIV Infection

Molecular mechanisms for insulin resistance in treated HIV-infection ⬇️

Rosiglitazone inhibits mouse liver regeneration

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy.

Saxagliptin Improves Glucose Tolerance but not Survival in a Murine Model of Dilated Cardiomyopathy

Structural analysis of the GLUT1 facilitative glucose transporter ⬇️

TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose

The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir.

The mechanism of insulin resistance caused by HIV protease inhibitor therapy.

The role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implications

Tipranavir without ritonavir does not acutely induce peripheral insulin resistance in a rodent model

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis