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A fluorescent analogue of tauroursodeoxycholic acid reduces ER stress and is cytoprotective

artículo científico publicado en 2016

A high-content analysis toolbox permits dissection of diverse signaling pathways for T lymphocyte polarization.

artículo científico publicado en 2010

Advances in bile acid medicinal chemistry.

artículo científico

Advances in siRNA delivery to T-cells: potential clinical applications for inflammatory disease, cancer and infection

artículo científico

An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-kappaB activation and cytokine levels.

artículo científico publicado en 2010

Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells.

artículo científico publicado en 2011

Aromatic aldehydes as substrates for yeast and yeast alcohol dehydrogenase

scientific article published on 01 January 1989

Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).

artículo científico publicado en 2010

Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells.

artículo científico publicado en 2010

Biotransformation of benzaldehyde by Saccharomyces cerevisiae: characterization of the fermentation and toxicity effects of substrates and products.

artículo científico publicado en 1989

CD44 cross-linking induces protein kinase C-regulated migration of human T lymphocytes.

artículo científico publicado en 2005

Candidate Gene Knockdown in Celiac Disease

article

Cellular proliferation and activation of NF kappa B are induced by autocrine production of tumor necrosis factor alpha in the human T lymphoma line HuT 78.

artículo científico publicado en 1995

Cross-linking of LFA-1 induces secretion of macrophage inflammatory protein (MIP)-1α and MIP-1β with consequent directed migration of activated lymphocytes

artículo científico publicado en 2000

Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells.

artículo científico publicado en 2001

Deoxycholic acid impairs glycosylation and fucosylation processes in esophageal epithelial cells.

artículo científico publicado en 2012

Development and characterization of a protein kinase C beta-isozyme-deficient T-cell line

artículo científico publicado el 27 de abril de 1992

Engagement of CD44 modulates cyclooxygenase induction, VEGF generation, and proliferation in human vascular endothelial cells.

artículo científico publicado en 2005

Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion.

artículo científico publicado en 2015

Hepatitis C virus--T-cell responses and viral escape mutations.

artículo científico publicado en 2011

L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes

artículo científico publicado en 2012

Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.

artículo científico publicado en 2007

Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: a common pathway for epithelial cell injury?

artículo científico publicado en 2005

New fluorescent bile acids: synthesis, chemical characterization, and disastereoselective uptake by Caco-2 cells of 3-deoxy 3-NBD-amino deoxycholic and ursodeoxycholic acid

artículo científico publicado en 2012

New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid.

artículo científico publicado en 2013

Phosphorylation of Rab5a protein by protein kinase Cϵ is crucial for T-cell migration.

artículo científico publicado en 2014

Protein kinase C and T cell function

artículo científico publicado el 11 de septiembre de 1997

Protein kinase C delta is a substrate of tissue transglutaminase and a novel autoantigen in coeliac disease

artículo científico publicado el 26 de enero de 2013

Protein kinase C: a regulator of cytoskeleton remodelling and T-cell migration.

artículo científico publicado en 2014

RACK1 to the future--a historical perspective

artículo científico publicado en 2013

RNAi Screening with Self-Delivering, Synthetic siRNAs for Identification of Genes That Regulate Primary Human T Cell Migration.

artículo científico publicado en 2015

Regulation of Protein Kinase C function by phosphorylation on conserved and non-conserved sites.

artículo científico publicado en 2010

Regulation of non-classical protein kinase C isoenzymes in a human T cell line.

artículo científico publicado en 1995

Roles for RACK1 in cancer cell migration and invasion

artículo científico publicado en 2017

STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL.

artículo científico publicado en 2010

Shear stress induces internalization of E-cadherin and invasiveness in metastatic oesophageal cancer cells by a Src-dependent pathway.

artículo científico publicado en 2009

Statistical methods for analysis of high-throughput RNA interference screens

artículo científico publicado en 2009

Stimulus-induced phosphorylation of PKC theta at the C-terminal hydrophobic-motif in human T lymphocytes.

artículo científico publicado en 2005

Subcellular localization and translocation of protein kinase C isoforms zeta and epsilon in human peripheral blood lymphocytes

artículo científico publicado en 1997

Suppressor of cytokine signalling (SOCS) 1 and 3 enhance cell adhesion and inhibit migration towards the chemokine eotaxin/CCL11

artículo científico publicado el 8 de octubre de 2010

TNF-mediated cytotoxicity of L929 cells: role of staurosporine in enhancement of cytotoxicity and translocation of protein kinase C isozymes.

artículo científico publicado en 1997

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility

artículo científico publicado el 29 de marzo de 2011

The effects of conjugated linoleic acid supplementation on immune function in healthy volunteers.

artículo científico publicado en 2005

The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cadherin expression in colon cancer cells.

artículo científico publicado en 2006

Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism.

artículo científico publicado en 2016

Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators.

artículo científico publicado en 2010