Lista de obras -

5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.

artículo científico publicado en 2004

A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma ⬇️

artículo científico publicado el 12 de marzo de 2013

A morphological method for ammonia detection in liver

artículo científico publicado en 2017

Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steatohepatitis ⬇️

artículo científico publicado el 1 de noviembre de 2010

Activation of a novel c-Myc-miR27-prohibitin 1 circuitry in cholestatic liver injury inhibits glutathione synthesis in mice.

artículo científico publicado en 2014

Alcohol, DNA methylation, and cancer

artículo científico publicado en 2013

An update on the use of benzoate, phenylacetate and phenylbutyrate ammonia scavengers for interrogating and modifying liver nitrogen metabolism and its implications in urea cycle disorders and liver disease

artículo científico publicado en 2016

Assignment of a single disulfide bridge in rat liver methionine adenosyltransferase

artículo científico publicado en 2000

Atorvastatin provides a new lipidome improving early regeneration after partial hepatectomy in osteopontin deficient mice

artículo científico publicado en 2018

Biphasic adaptative responses in VLDL metabolism and lipoprotein homeostasis during Gram-negative endotoxemia

artículo científico publicado en 2010

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart

artículo científico publicado en 2021

Causes of hOCT1-Dependent Cholangiocarcinoma Resistance to Sorafenib and Sensitization by Tumor-Selective Gene Therapy

article

Corrigendum: Hepatic p63 regulates steatosis via IKKβ/ER stress.

artículo científico publicado en 2017

Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

artículo científico publicado en 2018

Crystallization and preliminary crystallographic analysis of merohedrally twinned crystals of MJ0729, a CBS-domain protein from Methanococcus jannaschii.

artículo científico publicado en 2008

Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators ⬇️

scientific article published on 06 March 2019

Deregulated neddylation in liver fibrosis

artículo científico publicado en 2016

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

artículo científico publicado en 2015

Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis

artículo científico publicado en 2020

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

scientific article published on 11 February 2019

Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation.

artículo científico publicado en 2009

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury.

artículo científico publicado en 2005

GARBAN: genomic analysis and rapid biological annotation of cDNA microarray and proteomic data.

artículo científico publicado en 2003

GRK2-Dependent HuR Phosphorylation Regulates HIF1α Activation under Hypoxia or Adrenergic Stress

artículo científico publicado en 2020

Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance

artículo científico publicado en 2014

Hepatic p63 regulates steatosis via IKKβ/ER stress

artículo científico publicado en 2017

Hepatocellular Carcinoma: Updates in Pathogenesis, Detection and Treatment

scientific article published on 23 September 2020

Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.

artículo científico publicado en 2012

High-frequency ultrasound imaging for longitudinal evaluation of non-alcoholic fatty liver disease progression in mice.

artículo científico publicado en 2011

Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1

artículo científico publicado en 2015

HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.

artículo científico publicado en 2019

HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis

scientific journal article

Human antigen R contributes to hepatic stellate cell activation and liver fibrosis

artículo científico publicado en 2012

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

artículo científico publicado en 2017

Identification of a gene-pathway associated with non-alcoholic steatohepatitis

artículo científico publicado en 2006

Impaired liver regeneration in mice lacking glycine N-methyltransferase.

artículo científico publicado en 2009

Inhibiting expression of specific genes in mammalian cells with 5' end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA.

artículo científico publicado en 2003

Integrative genomic signatures of hepatocellular carcinoma derived from nonalcoholic Fatty liver disease.

artículo científico publicado en 2015

Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans

scientific article published on 24 September 2018

Liver Angiopoietin-2 is a key predictor of de novo or recurrent hepatocellular cancer after HCV direct-acting antivirals

artículo científico publicado en 2018

Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice ⬇️

artículo científico publicado el 1 de octubre de 2010

Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.

artículo científico publicado en 2017

Metabolomics Discloses Potential Biomarkers for the Noninvasive Diagnosis of Idiopathic Portal Hypertension

artículo científico publicado en 2013

Metabolomics as a diagnostic tool for idiopathic non-cirrhotic portal hypertension

artículo científico publicado en 2015

Metabolomics discloses potential biomarkers to predict the acute HVPG response to propranolol in patients with cirrhosis

scientific article published on 10 February 2019

Metabolomic‐based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts.

artículo científico publicado en 2018

Methionine Adenosyltransferase α1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression

artículo científico publicado en 2019

Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.

artículo científico publicado en 2013

Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.

artículo científico publicado en 2014

Methionine adenosyltransferase and S-adenosylmethionine in alcoholic liver disease.

artículo científico publicado en 2006

Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis

artículo científico publicado en 2015

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

artículo científico publicado en 2018

Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study.

artículo científico

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.

artículo científico publicado en 2012

Multi-Omics Integration Highlights the Role of Ubiquitination in CCl<sub>4</sub>-Induced Liver Fibrosis

scientific article published on 27 November 2020

Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation

artículo científico publicado en 2012

NEDDylation in liver cancer: The regulation of the RNA binding protein Hu antigen R.

artículo científico

Neddylation, a novel paradigm in liver cancer

scientific article published on 30 June 2018

Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study.

artículo científico

Non-alcoholic steatohepatitis and animal models: understanding the human disease.

artículo científico publicado en 2008

Nonalcoholic steatohepatitis, animal models, and biomarkers: what is new?

scientific article published on 01 January 2010

Novel function and intracellular localization of methionine adenosyltransferase 2beta splicing variants

artículo científico publicado en 2010

Nutraceutical Properties of Polyphenols against Liver Diseases

artículo científico publicado en 2020

Obesity-dependent metabolic signatures associated with nonalcoholic fatty liver disease progression

artículo científico publicado en 2012

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

artículo científico publicado en 2020

Plasticity of adult hepatocytes and readjustment of cell fate: a novel dogma in liver disease

artículo científico publicado en 2019

Post-translational modifiers of liver kinase B1/serine/threonine kinase 11 in hepatocellular carcinoma

artículo científico publicado en 2019

Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells

artículo científico publicado en 2016

Purification, crystallization and preliminary X-ray diffraction analysis of the CBS-domain pair from the Methanococcus jannaschii protein MJ0100

artículo científico publicado en 2008

Regulation of oxidative stress by methylation-controlled J protein controls macrophage responses to inflammatory insults

artículo científico publicado en 2014

Regulation of rat liver S-adenosylmethionine synthetase during septic shock: role of nitric oxide

artículo científico publicado en 1997

Repression of the nuclear receptor small heterodimer partner by steatotic drugs and in advanced nonalcoholic fatty liver disease

artículo científico publicado en 2015

Role of Aramchol in steatohepatitis and fibrosis in mice

artículo científico publicado en 2017

Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

artículo científico publicado en 1996

S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease.

artículo científico publicado en 2014

S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.

artículo científico publicado en 2010

S-adenosyl-L-methionine modifies antioxidant-enzymes, glutathione-biosynthesis and methionine adenosyltransferases-1/2 in hepatitis C virus-expressing cells

artículo científico publicado en 2016

S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

artículo científico publicado en 2002

S-adenosylmethionine levels regulate the schwann cell DNA methylome.

artículo científico publicado en 2014

S-adenosylmethionine metabolism and liver disease.

artículo científico

S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase

scientific article published on 01 July 2006

SAMe and HuR in liver physiology: usefulness of stem cells in hepatic differentiation research

artículo científico publicado en 2012

SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.

artículo científico publicado en 2014

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer

artículo científico publicado en 2019

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

artículo científico publicado en 2018

Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.

artículo científico publicado en 2008

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves.

artículo científico publicado en 2015

Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma and primary sclerosing cholangitis

artículo científico publicado en 2019

Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation

artículo científico publicado en 2020

Sirtuin 1 regulation of developmental genes during differentiation of stem cells.

artículo científico publicado en 2010

Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.

artículo científico

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer

artículo científico publicado en 2015

Stratification and therapeutic potential of PML in metastatic breast cancer

artículo científico publicado en 2016

Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.

artículo científico publicado en 2016

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

artículo científico publicado en 2015

Systems biology for hepatologists

artículo científico publicado en 2014

TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency

artículo científico publicado en 2014

Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF-β-Dependent Fibrogenesis

artículo científico publicado en 2014

The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity

artículo científico publicado en 2019

The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets.

artículo científico publicado en 2014

The Need for Biomarkers in Diagnosis and Prognosis of Drug-Induced Liver Disease: Does Metabolomics Have Any Role?

artículo científico publicado en 2015

The RNA-binding protein human antigen R controls global changes in gene expression during Schwann cell development.

artículo científico publicado en 2012

The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant

artículo científico publicado en 2017

The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.

artículo científico publicado en 2017

The promyelocytic leukemia protein is upregulated in conditions of obesity and liver steatosis

artículo científico publicado en 2015

The role of stem cells/progenitor cells in liver carcinogenesis in glycine N-methyltransferase deficient mice.

artículo científico publicado en 2010

Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin.

artículo científico publicado en 2014

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.

artículo científico publicado en 2017

miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease

scientific article published on 16 August 2019

Lista de obras de

5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.

A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma ⬇️

A morphological method for ammonia detection in liver

Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steatohepatitis ⬇️

Activation of a novel c-Myc-miR27-prohibitin 1 circuitry in cholestatic liver injury inhibits glutathione synthesis in mice.

Alcohol, DNA methylation, and cancer

An update on the use of benzoate, phenylacetate and phenylbutyrate ammonia scavengers for interrogating and modifying liver nitrogen metabolism and its implications in urea cycle disorders and liver disease

Assignment of a single disulfide bridge in rat liver methionine adenosyltransferase

Atorvastatin provides a new lipidome improving early regeneration after partial hepatectomy in osteopontin deficient mice

Biphasic adaptative responses in VLDL metabolism and lipoprotein homeostasis during Gram-negative endotoxemia

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart

Causes of hOCT1-Dependent Cholangiocarcinoma Resistance to Sorafenib and Sensitization by Tumor-Selective Gene Therapy

Corrigendum: Hepatic p63 regulates steatosis via IKKβ/ER stress.

Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

Crystallization and preliminary crystallographic analysis of merohedrally twinned crystals of MJ0729, a CBS-domain protein from Methanococcus jannaschii.

Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators ⬇️

Deregulated neddylation in liver fibrosis

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation.

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury.

GARBAN: genomic analysis and rapid biological annotation of cDNA microarray and proteomic data.

GRK2-Dependent HuR Phosphorylation Regulates HIF1α Activation under Hypoxia or Adrenergic Stress

Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance

Hepatic p63 regulates steatosis via IKKβ/ER stress

Hepatocellular Carcinoma: Updates in Pathogenesis, Detection and Treatment

Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.

High-frequency ultrasound imaging for longitudinal evaluation of non-alcoholic fatty liver disease progression in mice.

Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1

HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.

HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis

Human antigen R contributes to hepatic stellate cell activation and liver fibrosis

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

Identification of a gene-pathway associated with non-alcoholic steatohepatitis

Impaired liver regeneration in mice lacking glycine N-methyltransferase.

Inhibiting expression of specific genes in mammalian cells with 5' end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA.

Integrative genomic signatures of hepatocellular carcinoma derived from nonalcoholic Fatty liver disease.

Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans

Liver Angiopoietin-2 is a key predictor of de novo or recurrent hepatocellular cancer after HCV direct-acting antivirals

Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice ⬇️

Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.

Metabolomics Discloses Potential Biomarkers for the Noninvasive Diagnosis of Idiopathic Portal Hypertension

Metabolomics as a diagnostic tool for idiopathic non-cirrhotic portal hypertension

Metabolomics discloses potential biomarkers to predict the acute HVPG response to propranolol in patients with cirrhosis

Metabolomic‐based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts.

Methionine Adenosyltransferase α1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression

Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.

Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.

Methionine adenosyltransferase and S-adenosylmethionine in alcoholic liver disease.

Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study.

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.

Multi-Omics Integration Highlights the Role of Ubiquitination in CCl<sub>4</sub>-Induced Liver Fibrosis

Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation

NEDDylation in liver cancer: The regulation of the RNA binding protein Hu antigen R.

Neddylation, a novel paradigm in liver cancer

Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study.

Non-alcoholic steatohepatitis and animal models: understanding the human disease.

Nonalcoholic steatohepatitis, animal models, and biomarkers: what is new?

Novel function and intracellular localization of methionine adenosyltransferase 2beta splicing variants

Nutraceutical Properties of Polyphenols against Liver Diseases

Obesity-dependent metabolic signatures associated with nonalcoholic fatty liver disease progression

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

Plasticity of adult hepatocytes and readjustment of cell fate: a novel dogma in liver disease

Post-translational modifiers of liver kinase B1/serine/threonine kinase 11 in hepatocellular carcinoma

Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells

Purification, crystallization and preliminary X-ray diffraction analysis of the CBS-domain pair from the Methanococcus jannaschii protein MJ0100

Regulation of oxidative stress by methylation-controlled J protein controls macrophage responses to inflammatory insults

Regulation of rat liver S-adenosylmethionine synthetase during septic shock: role of nitric oxide

Repression of the nuclear receptor small heterodimer partner by steatotic drugs and in advanced nonalcoholic fatty liver disease

Role of Aramchol in steatohepatitis and fibrosis in mice

Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease.

S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.

S-adenosyl-L-methionine modifies antioxidant-enzymes, glutathione-biosynthesis and methionine adenosyltransferases-1/2 in hepatitis C virus-expressing cells

S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

S-adenosylmethionine levels regulate the schwann cell DNA methylome.