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Acenaphthenequinone thiosemicarbazone and its transition metal complexes: synthesis, structure, and biological activity

scientific article published on 01 April 1997

Air purification and indoor biologic pollutants

artículo científico publicado en 2000

Arsenic trioxide (ATO) and MEK1 inhibition synergize to induce apoptosis in acute promyelocytic leukemia cells.

artículo científico publicado en 2005

Arsenic trioxide in hematological malignancies: the new discovery of an ancient drug.

artículo científico publicado en 2006

Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.

artículo científico publicado en 2008

Diorganotin(IV) complexes of pyridoxal thiosemicarbazone: Synthesis, spectroscopic properties and biological activity

artículo científico publicado el 1 de marzo de 1998

Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts

artículo científico publicado en 2003

Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis.

artículo científico publicado en 2004

Early Proinflammatory Activation of Renal Tubular Cells by Normal and Pathologic IgG

artículo científico publicado en 2005

Emerging MEK inhibitors.

artículo científico publicado en 2010

Emerging Raf inhibitors.

artículo científico publicado en 2009

Human myeloma cells express the bone regulating gene Runx2/Cbfa1 and produce osteopontin that is involved in angiogenesis in multiple myeloma patients

artículo científico publicado en 2005

MEK-ERK pathway is expressed but not activated in high proliferating, self-renewing cord blood hematopoietic progenitors

scientific article published on 01 January 2002

MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosis.

artículo científico publicado en 2006

Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis

artículo científico publicado en 2003

Synthesis, characterisation, X-ray structure and biological activity of three new 5-formyluracil thiosemicarbazone complexes.

artículo científico publicado en 2001

Synthesis, spectroscopic characterization and biological properties of new natural aldehydes thiosemicarbazones.

artículo científico publicado en 2000

Synthesis, structure, and spectroscopic properties of acetato(dimethyl)(pyridine-2-carbaldehydethiosemicarbazonato)tin(IV) acetic acid solvate, [SnMe2(PyTSC)(OAc)].HOAc. Comparison of its biological activity with that of some structurally related di

artículo científico publicado en 1996

Synthesis, structure, spectroscopic properties and biological activity of mixed diorganotin(IV) complexes containing pyridine-2-carbaldehyde thiosemicarbazonato and diphenyldithiophosphinato ligands

artículo científico publicado en 1999

Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways.

artículo científico publicado en 2008

Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.

artículo científico publicado en 2008

The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angio

artículo científico publicado en 2007

The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting.

artículo científico publicado en 2009

Transition-metal complexes of isatin-beta-thiosemicarbazone. X-ray crystal structure of two nickel complexes

artículo científico publicado en 1999

Treatment with arsenic trioxide (ATO) and MEK1 inhibitor activates the p73-p53AIP1 apoptotic pathway in leukemia cells.

artículo científico publicado en 2004

p73 and p53 pathway in human breast cancers

scientific article published on 01 April 2007