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A Strategy for Testing the Suitability of Cysteine Replacements in Dihydrofolate Reductase from Escherichia coli1

artículo científico publicado el 1 de marzo de 1995

An engineered human follistatin variant: insights into the pharmacokinetic and pharmocodynamic relationships of a novel molecule with broad therapeutic potential.

artículo científico publicado en 2012

Binding of the catabolite repressor protein CcpA to its DNA target is regulated by phosphorylation of its corepressor HPr

scientific article published on 01 October 1997

Development of a high-throughput solubility screening assay for use in antibody discovery

scientific article published on 26 March 2019

Development of nonpolar surfaces in the folding of Escherichia coli dihydrofolate reductase detected by 1-anilinonaphthalene-8-sulfonate binding

artículo científico publicado en 1994

Development of tibulizumab, a tetravalent bispecific antibody targeting BAFF and IL-17A for the treatment of autoimmune disease

scientific article published on 10 June 2019

Distinct functions of activated protein C differentially attenuate acute kidney injury.

artículo científico publicado en 2008

Engineering the proteolytic specificity of activated protein C improves its pharmacological properties

artículo científico publicado en 2003

LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection

artículo científico publicado en 2020

Local and global dynamics during the folding of Escherichia coli dihydrofolate reductase by time-resolved fluorescence spectroscopy

scientific article published on 01 February 1995

Multiple antibody specificities (gp41, V1V2, and V3) elicited in the phase II multiclade (A, B, C) HIV-1 DNA prime, rAd5 boost vaccine trial

artículo científico publicado en 2012

Myostatin Neutralization Results in Preservation of Muscle Mass and Strength in Preclinical Models of Tumor-Induced Muscle Wasting

artículo científico publicado en 2015

Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis.

artículo científico publicado en 1997

Probing the folding mechanism of a leucine zipper peptide by stopped-flow circular dichroism spectroscopy

scientific article published on 01 October 1995

RAMPED-UP NMR: multiplexed NMR-based screening for drug discovery.

artículo científico publicado en 2003

Solvent exchange rates of side-chain amide protons in proteins.

artículo científico publicado en 1998

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

artículo científico publicado en 2021