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Alternative splicing variants of proinsulin mRNA and the effects of excess proinsulin on cardiac morphogenesis.

artículo científico publicado en 2013

Autocrine/paracrine role of insulin-related growth factors in neurogenesis: local expression and effects on cell proliferation and differentiation in retina

artículo científico publicado en 1995

Balance of pro-apoptotic transforming growth factor-beta and anti-apoptotic insulin effects in the control of cell death in the postnatal mouse retina.

artículo científico publicado en 2005

Developmental regulation of a proinsulin messenger RNA generated by intron retention.

artículo científico publicado en 2005

Evolution of the insulin receptor family and receptor isoform expression in vertebrates.

artículo científico publicado en 2008

Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation

article

Insulin and insulin-like growth factor system components gene expression in the chicken retina from early neurogenesis until late development and their effect on neuroepithelial cells.

artículo científico publicado en 1994

Intravitreal Injection of Proinsulin-Loaded Microspheres Delays Photoreceptor Cell Death and Vision Loss in the rd10 Mouse Model of Retinitis Pigmentosa

artículo científico publicado en 2016

Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa

artículo científico publicado en 2018

Non-neural tyrosine hydroxylase, via modulation of endocrine pancreatic precursors, is required for normal development of beta cells in the mouse pancreas

artículo científico publicado en 2014

Premature aging in behavior and immune functions in tyrosine hydroxylase haploinsufficient female mice. A longitudinal study

artículo científico publicado en 2018

Premature immunosenescence in catecholamines syntesis deficient mice. Effect of social environment

artículo científico publicado en 2016

Proinsulin in development: New roles for an ancient prohormone.

artículo científico publicado en 2006

Proinsulin protects against age-related cognitive loss through anti-inflammatory convergent pathways.

artículo científico publicado en 2017

Small molecules targeting glycogen synthase kinase 3 as potential drug candidates for the treatment of retinitis pigmentosa.

artículo científico publicado en 2017

The Prohormone Proinsulin as a Neuroprotective Factor: Past History and Future Prospects

scientific article published on 26 November 2018

The regulated expression of chimeric tyrosine hydroxylase-insulin transcripts during early development.

artículo científico publicado en 2006

The regulation of IGF-I receptor gene expression.

artículo científico publicado en 1995

Tyrosine hydroxylase haploinsufficiency prevents age-associated arterial pressure elevation and increases half-life in mice.

artículo científico publicado en 2016

Tyrosine hydroxylase is expressed during early heart development and is required for cardiac chamber formation.

artículo científico publicado en 2010

Unprocessed proinsulin promotes cell survival during neurulation in the chick embryo.

artículo científico publicado en 2002

Upstream AUGs in embryonic proinsulin mRNA control its low translation level.

artículo científico

p75NTR antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa

artículo científico publicado en 2017