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Amyloid-induced β-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment

artículo científico publicado en 2017

BACE2 suppression promotes β-cell survival and function in a model of type 2 diabetes induced by human islet amyloid polypeptide overexpression.

artículo científico publicado en 2017

Chaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpression

artículo científico publicado en 2014

Circulating miR-192 and miR-193b are markers of prediabetes and are modulated by an exercise intervention

artículo científico publicado en 2014

Distinct roles of HNF1beta, HNF1alpha, and HNF4alpha in regulating pancreas development, beta-cell function and growth.

artículo científico publicado en 2007

Effects of Oxidative Stress on Phospholipid Signaling in Rat Cultured Astrocytes and Brain Slices

artículo científico publicado en 2000

Gene expression dynamics after murine pancreatitis unveils novel roles for Hnf1α in acinar cell homeostasis.

artículo científico publicado en 2011

Glucose regulation of a cell cycle gene module is selectively lost in mouse pancreatic islets during ageing

artículo científico publicado el 18 de mayo de 2013

Group I metabotropic glutamate receptors mediate phospholipase D stimulation in rat cultured astrocytes.

artículo científico publicado en 1999

Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver.

artículo científico publicado en 2009

Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas

scientific journal article

Inhibition of BACE2 counteracts hIAPP-induced insulin secretory defects in pancreatic β-cells

artículo científico publicado en 2014

Intracellular Ca2+ Stores Regulate Muscarinic Receptor Stimulation of Phospholipase C in Cerebellar Granule Cells

scientific article published on 01 February 2000

Involvement of ET(A) and ET(B) receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes.

artículo científico publicado en 1998

Islet amyloid polypeptide exerts a novel autocrine action in β-cell signaling and proliferation.

artículo científico publicado en 2015

Late-stage differentiation of embryonic pancreatic β-cells requires Jarid2

artículo científico publicado en 2017

Maternal Exposure to Bisphenol-A During Pregnancy Increases Pancreatic β-Cell Growth During Early Life in Male Mice Offspring

artículo científico publicado en 2016

Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

artículo científico publicado en 2003

Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.

artículo científico publicado en 2017

Persistent activation of Rac1 in squamous carcinomas of the head and neck: evidence for an EGFR/Vav2 signaling axis involved in cell invasion.

artículo científico publicado en 2007

Potent activation of RhoA by Galpha q and Gq-coupled receptors.

artículo científico publicado en 2002

Protein disulfide isomerase ameliorates β-cell dysfunction in pancreatic islets overexpressing human islet amyloid polypeptide

artículo científico publicado en 2015

Putting pancreatic cell plasticity to the test.

artículo científico publicado en 2007

Retinoic acid-induced differentiation into astrocytes and glutamatergic neurons is associated with expression of functional and activable phospholipase D.

artículo científico publicado en 2004

Stress-Induced MicroRNA-708 Impairs β-Cell Function and Growth.

artículo científico publicado en 2017

Thrombin protease-activated receptor-1 signals through Gq- and G13-initiated MAPK cascades regulating c-Jun expression to induce cell transformation.

artículo científico publicado en 2003

Thyroid hormones promote endocrine differentiation at expenses of exocrine tissue

artículo científico publicado en 2014

Transcriptional networks controlling pancreatic development and beta cell function.

artículo científico publicado en 2004

Two phosphatidylethanol classes separated by thin layer chromatography are produced by phospholipase D in rat brain hippocampal slices.

artículo científico publicado en 1996