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A Strategy to Find Suitable Reference Genes for miRNA Quantitative PCR Analysis and Its Application to Cervical Specimens.

artículo científico publicado en 2017

A protocol for urine collection and storage prior to DNA methylation analysis

artículo científico publicado en 2018

A role for EZH2 in silencing of IFN-gamma inducible MHC2TA transcription in uveal melanoma.

artículo científico publicado en 2007

Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence.

artículo científico publicado en 2016

Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide

artículo científico publicado en 2010

Age-dependence of human papillomavirus DNA presence in oral squamous cell carcinomas

artículo científico publicado en 1996

Alterations in AP-1 and AP-1 regulatory genes during HPV-induced carcinogenesis.

artículo científico publicado en 2008

Altered microRNA expression associated with chromosomal changes contributes to cervical carcinogenesis

artículo científico publicado en 2012

Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation

artículo científico publicado en 2010

Analysis of p53 status in tonsillar carcinomas associated with human papillomavirus

artículo científico publicado en 1994

Assessment of TGF-beta1-mediated growth inhibition of HPV-16- and HPV-18-transfected foreskin keratinocytes during and following immortalization.

artículo científico publicado en 2003

Association Between Type-specific HPV Infections and hTERT DNA Methylation in Patients with Invasive Cervical Cancer.

artículo científico publicado en 2016

Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC.

artículo científico publicado en 2008

Bladder cancer detection in urine using DNA methylation markers: a technical and prospective preclinical validation

artículo científico publicado en 2022

CADM1 and MAL promoter methylation levels in hrHPV-positive cervical scrapes increase proportional to degree and duration of underlying cervical disease.

artículo científico publicado en 2013

CADM1, MAL and miR124-2 methylation analysis in cervical scrapes to detect cervical and endometrial cancer.

artículo científico publicado en 2014

CGH arrays compared for DNA isolated from formalin-fixed, paraffin-embedded material

artículo científico

Cancer risk stratification of anal intraepithelial neoplasia in HIV-positive men by validated methylation markers associated with progression to cancer

artículo científico publicado en 2020

Cervical cancer detection by DNA methylation analysis in urine

Cervical cancer risk in HPV-positive women after a negative FAM19A4/mir124-2 methylation test: A post hoc analysis in the POBASCAM trial with 14 year follow-up

artículo científico publicado en 2018

Chromosomal gains and losses in human papillomavirus-associated neoplasia of the lower genital tract - a systematic review and meta-analysis.

artículo científico publicado en 2013

Chromosomal profiles of high-grade cervical intraepithelial neoplasia relate to duration of preceding high-risk human papillomavirus infection

artículo científico publicado en 2011

Chromosomal signatures of a subset of high-grade premalignant cervical lesions closely resemble invasive carcinomas.

artículo científico publicado en 2009

Circulating Tumor DNA Analysis: Clinical Implications for Colorectal Cancer Patients. A Systematic Review

artículo científico publicado en 2019

Clinical implications of (epi)genetic changes in HPV-induced cervical precancerous lesions.

artículo científico publicado en 2014

Clinical relevance of human papillomavirus testing in cytopathology.

artículo científico publicado en 2005

Clonal selection for transcriptionally active viral oncogenes during progression to cancer.

artículo científico publicado en 2004

Combined CADM1 and MAL promoter methylation analysis to detect (pre-)malignant cervical lesions in high-risk HPV-positive women.

artículo científico publicado en 2011

Combined CADM1/MAL methylation and cytology testing for colposcopy triage of high-risk HPV-positive women.

artículo científico publicado en 2014

Combined promoter methylation analysis of CADM1 and MAL: an objective triage tool for high-risk human papillomavirus DNA-positive women

artículo científico publicado en 2011

Combined sputum hypermethylation and eNose analysis for lung cancer diagnosis.

artículo científico publicado en 2014

Comparative Analysis of Urine Fractions for Optimal Bladder Cancer Detection Using DNA Methylation Markers

scientific article published on 02 April 2020

Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16/18 genotyping for the detection of cervical (pre)cancer in high-risk HPV-positive women of a gynecologic outpatient population (COMETH study).

artículo científico publicado en 2015

Complementarity between miRNA expression analysis and DNA methylation analysis in hrHPV-positive cervical scrapes for the detection of cervical disease

scientific article published on 08 April 2019

Comprehensive CADM1 promoter methylation analysis in NSCLC and normal lung specimens.

artículo científico publicado en 2010

Comprehensive analysis of human papillomavirus prevalence and the potential role of low-risk types in verrucous carcinoma

artículo científico

DNA hypermethylation analysis in sputum for the diagnosis of lung cancer: training validation set approach.

artículo científico publicado en 2015

DNA hypermethylation analysis in sputum of asymptomatic subjects at risk for lung cancer participating in the NELSON trial: argument for maximum screening interval of 2 years

artículo científico publicado en 2016

DNA methylation markers for endometrial cancer detection in minimally invasive samples: a systematic review

scientific article published on 17 September 2020

DNA methylation markers have universal prognostic value for anal cancer risk in HIV-negative and HIV-positive individuals

artículo científico publicado en 2021

DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery

scientific article published on 11 August 2020

Detection limits of DNA copy number alterations in heterogeneous cell populations

artículo científico publicado en 2012

Detection of hypermethylated genes as markers for cervical screening in women living with HIV

article

Development of a multiplex methylation-specific PCR as candidate triage test for women with an HPV-positive cervical scrape

artículo científico publicado en 2012

Development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of HPV16- and HPV18-induced infections and disease

artículo científico publicado en 2017

Differential In Vitro Immortalization Capacity of Eleven (Probable) High-Risk Human Papillomavirus Types

artículo científico publicado en 2014

Differential in vitro immortalization capacity of eleven (probable) [corrected] high-risk human papillomavirus types

artículo científico publicado en 2013

Disc large 1 expression is altered by human papillomavirus E6/E7 proteins in organotypic cultures of human keratinocytes

artículo científico publicado en 2015

Down-regulation of GATA-3 expression during human papillomavirus-mediated immortalization and cervical carcinogenesis

artículo científico publicado en 2002

EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration

artículo científico publicado en 2009

Elevated hTERT mRNA levels: A potential determinant of bronchial squamous cell carcinoma (in situ).

artículo científico publicado en 2004

Epigenetic markers for early detection of nasopharyngeal carcinoma in a high risk population. ⬇️

artículo científico publicado en 2011

Ets proteins: new factors that regulate immunoglobulin heavy-chain gene expression

artículo científico publicado en 1993

Evaluation of six methylation markers derived from genome-wide screens for detection of cervical precancer and cancer

artículo científico publicado en 2020

FAM19A4 methylation analysis in self-samples compared with cervical scrapes for detecting cervical (pre)cancer in HPV-positive women

artículo científico publicado en 2016

FAM19A4/miR124-2 methylation analysis as a triage test for HPV-positive women: cross-sectional and longitudinal data from a Dutch screening cohort

artículo científico publicado en 2020

FAM19A4/miR124-2 methylation in invasive cervical cancer: A retrospective cross-sectional worldwide study

artículo científico publicado en 2019

Focal aberrations indicate EYA2 and hsa-miR-375 as oncogene and tumor suppressor in cervical carcinogenesis

artículo científico publicado en 2012

Focal chromosomal copy number aberrations in cancer-Needles in a genome haystack

artículo científico publicado en 2014

Follow-up of high-risk HPV positive women by combined cytology and bi-marker CADM1/MAL methylation analysis on cervical scrapes.

artículo científico publicado en 2015

Functional Screen for microRNAs Suppressing Anchorage-Independent Growth in Human Cervical Cancer Cells

artículo científico publicado en 2022

Gene expression profiling to identify markers associated with deregulated hTERT in HPV-transformed keratinocytes and cervical cancer

artículo científico publicado en 2008

Gene-dosage dependent overexpression at the 13q amplicon identifies DIS3 as candidate oncogene in colorectal cancer progression.

artículo científico publicado en 2014

Genome-wide DNA Methylation Profiling Reveals Methylation Markers Associated with 3q Gain for Detection of Cervical Precancer and Cancer.

artículo científico publicado en 2017

Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma

artículo científico publicado en 2016

Genome-wide microRNA analysis of HPV-positive self-samples yields novel triage markers for early detection of cervical cancer.

artículo científico publicado en 2018

Genomic profiling identifies common HPV-associated chromosomal alterations in squamous cell carcinomas of cervix and head and neck.

artículo científico publicado en 2009

Good performance of p16/ki-67 dual-stained cytology for surveillance of women treated for high-grade CIN.

artículo científico publicado en 2016

Gynaecological cancer: Novel molecular subtypes of cervical cancer - potential clinical consequences.

artículo científico publicado en 2017

HPV E4 expression and DNA hypermethylation of CADM1, MAL, and miR124-2 genes in cervical cancer and precursor lesions

scientific article published on 22 August 2018

HPV type-related chromosomal profiles in high-grade cervical intraepithelial neoplasia.

artículo científico publicado en 2012

HPV-mediated cervical carcinogenesis: concepts and clinical implications

artículo científico publicado en 2006

HPV-mediated transformation of the anogenital tract.

artículo científico publicado en 2005

HPV-negative carcinoma of the uterine cervix: a distinct type of cervical cancer with poor prognosis

artículo científico publicado en 2014

HPV16 variant analysis in primary and recurrent CIN2/3 lesions demonstrates presence of the same consensus variant

HPV16-Related Cervical Cancers and Precancers Have Increased Levels of Host Cell DNA Methylation in Women Living with HIV

artículo científico publicado en 2018

Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180

artículo científico publicado en 1998

High Levels of EBV-Encoded RNA 1 (EBER1) Trigger Interferon and Inflammation-Related Genes in Keratinocytes Expressing HPV16 E6/E7

artículo científico publicado en 2017

High-risk human papillomavirus-positive lung cancer: molecular evidence for a pattern of pulmonary metastasis.

artículo científico

Host Cell Deoxyribonucleic Acid Methylation Markers for the Detection of High-grade Anal Intraepithelial Neoplasia and Anal Cancer

artículo científico publicado en 2019

Host-cell DNA methylation patterns during high-risk HPV-induced carcinogenesis reveal a heterogeneous nature of cervical pre-cancer

artículo científico publicado en 2018

Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers.

artículo científico publicado en 2013

Identification and Validation of a 3-Gene Methylation Classifier for HPV-Based Cervical Screening on Self-Samples

artículo científico publicado en 2018

Identification of Deregulated Pathways, Key Regulators, and Novel miRNA-mRNA Interactions in HPV-Mediated Transformation

scientific article published on 16 March 2020

Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling

artículo científico

Immortalization capacity of HPV types is inversely related to chromosomal instability.

artículo científico publicado en 2016

Immortalization of oral keratinocytes by functional inactivation of the p53 and pRb pathways.

artículo científico publicado en 2010

Increased gene copy numbers at chromosome 20q are frequent in both squamous cell carcinomas and adenocarcinomas of the cervix

artículo científico publicado en 2006

Integrated genomic and transcriptional profiling identifies chromosomal loci with altered gene expression in cervical cancer

artículo científico publicado en 2008

Integrated human papillomavirus type 16 and loss of heterozygosity at 11q22 and 18q21 in an oral carcinoma and its derivative cell line.

artículo científico publicado en 1995

Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer

artículo científico publicado en 2015

Lactate transporters and vascular factors in HPV-induced squamous cell carcinoma of the uterine cervix.

artículo científico publicado en 2014

Localization of E2A mRNA expression in developing and adult rat tissues

artículo científico publicado en 1993

Long-term CIN3+ risk of HPV positive women after triage with FAM19A4/miR124-2 methylation analysis

scientific article published on 08 June 2019

Longitudinal assessment of DNA methylation changes during HPVE6E7-induced immortalization of primary keratinocytes.

artículo científico publicado en 2015

MAL promoter hypermethylation as a novel prognostic marker in gastric cancer

artículo científico publicado en 2008

Management of high-risk HPV-positive women for detection of cervical (pre)cancer.

artículo científico publicado en 2016

Methylation analysis in urine fractions for optimal CIN3 and cervical cancer detection

scientific article published on 13 March 2020

Methylation analysis of the FAM19A4 gene in cervical scrapes is highly efficient in detecting cervical carcinomas and advanced CIN2/3 lesions.

artículo científico publicado en 2014

Methylation marker analysis and HPV16/18 genotyping in high-risk HPV positive self-sampled specimens to identify women with high grade CIN or cervical cancer.

artículo científico publicado en 2014

Methylation marker analysis of self-sampled cervico-vaginal lavage specimens to triage high-risk HPV-positive women for colposcopy.

artículo científico publicado en 2014

Methylation status of the E2 binding sites of HPV16 in cervical lesions determined with the Luminex® xMAP™ system.

artículo científico publicado en 2011

Methylation-mediated repression of PRDM14 contributes to apoptosis evasion in HPV-positive cancers.

artículo científico publicado en 2014

Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer.

artículo científico publicado en 2010

Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis

artículo científico publicado en 2013

Methylation-specific digital karyotyping of HPV16E6E7-expressing human keratinocytes identifies novel methylation events in cervical carcinogenesis

artículo científico publicado en 2013

Mining for viral fragments in methylation enriched sequencing data

artículo científico publicado en 2015

Molecular events leading to HPV-induced high grade neoplasia

artículo científico publicado en 2016

Molecular heterogeneity in human papillomavirus-dependent and -independent vulvar carcinogenesis.

artículo científico publicado en 2018

Non-invasive detection of endometrial cancer by DNA methylation analysis in urine

artículo científico publicado en 2020

Non-random allelic losses at 3p, 11p and 13q during HPV-mediated immortalization and concomitant loss of terminal differentiation of human keratinocytes.

artículo científico publicado en 1998

Oncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression

artículo científico publicado en 2015

Oncolytic adenovirus expressing a p53 variant resistant to degradation by HPV E6 protein exhibits potent and selective replication in cervical cancer.

artículo científico publicado en 2005

PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitro

artículo científico publicado en 2011

Performance of CADM1/MAL-methylation analysis for monitoring of women treated for high-grade CIN.

artículo científico publicado en 2016

Point-of-care CRISPR/Cas nucleic acid detection: Recent advances, challenges and opportunities

artículo científico publicado en 2020

Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7.

artículo científico publicado en 2012

Prevalence of Epstein-Barr virus in oral squamous cell carcinomas, premalignant lesions and normal mucosa--a study using the polymerase chain reaction.

artículo científico publicado en 1997

Prevalence of Neovaginal High-Risk Human Papillomavirus Among Transgender Women in The Netherlands.

artículo científico publicado en 2016

Promoter methylation analysis of WNT/β-catenin signaling pathway regulators to detect adenocarcinoma or its precursor lesion of the cervix.

artículo científico publicado en 2011

Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas ⬇️

artículo científico publicado en 2013

Quantitative reverse transcription-polymerase chain reaction measurement of HASH1 (ASCL1), a marker for small cell lung carcinomas with neuroendocrine features

artículo científico publicado en 2002

Repression of MAL tumour suppressor activity by promoter methylation during cervical carcinogenesis.

artículo científico publicado en 2009

Role of human papillomaviruses in cancer of the respiratory and upper digestive tract.

artículo científico publicado en 1997

Selection of women at risk for cervical cancer in an HIV-infected South African population.

artículo científico publicado en 2017

Sequential gene promoter methylation during HPV-induced cervical carcinogenesis

artículo científico publicado en 2007

Somatic mutation in PIK3CA is a late event in cervical carcinogenesis

artículo científico publicado en 2015

Specific betapapillomaviruses associated with squamous cell carcinoma of the skin inhibit UVB-induced apoptosis of primary human keratinocytes

scientific article published on 01 September 2008

Symptomatic HPV-related neovaginal lesions in transgender women: case series and review of literature.

artículo científico publicado en 2016

TSLC1 gene silencing in cervical cancer cell lines and cervical neoplasia

artículo científico publicado en 2004

Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA

artículo científico publicado en 1998

Telomerase activity in high-grade cervical lesions is associated with allelic imbalance at 6Q14-22.

artículo científico publicado en 2003

Telomerase suppression by chromosome 6 in a human papillomavirus type 16-immortalized keratinocyte cell line and in a cervical cancer cell line

artículo científico publicado en 2001

The Origin of Tumor DNA in Urine of Urogenital Cancer Patients: Local Shedding and Transrenal Excretion

artículo científico publicado en 2021

The diagnostic accuracy of methylation markers in urine for the detection of bladder cancer: a systematic review

artículo científico publicado en 2018

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer

artículo científico publicado en 2009

The effect of ART on cervical cancer precursor lesions.

artículo científico publicado en 2017

The functional role of Notch signaling in HPV-mediated transformation is dose-dependent and linked to AP-1 alterations

scientific article published on 24 January 2012

The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation.

artículo científico publicado en 2006

The use of host cell DNA methylation analysis in the detection and management of women with advanced cervical intraepithelial neoplasia: a review

artículo científico publicado en 2020

The use of molecular markers for cervical screening of women living with HIV in South Africa

scientific article published on 01 November 2019

Three sensitive methods for the detection of cytomegalovirus in lung tissue of patients with interstitial pneumonitis

artículo científico publicado en 1990

Three-tiered score for Ki-67 and p16 improves accuracy and reproducibility of grading CIN lesions

artículo científico publicado en 2018

Transition of human papillomavirus type 16 and 18 transfected human foreskin keratinocytes towards immortality: activation of telomerase and allele losses at 3p, 10p, 11q and/or 18q.

artículo científico publicado en 1996

Triage by methylation-marker testing versus cytology in women who test HPV-positive on self-collected cervicovaginal specimens (PROHTECT-3): a randomised controlled non-inferiority trial

artículo científico publicado en 2014

Triage of high-risk HPV-positive women in population-based screening by miRNA expression analysis in cervical scrapes; a feasibility study.

artículo científico publicado en 2018

Validation of the FAM19A4/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical (pre)cancer in HPV-positive women

artículo científico publicado en 2016

Viral E6-E7 transcription in the basal layer of organotypic cultures without apparent p21cip1 protein precedes immortalization of human papillomavirus type 16- and 18-transfected human keratinocytes

artículo científico publicado en 1998

[Human papillomavirus and the development of cervical cancer: concept of carcinogenesis]

scientific article published on 01 August 2000

hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis

artículo científico publicado en 2010

miR-9-5p Exerts a Dual Role in Cervical Cancer and Targets Transcription Factor TWIST1

artículo científico publicado en 2019

tigaR: integrative significance analysis of temporal differential gene expression induced by genomic abnormalities

artículo científico publicado en 2014

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