Lista de obras -

A new ex vivo method to evaluate the performance of candidate MRI contrast agents: a proof-of-concept study.

artículo científico publicado en 2014

A novel bio-functional material based on mammalian cell aggresomes.

artículo científico publicado en 2015

AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells.

artículo científico publicado en 2018

Activated N-ras oncogene and N-ras proto-oncogene act through the same pathway for in vivo tumorigenesis

scientific article published on 01 September 1996

Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment.

artículo científico

BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency

scientific article published on 01 December 2003

BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes

article

Biological assessment of self-assembled polymeric micelles for pulmonary administration of insulin.

artículo científico publicado en 2015

Brush border myosin Ia has tumor suppressor activity in the intestine.

artículo científico publicado en 2012

CD300 heterocomplexes, a new and family-restricted mechanism for myeloid cell signaling regulation.

artículo científico publicado en 2010

Cancer stem cells and personalized cancer nanomedicine.

artículo científico publicado en 2016

Cloning and characterization of CD300d, a novel member of the human CD300 family of immune receptors.

artículo científico publicado en 2012

Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profile.

artículo científico publicado en 2015

Dynamism, Sensitivity, and Consequences of Mesenchymal and Stem-Like Phenotype of Cancer Cells

article

EMT blockage strategies: Targeting Akt dependent mechanisms for breast cancer metastatic behaviour modulation

artículo científico publicado en 2015

EPH receptors in cancer.

artículo científico publicado en 2008

EPHB4 and survival of colorectal cancer patients.

artículo científico publicado en 2006

Extracellular Vesicles as Drug Delivery Systems in Cancer

artículo científico publicado en 2020

Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells

artículo científico publicado en 2015

Frameshift mutations in Fas, Apaf-1 and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype

artículo científico publicado en 2000

Frequent ki-ras mutations in gastric tumors of the MSI phenotype

article

Gains of the relative genomic content of erbB-1 and erbB-2 in prostate carcinoma and their association with metastasis

artículo científico publicado en 1999

Generation and characterization of orthotopic murine models for endometrial cancer.

artículo científico publicado en 2011

Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families

article

High EPHB2 mutation rate in gastric but not endometrial tumors with microsatellite instability.

artículo científico publicado en 2006

Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.

artículo científico publicado en 2015

Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target.

artículo científico publicado en 2012

Intracellular Delivery of Anti-SMC2 Antibodies against Cancer Stem Cells

artículo científico publicado en 2020

Intracellular targeting of CD44+ cells with self-assembling, protein only nanoparticles

artículo científico publicado en 2014

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

article

Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors.

artículo científico publicado en 2005

Medical-grade silicone induces release of proinflammatory cytokines in peripheral blood mononuclear cells without activating T cells

artículo científico publicado en 2009

Myo5b knockout mice as a model of microvillus inclusion disease.

artículo científico publicado en 2015

Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT

artículo científico publicado en 2006

Nanotechnology-based approaches for treating lysosomal storage disorders, a focus on Fabry disease

artículo científico publicado en 2020

Over-expression of epidermal growth factor receptor and c-erbB2/neu but not of int-2 genes in benign prostatic hyperplasia by means of semi-quantitative PCR

scientific article published on 01 May 1998

Overexpression of the immunoreceptor CD300f has a neuroprotective role in a model of acute brain injury.

artículo científico publicado en 2011

PAR-5 is a PARty hub in the germline: Multitask proteins in development and disease.

artículo científico publicado en 2013

Prognostic value of immunohistochemical expression of the c-erbB-2 oncoprotein in metastasic prostate cancer

artículo científico publicado en 1999

Promoter demethylation in MMTV/N-rasN transgenic mice required for transgene expression and tumorigenesis

scientific article published on 01 October 1995

RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.

artículo científico publicado en 2014

SMAD4 as a Prognostic Marker in Colorectal Cancer

artículo científico publicado en 2005

SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations.

artículo científico publicado en 2014

Self-assembly PEGylation assists SLN-paclitaxel delivery inducing cancer cell apoptosis upon internalization.

artículo científico publicado en 2016

Semisynthesis, cytotoxic activity, and oral availability of new lipophilic 9-substituted camptothecin derivatives.

artículo científico publicado en 2013

Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis

artículo científico publicado en 2006

Somatic mutations in mitochondrial DNA do not associate with nuclear microsatellite instability in gastrointestinal cancer

artículo científico publicado en 2000

Strategies for the production of difficult-to-express full-length eukaryotic proteins using microbial cell factories: production of human alpha-galactosidase A.

artículo científico publicado en 2015

Surface-modified silica nanoparticles for tumor-targeted delivery of camptothecin and its biological evaluation.

artículo científico publicado en 2011

The 14-3-3 gene par-5 is required for germline development and DNA damage response in Caenorhabditis elegans.

artículo científico publicado en 2012

The Biological Potential Hidden in Inclusion Bodies

artículo científico publicado en 2020

The Receptor CMRF35-Like Molecule-1 (CLM-1) Enhances the Production of LPS-Induced Pro-Inflammatory Mediators during Microglial Activation.

artículo científico publicado en 2015

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

artículo científico publicado en 2009

Transforming pathways unleashed by a HDAC2 mutation in human cancer.

artículo científico publicado en 2008

Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics.

artículo científico

α-Galactosidase-A Loaded-Nanoliposomes with Enhanced Enzymatic Activity and Intracellular Penetration

artículo científico publicado en 2016

Lista de obras de

A new ex vivo method to evaluate the performance of candidate MRI contrast agents: a proof-of-concept study.

A novel bio-functional material based on mammalian cell aggresomes.

AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells.

Activated N-ras oncogene and N-ras proto-oncogene act through the same pathway for in vivo tumorigenesis

Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment.

BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency

BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes

Biological assessment of self-assembled polymeric micelles for pulmonary administration of insulin.

Brush border myosin Ia has tumor suppressor activity in the intestine.

CD300 heterocomplexes, a new and family-restricted mechanism for myeloid cell signaling regulation.

Cancer stem cells and personalized cancer nanomedicine.

Cloning and characterization of CD300d, a novel member of the human CD300 family of immune receptors.

Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profile.

Dynamism, Sensitivity, and Consequences of Mesenchymal and Stem-Like Phenotype of Cancer Cells

EMT blockage strategies: Targeting Akt dependent mechanisms for breast cancer metastatic behaviour modulation

EPH receptors in cancer.

EPHB4 and survival of colorectal cancer patients.

Extracellular Vesicles as Drug Delivery Systems in Cancer

Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells

Frameshift mutations in Fas, Apaf-1 and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype

Frequent ki-ras mutations in gastric tumors of the MSI phenotype

Gains of the relative genomic content of erbB-1 and erbB-2 in prostate carcinoma and their association with metastasis

Generation and characterization of orthotopic murine models for endometrial cancer.

Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families

High EPHB2 mutation rate in gastric but not endometrial tumors with microsatellite instability.

Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.

Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target.

Intracellular Delivery of Anti-SMC2 Antibodies against Cancer Stem Cells

Intracellular targeting of CD44+ cells with self-assembling, protein only nanoparticles

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors.

Medical-grade silicone induces release of proinflammatory cytokines in peripheral blood mononuclear cells without activating T cells

Myo5b knockout mice as a model of microvillus inclusion disease.

Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT

Nanotechnology-based approaches for treating lysosomal storage disorders, a focus on Fabry disease

Over-expression of epidermal growth factor receptor and c-erbB2/neu but not of int-2 genes in benign prostatic hyperplasia by means of semi-quantitative PCR

Overexpression of the immunoreceptor CD300f has a neuroprotective role in a model of acute brain injury.

PAR-5 is a PARty hub in the germline: Multitask proteins in development and disease.

Prognostic value of immunohistochemical expression of the c-erbB-2 oncoprotein in metastasic prostate cancer

Promoter demethylation in MMTV/N-rasN transgenic mice required for transgene expression and tumorigenesis

RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.

SMAD4 as a Prognostic Marker in Colorectal Cancer

SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations.

Self-assembly PEGylation assists SLN-paclitaxel delivery inducing cancer cell apoptosis upon internalization.

Semisynthesis, cytotoxic activity, and oral availability of new lipophilic 9-substituted camptothecin derivatives.

Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis

Somatic mutations in mitochondrial DNA do not associate with nuclear microsatellite instability in gastrointestinal cancer

Strategies for the production of difficult-to-express full-length eukaryotic proteins using microbial cell factories: production of human alpha-galactosidase A.

Surface-modified silica nanoparticles for tumor-targeted delivery of camptothecin and its biological evaluation.

The 14-3-3 gene par-5 is required for germline development and DNA damage response in Caenorhabditis elegans.

The Biological Potential Hidden in Inclusion Bodies

The Receptor CMRF35-Like Molecule-1 (CLM-1) Enhances the Production of LPS-Induced Pro-Inflammatory Mediators during Microglial Activation.

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

Transforming pathways unleashed by a HDAC2 mutation in human cancer.

Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics.

α-Galactosidase-A Loaded-Nanoliposomes with Enhanced Enzymatic Activity and Intracellular Penetration