Filtros de búsqueda

Lista de obras de

A 17-gene stemness score for rapid determination of risk in acute leukaemia

artículo científico publicado en 2016

A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia

artículo científico publicado en 2007

A catalyst for change: the European cancer Patient's Bill of Rights

artículo científico publicado en 2014

A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects

artículo científico publicado en 2008

A one-mutation mathematical model can explain the age incidence of acute myeloid leukemia with mutated nucleophosmin (NPM1).

artículo científico publicado en 2008

A phase 2 study of the oral farnesyltransferase inhibitor tipifarnib in patients with refractory or relapsed acute myeloid leukemia.

artículo científico publicado en 2007

A phase I first-in-human study with tefinostat - a monocyte/macrophage targeted histone deacetylase inhibitor - in patients with advanced haematological malignancies

artículo científico publicado en 2013

A randomized multicenter comparison of CD34(+)-selected progenitor cells from blood vs from bone marrow in recipients of HLA-identical allogeneic transplants for hematological malignancies

artículo científico publicado en 2003

A series of reviews on "Hematologic Disease at Older Age".

artículo científico publicado en 2017

A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia

artículo científico publicado en 2014

A standardized microarray assay for the independent gene expression markers in AML: EVI1 and BAALC.

artículo científico publicado en 2013

A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia

artículo científico publicado en 2010

ABCB1 gene polymorphisms are not associated with treatment outcome in elderly acute myeloid leukemia patients

artículo científico publicado en 2006

AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance.

artículo científico publicado en 2009

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion

artículo científico publicado en 2005

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

artículo científico publicado en 2010

Acquired mutations in ASXL1 in acute myeloid leukemia: prevalence and prognostic value

artículo científico publicado el 4 de noviembre de 2011

Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value

artículo científico publicado en 2010

Acute myeloid leukemia and acute promyelocytic leukemia.

artículo científico publicado en 2003

Acute myeloid leukemia and the position of autologous stem cell transplantation

artículo científico publicado en 2007

Acute myeloid leukemia with monosomal karyotype at the far end of the unfavorable prognostic spectrum

artículo científico publicado el 1 de abril de 2011

Acute myeloid leukemia: the challenge of capturing disease variety

artículo científico publicado en 2008

Aerosolized liposomal amphotericin B for the prevention of invasive pulmonary aspergillosis during prolonged neutropenia: a randomized, placebo-controlled trial

artículo científico publicado en 2008

Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia

artículo científico publicado en 2009

All-trans retinoic acid with daunorubicin or idarubicin for risk-adapted treatment of acute promyelocytic leukaemia: a matched-pair analysis of the PETHEMA LPA-2005 and IC-APL studies

artículo científico publicado en 2015

Antithymocyteglobulin as prophylaxis of graft failure and graft-versus-host disease in recipients of partially T-cell—depleted grafts from matched unrelated donors: A dose-finding study

artículo científico publicado el 1 de noviembre de 2003

Autologous stem cell transplantation in the treatment of adults with acute myeloid leukaemia

artículo científico publicado en 2005

Azacitidine maintenance after intensive chemotherapy improves DFS in older AML patients

artículo científico publicado en 2019

Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia

artículo científico publicado en 2012

Biallelic mutations in the CEBPA gene and low CEBPA expression levels as prognostic markers in intermediate-risk AML.

artículo científico publicado en 2003

Blood's 70th anniversary: a rich history

artículo científico publicado en 2015

CD34-related coexpression of MDR1 and BCRP indicates a clinically resistant phenotype in patients with acute myeloid leukemia (AML) of older age.

artículo científico publicado en 2007

Candida krusei transmission among hematology patients resolved by adapted antifungal prophylaxis and infection control measures

artículo científico publicado en 2006

Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based regimens

artículo científico publicado el 8 de diciembre de 2010

Clinical significance of complex karyotype at diagnosis in pediatric and adult patients with de novo acute promyelocytic leukemia treated with ATRA and chemotherapy

artículo científico publicado en 2018

Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia

artículo científico publicado en 2019

Correction

scholarly article published in Journal of Experimental Medicine

Criteria for defining a complete remission in acute myeloid leukaemia revisited. An analysis of patients treated in HOVON-SAKK co-operative group studies

artículo científico publicado en 2005

Current challenges in clinical development of "targeted therapies": the case of acute myeloid leukemia

artículo científico publicado en 2015

Cytarabine dose for acute myeloid leukemia

artículo científico publicado en 2011

Deregulated expression of EVI1 defines a poor prognostic subset of MLL-rearranged acute myeloid leukemias: a study of the German-Austrian Acute Myeloid Leukemia Study Group and the Dutch-Belgian-Swiss HOVON/SAKK Cooperative Group

artículo científico publicado en 2012

Detection of CEBPA double mutants in acute myeloid leukemia using a custom gene expression array

artículo científico publicado en 2013

Detection of mutant NPM1 mRNA in acute myeloid leukemia using custom gene expression arrays

artículo científico publicado en 2013

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

artículo científico publicado en 2016

Dick W. van Bekkum, 1925-2015.

artículo científico publicado en 2015

Differential regulation of Foxo3a target genes in erythropoiesis

artículo científico

Dirk Willem van Bekkum: a pioneer in haematology, transplantation and radiobiology (1925-2015).

artículo científico publicado en 2015

Disseminated intravascular coagulation at diagnosis is a strong predictor for both arterial and venous thrombosis in newly diagnosed acute myeloid leukemia

artículo científico publicado en 2016

Distinct expression profiles of the peripheral cannabinoid receptor in lymphoid tissues depending on receptor activation status

artículo científico publicado en 2004

Dose-finding study of imatinib in combination with intravenous cytarabine: feasibility in newly diagnosed patients with chronic myeloid leukemia

artículo científico publicado en 2008

Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome

artículo científico publicado en 2009

Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia

artículo científico publicado en 2015

Dynamics of protein binding to telomeres in living cells: implications for telomere structure and function

artículo científico publicado en 2004

Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia

artículo científico publicado en 2003

Efficacy of escalated imatinib combined with cytarabine in newly diagnosed patients with chronic myeloid leukemia

artículo científico publicado en 2009

Empiric definition of eligibility criteria for clinical trials in relapsed/refractory acute myeloid leukemia: analysis of 1,892 patients from HOVON/SAKK and SWOG.

artículo científico publicado en 2015

Evidence for acute neurotoxicity after chemotherapy

artículo científico publicado el 1 de diciembre de 2010

FLT3 inhibition as a targeted therapy for acute myeloid leukemia

artículo científico publicado en 2009

Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence

artículo científico publicado en 2005

Flt3 ligand expands lymphoid progenitors prior to recovery of thymopoiesis and accelerates T cell reconstitution after bone marrow transplantation

artículo científico publicado en 2007

FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1

artículo científico publicado en 2004

Gemtuzumab ozogamicin as postremission treatment in AML at 60 years of age or more: results of a multicenter phase 3 study

artículo científico publicado en 2010

Gemtuzumab ozogamicin in acute myeloid leukemia: a remarkable saga about an active drug

artículo científico publicado en 2013

Gene expression profiling in acute myeloid leukemia

artículo científico publicado en 2005

Gene transactivation without direct DNA binding defines a novel gain-of-function for PML-RARalpha

artículo científico publicado en 2007

Germline loss ofMBD4predisposes to leukaemia due to a mutagenic cascade driven by 5mC

HeatMapper: powerful combined visualization of gene expression profile correlations, genotypes, phenotypes and sample characteristics

artículo científico publicado en 2006

Hematopoietic cells expressing the peripheral cannabinoid receptor migrate in response to the endocannabinoid 2-arachidonoylglycerol

artículo científico publicado en 2002

Hierarchical Bayesian formulations for selecting variables in regression models

artículo científico

High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patients

artículo científico publicado en 2003

High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated.

artículo científico publicado en 2008

High INDO (indoleamine 2,3-dioxygenase) mRNA level in blasts of acute myeloid leukemic patients predicts poor clinical outcome

artículo científico publicado en 2008

High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia.

artículo científico publicado en 2010

High prognostic impact of flow cytometric minimal residual disease detection in acute myeloid leukemia: data from the HOVON/SAKK AML 42A study

artículo científico publicado en 2013

High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia

artículo científico publicado en 2015

High-dose daunorubicin in older patients with acute myeloid leukemia

artículo científico publicado en 2009

How I treat the older patient with acute myeloid leukemia

artículo científico publicado en 2014

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study

artículo científico publicado en 2013

Identification of molecular predictors of response in a study of tipifarnib treatment in relapsed and refractory acute myelogenous leukemia

artículo científico publicado en 2007

Impaired health-related quality of life in acute myeloid leukemia survivors: a single-center study

artículo científico publicado en 2014

Impaired recovery of Epstein-Barr virus (EBV)--specific CD8+ T lymphocytes after partially T-depleted allogeneic stem cell transplantation may identify patients at very high risk for progressive EBV reactivation and lymphoproliferative disease

artículo científico publicado en 2003

Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL.

artículo científico publicado en 2013

Including historical data in the analysis of clinical trials: Is it worth the effort?

artículo científico publicado en 2017

Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations

artículo científico publicado en 2014

Integrative prognostic risk score in acute myeloid leukemia with normal karyotype

artículo científico publicado el 3 de marzo de 2011

Interleukin-7 improves T-cell recovery after experimental T-cell-depleted bone marrow transplantation in T-cell-deficient mice by strong expansion of recent thymic emigrants

artículo científico publicado en 2003

Introduction to a review series on myelodysplastic syndromes

scientific article published on 22 January 2019

Introduction to the review series on leukemic stem cells.

artículo científico publicado en 2017

Keratinocyte growth factor improves allogeneic bone marrow engraftment through a CD4+Foxp3+ regulatory T cell-dependent mechanism

artículo científico publicado en 2009

Large-scale identification of novel potential disease loci in mouse leukemia applying an improved strategy for cloning common virus integration sites

artículo científico publicado en 2002

Leukemic stem cell frequency: a strong biomarker for clinical outcome in acute myeloid leukemia

artículo científico publicado en 2014

Low expression of MDS1-EVI1–like-1 (MEL1) and EVI1-like-1 (EL1) genes in favorable-risk acute myeloid leukemia

artículo científico publicado el 1 de noviembre de 2003

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

artículo científico publicado en 2018

MPL expression on AML blasts predicts peripheral blood neutropenia and thrombocytopenia

artículo científico publicado en 2016

Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet

artículo científico publicado en 2008

Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet

scholarly article by Miguel A Sanz et al published 11 April 2019 in Blood

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice

artículo científico publicado en 2011

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia

artículo científico publicado en 2008

Minimal residual disease in chronic myeloid leukemia

artículo científico publicado en 2003

Minimal residual disease quantification in patients with acute myeloid leukaemia and inv(16)/CBFB-MYH11 gene fusion

artículo científico publicado en 2002

Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal.

artículo científico publicado en 2009

Molecular Minimal Residual Disease in Acute Myeloid Leukemia

Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia

artículo científico publicado el 5 de abril de 2012

Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways

artículo científico publicado en 2014

Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance

artículo científico publicado en 2005

Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients

artículo científico publicado en 2012

PBX3 is an important cofactor of HOXA9 in leukemogenesis

artículo científico publicado en 2012

PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells

artículo científico publicado en 2012

Paradoxical effects of interleukin‐10 on the maturation of murine myeloid dendritic cells

artículo científico publicado el 1 de octubre de 2003

Phase 1/2 study to assess the safety, efficacy, and pharmacokinetics of barasertib (AZD1152) in patients with advanced acute myeloid leukemia

artículo científico publicado en 2011

Phase I/II clinical study of Tosedostat, an inhibitor of aminopeptidases, in patients with acute myeloid leukemia and myelodysplasia

artículo científico publicado en 2010

Post-remission treatment with allogeneic stem cell transplantation in patients aged 60 years and older with acute myeloid leukaemia: a time-dependent analysis

artículo científico publicado en 2015

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

artículo científico publicado en 2008

Prevention of Epstein-Barr virus-lymphoproliferative disease by molecular monitoring and preemptive rituximab in high-risk patients after allogeneic stem cell transplantation

artículo científico publicado en 2002

Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukaemia study.

artículo científico publicado en 2014

Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy

artículo científico publicado en 2011

Prognostically useful gene-expression profiles in acute myeloid leukemia

artículo científico publicado en 2004

Publisher Correction: miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.

artículo científico publicado en 2018

Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia

artículo científico publicado en 2004

Relationship between event-free survival and overall survival in acute myeloid leukemia: a report from SWOG, HOVON/SAKK, and MRC/NCRI.

artículo científico publicado en 2016

Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom?

artículo científico publicado en 2007

Retroviral integration mutagenesis in mice and comparative analysis in human AML identify reduced PTP4A3 expression as a prognostic indicator

artículo científico publicado en 2011

Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

artículo científico publicado en 2003

Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome

artículo científico publicado en 2010

Role of allogeneic stem cell transplantation in current treatment of acute myeloid leukemia

artículo científico publicado en 2005

SNPExpress: integrated visualization of genome-wide genotypes, copy numbers and gene expression levels

artículo científico publicado en 2008

Sense and nonsense of high-dose cytarabine for acute myeloid leukemia

artículo científico

Significance of FAB subclassification of "acute myeloid leukemia, NOS" in the 2008 WHO classification: analysis of 5848 newly diagnosed patients

artículo científico publicado en 2013

Somatostatin is a selective chemoattractant for primitive (CD34(+)) hematopoietic progenitor cells

artículo científico publicado en 2002

Strict infection control measures do not prevent clonal spread of coagulase negative staphylococci colonizing central venous catheters in neutropenic hemato-oncologic patients

artículo científico publicado en 2003

Sustainability and affordability of cancer drugs: a novel pricing model

The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity

artículo científico publicado en 2004

The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells

artículo científico publicado en 2005

The European Cancer Patient's Bill of Rights, update and implementation 2016.

artículo científico publicado en 2016

The European LeukemiaNet AML Working Party consensus statement on allogeneic HSCT for patients with AML in remission: an integrated-risk adapted approach

artículo científico publicado en 2012

The Neo-Open Reading Frame Peptides That Comprise the Tumor Framome Are a Rich Source of Neoantigens for Cancer Immunotherapy

artículo científico publicado en 2024

The common viral insertion site Evi12 is located in the 5'-noncoding region of Gnn, a novel gene with enhanced expression in two subclasses of human acute myeloid leukemia

scientific journal article

The development and validation of a decision-analytic model representing the full disease course of acute myeloid leukemia

artículo científico publicado en 2013

The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies

artículo científico publicado en 2006

The emerging role of targeted therapy for hematologic malignancies: update on bortezomib and tipifarnib

artículo científico publicado en 2007

The impact of abn(17p) and monosomy -5/del(5q) on the prognostic value of the monosomal karyotype in acute myeloid leukemia

artículo científico publicado en 2013

The peripheral cannabinoid receptor Cb2, a novel oncoprotein, induces a reversible block in neutrophilic differentiation

artículo científico publicado en 2002

The peripheral cannabinoid receptor Cb2, frequently expressed on AML blasts, either induces a neutrophilic differentiation block or confers abnormal migration properties in a ligand-dependent manner

artículo científico publicado en 2004

The value of alloantibody detection in predicting response to HLA-matched platelet transfusions

artículo científico publicado en 2004

The value of allogeneic and autologous hematopoietic stem cell transplantation in prognostically favorable acute myeloid leukemia with double mutant CEBPA.

artículo científico publicado en 2013

The value of fludarabine in addition to ARA-C and G-CSF in the treatment of patients with high-risk myelodysplastic syndromes and AML in elderly patients

artículo científico publicado en 2003

The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis

artículo científico publicado en 2005

Therapeutic Advances in Acute Myeloid Leukemia

artículo científico publicado el 10 de enero de 2011

Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML.

artículo científico publicado en 2017

Therapy-related myeloid neoplasms in patients with acute promyelocytic leukemia treated with all-trans-retinoic Acid and anthracycline-based chemotherapy

artículo científico publicado en 2010

Translational control of putative protooncogene Nm23-M2 by cytokines via phosphoinositide 3-kinase signaling

artículo científico publicado en 2004

Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling

artículo científico publicado en 2014

Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors

artículo científico publicado en 2004

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.

artículo científico publicado en 2012

Various distinctive cytogenetic abnormalities in patients with acute myeloid leukaemia aged 60 years and older express adverse prognostic value: results from a prospective clinical trial

artículo científico publicado en 2006

miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia

artículo científico publicado en 2012