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1,3-Diphenyl-1H-pyrazole derivatives as a new series of potent PPARγ partial agonists.

artículo científico publicado en 2010

A novel adipokine CTRP1 stimulates aldosterone production

artículo científico publicado en 2008

A simple method to screen ligands of peroxisome proliferator-activated receptor delta.

artículo científico publicado en 2006

Adipocyte culture medium stimulates invasiveness of MDA-MB-231 cell via CCL20 production.

artículo científico publicado en 2009

Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells.

artículo científico

Adiponectin is a negative regulator of NK cell cytotoxicity.

artículo científico publicado en 2006

Adiponectin-activated AMPK stimulates dephosphorylation of AKT through protein phosphatase 2A activation.

artículo científico publicado en 2009

Anti-cancerous effect of cis-khellactone from Angelica amurensis through the induction of three programmed cell deaths.

artículo científico publicado en 2018

Antimelanogenic effect of 4-hydroxylonchocarpin through the inhibition of tyrosinase-related proteins and MAPK phosphatase

artículo científico publicado en 2016

Antinociceptive effect of amygdalin isolated from Prunus armeniaca on formalin-induced pain in rats.

artículo científico publicado en 2008

Antiobesity effect of baicalin involves the modulations of proadipogenic and antiadipogenic regulators of the adipogenesis pathway.

artículo científico publicado en 2009

Antiobesity effects of a sulfur compound thiacremonone mediated via down-regulation of serum triglyceride and glucose levels and lipid accumulation in the liver of db/db mice.

artículo científico publicado en 2012

Apolipoprotein A-I induces IL-10 and PGE2 production in human monocytes and inhibits dendritic cell differentiation and maturation.

artículo científico publicado en 2005

Apoptosis-inducing factor (AIF) inhibits protein synthesis by interacting with the eukaryotic translation initiation factor 3 subunit p44 (eIF3g)

artículo científico publicado en 2006

Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression.

artículo científico publicado en 2011

Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells.

artículo científico publicado en 2009

C1q/TNF-α-Related Protein 1 (CTRP1) Maintains Blood Pressure Under Dehydration Conditions

scientific article published on 01 August 2018

CTRP1 protects against diet-induced hyperglycemia by enhancing glycolysis and fatty acid oxidation

artículo científico publicado en 2015

Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity.

artículo científico publicado en 2013

Caspase-mediated cleavage and DNase activity of the translation initiation factor 3, subunit G (eIF3g).

artículo científico publicado en 2013

Circulating CTRP1 Levels in Type 2 Diabetes and Their Association with FGF21

artículo científico publicado en 2016

Cloning and characterization of bovine interleukin-32 beta isoform.

artículo científico publicado en 2010

Cloning and expression of a cDNA encoding a novel protein serine/threonine kinase predominantly expressed in hematopoietic cells

scientific journal article

Combined Treatment of Herbal Mixture Extract H9 with Trastuzumab Enhances Anti-tumor Growth Effect

artículo científico publicado en 2015

Cryptotanshinone inhibits IgE‑mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine‑protein kinase phosphorylation in mast cells.

artículo científico publicado en 2018

Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity

artículo científico publicado en 2013

Dephosphorylation of CCAAT/enhancer-binding protein β by protein phosphatase 2A containing B56δ is required at the early time of adipogenesis.

artículo científico publicado en 2014

Depletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatases

artículo científico publicado en 2014

Development of suspension cell culture model to mimic circulating tumor cells

artículo científico publicado en 2017

Dexamethasone reverses TGF-beta-mediated inhibition of primary rat preadipocyte differentiation

scientific journal article

Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells.

artículo científico publicado en 2014

Effects of acupuncture on chronic corticosterone-induced depression-like behavior and expression of neuropeptide Y in the rats.

artículo científico publicado en 2009

Elevation of intracellular cyclic AMP inhibits NF-kappaB-mediated thymosin beta4 expression in melanoma cells

artículo científico publicado en 2009

Enhanced antitumor activity of vitamin C via p53 in cancer cells.

artículo científico publicado en 2012

Estradiol enhances CIP2A expression by the activation of p70 S6 kinase.

artículo científico publicado en 2014

Eupatolide inhibits the TGF-β1-induced migration of breast cancer cells via downregulation of SMAD3 phosphorylation and transcriptional repression of ALK5.

artículo científico publicado en 2017

Expression of human NDRG2 by myeloid dendritic cells inhibits down-regulation of activated leukocyte cell adhesion molecule (ALCAM) and contributes to maintenance of T cell stimulatory activity.

artículo científico publicado en 2007

Hypoxia-induced IL-32β increases glycolysis in breast cancer cells.

artículo científico publicado en 2014

IFITM6 expression is increased in macrophages of tumor-bearing mice.

artículo científico publicado en 2010

IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells

artículo científico publicado en 2016

IL-18 enhances ULBP2 expression through the MAPK pathway in leukemia cells.

artículo científico publicado en 2008

Identification of (beta-carboxyethyl)-rhodanine derivatives exhibiting peroxisome proliferator-activated receptor gamma activity.

artículo científico publicado en 2009

Identification of differentially-expressed genes by DNA methylation in cervical cancer.

artículo científico publicado en 2015

Increase in CIP2A expression is associated with doxorubicin resistance.

artículo científico

Inhibition of osteoclast differentiation by overexpression of NDRG2 in monocytes.

artículo científico publicado en 2015

Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines.

artículo científico publicado en 2016

Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function

artículo científico publicado en 2016

Interleukin 4-induced proliferation in normal human keratinocytes is associated with c-myc gene expression and inhibited by genistein

scientific article published on 01 September 1996

Interleukin-32α downregulates the activity of the B-cell CLL/lymphoma 6 protein by inhibiting protein kinase Cε-dependent SUMO-2 modification.

artículo científico publicado en 2014

Interleukin-32α modulates promyelocytic leukemia zinc finger gene activity by inhibiting protein kinase Cɛ-dependent sumoylation

artículo científico publicado en 2014

Interleukin-32β stimulates migration of MDA-MB-231 and MCF-7cells via the VEGF-STAT3 signaling pathway.

artículo científico publicado en 2013

Interleukin-32δ interacts with IL-32β and inhibits IL-32β-mediated IL-10 production

artículo científico publicado en 2013

KR33426, [2-(2,5-dichlorophenyl)-5-methyloxazol-4yl]carbonylguanidine, is a novel compound to be effective on mouse systemic lupus erythematosus.

artículo científico

Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer.

artículo científico publicado en 2016

Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins via AMP kinase activation

scientific article published on 28 January 2019

Klotho inhibits the capacity of cell migration and invasion in cervical cancer

artículo científico publicado en 2012

Luteolin supplementation modulates mammary tumor growth in C3H mice fed diet with high- and low-fat content.

artículo científico publicado en 2013

Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells.

artículo científico publicado en 2008

MiR-146a Regulates Migration and Invasion by Targeting NRP2 in Circulating-Tumor Cell Mimicking Suspension Cells

artículo científico publicado en 2020

Molecular Mechanisms and Emerging Therapeutics for Osteoporosis

artículo científico publicado en 2020

Molecular cloning and chromosomal localization of a human gene homologous to the murine R-PTP-kappa, a receptor-type protein tyrosine phosphatase

artículo científico publicado en 1997

N-myc downstream-regulated gene 2 (NDRG2) suppresses the epithelial-mesenchymal transition (EMT) in breast cancer cells via STAT3/Snail signaling

artículo científico publicado en 2014

NDRG2 controls COX-2/PGE₂-mediated breast cancer cell migration and invasion.

artículo científico publicado en 2014

NDRG2 gene expression in B16F10 melanoma cells restrains melanogenesis via inhibition of Mitf expression.

artículo científico publicado en 2008

Neuronatin Is Associated with an Anti-Inflammatory Role in the White Adipose Tissue.

artículo científico publicado en 2017

Nutrient/serum starvation derived TRIP-Br3 down-regulation accelerates apoptosis by destabilizing XIAP.

artículo científico publicado en 2015

Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.

artículo científico publicado en 2018

Optimization of an enzyme-linked immunosorbent assay to screen ligand of Peroxisome proliferator-activated receptor alpha.

artículo científico publicado en 2009

Osteopontin promotes the development of natural killer cells from hematopoietic stem cells.

artículo científico publicado en 2008

Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway

artículo científico publicado en 2016

SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity.

artículo científico publicado en 2015

SOCS1 induced by NDRG2 expression negatively regulates STAT3 activation in breast cancer cells.

artículo científico publicado en 2007

SUMOylation of RORalpha potentiates transcriptional activation function.

artículo científico publicado en 2008

Serum BAFF expression in patients with myasthenia gravis.

artículo científico

Shikonin inhibits adipogenesis by modulation of the WNT/β-catenin pathway.

artículo científico publicado en 2010

Silent mating-type information regulation 2 homolog 1 overexpression is an important strategy for the survival of adapted suspension tumor cells

scientific article published on 11 August 2019

Streamlined procedure for gene knockouts using all-in-one adenoviral CRISPR-Cas9

artículo científico publicado en 2019

TRIP-Br1 oncoprotein inhibits autophagy, apoptosis, and necroptosis under nutrient/serum-deprived condition.

artículo científico publicado en 2015

The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice.

artículo científico publicado en 2014

The biflavonoid amentoflavone induces apoptosis via suppressing E7 expression, cell cycle arrest at sub-G₁ phase, and mitochondria-emanated intrinsic pathways in human cervical cancer cells.

artículo científico publicado en 2011

The expression of BAFF in the muscles of patients with dermatomyositis.

artículo científico

The functional roles of PML nuclear bodies in genome maintenance.

artículo científico publicado en 2017

The interferon-inducible 9-27 gene modulates the susceptibility to natural killer cells and the invasiveness of gastric cancer cells.

artículo científico publicado en 2005

The mitochondrial pathway and reactive oxygen species are critical contributors to interferon-α/β-mediated apoptosis in Ubp43-deficient hematopoietic cells.

artículo científico publicado en 2012

Thiacremonone, a sulfur compound isolated from garlic, attenuates lipid accumulation partially mediated via AMPK activation in 3T3-L1 adipocytes.

artículo científico publicado en 2012

Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1 expression in adipose tissue.

artículo científico publicado en 2006

UVB-induced interleukin-18 production is downregulated by tannic acids in human HaCaT keratinocytes.

artículo científico publicado en 2006

Upregulation and secretion of macrophage inhibitory cytokine-1 (MIC-1) in gastric cancers.

artículo científico publicado en 2008

VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression

artículo científico publicado en 2003

Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function

scientific journal article

Von Hippel-Lindau regulates interleukin-32β stability in ovarian cancer cells.

artículo científico publicado en 2017