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15-Deoxy-Delta(12,14)-prostaglandin-J(2) reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1alpha degradation.

artículo científico publicado en 2009

Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice

scientific journal article

Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase.

artículo científico publicado en 2005

Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors

artículo científico publicado en 2020

Acute Vhl Gene Inactivation Induces Cardiac HIF-Dependent Erythropoietin Gene Expression

artículo científico publicado el 21 de julio de 2011

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

artículo científico publicado en 2008

Dithiocarbamates trigger differentiation and induction of CD11c gene through AP-1 in the myeloid lineage.

artículo científico publicado en 1996

Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension

scientific article published on 02 January 2001

From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on "New frontiers in cardiovascular research"

artículo científico publicado en 2016

Genetic evidence for a tumor suppressor role of HIF-2alpha.

artículo científico publicado en 2005

HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction

artículo científico publicado en 2015

HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5.

artículo científico publicado en 2012

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

artículo científico publicado en 2009

Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity.

artículo científico publicado en 2011

Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.

artículo científico publicado en 2002

Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor.

artículo científico publicado en 2009

Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1

artículo científico publicado en 2010

Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside

artículo científico publicado en 2015

Mitochondrial reprogramming through cardiac oxygen sensors in ischaemic heart disease

artículo científico publicado el 2 de agosto de 2010

Molecular pathways: hypoxia response in immune cells fighting or promoting cancer

artículo científico publicado en 2012

Mutant versions of von Hippel-Lindau (VHL) can protect HIF1α from SART1-mediated degradation in clear-cell renal cell carcinoma

artículo científico publicado en 2015

Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation

artículo científico publicado en 2014

Novel perspectives on the PHD-HIF oxygen sensing pathway in cardioprotection mediated by IPC and RIPC

artículo científico

Reduced intracellular oxidative metabolism promotes firm adhesion of human polymorphonuclear leukocytes to vascular endothelium under flow conditions

artículo científico publicado en 1997

Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms.

artículo científico publicado en 2003

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

artículo científico publicado en 2010

The HIF-1α Hypoxia Response in Tumor-Infiltrating T Lymphocytes Induces Functional CD137 (4-1BB) for Immunotherapy

artículo científico publicado en 2012

c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription.

artículo científico publicado en 2002