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6q deletion in Waldenström macroglobulinemia is associated with features of adverse prognosis

scientific article published on 01 January 2007

A Low Frequency of Losses in 11q Chromosome Is Associated with Better Outcome and Lower Rate of Genomic Mutations in Patients with Chronic Lymphocytic Leukemia.

artículo científico publicado en 2015

A high proportion of cells carrying trisomy 12 is associated with a worse outcome in patients with chronic lymphocytic leukemia

artículo científico publicado en 2015

A rare but recurrent t(8;13)(q24;q14) translocation in B-cell chronic lymphocytic leukaemia causingMYCup-regulation and concomitant loss ofPVT1,miR-15/16andDLEU7

A robust estimation of exon expression to identify alternative spliced genes applied to human tissues and cancer samples.

artículo científico publicado en 2014

Abnormalities on 1q and 7q are associated with poor outcome in sporadic Burkitt's lymphoma. A cytogenetic and comparative genomic hybridization study

artículo científico publicado en 2003

Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy.

artículo científico publicado en 2009

Alternating mini-BEAM/ESHAP as salvage therapy for refractory non-Hodgkin's lymphomas

artículo científico publicado en 1997

An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innovations in LEukemia study prephase.

artículo científico publicado en 2008

Analyse multiple disease subtypes and build associated gene networks using genome-wide expression profiles

artículo científico publicado en 2015

Analysis of chromosomal imbalances in an elderly woman with a giant cell tumour

scientific article published on 12 October 2005

Analysis of hematopoietic progenitor cells in patients with myelodysplastic syndromes according to their cytogenetic abnormalities

scientific article published on 01 November 2004

Application of FISH 7q in MDS patients without monosomy 7 or 7q deletion by conventional G-banding cytogenetics: does -7/7q- detection by FISH have prognostic value?

artículo científico publicado en 2013

Array comparative genomic hybridization identifies genetic regions associated with outcome in aggressive diffuse large B-cell lymphomas.

artículo científico publicado en 2009

Association between different risk factors and vascular accelerated ageing (EVA study): study protocol for a cross-sectional, descriptive observational study

scientific article published on 07 June 2016

Association between trisomy 8 and the immunophenotype of blast cells from acute leukemias secondary to a myelodysplastic syndrome or chronic myeloproliferative disorders

scientific article published on 01 May 1997

Automatic knowledge extraction in sequencing analysis with multiagent system and grid computing.

artículo científico publicado en 2012

Bone marrow fibrosis in myelodysplastic syndromes: a prospective evaluation including mutational analysis.

artículo científico publicado en 2016

Both expanded and uncultured mesenchymal stem cells from MDS patients are genomically abnormal, showing a specific genetic profile for the 5q- syndrome

artículo científico publicado en 2009

Cell cycle analysis of Waldenstrom's macroglobulinemia

artículo científico publicado en 2005

Central nervous system recurrence in adult patients with acute lymphoblastic leukemia: frequency and prognosis in 467 patients without cranial irradiation for prophylaxis

artículo científico publicado en 2006

Characterization by chromosome painting of balanced and unbalanced X chromosome translocations in myelodysplastic syndromes.

artículo científico

Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl

artículo científico publicado en 2006

Chromosomal abnormalities are related to location and grade of osteoarthritis

scientific article published on 01 December 2004

Chromosomal imbalances identified by comparative genomic hybridization in sporadic parathyroid adenomas

artículo científico publicado en 2002

Chromosome 14q32 translocations involving the immunoglobulin heavy chain locus in chronic lymphocytic leukaemia identify a disease subset with poor prognosis

scientific article published on 28 June 2008

Chromothripsis Is a Recurrent Genomic Abnormality in High-Risk Myelodysplastic Syndromes.

artículo científico publicado en 2016

Chronic lymphocytic leukemia: a clinical and molecular heterogenous disease.

artículo científico

Clonal myelodysplastic cells present in apheresis product before transplantation

artículo científico publicado en 1998

Comprehensive conventional and molecular cytogenetic characterization of B-CPAP, a human papillary thyroid carcinoma-derived cell line.

artículo científico publicado en 2004

Correlation of myelodysplastic syndromes with i(17)(q10) andTP53andSETBP1mutations

artículo científico publicado en 2015

Current opinion and consensus statement regarding the diagnosis, prognosis, and treatment of patients with essential thrombocythemia: a survey of the Spanish Group of Ph-negative Myeloproliferative Neoplasms (GEMFIN) using the Delphi method.

artículo científico publicado en 2016

Cytogenetic risk stratification in chronic myelomonocytic leukemia.

artículo científico publicado en 2010

DNA copy number profiling reveals different patterns of chromosomal instability within colorectal cancer according to the age of onset

artículo científico publicado en 2015

Deletions of the long arm of chromosome 7 in myeloid disorders: loss of band 7q32 implies worst prognosis

artículo científico publicado en 1996

Deregulation of genes related to iron and mitochondrial metabolism in refractory anemia with ring sideroblasts

artículo científico publicado en 2015

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling.

artículo científico publicado en 2010

Design and application of a 23-gene panel by next-generation sequencing for inherited coagulation bleeding disorders.

artículo científico publicado en 2016

Detection of the Mbcr/abl translocation in chronic myeloid leukemia by fluorescence in situ hybridization: comparison with conventional cytogenetics and implications for minimal residual disease detection

scientific article published on 01 February 1997

Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization

artículo científico publicado en 2001

Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms

artículo científico publicado en 2005

Effects of imatinib mesylate on normal bone marrow cells from chronic myeloid leukemia patients in complete cytogenetic response.

artículo científico publicado en 2008

Evaluation of Spanish Gaucher disease patients after a 6-month imiglucerase shortage

artículo científico publicado en 2010

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

artículo científico publicado en 2011

Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm

artículo científico publicado en 2013

Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice

artículo científico publicado el 11 de junio de 2012

Expression of VAV1 in the tumour microenvironment of glioblastoma multiforme.

artículo científico publicado en 2012

FISH analysis of hematological neoplasias with 1p36 rearrangements allows the definition of a cluster of 2.5 Mb included in the minimal region deleted in 1p36 deletion syndrome

artículo científico publicado en 2005

FISHing in the dark: How the combination of FISH and conventional karyotyping improves the diagnostic yield in CpG-stimulated chronic lymphocytic leukemia.

artículo científico publicado en 2016

Fluorescencein situhybridization analysis does not increase detection rate for trisomy 8 in chronic myelomonocytic leukemia

artículo científico publicado en 2014

Gene expression profile reveals deregulation of genes with relevant functions in the different subclasses of acute myeloid leukemia.

artículo científico publicado en 2005

Gene expression profiling in MDS and AML: potential and future avenues.

artículo científico publicado en 2011

Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals

artículo científico publicado en 2007

Genetic Abnormalities and Patterns of Antigenic Expression in Multiple Myeloma

artículo científico publicado en 2005

Genetic heterogeneity of BCR/ABL+ adult B-cell precursor acute lymphoblastic leukemia: impact on the clinical, biological and immunophenotypical disease characteristics

artículo científico publicado en 2005

Genome-Wide DNA Copy Number Analysis of Acute Lymphoblastic Leukemia Identifies New Genetic Markers Associated with Clinical Outcome

artículo científico publicado en 2016

Genome-wide profiling of methylation identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes.

artículo científico publicado en 2012

Genomic analysis of clonal eosinophils by CGH arrays reveals new genetic regions involved in chronic eosinophilia

artículo científico publicado en 2014

Geographic differences in the incidence of cytogenetic abnormalities of acute myelogenous leukemia (AML) in Spain

article

Heterogeneity of structural abnormalities in the 7q31.3∼q34 region in myeloid malignancies

artículo científico publicado en 2004

High-dose chemotherapy and immunotherapy in adult Burkitt lymphoma: comparison of results in human immunodeficiency virus-infected and noninfected patients.

artículo científico publicado en 2008

High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma.

artículo científico publicado en 2012

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

artículo científico publicado en 2016

Hyperdiploidy as a rare event that accompanies poor prognosis markers in CLL.

artículo científico publicado en 2016

Immunophenotypic and Cytogenetic Comparison of Waldenström's Macroglobulinemia with Splenic Marginal Zone Lymphoma

artículo científico publicado en 2005

Immunophenotypic characterisation of acute leukaemia after polycythemia vera

artículo científico publicado en 1993

Impact of adjunct cytogenetic abnormalities for prognostic stratification in patients with myelodysplastic syndrome and deletion 5q

artículo científico publicado en 2010

Impact of immunophenotype on prognosis of patients with myelodysplastic syndromes. Its value in patients without karyotypic abnormalities.

artículo científico publicado en 2004

Impact of transplant eligibility and availability of a human leukocyte antigen-identical matched related donor on outcome of older patients with acute lymphoblastic leukemia

artículo científico publicado en 2015

Incidence and clinicobiologic characteristics of leukemic B-cell chronic lymphoproliferative disorders with more than one B-cell clone

scientific article published on 26 June 2003

Incidence and prognostic impact of secondary cytogenetic aberrations in a series of 145 patients with mantle cell lymphoma.

artículo científico publicado en 2010

Incidence, clinical and biological characteristics and outcome of secondary acute lymphoblastic leukemia after solid organ or hematologic malignancy

artículo científico publicado en 2015

Inflammatory myofibroblastic tumor of bone: report of two cases with evidence of clonal chromosomal changes

artículo científico publicado en 1997

Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse.

artículo científico publicado en 2016

Interstitial 13q14 deletions detected in the karyotype and translocations with concomitant deletion at 13q14 in chronic lymphocytic leukemia: Different genetic mechanisms but equivalent poorer clinical outcome

artículo científico publicado en 2014

Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations

artículo científico publicado en 2016

Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.

artículo científico publicado en 2013

Lymphoid subsets in acute myeloid leukemias: increased number of cells with NK phenotype and normal T-cell distribution

artículo científico publicado en 1993

Mesenchymal stem cells from multiple myeloma patients display distinct genomic profile as compared with those from normal donors

scientific article published on 09 April 2009

MiRNA expression profile of chronic lymphocytic leukemia patients with 13q deletion.

artículo científico publicado en 2016

MicroRNA-223 is a novel negative regulator of HSP90B1 in CLL.

artículo científico publicado en 2015

Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome

scientific article published on 14 May 2009

Minimal residual disease evaluation by flow cytometry is a complementary tool to cytogenetics for treatment decisions in acute myeloid leukaemia.

artículo científico publicado en 2015

Mobilisation with G-CSF in healthy donors promotes a high but temporal deregulation of genes

article

Molecular analysis of ex-vivo CD133+ GBM cells revealed a common invasive and angiogenic profile but different proliferative signatures among high grade gliomas.

artículo científico publicado en 2010

Molecular characterization of chronic lymphocytic leukemia patients with a high number of losses in 13q14.

artículo científico publicado en 2012

Multicolor fluorescence in situ hybridization studies in multiple myeloma and monoclonal gammopathy of undetermined significance.

artículo científico

Mutation status and immunoglobulin gene rearrangements in patients from northwest and central region of Spain with chronic lymphocytic leukemia.

artículo científico publicado en 2014

Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome

scientific article published on 29 April 2014

NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome.

artículo científico publicado en 2012

Non-coding recurrent mutations in chronic lymphocytic leukaemia

artículo científico publicado en 2015

Novel genomic imbalances in B-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics.

artículo científico publicado en 2001

Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction

scientific article published on 27 May 2016

Population pharmacokinetics of doxorubicin and doxorubicinol in patients diagnosed with non-Hodgkin's lymphoma

artículo científico publicado en 2016

Prognostic impact of chromosomal translocations in myelodysplastic syndromes and chronic myelomonocytic leukemia patients. A study by the spanish group of myelodysplastic syndromes.

artículo científico publicado en 2015

Prognostic impact of the number of methylated genes in myelodysplastic syndromes and acute myeloid leukemias treated with azacytidine

artículo científico publicado en 2013

Prognostic significance of complex karyotype and monosomal karyotype in adult patients with acute lymphoblastic leukemia treated with risk-adapted protocols

artículo científico publicado en 2014

Prognostic significance of copy number alterations in adolescent and adult patients with precursor B acute lymphoblastic leukemia enrolled in PETHEMA protocols.

artículo científico publicado en 2015

Prognostic value of trisomy 8 as a single anomaly and the influence of additional cytogenetic aberrations in primary myelodysplastic syndromes

artículo científico publicado en 2012

Progression to large B-cell lymphoma in splenic marginal zone lymphoma: a description of a series of 12 cases

artículo científico publicado en 2001

Reciprocal translocations in myelodysplastic syndromes and chronic myelomonocytic leukemias: review of 5,654 patients with an evaluable karyotype.

artículo científico

Response to imatinib mesylate in patients with hypereosinophilic syndrome.

artículo científico publicado en 2012

Response to lenalidomide in myelodysplastic syndromes with del(5q): influence of cytogenetics and mutations.

artículo científico publicado en 2013

Results of the PETHEMA ALL-96 trial in elderly patients with Philadelphia chromosome-negative acute lymphoblastic leukemia

artículo científico publicado en 2006

Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma.

artículo científico publicado en 2010

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

artículo científico publicado en 2012

Second Revision of the International Staging System (R2-ISS) for Overall Survival in Multiple Myeloma: A European Myeloma Network (EMN) Report Within the HARMONY Project

artículo científico publicado en 2022

Sequential intravenous-oral ciprofloxacin plus amoxycillin/clavulanic acid shortens hospital stay in infected non severe neutropenic patients

artículo científico publicado en 1997

Serum lactate dehydrogenase level as a prognostic factor in Hodgkin's disease.

artículo científico publicado en 1993

Single nucleotide polymorphism array karyotyping: a diagnostic and prognostic tool in myelodysplastic syndromes with unsuccessful conventional cytogenetic testing

artículo científico publicado en 2013

TET2 overexpression in chronic lymphocytic leukemia is unrelated to the presence of TET2 variations.

artículo científico publicado en 2014

The immunophenotype of different immature, myeloid and B-cell lineage-committed CD34+ hematopoietic cells allows discrimination between normal/reactive and myelodysplastic syndrome precursors.

artículo científico publicado en 2008

The presence of genomic imbalances is associated with poor outcome in patients with burkitt lymphoma treated with dose-intensive chemotherapy including rituximab

artículo científico publicado en 2015

Transcriptome analysis reveals molecular profiles associated with evolving steps of monoclonal gammopathies.

artículo científico publicado en 2014

Transient t(11;17)(q14;q12) in patient with chronic myelogenous leukemia in complete molecular response

artículo científico publicado en 2008

Translocation (15;17)(q22;q21) in a patient with Klinefelter syndrome

artículo científico publicado en 1996

Translocation t(1;9) is a recurrent cytogenetic abnormality associated with progression of essential thrombocythemia patients displaying the JAK2 V617F mutation.

artículo científico publicado en 2011

Treatment of High-Risk Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia in Adolescents and Adults According to Early Cytologic Response and Minimal Residual Disease After Consolidation Assessed by Flow Cytometry: Final Results of the P

artículo científico publicado en 2014

Treatment of young patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia using increased dose of imatinib and deintensified chemotherapy before allogeneic stem cell transplantation

artículo científico publicado en 2012

Trisomies 8 and 20 in desmoid tumors

artículo científico publicado en 1996

Trisomy/ tetrasomy of chromosome 8 and +i(8q) as the sole chromosome abnormality in three adult patients with myelomonocytic leukemia

artículo científico publicado en 2000

Uniparental disomy causes deficiencies of vitamin K-dependent proteins

artículo científico publicado en 2016

Validation and clinical evaluation of a UHPLC method with fluorescence detector for plasma quantification of doxorubicin and doxorubicinol in haematological patients

artículo científico publicado en 2014

[Prognostic influence of immunological subtypes of T-cell acute lymphoblastic leukemia. Study of 81 patients]

artículo científico publicado en 2006

del(7q) in chronic B-cell lymphoid malignancies

scientific article published on 01 February 1997

geneCBR: a translational tool for multiple-microarray analysis and integrative information retrieval for aiding diagnosis in cancer research.

artículo científico publicado en 2009