Filtros de búsqueda

Lista de obras de

A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitro

artículo científico publicado en 2015

Advances in the Understanding of the Cannabinoid Receptor 1 - Focusing on the Inverse Agonists Interactions

artículo científico publicado en 2018

Antimalarial Activity of Physalins B, D, F, and G

artículo científico publicado el 28 de septiembre de 2011

At the interface: crystal structures of phospholipases A2

artículo científico publicado en 1998

Bio-Inspired Algorithms Applied to Molecular Docking Simulations

artículo científico publicado el 1 de enero de 2011

Bioinformatics tools for screening of antiparasitic drugs.

artículo científico publicado en 2009

CDK9 a potential target for drug development.

scientific article published on May 2008

Combining molecular dynamics and docking simulations of the cytidine deaminase from Mycobacterium tuberculosis H37Rv

artículo científico publicado en 2011

Computational methods for calculation of ligand-binding affinity.

artículo científico publicado en 2008

Conformation and lytic activity of eumenine mastoparan: a new antimicrobial peptide from wasp venom.

artículo científico publicado en 2004

Crotacetin, a novel snake venom C-type lectin homolog of convulxin, exhibits an unpredictable antimicrobial activity.

artículo científico publicado en 2006

Crystal structure and molecular dynamics studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis associated with acyclovir.

artículo científico publicado en 2011

Crystal structure determination and dynamic studies of Mycobacterium tuberculosis Cytidine deaminase in complex with products.

artículo científico publicado en 2011

Crystal structure of hemoglobin from the maned wolf (Chrysocyon brachyurus) using synchrotron radiation

artículo científico publicado en 2003

Crystal structure of human PNP complexed with hypoxanthine and sulfate ion.

artículo científico publicado en 2005

Crystal structure of piratoxin-I: a calcium-independent, myotoxic phospholipase A2-homologue from Bothrops pirajai venom

artículo científico publicado en 1998

Crystallization and preliminary X-ray diffraction analysis of a eumenine mastoparan toxin: a new class of mast-cell degranulating peptide in the wasp venom

artículo científico publicado en 2000

Crystallization and preliminary X-ray diffraction analysis of an anti-H(O) lectin from Lotus tetragonolobus seeds.

artículo científico publicado en 2006

Crystallization and preliminary X-ray diffraction analysis of the lectin fromCanavalia gladiataseeds

artículo científico publicado en 2004

Crystallization, preliminary X-ray analysis and Patterson search of a new aspartic protease isolated from human urine

artículo científico publicado en 1998

Crystallization, preliminary X-ray analysis and molecular-replacement solution of haemoglobin-II from the fish matrinxã (Brycon cephalus).

artículo científico publicado en 2003

Crystallization, preliminary X-ray analysis and molecular-replacement solution of the carboxy form of haemoglobin I from the fish Brycon cephalus

artículo científico publicado en 2000

Crystallization, preliminary X-ray diffraction analysis and Patterson search of oxyhaemoglobin I from the wolf (Chrysocyon brachiurus)

scientific article published on 01 September 1999

Crystallographic and pre-steady-state kinetics studies on binding of NADH to wild-type and isoniazid-resistant enoyl-ACP(CoA) reductase enzymes from Mycobacterium tuberculosis

artículo científico publicado en 2006

Crystallographic and spectroscopic characterization of a molecular hinge: conformational changes in bothropstoxin I, a dimeric Lys49-phospholipase A2 homologue.

artículo científico publicado en 1998

Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis

artículo científico publicado en 2007

Determining the structural basis for specificity of ligands using crystallographic screening.

artículo científico publicado en 2006

Development of CDK-targeted scoring functions for prediction of binding affinity

artículo científico publicado en 2018

Development of a machine-learning model to predict Gibbs free energy of binding for protein-ligand complexes

scientific article published on 07 June 2018

Development of machine learning models to predict inhibition of 3-dehydroquinate dehydratase.

artículo científico publicado en 2018

Effects of the magnesium and chloride ions and shikimate on the structure of shikimate kinase fromMycobacterium tuberculosis

artículo científico publicado en 2007

Evaluation of ligand-binding affinity using polynomial empirical scoring functions

scientific article published on 07 August 2008

Experimental approaches to evaluate the thermodynamics of protein-drug interactions.

artículo científico publicado en 2008

Expression and purification of human respiratory syncytial virus recombinant fusion protein.

artículo científico publicado en 2008

Expression, purification, and circular dichroism analysis of human CDK9.

artículo científico publicado en 2006

Genomic databases and the search of protein targets for protozoan parasites.

scientific article published on March 2009

Halogen atoms in the modern medicinal chemistry: hints for the drug design.

artículo científico publicado en 2010

Identification of new potential Mycobacterium tuberculosis shikimate kinase inhibitors through molecular docking simulations.

artículo científico publicado en 2011

In silico and in vitro: identifying new drugs.

artículo científico publicado en 2008

Molecular Dynamics Simulations of Protein Targets Identified in Mycobacterium tuberculosis

artículo científico publicado el 1 de enero de 2011

Molecular Models of Tryptophan Synthase From Mycobacterium tuberculosis Complexed With Inhibitors

scientific article published on 01 January 2006

Molecular dynamics studies of a hexameric purine nucleoside phosphorylase.

artículo científico publicado en 2009

Molecular modeling and dynamics simulation of human cyclin-dependent kinase 3 complexed with inhibitors

artículo científico publicado en 2009

Molecular modeling and dynamics simulations of PNP from Streptococcus agalactiae.

artículo científico publicado en 2008

Molecular modeling and dynamics studies of Shikimate Kinase from Bacillus anthracis.

artículo científico publicado en 2008

Molecular modeling and dynamics studies of cytidylate kinase from Mycobacterium tuberculosis H37Rv.

artículo científico publicado en 2008

Molecular modeling and dynamics studies of purine nucleoside phosphorylase from Bacteroides fragilis.

artículo científico publicado en 2009

Molecular modeling and small angle X-ray scattering studies of Hoplosternum littorale cathodic haemoglobin.

artículo científico publicado en 2004

Molecular modeling, dynamics and docking studies of purine nucleoside phosphorylase from Streptococcus pyogenes.

artículo científico publicado en 2009

Molecular models of NS3 protease variants of the Hepatitis C virus

artículo científico publicado en 2005

Molecular models of cyclin-dependent kinase 1 complexed with inhibitors.

artículo científico publicado en 2004

Molecular models of protein targets from Mycobacterium tuberculosis.

artículo científico publicado en 2005

Native crystal structure of a nitric oxide-releasing lectin from the seeds of Canavalia maritima.

artículo científico publicado en 2005

New crystal forms of Diocleinae lectins in the presence of different dimannosides.

artículo científico publicado en 2006

Opinion Paper: Targeting Multiple Cyclin-Dependent Kinases (CDKs): A New Strategy for Molecular Docking Studies.

artículo científico publicado en 2015

Optimized Virtual Screening Workflow. Towards Target-Based Polynomial Scoring Functions for HIV-1 Protease.

artículo científico publicado en 2017

Parmodel: a web server for automated comparative modeling of proteins

artículo científico publicado en 2004

Phosphate closes the solution structure of the 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) from Mycobacterium tuberculosis

artículo científico publicado en 2006

Pre-clinical effects of metformin and aspirin on the cell lines of different breast cancer subtypes.

artículo científico publicado en 2018

Preliminary cryocrystallography analysis of an eumenine mastoparan toxin isolated from the venom of the wasp Anterhynchium flavomarginatum micado

scientific article published on 01 February 2001

Protein crystallography in drug discovery.

scientific article published on December 2008

Protein kinases as targets for antiparasitic chemotherapy drugs.

artículo científico publicado en 2007

Protein targets for development of drugs against Mycobacterium tuberculosis

artículo científico publicado en 2011

Protein-drug interaction studies for development of drugs against Plasmodium falciparum.

scientific article published on March 2009

Protein-drug interactions

artículo científico publicado en 2008

Purification and partial characterization of cathepsin D from porcine (Sus scrofa) liver using affinity chromatography.

artículo científico publicado en 1998

Purification, crystallization and Patterson search of haemoglobin IV from the armoured catfish Liposarcus anisitsi

scientific article published on 23 August 2001

Purification, crystallization and preliminary X-ray analysis of haemoglobin I from the armoured catfish Liposarcus anisitsi

scientific article published on 01 April 2000

Purification, crystallization and preliminary x-ray diffraction analysis of carboxyhaemoglobin-II from the fish Piaractus mesopotamicus (pacu)

artículo científico publicado en 2000

Purification, partial characterization and preliminary X-ray diffraction analysis of a mannose-specific lectin from Cymbosema roseum seeds.

artículo científico publicado en 2006

Rattlesnake hemoglobins: Functional properties and tetrameric stability.

artículo científico publicado en 2006

Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA)

artículo científico publicado en 2012

SKPDB: a structural database of shikimate pathway enzymes.

artículo científico publicado en 2010

Selection of targets for drug development against protozoan parasites.

artículo científico publicado en 2009

Shikimate kinase, a protein target for drug design.

artículo científico publicado en 2014

Shikimate kinase: a potential target for development of novel antitubercular agents.

artículo científico publicado en 2007

Structural and functional analyses of Mycobacterium tuberculosis Rv3315c-encoded metal-dependent homotetrameric cytidine deaminase

artículo científico publicado en 2010

Structural and functional characterization of N-terminally blocked peptides isolated from the venom of the social wasp Polybia paulista.

artículo científico publicado en 2004

Structural basis for chemical inhibition of CDK2.

artículo científico publicado en 1996

Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

scientific article published on April 1996

Structural bioinformatics study of EPSP synthase from Mycobacterium tuberculosis.

artículo científico publicado en 2003

Structural studies of human purine nucleoside phosphorylase: towards a new specific empirical scoring function

artículo científico publicado en 2008

Structural studies of prephenate dehydratase from Mycobacterium tuberculosis H37Rv by SAXS, ultracentrifugation, and computational analysis.

artículo científico publicado en 2008

Structure of a Lys49-Phospholipase A2 homologue isolated from the venom of Bothrops nummifer (jumping viper)

scientific article published on 01 February 1999

Structure of chorismate synthase from Mycobacterium tuberculosis.

artículo científico publicado en 2006

Structure of human PNP complexed with ligands.

artículo científico publicado en 2005

Structure of human uropepsin at 2.45 A resolution

artículo científico publicado en 2001

Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid

scientific journal article

Structure-based virtual screening.

artículo científico publicado en 2010

Structures of human purine nucleoside phosphorylase complexed with inosine and ddI

artículo científico publicado en 2004

Supervised Machine Learning Methods Applied to Predict Ligand-Binding Affinity

artículo científico publicado en 2017

Taba: A Tool to Analyze the Binding Affinity

artículo científico publicado en 2019

Targeting imidazoline site on monoamine oxidase B through molecular docking simulations.

artículo científico publicado en 2012

The Impact of Crystallographic Data for the Development of Machine Learning Models to Predict Protein-Ligand Binding Affinity

artículo científico publicado en 2021

The inhibition of 5-enolpyruvylshikimate-3-phosphate synthase as a model for development of novel antimicrobials.

artículo científico publicado en 2007

The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated diseases--a review.

artículo científico publicado en 2005

Understanding the Structural Basis for Inhibition of Cyclin-Dependent Kinases. New Pieces in the Molecular Puzzle

artículo científico publicado en 2016

cDNA cloning and 1.75 A crystal structure determination of PPL2, an endochitinase and N-acetylglucosamine-binding hemagglutinin from Parkia platycephala seeds

artículo científico publicado en 2006