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A Functionally Superior Second-Generation Vector Expressing an Aurora Kinase-A-Specific T-Cell Receptor for Anti-Leukaemia Adoptive Immunotherapy.

artículo científico publicado en 2016

A Promising Vector for TCR Gene Therapy: Differential Effect of siRNA, 2A Peptide, and Disulfide Bond on the Introduced TCR Expression.

artículo científico publicado en 2012

A novel human-derived antibody against NY-ESO-1 improves the efficacy of chemotherapy

artículo científico publicado en 2013

A novel role for Notch ligand Delta-1 as a regulator of human Langerhans cell development from blood monocytes.

artículo científico publicado en 2005

Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells.

artículo científico publicado en 2018

Activity of interleukin 6 in the differentiation of monocytes to macrophages and dendritic cells

scientific article published on 01 May 2000

Acute interstitial pneumonitis during chemotherapy for haematological malignancy.

artículo científico publicado en 2005

Additional t(11;17)(q23;q21) in a patient with Philadelphia-positive mixed lineage antigen-expressing leukemia

scientific article published on 01 April 2001

Adoptive Transfer of MAGE-A4 T-cell Receptor Gene-Transduced Lymphocytes in Patients with Recurrent Esophageal Cancer.

artículo científico publicado en 2015

Adoptive immunotherapy of cancer utilizing genetically engineered lymphocytes.

artículo científico

Adoptive transfer of genetically engineered WT1-specific cytotoxic T lymphocytes does not induce renal injury

artículo científico publicado en 2014

Adoptive transfer of genetically modified Wilms' tumor 1-specific T cells in a novel malignant skull base meningioma model

artículo científico publicado en 2013

Adult T cell leukaemia cells are of CD4+ CDw29+ T cell origin and secrete a B cell differentiation factor

Alloantigen-induced T-cell proliferation: Lyt phenotype of responding cells and blocking of proliferation by Lyt antisera

artículo científico publicado en 1980

Analysis of peripheral and local anti-tumor immune response in esophageal cancer patients after NY-ESO-1 protein vaccination

scientific article published on 01 November 2008

Antibody response against NY-ESO-1 in CHP-NY-ESO-1 vaccinated patients

artículo científico publicado en 2007

Antibody responses against NY-ESO-1 and HER2 antigens in patients vaccinated with combinations of cholesteryl pullulan (CHP)-NY-ESO-1 and CHP-HER2 with OK-432

artículo científico publicado en 2009

Antigen delivery targeted to tumor-associated macrophages overcomes tumor immune resistance

scientific article published on 11 February 2019

Antigen-Receptor Gene-Modified T Cells For Treatment Of Glioma

artículo científico publicado el 1 de enero de 2012

Antileukemia multifunctionality of CD4(+) T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer.

artículo científico publicado en 2015

Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination

artículo científico publicado en 2018

Attempt to Harvest a Sufficient Number of Mononuclear Cells in an Appropriate Blood Product Volume By Modification of the Default Apheresis Setting

artículo científico

CD21S antigen expression in tumour cells of diffuse large B-cell lymphomas is an independent prognostic factor indicating better overall survival.

artículo científico publicado en 2004

CD8+CD122+ regulatory T cells recognize activated T cells via conventional MHC class I-alphabetaTCR interaction and become IL-10-producing active regulatory cells.

artículo científico publicado en 2008

CD8+CD122+CD49dlow regulatory T cells maintain T-cell homeostasis by killing activated T cells via Fas/FasL-mediated cytotoxicity

artículo científico publicado en 2016

Cell surface antigens of human malignant melanoma. III. Recognition of autoantibodies with unusual characteristics

artículo científico publicado el 1 de marzo de 1977

Cell surface antigens of human renal cancer defined by autologous typing

artículo científico publicado el 19 de septiembre de 1979

Cell surface antigens of murine leukemias induced by radiation leukemia virus. Recognition of individually distinct cell surface antigens by cytotoxic T cells on leukemias expressing crossreactive transplantation antigens

artículo científico publicado en 1986

Cell-mediated cytotoxicity for cultured autologous melanoma cells

artículo científico publicado el 15 de julio de 1979

Classification of current anticancer immunotherapies

artículo científico publicado en 2014

Clinical Implications of CD4+CD25+Foxp3+Regulatory T Cell Frequencies After CHP-MAGE-A4 Cancer Vaccination

scientific article published on 01 March 2018

Clinical relevance of antigen spreading pattern induced by CHP-MAGE-A4 cancer vaccination.

artículo científico publicado en 2016

Clinicopathologic significance of loss of CD19 expression in diffuse large B-cell lymphoma.

artículo científico publicado en 2007

Co-introduced functional CCR2 potentiates in vivo anti-lung cancer functionality mediated by T cells double gene-modified to express WT1-specific T-cell receptor.

artículo científico publicado en 2013

Comparison of diagnostic criteria for disseminated intravascular coagulation (DIC): diagnostic criteria of the International Society of Thrombosis and Hemostasis and of the Japanese Ministry of Health and Welfare for overt DIC.

artículo científico publicado en 2003

Cyclin D1 expression is useful as a prognostic indicator for advanced esophageal carcinomas, but not for superficial tumors

artículo científico publicado en 2000

Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera

artículo científico publicado el 1 de abril de 1979

Cytotoxic reactions of murine lymphoid cells studied with a tritiated proline microcytotoxicity test

artículo científico publicado el 1 de febrero de 1975

De novo CD5+ diffuse large B-cell lymphoma: a clinicopathologic study of 109 patients.

artículo científico publicado en 2002

De novo CD5-positive diffuse large B-cell lymphoma of the temporal bone presenting with an external auditory canal tumor.

artículo científico publicado en 2006

De novo CD5-positive diffuse large B-cell lymphoma: clinical characteristics and therapeutic outcome

artículo científico publicado en 1999

Decreased ADAMTS13 activity in plasma from patients with thrombotic thrombocytopenic purpura.

artículo científico publicado en 2006

Defining the critical hurdles in cancer immunotherapy

artículo científico publicado en 2011

Definition of a unique cell surface antigen of mouse leukemia RL male 1 by cell-mediated cytotoxicity

artículo científico publicado el 1 de julio de 1979

Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cells

artículo científico publicado en 2005

Detection of the CBFB/MYH11 fusion gene in de novo acute myeloid leukemia (AML): a single-institution study of 224 Japanese AML patients.

artículo científico publicado en 2006

Determination of cellularly processed HLA-A2402-restricted novel CTL epitopes derived from two cancer germ line genes, MAGE-A4 and SAGE

artículo científico publicado en 2005

Development of Engineered T Cells Expressing a Chimeric CD16-CD3ζ Receptor to Improve the Clinical Efficacy of Mogamulizumab Therapy Against Adult T-Cell Leukemia

artículo científico publicado en 2016

Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia.

artículo científico publicado en 2013

Differential cell division history between neutrophils and macrophages in their development from granulocyte-macrophage progenitors.

artículo científico publicado en 2006

Differential regulatory function of resting and preactivated allergen-specific CD4+ CD25+ regulatory T cells in Th2-type airway inflammation

scientific article published on 01 November 2008

Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion-exchange method

artículo científico publicado en 2022

Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients

artículo científico publicado en 2013

Early tumor regression following severe lung injury after allogeneic stem cell transplantation in a patient with renal cell carcinoma

artículo científico publicado en 2007

Efficient Ex Vivo Generation of Human Dendritic Cells from Mobilized CD34p+ Peripheral Blood Progenitors

artículo científico publicado el 1 de octubre de 2001

Efficient tumor regression by adoptively transferred CEA-specific CAR-T cells associated with symptoms of mild cytokine release syndrome.

artículo científico publicado en 2016

Engineering hybrid exosomes by membrane fusion with liposomes

artículo científico publicado en 2016

Epirubicin, Identified Using a Novel Luciferase Reporter Assay for Foxp3 Inhibitors, Inhibits Regulatory T Cell Activity

artículo científico publicado en 2016

Establishment of animal models to analyze the kinetics and distribution of human tumor antigen-specific CD8+ T cells

artículo científico publicado el 13 de marzo de 2013

Exosomal regulation of lymphocyte homing to the gut

artículo científico publicado en 2019

Exosome-mediated regulation of tumor immunology

artículo científico publicado en 2018

Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells

artículo científico publicado el 1 de enero de 1975

Expression profiling analysis of the CD5+ diffuse large B-cell lymphoma subgroup: development of a CD5 signature

artículo científico publicado en 2006

Feasibility of gene-immunotherapy using WT1-specific T-cell receptor gene transfer for infant acute lymphoblastic leukemia with MLL gene rearrangement

artículo científico publicado el 18 de marzo de 2011

First Case of Cytokine Release Syndrome after Nivolumab for Gastric Cancer

artículo científico publicado en 2019

Gastric mucosa-associated lymphoid tissue lymphoma with a focal high-grade component diagnosed by EUS and endoscopic mucosal resection for histologic evaluation

artículo científico publicado en 2000

Gemcitabine enhances Wilms’ tumor gene WT1 expression and sensitizes human pancreatic cancer cells with WT1-specific T-cell-mediated antitumor immune response

artículo científico publicado el 24 de mayo de 2011

Gene expression profiling of diffuse large B-Cell lymphomas supervised by CD5 expression

scientific article published on 26 May 2015

Gene expression profiling of peripheral T-cell lymphoma including gammadelta T-cell lymphoma.

artículo científico publicado en 2008

Gene-modified human α/β-T cells expressing a chimeric CD16-CD3ζ receptor as adoptively transferable effector cells for anticancer monoclonal antibody therapy

artículo científico publicado en 2014

Generation of peptide-specific CD8+ T cells by phytohemagglutinin-stimulated antigen-mRNA-transduced CD4+ T cells.

artículo científico publicado en 2006

Glucocorticoid-induced tumor necrosis factor receptor stimulation enhances the multifunctionality of adoptively transferred tumor antigen-specific CD8+ T cells with tumor regression.

artículo científico publicado en 2009

Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell Types

artículo científico publicado en 2016

HER2-specific T-cell immune responses in patients vaccinated with truncated HER2 protein complexed with nanogels of cholesteryl pullulan

artículo científico publicado en 2006

Heterogeneous copy numbers of API2-MALT1 chimeric transcripts in mucosa-associated lymphoid tissue lymphoma

artículo científico publicado el 1 de diciembre de 2003

High establishment efficiency of lymph node stromal cells which spontaneously produce multiple cytokines derived from adult T-cell leukemia/lymphoma patients

artículo científico publicado el 1 de octubre de 1996

High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine.

artículo científico publicado en 2014

Human bone marrow stromal cells simultaneously support B and T/NK lineage development from human haematopoietic progenitors: a principal role for flt3 ligand in lymphopoiesis.

artículo científico publicado en 2012

Human melanoma antigen AH is an autoantigenic ganglioside related to GD2.

artículo científico publicado en 1982

IFN-gamma controls the generation/activation of CD4+ CD25+ regulatory T cells in antitumor immune response.

artículo científico publicado en 2005

IL-2-Dependent ATL cell lines with phenotypes differing from the original leukemia cells

artículo científico publicado el 1 de enero de 1991

Identification of an immunogenic neo-epitope encoded by mouse sarcoma using CXCR3 ligand mRNAs as sensors

artículo científico publicado en 2017

Immunohistochemical expression and clinicopathological assessment of the cancer testis antigens NY-ESO-1 and MAGE-A4 in high-grade soft-tissue sarcoma

artículo científico publicado en 2019

Importance of CD80/CD86-CD28 interactions in the recognition of target cells by CD8+CD122+ regulatory T cells

artículo científico publicado en 2008

Improved expression and reactivity of transduced tumor-specific TCRs in human lymphocytes by specific silencing of endogenous TCR.

artículo científico publicado en 2009

In vitro stimulation of CD8 and CD4 T cells by dendritic cells loaded with a complex of cholesterol-bearing hydrophobized pullulan and NY-ESO-1 protein: Identification of a new HLA-DR15-binding CD4 T-cell epitope.

artículo científico publicado en 2006

In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines.

artículo científico publicado en 2006

Increased soluble fibrin in plasma of patients with disseminated intravascular coagulation

artículo científico publicado en 2003

Increased soluble fibrin monomer and soluble thrombomodulin levels in non-insulin-dependent diabetes mellitus

artículo científico publicado el 1 de julio de 1997

Induction of immune response against NY-ESO-1 by CHP-NY-ESO-1 vaccination and immune regulation in a melanoma patient

artículo científico publicado en 2008

Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector.

artículo científico publicado en 2007

Interleukin-17 induces an atypical M2-like macrophage subpopulation that regulates intestinal inflammation

artículo científico publicado en 2014

Intracellular tumor-associated antigens represent effective targets for passive immunotherapy.

artículo científico publicado en 2012

Intratumoral injection of Propionibacterium acnes suppresses malignant melanoma by enhancing Th1 immune responses.

artículo científico publicado en 2011

Limited expression of cancer-testis antigens in renal cell carcinoma patients

artículo científico publicado en 2012

Ly phenotype of cytotoxic T cells for syngeneic tumor

artículo científico publicado en 1976

Manipulation of human early T lymphopoiesis by coculture on human bone marrow stromal cells: potential utility for adoptive immunotherapy.

artículo científico publicado en 2012

Molecular and phenotypic analysis of Philadelphia chromosome-positive bilineage leukemia: possibility of a lineage switch from T-lymphoid leukemic progenitor to myeloid cells.

artículo científico publicado en 2006

Myelodysplastic syndrome of del 20q with plasma cell dysplasia.

artículo científico publicado en 2011

Nanogel-based immunologically stealth vaccine targets macrophages in the medulla of lymph node and induces potent antitumor immunity

artículo científico publicado en 2014

Notch ligand Delta-1 differentially modulates the effects of gp130 activation on interleukin-6 receptor alpha-positive and -negative human hematopoietic progenitors

artículo científico publicado en 2007

Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked antileukemia reactivity and safety

artículo científico publicado el 14 de junio de 2011

Overcoming regulatory T-cell suppression by a lyophilized preparation of Streptococcus pyogenes

artículo científico publicado en 2013

Peptide Vaccine Induces Enhanced Tumor Growth Associated with Apoptosis Induction in CD8+ T Cells

artículo científico publicado el 23 de agosto de 2010

Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor α2 chain in recurrent malignant glioma patients with HLA-A*24/A*02 allele.

artículo científico publicado en 2012

Post-immune UV irradiation induces Tr1-like regulatory T cells that suppress humoral immune responses

artículo científico publicado en 2007

Prognostic value of MAGEA4 in primary lung cancer depends on subcellular localization and p53 status

artículo científico publicado en 2018

RHAMM-R3 peptide vaccination in patients with acute myeloid leukemia, myelodysplastic syndrome, and multiple myeloma elicits immunologic and clinical responses

scientific article published on 31 October 2007

Rapid alphabeta TCR-mediated responses in gammadelta T cells transduced with cancer-specific TCR genes.

artículo científico publicado en 2009

Reduced Cd4+Cd25+ T cells in patients with idiopathic thrombocytopenic purpura.

artículo científico publicado en 2006

Regulatory T cell-resistant CD8+ T cells induced by glucocorticoid-induced tumor necrosis factor receptor signaling.

artículo científico publicado en 2008

Role of SEREX-defined immunogenic wild-type cellular molecules in the development of tumor-specific immunity

artículo científico publicado el 27 de noviembre de 2001

Safety and persistence of WT1-specific T-cell receptor gene-transduced lymphocytes in patients with AML and MDS.

artículo científico publicado en 2017

Serological analysis of cell surface antigens of malignant human brain tumors

artículo científico publicado el 1 de octubre de 1978

Serological response of melanoma patients receiving melanoma cell vaccines. I. Autologous cultured melanoma cells

artículo científico publicado en 1982

Serum immunoglobulin E response as a marker for unfavorable prognosis following cholesteryl pullulan-MAGE A4 vaccination.

artículo científico publicado en 2018

Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation.

artículo científico publicado en 2017

Stimulation through very late antigen-4 and -5 improves the multifunctionality and memory formation of CD8⁺ T cells.

artículo científico publicado en 2014

Surface phenotype of nonadherent peritoneal cells effecting cell-mediated cytotoxicity in vitro for allogeneic and syngeneic murine sarcoma cells

artículo científico publicado el 1 de abril de 1976

Systemic CD8+ T cell-mediated tumoricidal effects by intratumoral treatment of oncolytic herpes simplex virus with the agonistic monoclonal antibody for murine glucocorticoid-induced tumor necrosis factor receptor

artículo científico publicado en 2014

T cell immunomonitoring and tumor responses in patients immunized with a complex of cholesterol-bearing hydrophobized pullulan (CHP) and NY-ESO-1 protein.

artículo científico publicado en 2007

T-cell receptor gene therapy targeting melanoma-associated antigen-A4 inhibits human tumor growth in non-obese diabetic/SCID/γcnull mice.

artículo científico publicado en 2011

The membrane proteinase 3 expression on neutrophils was downregulated after treatment with infliximab in patients with rheumatoid arthritis.

artículo científico publicado en 2008

Time-dependent transition of the immunoglobulin G subclass and immunoglobulin E response in cancer patients vaccinated with cholesteryl pullulan-melanoma antigen gene-A4 nanogel.

artículo científico publicado en 2016

Translational research of cancer vaccine

artículo científico publicado el 1 de enero de 2011

Tumor progression inhibits the induction of multifunctionality in adoptively transferred tumor-specific CD8+ T cells.

artículo científico publicado en 2009

Tumor-Specific Antigens

artículo científico publicado el 1 de enero de 1980

Tumor-specific crosslinking of GITR as costimulation for immunotherapy

artículo científico publicado en 2010

Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals.

artículo científico publicado en 2010

UV irradiation of immunized mice induces type 1 regulatory T cells that suppress tumor antigen specific cytotoxic T lymphocyte responses

artículo científico publicado el 12 de enero de 2011

siRNA-mediated silencing of PD-1 ligands enhances tumor-specific human T-cell effector functions

artículo científico publicado el 24 de noviembre de 2011